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The map label for this gene is rnr [H]

Identifier: 161524859

GI number: 161524859

Start: 1854554

End: 1857010

Strand: Reverse

Name: rnr [H]

Synonym: Bmul_1686

Alternate gene names: 161524859

Gene position: 1857010-1854554 (Counterclockwise)

Preceding gene: 161524860

Following gene: 161524858

Centisome position: 53.85

GC content: 67.85

Gene sequence:

>2457_bases
TTGAGCAAATATCCGTACCCCATTCCGAGCCGTGAAGAGATTCTCGGCGTGCTGCGTACGAGCGACGCGCCGCTGGCCGC
CAACGACATCGCGGAAGCGCTGTCGATCAAGCGCCAGGAGCGCGAAGGGTTCTTCCGGCGTGTCGCCGCAATGGAGCGCG
ACGGCCAGATCCGGCTCGACAAGCGTGGCCATTACCAACTGACCCATCCGTCCAATTTCGTGGCCGGCCGCGTGCAGGGC
CATCGCGACGGCTACGGCTTCGTCATTCGCGACGACGGCCAGGACGACCTGTTCCTGCCGAACGGCGAAATGCAGAAGGT
GATGCACAACGATCGCGTGCTCGCACGGATCGTCGGCTACGACCGCCGCGGCCGGCCGGAAGGGCATGTCGTCGAAGTCA
CCGAGCGCGCGAACAAGCGCGTCATCGGCCGTCTGCTGAACGAGAACGGCGCGCTGATCGTTGCGCCCGAAGACAAGCGC
ATCGGCCACGACATCCTGATCACGCAGAACGTCAAGAAGGCGAAGGTCGGGCAGGTGGTCGTCGTCGAGCTGACCGATTT
CCCGAGCCGTCATTCGCAGCCGCTCGGCCGCGTCGTCGAGGTGCTCGGCGACATCGACGACCCGGGCATGGAAATCGAAA
TCGCGGTGCGCAAGTACGGCGTGCCGCACGAATTCAGCGCGGCGGCGCTCGACGAGGCCGCCGCGCTGCCCGACAAGGTG
CGGCCGGCCGATCTGCGGTTCCGTGTCGACCTGCGCGACGTGCCGCTCGTGACGATCGACGGCGAAGACGCGCGCGACTT
CGACGATGCCGTCTACTGCGAGCCGACGAAGGTCGGCCGCGGCGACGGCTTCCGGCTCATCGTCGCGATCGCCGACGTGT
CGCACTACGTCCAGCCGGGCAGCGGGCTCGACGCCGACGCACTGGAACGCAGCACGTCGGTCTACTTCCCGCGCCGCGTG
ATTCCGATGCTGCCGGAGAAGCTGTCGAACGGCCTCTGCTCGCTGAACCCGCAGGTCGACCGCTGCGTGCTCGCATGCGA
CATCGTGATCACCGCGCGCGGCGAGATCAAGGCGTATCAGTTCTATCCGGCCGTGATCCACTCGGCCGCGCGTCTCACGT
ATACGGAAGTCGCGGCGGTGCTCGCCAACACGAAGGGGCCGGAAGCCGCGCGTCGCGCGGAGCTGCTGCCGCACCTGCAG
AACCTGTACGGCGTGTACAAGGCGCTGTTCGCGGCGCGCCAGAAGCGCGGCGCGATCGACTTCGACACGACCGAGACCTA
CATCGTCTGCAACGCGCAGGGCAAGATCGAGCAGATCGTCCCGCGCCAGCGCAACGACGCGCACAAGCTGATCGAGGAAT
GCATGCTGGCCGCGAACGTCTGCGCGGCCGACTTCCTCAAGCGCCACAAGCATCCGGGCCTGTACCGCGTGCACGCGGGG
CCGACGCCGGAGAAGCTCGAGAACCTGCGTGCGTTCCTGCGCGGCATGGGCTTGACGCTCGGCGGCGGCGAGACGCCGCA
CGCGAGCGACTACGCGGCGCTGATGGCGCAGATCCGCGACCGGCCCGACGCGCAGATGCTGCAGCCGATGCTGCTGCGTT
CGATGCAGCAGGCCGTCTACAGCCCCGACAACATCGGTCACTTCGGCCTCGCGTACGACGCCTACGCGCACTTCACGAGC
CCGATTCGCCGCTATCCGGACCTGCTCACGCACCGCGCGATCTACGCGATCCTGTCGGGCAAGAAGTACGTGCCGAAGGC
GCCGGAAGGGTTCGAACTGAACACCGCGCTGTCGCCGCGCGCGCGCGCGATGCAGCAGGCCGACGACGAAGCGCGCAACC
GCTCGCGCAACAACACCGCGATCTGGGAAGAGCTCGGCCTGCACTGCTCGGCGAACGAGCGGCGCGCGGACGAGGCGTCG
CGCGACGTCGAGGCCTGGCTGAAGTGCTATTTCATGCGCGACAAGCTCGGCGAGGAGTACGGCGGGATGGTGAACGGCGT
CACGTCGTTCGGCATCTTCGTGCAGCTCGACACGCTGTTCATCGAAGGGCTCGTGCACGTGACGGAACTCGGCTCCGACT
ACTTCCAGTACGACGAGATCAAGAACGAGCTGCGCGGCGAACGCACGGGCATCCGCTATCGGCTGTCGGACCGCGTGCGC
GTGCAGGTGAGCCGCGTCGATCTCGATGCACGCAAGATCGACTTCCGGCTCGTGCGCGACACGCCGGTGAAGGCGCCGCG
TCCGGTCGTTGCATCGGCACCGGGCGCCGAGCGCGGCGGCCCGCGCGTGCGCGCGCTGCCGCAGGCGGAAGAATCGACGC
CGCATCACAAGAAGGCTGCGAGCGCGCCGAGTGCCGCGGTGAAGGAAGCGCGCGCGGCGCGCGCCGCCGCGAAGAAGAAG
GGCGGCACGGCGGCGAAGGCCCCCGCGAAGAAGGTGCGCGCCCGCAAGAAACACTGA

