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The map label for this gene is pepN [H]

Identifier: 161525550

GI number: 161525550

Start: 2593293

End: 2595986

Strand: Direct

Name: pepN [H]

Synonym: Bmul_2380

Alternate gene names: 161525550

Gene position: 2593293-2595986 (Clockwise)

Preceding gene: 161525548

Following gene: 161525551

Centisome position: 75.2

GC content: 68.0

Gene sequence:

>2694_bases
ATGTCCGACAACGCCTCTTCCACCGTGATCCGCCGCGCCGACTACACGCCGCCGGCCTTCCTCATCGATTCCGTCGCGCT
CGAATTCGATCTCGAGCCGGCCCGTACGATCGTCAGGAATACGATGCGCGTGCGTCGCAATCCCGATGCCGCGCCCGCAC
CGCATCTGGAGCTGATGGGCGAGGCGCTCGAATTCCTCGGCGCCCAGCTGAACGGCGCACCGCACGGCGCCGTGCGCGCG
CACGAGCACGGACTGACCGTCGAGAACGTGCCCGACACGTTCGACCTGACGCTCGAAAGCGCGTGCGCGCCCGACCAGAA
CACGACGCTGTCGGGCCTGTACGTATCGAGCGGCAACTTCTTCACGCAATGCGAGGCCGAAGGCTTCCGCCGCATCACGT
ACTTCCTCGATCGTCCCGACGTGATGGCGTCGTATACGGTCGTGCTGCGCGCCGACAAGGCCGCGTATCCGGTGCTGCTG
TCGAACGGCAACCTCGTCGATTCGGGCGACCTGCCCGACGGCCGCCACTTCGCGAAGTGGGAAGACCCGTTCCGCAAGCC
GAGCTATCTGTTCGCGCTGGTCGCAGGCAAGCTCGTCGCGATCGAGGAGCGGATCACGACCGGCTCCGGCAAGGAAAAGC
TGCTGCAGGTCTGGGTCGAGCCGGCCGATCTCGACAAGACGCGTCACGCGATGGATTCGCTGATCCATTCGATCCGCTGG
GACGAACGGCGCTTCGGCCTCGAGCTCGATCTCGACCGCTTCATGATCGTCGCGGTCGGCGACTTCAACATGGGCGCGAT
GGAGAACAAGGGGCTCAACATCTTCAACACGAAGTACGTGCTCGCGAACCCCGAGACGGCGACCGACGTCGATTTCGCGA
ACATCGAATCGGTGGTCGGCCACGAGTATTTCCACAACTGGACCGGCAACCGCGTGACCTGCCGCGACTGGTTCCAGCTG
AGCCTGAAGGAAGGCCTGACGGTGTTCCGCGACCAGGAGTTCTCGGCCGACATGGCCGCCGGCGACGATCTCGAATCGGC
CGCGCGCGCGGTCAAGCGCATCGAGGACGTGCGCGTGCTGCGCCAGCTGCAGTTCGCCGAGGACGCCGGCCCGATGGCGC
ATCCGGTGCGTCCGGAAAGCTACGTCGAGATCAACAACTTCTACACGATGACCGTCTACGAGAAAGGCGCGGAAGTCGTG
CGGATGTATCAGACGCTGTTCGGTCGCGACGGCTTCCGCAAGGGGATGGACCTCTACTTCAAGCGCCACGACGGCCAGGC
CGTCACCTGCGACGATTTCCGTCACGCGATGGCCGATGCAAACGGGCGCGATCTCGCGCAGTTCGAGCGCTGGTACAGCC
AGGCCGGCACGCCGCGCGTGAGCGTGCGCACCGCGTATGACGCGGCCGCGCGCCGCTACACCGTCACGCTCGCGCAGGGC
TACGGCGATGCGTCGCCGGCCGCGCGCGACACGCAGCAGGGTCCGCTGCTGATTCCGTTCGCGATCGGGCTGATCGGCCG
CGACGGCCGCGACCTGCCGCTGCGTCTCGACGGCGAGGCCGCTGCGGCGGGCACGACACGCGTGCTCGAGTTCACAGAGA
CCGAACAGACGTTCACGTTCGTCGACGTGCCCGAAGCGCCGCTGCCGTCGCTGCTGCGCAATTTCTCGGCGCCGGTGATC
GTCGAATACGACTACAGCGACGACGATCTCGCGTTCCTGCTCGCGCACGACAGCGACGCGTTCAATCGCTGGGAAGCCGG
CCAGCGGCTCGCGACGCGCGCGCTGCTGACGCTCGCGTCGCGCGCGGCCGCGAACGAGCCGCTGACGCTCGGCGAGAACT
TCGTCGCCGCGTTCCGCCGCGTGCTGACCGACGCGAACCTGTCGCCGGCGTTCCGCGAACTCGCGCTGACGCTGCCGTCG
GAAACCTACCTCGCCGACCAGATGGCCGAAGCCGATCCGGCCGCCGTGCATCGCGCGCGCCAGTTCGTGCGTCGTCAGCT
CGCGACCGCGCTGCGCGCCGAATGGCTCACCGCGTACGACCAGCACCAGACGCCCGGCACGTACGAGCCGACGCCCGAAG
CGTCGGGCCGCCGCGCGCTGAAGAACCTCGCGCTCGCGTATCTCGCGGAACTCGAGGACCCGGCCGACGCGGTCCGGCTC
GCGACTGCGCAATACGACGCGGCGAACAACATGACCGATCGCGCGGCCGCGCTTGGCGCCCTGCTGTCCGCGGCGGCGGC
CGGCGCGAACGAGCCGGCCGAGCGCGCGCTCGACGACTTCTATCGCCGCTTCGAGAAGGAAGCGCTCGTGATCGACAAGT
GGTTCGCGATGCAAGCCGCGCAACGCGGCACGCCCGCGCAGCCGACGCTCGCGAAGGTCCGCAAGCTGATGGCGCATCCG
GCGTTCAATCTGAAGAATCCGAACCGCGCGCGCTCGCTGATCTTCAGCTTCTGTGCGGCCAACCCCGCGCAGTTCCACGC
GGCGGACGGCTCGGGCTACGCGTTCTGGGCCGAGCAGGTGCTTGCGCTCGACGCGATCAATCCGCAGGTCGCCGCGCGGC
TCGCGCGTTCGCTCGAGCTGTGGCGCCGCTACACGCCCGCGCTGCGCGACAAGATGCGCGAGGCGCTCGAAAAGGTCGCC
GCAGGCGCGAAATCGCGCGACGTGCGCGAGATCGTCGAGAAAGCGCTCGCCTGA

Upstream 100 bases:

>100_bases
AAAAAGTTCGCGCGGCGCGCGGCCGCAAGCCTTTGTACAATGAGCCGGTTCGCCAGGTCCGCGCCGCGGGCCCGATCCCC
TTTCCACGACCTCGACGACC

Downstream 100 bases:

>100_bases
CGCGCGACGCATCGCGGCAGGCGCGCTCGCGCATCGAGGCCGGTACTGCGCCCCGCAGTGCCGGCCTTTTTTCATGAGGC
GCGGCGCGTGCCCGCCGCGC

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 897; Mature: 896

Protein sequence:

>897_residues
MSDNASSTVIRRADYTPPAFLIDSVALEFDLEPARTIVRNTMRVRRNPDAAPAPHLELMGEALEFLGAQLNGAPHGAVRA
HEHGLTVENVPDTFDLTLESACAPDQNTTLSGLYVSSGNFFTQCEAEGFRRITYFLDRPDVMASYTVVLRADKAAYPVLL
SNGNLVDSGDLPDGRHFAKWEDPFRKPSYLFALVAGKLVAIEERITTGSGKEKLLQVWVEPADLDKTRHAMDSLIHSIRW
DERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANIESVVGHEYFHNWTGNRVTCRDWFQL
SLKEGLTVFRDQEFSADMAAGDDLESAARAVKRIEDVRVLRQLQFAEDAGPMAHPVRPESYVEINNFYTMTVYEKGAEVV
RMYQTLFGRDGFRKGMDLYFKRHDGQAVTCDDFRHAMADANGRDLAQFERWYSQAGTPRVSVRTAYDAAARRYTVTLAQG
YGDASPAARDTQQGPLLIPFAIGLIGRDGRDLPLRLDGEAAAAGTTRVLEFTETEQTFTFVDVPEAPLPSLLRNFSAPVI
VEYDYSDDDLAFLLAHDSDAFNRWEAGQRLATRALLTLASRAAANEPLTLGENFVAAFRRVLTDANLSPAFRELALTLPS
ETYLADQMAEADPAAVHRARQFVRRQLATALRAEWLTAYDQHQTPGTYEPTPEASGRRALKNLALAYLAELEDPADAVRL
ATAQYDAANNMTDRAAALGALLSAAAAGANEPAERALDDFYRRFEKEALVIDKWFAMQAAQRGTPAQPTLAKVRKLMAHP
AFNLKNPNRARSLIFSFCAANPAQFHAADGSGYAFWAEQVLALDAINPQVAARLARSLELWRRYTPALRDKMREALEKVA
AGAKSRDVREIVEKALA

Sequences:

>Translated_897_residues
MSDNASSTVIRRADYTPPAFLIDSVALEFDLEPARTIVRNTMRVRRNPDAAPAPHLELMGEALEFLGAQLNGAPHGAVRA
HEHGLTVENVPDTFDLTLESACAPDQNTTLSGLYVSSGNFFTQCEAEGFRRITYFLDRPDVMASYTVVLRADKAAYPVLL
SNGNLVDSGDLPDGRHFAKWEDPFRKPSYLFALVAGKLVAIEERITTGSGKEKLLQVWVEPADLDKTRHAMDSLIHSIRW
DERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANIESVVGHEYFHNWTGNRVTCRDWFQL
SLKEGLTVFRDQEFSADMAAGDDLESAARAVKRIEDVRVLRQLQFAEDAGPMAHPVRPESYVEINNFYTMTVYEKGAEVV
RMYQTLFGRDGFRKGMDLYFKRHDGQAVTCDDFRHAMADANGRDLAQFERWYSQAGTPRVSVRTAYDAAARRYTVTLAQG
YGDASPAARDTQQGPLLIPFAIGLIGRDGRDLPLRLDGEAAAAGTTRVLEFTETEQTFTFVDVPEAPLPSLLRNFSAPVI
VEYDYSDDDLAFLLAHDSDAFNRWEAGQRLATRALLTLASRAAANEPLTLGENFVAAFRRVLTDANLSPAFRELALTLPS
ETYLADQMAEADPAAVHRARQFVRRQLATALRAEWLTAYDQHQTPGTYEPTPEASGRRALKNLALAYLAELEDPADAVRL
ATAQYDAANNMTDRAAALGALLSAAAAGANEPAERALDDFYRRFEKEALVIDKWFAMQAAQRGTPAQPTLAKVRKLMAHP
AFNLKNPNRARSLIFSFCAANPAQFHAADGSGYAFWAEQVLALDAINPQVAARLARSLELWRRYTPALRDKMREALEKVA
AGAKSRDVREIVEKALA
>Mature_896_residues
SDNASSTVIRRADYTPPAFLIDSVALEFDLEPARTIVRNTMRVRRNPDAAPAPHLELMGEALEFLGAQLNGAPHGAVRAH
EHGLTVENVPDTFDLTLESACAPDQNTTLSGLYVSSGNFFTQCEAEGFRRITYFLDRPDVMASYTVVLRADKAAYPVLLS
NGNLVDSGDLPDGRHFAKWEDPFRKPSYLFALVAGKLVAIEERITTGSGKEKLLQVWVEPADLDKTRHAMDSLIHSIRWD
ERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANIESVVGHEYFHNWTGNRVTCRDWFQLS
LKEGLTVFRDQEFSADMAAGDDLESAARAVKRIEDVRVLRQLQFAEDAGPMAHPVRPESYVEINNFYTMTVYEKGAEVVR
MYQTLFGRDGFRKGMDLYFKRHDGQAVTCDDFRHAMADANGRDLAQFERWYSQAGTPRVSVRTAYDAAARRYTVTLAQGY
GDASPAARDTQQGPLLIPFAIGLIGRDGRDLPLRLDGEAAAAGTTRVLEFTETEQTFTFVDVPEAPLPSLLRNFSAPVIV
EYDYSDDDLAFLLAHDSDAFNRWEAGQRLATRALLTLASRAAANEPLTLGENFVAAFRRVLTDANLSPAFRELALTLPSE
TYLADQMAEADPAAVHRARQFVRRQLATALRAEWLTAYDQHQTPGTYEPTPEASGRRALKNLALAYLAELEDPADAVRLA
TAQYDAANNMTDRAAALGALLSAAAAGANEPAERALDDFYRRFEKEALVIDKWFAMQAAQRGTPAQPTLAKVRKLMAHPA
FNLKNPNRARSLIFSFCAANPAQFHAADGSGYAFWAEQVLALDAINPQVAARLARSLELWRRYTPALRDKMREALEKVAA
GAKSRDVREIVEKALA

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=415, Percent_Identity=26.0240963855422, Blast_Score=117, Evalue=5e-26,
Organism=Homo sapiens, GI61742777, Length=333, Percent_Identity=24.024024024024, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI61742775, Length=333, Percent_Identity=24.024024024024, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI132814467, Length=344, Percent_Identity=25, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI310123622, Length=374, Percent_Identity=26.2032085561497, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI310133497, Length=374, Percent_Identity=26.2032085561497, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI194306629, Length=305, Percent_Identity=23.6065573770492, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI11641261, Length=305, Percent_Identity=23.6065573770492, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI94818901, Length=323, Percent_Identity=24.7678018575851, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI94818891, Length=323, Percent_Identity=24.7678018575851, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI157266300, Length=467, Percent_Identity=23.7687366167024, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI7019561, Length=233, Percent_Identity=24.8927038626609, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI4505029, Length=383, Percent_Identity=24.0208877284595, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI40316915, Length=337, Percent_Identity=26.1127596439169, Blast_Score=74, Evalue=8e-13,
Organism=Escherichia coli, GI1787163, Length=889, Percent_Identity=48.2564679415073, Blast_Score=781, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989076, Length=467, Percent_Identity=25.6959314775161, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71989071, Length=458, Percent_Identity=25.9825327510917, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17569225, Length=361, Percent_Identity=26.8698060941828, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17569221, Length=370, Percent_Identity=25.6756756756757, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533276, Length=350, Percent_Identity=26.2857142857143, Blast_Score=101, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533278, Length=350, Percent_Identity=26.2857142857143, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193206928, Length=398, Percent_Identity=25.6281407035176, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI193206926, Length=398, Percent_Identity=25.6281407035176, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI133903840, Length=390, Percent_Identity=21.7948717948718, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71984339, Length=353, Percent_Identity=24.3626062322946, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71984353, Length=353, Percent_Identity=24.3626062322946, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71990873, Length=321, Percent_Identity=23.98753894081, Blast_Score=73, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17565628, Length=308, Percent_Identity=25.974025974026, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI9755335, Length=347, Percent_Identity=26.2247838616715, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321837, Length=407, Percent_Identity=24.5700245700246, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24655257, Length=352, Percent_Identity=28.6931818181818, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24655252, Length=352, Percent_Identity=28.6931818181818, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24655274, Length=352, Percent_Identity=28.6931818181818, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24655260, Length=352, Percent_Identity=28.6931818181818, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24655265, Length=352, Percent_Identity=28.6931818181818, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24655268, Length=352, Percent_Identity=28.6931818181818, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24646514, Length=348, Percent_Identity=28.1609195402299, Blast_Score=120, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24646518, Length=348, Percent_Identity=28.1609195402299, Blast_Score=120, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24646516, Length=348, Percent_Identity=28.1609195402299, Blast_Score=120, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24651025, Length=300, Percent_Identity=28, Blast_Score=100, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24651023, Length=300, Percent_Identity=28, Blast_Score=100, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24651021, Length=300, Percent_Identity=28, Blast_Score=100, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24648786, Length=455, Percent_Identity=26.1538461538462, Blast_Score=100, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24651016, Length=302, Percent_Identity=27.1523178807947, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646512, Length=342, Percent_Identity=23.6842105263158, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646510, Length=342, Percent_Identity=23.6842105263158, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550850, Length=357, Percent_Identity=26.6106442577031, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24650973, Length=357, Percent_Identity=26.6106442577031, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161078673, Length=512, Percent_Identity=24.21875, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571901, Length=512, Percent_Identity=24.21875, Blast_Score=89, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358341, Length=272, Percent_Identity=26.1029411764706, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221379089, Length=353, Percent_Identity=25.7790368271955, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24648790, Length=362, Percent_Identity=24.3093922651934, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571792, Length=375, Percent_Identity=24.2666666666667, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585062, Length=381, Percent_Identity=23.8845144356955, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585064, Length=381, Percent_Identity=23.8845144356955, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585066, Length=381, Percent_Identity=23.8845144356955, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550350, Length=381, Percent_Identity=23.8845144356955, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330574, Length=316, Percent_Identity=25, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 99578; Mature: 99447

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNASSTVIRRADYTPPAFLIDSVALEFDLEPARTIVRNTMRVRRNPDAAPAPHLELMG
CCCCCCCCEEEECCCCCHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
EALEFLGAQLNGAPHGAVRAHEHGLTVENVPDTFDLTLESACAPDQNTTLSGLYVSSGNF
HHHHHHHHHCCCCCCCCCEECCCCCEECCCCCCHHEEEHHCCCCCCCCEEEEEEEECCCE
FTQCEAEGFRRITYFLDRPDVMASYTVVLRADKAAYPVLLSNGNLVDSGDLPDGRHFAKW
EEEECCCCCEEEEEEECCCCHHEEEEEEEEECCCCCCEEECCCCEEECCCCCCCCCCCCC
EDPFRKPSYLFALVAGKLVAIEERITTGSGKEKLLQVWVEPADLDKTRHAMDSLIHSIRW
CCCCCCHHHHHHHHHCHHHEEHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
DERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANIESVVG
CHHHCCCEECCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMAAGDDLESAARAVKRIEDVRVL
HHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RQLQFAEDAGPMAHPVRPESYVEINNFYTMTVYEKGAEVVRMYQTLFGRDGFRKGMDLYF
HHHHHHHCCCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCCCCHHCCCCEEE
KRHDGQAVTCDDFRHAMADANGRDLAQFERWYSQAGTPRVSVRTAYDAAARRYTVTLAQG
EECCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHCEEEEEEECC
YGDASPAARDTQQGPLLIPFAIGLIGRDGRDLPLRLDGEAAAAGTTRVLEFTETEQTFTF
CCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCEEEE
VDVPEAPLPSLLRNFSAPVIVEYDYSDDDLAFLLAHDSDAFNRWEAGQRLATRALLTLAS
EECCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RAAANEPLTLGENFVAAFRRVLTDANLSPAFRELALTLPSETYLADQMAEADPAAVHRAR
HHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
QFVRRQLATALRAEWLTAYDQHQTPGTYEPTPEASGRRALKNLALAYLAELEDPADAVRL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
ATAQYDAANNMTDRAAALGALLSAAAAGANEPAERALDDFYRRFEKEALVIDKWFAMQAA
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHH
QRGTPAQPTLAKVRKLMAHPAFNLKNPNRARSLIFSFCAANPAQFHAADGSGYAFWAEQV
HCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
LALDAINPQVAARLARSLELWRRYTPALRDKMREALEKVAAGAKSRDVREIVEKALA
HHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SDNASSTVIRRADYTPPAFLIDSVALEFDLEPARTIVRNTMRVRRNPDAAPAPHLELMG
CCCCCCCEEEECCCCCHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
EALEFLGAQLNGAPHGAVRAHEHGLTVENVPDTFDLTLESACAPDQNTTLSGLYVSSGNF
HHHHHHHHHCCCCCCCCCEECCCCCEECCCCCCHHEEEHHCCCCCCCCEEEEEEEECCCE
FTQCEAEGFRRITYFLDRPDVMASYTVVLRADKAAYPVLLSNGNLVDSGDLPDGRHFAKW
EEEECCCCCEEEEEEECCCCHHEEEEEEEEECCCCCCEEECCCCEEECCCCCCCCCCCCC
EDPFRKPSYLFALVAGKLVAIEERITTGSGKEKLLQVWVEPADLDKTRHAMDSLIHSIRW
CCCCCCHHHHHHHHHCHHHEEHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
DERRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPETATDVDFANIESVVG
CHHHCCCEECCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMAAGDDLESAARAVKRIEDVRVL
HHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RQLQFAEDAGPMAHPVRPESYVEINNFYTMTVYEKGAEVVRMYQTLFGRDGFRKGMDLYF
HHHHHHHCCCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHCCCCHHCCCCEEE
KRHDGQAVTCDDFRHAMADANGRDLAQFERWYSQAGTPRVSVRTAYDAAARRYTVTLAQG
EECCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHHHCEEEEEEECC
YGDASPAARDTQQGPLLIPFAIGLIGRDGRDLPLRLDGEAAAAGTTRVLEFTETEQTFTF
CCCCCCCCCCCCCCCEEEEEHHHHCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCEEEE
VDVPEAPLPSLLRNFSAPVIVEYDYSDDDLAFLLAHDSDAFNRWEAGQRLATRALLTLAS
EECCCCCHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RAAANEPLTLGENFVAAFRRVLTDANLSPAFRELALTLPSETYLADQMAEADPAAVHRAR
HHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
QFVRRQLATALRAEWLTAYDQHQTPGTYEPTPEASGRRALKNLALAYLAELEDPADAVRL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
ATAQYDAANNMTDRAAALGALLSAAAAGANEPAERALDDFYRRFEKEALVIDKWFAMQAA
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHH
QRGTPAQPTLAKVRKLMAHPAFNLKNPNRARSLIFSFCAANPAQFHAADGSGYAFWAEQV
HCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
LALDAINPQVAARLARSLELWRRYTPALRDKMREALEKVAAGAKSRDVREIVEKALA
HHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]