Click here to switch to the map view.

The map label for this gene is fbp [H]

Identifier: 161525551

GI number: 161525551

Start: 2596253

End: 2597266

Strand: Direct

Name: fbp [H]

Synonym: Bmul_2381

Alternate gene names: 161525551

Gene position: 2596253-2597266 (Clockwise)

Preceding gene: 161525550

Following gene: 161525555

Centisome position: 75.29

GC content: 64.79

Gene sequence:

>1014_bases
ATGTCCATTGCCCGCCGCACCACGCTGTCCAAGTTCCTGATCGAACAGCAGCGCGAGACCAATAACCTCCCCGCCGACCT
GCGCCTGCTGATCGAAGTCGTCGCCCGCGCGTGCAAGGCGATCAGCTACAACGTGTCGAAGGGCGCGCTCGGCGATGCCC
TCGGCACCGCCGGCAGCGAAAACGTCCAGGGCGAAGTGCAGAAGAAGCTCGACATCCTGTCGAACGAGATCCTGCTCGAC
GCGAACGAATGGGGCGGCAACCTCGCCGCGATGGCCTCGGAGGAAATGGAAACGTTCTTCCCGATCCCGGCGAACTATCC
GCGCGGCGAATACCTGCTCGTGTTCGATCCGCTCGACGGCTCGTCGAACATCGACGTGAACGTGTCGATCGGCACGATCT
TCTCGGTGCTGCGCTGCCCGGACGGCAAGCAGGCGACCGAAGAATCGTTCCTGCAGCCCGGCACGCAGCAGGTCGCCGCA
GGCTATGCGGTATACGGCCCGCAGACGGTGTTCGTGCTGACCACCGGCAACGGCGTGAACTGCTTCACGCTCGACCGCGA
AGTCGGCTCGTGGGTGCTCACGCAGAGCAACATGCAGATCCCGGCCGATACGCGCGAATACGCGATCAACGCCTCGAACG
CGCGTCACTGGTACGACCCGGTCAAGCGCTACGTCGACGAACTGAACGCCGGCAAGGACGGCCCGCGCGGCGACAACTTC
AACATGCGCTGGATCGCCTCGATGGTCGCCGACGTGCACCGGATCCTGAACCGCGGCGGGATCTTCATGTATCCGGCCGA
CAAGCGCACGCCGGACCGCCCGGGCAAGCTGCGCCTGATGTACGAGGCGAATCCGATGGCGTTCATCGTCGAGCAGGCAG
GCGGCGCGGCGACCACCGGCACGCAGCGGATCATGGAAGTCCAGCCGACCGGCCTGCACCAGCGCGTGCCGGTGTTCCTC
GGCTCGAAGAACGAAGTCGAACGCGTGACCGCCTATCACCACGAAAGCCAATAA

Upstream 100 bases:

>100_bases
CGCCGCGCGTTGTAACGGGACGAAAAAACCCGTCGGCCGCCGAGGCCCGGCAGGTAAAATTGCGGCAACTCAAGGATTCT
TTGGCCTTTCGGAGTCTGTC

Downstream 100 bases:

>100_bases
TTTGCACCGCAACACTGGACGGACGCGCGCGACGCAAGTAAAATCGCGCCTCGCGATGTGGCCCTGACAGGCCGCATCGC
GGTGAAGTGAAAGCGGGAAG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLD
ANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAA
GYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMAFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFL
GSKNEVERVTAYHHESQ

Sequences:

>Translated_337_residues
MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLD
ANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAA
GYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMAFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFL
GSKNEVERVTAYHHESQ
>Mature_336_residues
SIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLDA
NEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAAG
YAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNFN
MRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMAFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFLG
SKNEVERVTAYHHESQ

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=320, Percent_Identity=42.8125, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI189083692, Length=330, Percent_Identity=42.1212121212121, Blast_Score=251, Evalue=4e-67,
Organism=Homo sapiens, GI16579888, Length=330, Percent_Identity=42.1212121212121, Blast_Score=251, Evalue=4e-67,
Organism=Escherichia coli, GI1790679, Length=330, Percent_Identity=44.8484848484849, Blast_Score=278, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17508131, Length=325, Percent_Identity=43.3846153846154, Blast_Score=273, Evalue=9e-74,
Organism=Saccharomyces cerevisiae, GI6323409, Length=335, Percent_Identity=39.4029850746269, Blast_Score=258, Evalue=9e-70,
Organism=Drosophila melanogaster, GI45550998, Length=325, Percent_Identity=44.9230769230769, Blast_Score=267, Evalue=6e-72,
Organism=Drosophila melanogaster, GI19921562, Length=325, Percent_Identity=44.9230769230769, Blast_Score=267, Evalue=7e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 37162; Mature: 37031

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSE
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCC
NVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDG
CCHHHHHHHHHHHCCEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCCEEEEEECCCC
SSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAAGYAVYGPQTVFVLTTGNGVN
CCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCEEEECCEEEEEEECCCCEE
CFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
EEEECCCCCCEEEECCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMAFIVEQAGGAATTG
CHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCC
TQRIMEVQPTGLHQRVPVFLGSKNEVERVTAYHHESQ
CHHEEEECCCCCCCCCCEEECCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSE
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCC
NVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDG
CCHHHHHHHHHHHCCEEEEECCCCCCCEEEHHHHHHHHEECCCCCCCCCCEEEEEECCCC
SSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTQQVAAGYAVYGPQTVFVLTTGNGVN
CCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHCCEEEECCEEEEEEECCCCEE
CFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYDPVKRYVDELNAGKDGPRGDNF
EEEECCCCCCEEEECCCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
NMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMAFIVEQAGGAATTG
CHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEECCCEEEEEECCCCCCCCC
TQRIMEVQPTGLHQRVPVFLGSKNEVERVTAYHHESQ
CHHEEEECCCCCCCCCCEEECCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA