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The map label for this gene is mltC [C]

Identifier: 161525614

GI number: 161525614

Start: 2659181

End: 2660305

Strand: Reverse

Name: mltC [C]

Synonym: Bmul_2444

Alternate gene names: 161525614

Gene position: 2660305-2659181 (Counterclockwise)

Preceding gene: 161525617

Following gene: 161525604

Centisome position: 77.14

GC content: 70.4

Gene sequence:

>1125_bases
ATGAACGCTTGGTTATCGTGGCGTCCTAACGAGCGGCATGCGCAATTCGTGCGCGACATGCTGCGTCGCGGGACGCGTGT
CAGCCACCATCTGTTCAGCGTCGTCGGCTGTTTCGCCGTCGCCATCGCGCTGGCGCTCTGGCTGCTGCCGACCGTGCGCG
GCACGCTGGCCGCAAAGCTGATGCCGATCGTGTCGGCGGCCGTCGAGGCCGGTCCGGCGCGTCTGCTGTCCGGCCATCCG
CTGCCGAATTTCGCGCCGGCCGGCGCACAGCCGCAACCGCAAGACGACGGTCCGGAGACCGATGCGCTCGCCGCCGATCT
CGATGTCGCGGCGGAAGCCACGGCCGCCGCGCAGAACGACGCATCGGACGTGGCCCGGAGCGGCCCGTCGCCGGTGGCGC
TCGCGAAGCTGATCCCGACGCAGCGCGTGCCGGCCGATGCGCGCGACGATCGTGCGCTGGCCTCGAACCGCGAACAGGCG
CTCGTCGCGACGTATCTGTCGCGCCGCTATCACGTCGCGCAGGAACCGCTCGGCCGGCTCGTGAAGGCCGCGTTCGAAAC
CGGCCGCGACGTCGGCCTCGATCCGCTGCTGCTGCTCGCCGTGATGGCGATCGAATCGGGCTTCAATCCGTATGCGGAAA
GCGGCGTCGGCGCGCAGGGCCTGATGCAGGTGATGTCGAAGGTCCATTCCGACAAGTTCGAATATTTCGGCGGCACCGAC
ACGGCGCTGCAGCCGATCGCGAATCTGCAGGTCGGCGCGCTCGTGCTGAAGGACTGCATCGCGCGCGGCGGCTCGCTGGC
GAACGGGCTGCGCCTCTACAACGGCTCGACGAATCCGGACGACAACGGCTACGGTCAGAAGGTGATGGCCGAGCGCGGTC
GTCTGCGCGATGTCGCCCGCGGCCGCAGCGTGCCGATCAATGCGCCGCAGGCGCCGGCCAAGCCGATCGTCACCGCGGCG
GTCACGACCGCGGCGGCCGGCGGCGCGAAGCGCGTGCACGTGACGCTCGACGGCGCACAGCCGCTCGCCGCGAAGACGGC
GCCGCCGAAGGCGCCGCAGCAGGCCGACGCGAGCGTCGATACGTCGAAGCAGGCGCGCGACGATCACTCGGATCTCGGCG
CGTAA

Upstream 100 bases:

>100_bases
CCCGACCAAGGCGTGCGGCGTCGTGATTCAGCGGCGCGTTTTCTGTCTCGCCAGCGAGCCGGGCGAGCCGCACGAGTCAT
GTTCATGGGAGATGATCTGA

Downstream 100 bases:

>100_bases
CGTCGGATTTACTCCGCGCCGAAATGGAAAAGACACCCTCGGGTGTCTTTTTTCGTTTGGAGGGGCGCAGCGGCGGCGCG
ATCGCGCCGCGGCGACTCAG

Product: lytic transglycosylase catalytic

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: Transglycosylase; Transglycosylase SLT Family Protein; Transglycosylase SLT Family; Lytic Transglycosylase; Transglycosylase SLT Domain-Containing Lipoprotein; Transmembrane Protein; Transglycosylase Protein; Transglycosylase SLT Domain-Containing; Transmembrane Transglycosylase SLT Family Protein

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MNAWLSWRPNERHAQFVRDMLRRGTRVSHHLFSVVGCFAVAIALALWLLPTVRGTLAAKLMPIVSAAVEAGPARLLSGHP
LPNFAPAGAQPQPQDDGPETDALAADLDVAAEATAAAQNDASDVARSGPSPVALAKLIPTQRVPADARDDRALASNREQA
LVATYLSRRYHVAQEPLGRLVKAAFETGRDVGLDPLLLLAVMAIESGFNPYAESGVGAQGLMQVMSKVHSDKFEYFGGTD
TALQPIANLQVGALVLKDCIARGGSLANGLRLYNGSTNPDDNGYGQKVMAERGRLRDVARGRSVPINAPQAPAKPIVTAA
VTTAAAGGAKRVHVTLDGAQPLAAKTAPPKAPQQADASVDTSKQARDDHSDLGA

Sequences:

>Translated_374_residues
MNAWLSWRPNERHAQFVRDMLRRGTRVSHHLFSVVGCFAVAIALALWLLPTVRGTLAAKLMPIVSAAVEAGPARLLSGHP
LPNFAPAGAQPQPQDDGPETDALAADLDVAAEATAAAQNDASDVARSGPSPVALAKLIPTQRVPADARDDRALASNREQA
LVATYLSRRYHVAQEPLGRLVKAAFETGRDVGLDPLLLLAVMAIESGFNPYAESGVGAQGLMQVMSKVHSDKFEYFGGTD
TALQPIANLQVGALVLKDCIARGGSLANGLRLYNGSTNPDDNGYGQKVMAERGRLRDVARGRSVPINAPQAPAKPIVTAA
VTTAAAGGAKRVHVTLDGAQPLAAKTAPPKAPQQADASVDTSKQARDDHSDLGA
>Mature_374_residues
MNAWLSWRPNERHAQFVRDMLRRGTRVSHHLFSVVGCFAVAIALALWLLPTVRGTLAAKLMPIVSAAVEAGPARLLSGHP
LPNFAPAGAQPQPQDDGPETDALAADLDVAAEATAAAQNDASDVARSGPSPVALAKLIPTQRVPADARDDRALASNREQA
LVATYLSRRYHVAQEPLGRLVKAAFETGRDVGLDPLLLLAVMAIESGFNPYAESGVGAQGLMQVMSKVHSDKFEYFGGTD
TALQPIANLQVGALVLKDCIARGGSLANGLRLYNGSTNPDDNGYGQKVMAERGRLRDVARGRSVPINAPQAPAKPIVTAA
VTTAAAGGAKRVHVTLDGAQPLAAKTAPPKAPQQADASVDTSKQARDDHSDLGA

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 39192; Mature: 39192

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHCCCHHHCCC
>Mature Secondary Structure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CHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA