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The map label for this gene is trxB [H]

Identifier: 161525594

GI number: 161525594

Start: 2637815

End: 2638777

Strand: Direct

Name: trxB [H]

Synonym: Bmul_2424

Alternate gene names: 161525594

Gene position: 2637815-2638777 (Clockwise)

Preceding gene: 161525590

Following gene: 161525595

Centisome position: 76.49

GC content: 65.52

Gene sequence:

>963_bases
ATGTCCACGCCCAAACACGCCAAAGTCCTGATTCTCGGTTCCGGCCCCGCCGGCTACACGGCCGCCGTCTATGCGGCCCG
CGCCAATTTGTCGCCGGTGCTGATCACCGGCATCGCGCAGGGCGGGCAGCTGATGACGACGACGGACGTCGAAAACTGGC
CGGCGGACGCGAAAGGCGTGCAAGGTCCGGAACTGATGGCGCGCTTTCTCGAGCACGCCGAGCGCTTCAATACCGAGATC
GTGTTCGACCACATCCACACCGCGAAGCTGCACGAACGGCCGATCCGGCTGATCGGCGATTCCGGCGAATATACCTGCGA
CGCGCTGATCATCGCGACCGGCGCATCGGCGCAGTATCTCGGCCTGCCGTCCGAGGAAGCGTTCATGGGCAAGGGCGTGT
CGGCCTGCGCGACCTGCGACGGCTTCTTCTACCGCGGCCAGGACGTCGCCGTGATCGGCGGCGGCAACACGGCCGTCGAG
GAAGCGCTCTACCTGACCGGCATCGCGAAGAAGGTCACGGTGATTCACCGCCGCGACAAGTTCCGCGCGGAGCCGATCCT
CGTCGACCGTCTGCTCGAGAAGCAAAAGGAAGGCGTCGTCGACATCAAGTGGGATCACGTACTCGACGAAGTGACGGGCG
AGGACTCGGGCGTGACCGGCGTGCGGATCAAGCACGTGAAGACCGGCGCGACCGAAGACATCGCGGTGCAGGGCCTGTTC
GTCGCGATCGGCCACAAGCCGAACACCGATCTGTTCCAGGGCCAGCTCGAGATGAAGGACGGCTATATCCTGACGAAGAG
CGGCCTGCAGGGCAACGCGACGGCGACGAGCGTGCCGGGCGTGTTCGCGGCCGGCGACGTGCAGGACAACGTCTACCGTC
AGGCGATCACCAGCGCCGGCACCGGCTGCATGGCCGCGCTCGACGCACAGCGCTACCTCGAAAGCCTGCACGACAAGAAG
TAA

Upstream 100 bases:

>100_bases
TGCGCGTCTGATACCCATCTACGCACGGCATCCCGGTCAACCCGGACCGTCCGGCGAGCCGCACCGCGCCCGCCGTGGCC
GTCTTTTACGGATTTCGCAC

Downstream 100 bases:

>100_bases
GCCGCAAGCGCCGCCGCGTCGGGCGCTACAATGGCGGCCGCTGCCGCGAAGCAGGCCAGGCCGGAGCCGCTGCCCGTCGC
GCAGCGGCTTTTTTGTGCCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGVQGPELMARFLEHAERFNTEI
VFDHIHTAKLHERPIRLIGDSGEYTCDALIIATGASAQYLGLPSEEAFMGKGVSACATCDGFFYRGQDVAVIGGGNTAVE
EALYLTGIAKKVTVIHRRDKFRAEPILVDRLLEKQKEGVVDIKWDHVLDEVTGEDSGVTGVRIKHVKTGATEDIAVQGLF
VAIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATATSVPGVFAAGDVQDNVYRQAITSAGTGCMAALDAQRYLESLHDKK

Sequences:

>Translated_320_residues
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGVQGPELMARFLEHAERFNTEI
VFDHIHTAKLHERPIRLIGDSGEYTCDALIIATGASAQYLGLPSEEAFMGKGVSACATCDGFFYRGQDVAVIGGGNTAVE
EALYLTGIAKKVTVIHRRDKFRAEPILVDRLLEKQKEGVVDIKWDHVLDEVTGEDSGVTGVRIKHVKTGATEDIAVQGLF
VAIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATATSVPGVFAAGDVQDNVYRQAITSAGTGCMAALDAQRYLESLHDKK
>Mature_319_residues
STPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGVQGPELMARFLEHAERFNTEIV
FDHIHTAKLHERPIRLIGDSGEYTCDALIIATGASAQYLGLPSEEAFMGKGVSACATCDGFFYRGQDVAVIGGGNTAVEE
ALYLTGIAKKVTVIHRRDKFRAEPILVDRLLEKQKEGVVDIKWDHVLDEVTGEDSGVTGVRIKHVKTGATEDIAVQGLFV
AIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATATSVPGVFAAGDVQDNVYRQAITSAGTGCMAALDAQRYLESLHDKK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=68.2242990654206, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=34.9358974358974, Blast_Score=141, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=46.6049382716049, Blast_Score=274, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=46.583850931677, Blast_Score=273, Evalue=3e-74,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34198; Mature: 34067

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGV
CCCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QGPELMARFLEHAERFNTEIVFDHIHTAKLHERPIRLIGDSGEYTCDALIIATGASAQYL
CCHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCEEEECCCCCEEEEEEEEEECCCCEEE
GLPSEEAFMGKGVSACATCDGFFYRGQDVAVIGGGNTAVEEALYLTGIAKKVTVIHRRDK
CCCCCHHHHCCCCHHHEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCC
FRAEPILVDRLLEKQKEGVVDIKWDHVLDEVTGEDSGVTGVRIKHVKTGATEDIAVQGLF
CCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEEE
VAIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATATSVPGVFAAGDVQDNVYRQAITSAG
EEECCCCCCCCEECEEEECCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCC
TGCMAALDAQRYLESLHDKK
CCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGV
CCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QGPELMARFLEHAERFNTEIVFDHIHTAKLHERPIRLIGDSGEYTCDALIIATGASAQYL
CCHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCEEEECCCCCEEEEEEEEEECCCCEEE
GLPSEEAFMGKGVSACATCDGFFYRGQDVAVIGGGNTAVEEALYLTGIAKKVTVIHRRDK
CCCCCHHHHCCCCHHHEECCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCC
FRAEPILVDRLLEKQKEGVVDIKWDHVLDEVTGEDSGVTGVRIKHVKTGATEDIAVQGLF
CCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEEE
VAIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATATSVPGVFAAGDVQDNVYRQAITSAG
EEECCCCCCCCEECEEEECCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCC
TGCMAALDAQRYLESLHDKK
CCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]