Upstream 100 bases:

>100_bases
AATGATCCGCCGCCGTCACTATAGAACTGTCTGACGGACACTTCTATGTTGATGCCGTGCACCATCTGTCAACGCAACGA
GAACAATCATCGACAAACCC

Downstream 100 bases:

>100_bases
GCGTGCGGGGCGCAATGCGCTCCGCCGTATCGAAAGACGCCGCGTCGCCGGTCATGTGCCGGCCACGCGGCGCTTTCCTT
TTCCATGGATCGCGGCTGCG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 818; Mature: 817

Protein sequence:

>818_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKR
IGHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSAAALDEAAALPDKV
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGFRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLACDIVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLANTKGPEAARRAELLPHLQ
NLYGVYKALFAARQKRGAIDFDTTETYIVCNAQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRHKHPGLYRVHAG
PTPEKLENLRAFLRGMGLTLGGGETPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTS
PIRRYPDLLTHRAIYAILSGKKYVPKAPEGFELNTALSPRARAMQQADDEARNRSRNNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKAPRPVVASAPGAERGGPRVRALPQAEESTPHHKKAASAPSAAVKEARAARAAAKKK
GGTAAKAPAKKVRARKKH

Sequences:

>Translated_818_residues
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQG
HRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKR
IGHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSAAALDEAAALPDKV
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGFRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRV
IPMLPEKLSNGLCSLNPQVDRCVLACDIVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLANTKGPEAARRAELLPHLQ
NLYGVYKALFAARQKRGAIDFDTTETYIVCNAQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRHKHPGLYRVHAG
PTPEKLENLRAFLRGMGLTLGGGETPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTS
PIRRYPDLLTHRAIYAILSGKKYVPKAPEGFELNTALSPRARAMQQADDEARNRSRNNTAIWEELGLHCSANERRADEAS
RDVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
VQVSRVDLDARKIDFRLVRDTPVKAPRPVVASAPGAERGGPRVRALPQAEESTPHHKKAASAPSAAVKEARAARAAAKKK
GGTAAKAPAKKVRARKKH
>Mature_817_residues
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLDKRGHYQLTHPSNFVAGRVQGH
RDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGYDRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRI
GHDILITQNVKKAKVGQVVVVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSAAALDEAAALPDKVR
PADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGFRLIVAIADVSHYVQPGSGLDADALERSTSVYFPRRVI
PMLPEKLSNGLCSLNPQVDRCVLACDIVITARGEIKAYQFYPAVIHSAARLTYTEVAAVLANTKGPEAARRAELLPHLQN
LYGVYKALFAARQKRGAIDFDTTETYIVCNAQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRHKHPGLYRVHAGP
TPEKLENLRAFLRGMGLTLGGGETPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVYSPDNIGHFGLAYDAYAHFTSP
IRRYPDLLTHRAIYAILSGKKYVPKAPEGFELNTALSPRARAMQQADDEARNRSRNNTAIWEELGLHCSANERRADEASR
DVEAWLKCYFMRDKLGEEYGGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVRV
QVSRVDLDARKIDFRLVRDTPVKAPRPVVASAPGAERGGPRVRALPQAEESTPHHKKAASAPSAAVKEARAARAAAKKKG
GTAAKAPAKKVRARKKH

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=487, Percent_Identity=28.952772073922, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI190014623, Length=487, Percent_Identity=28.952772073922, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI134288890, Length=446, Percent_Identity=30.7174887892377, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI19115966, Length=500, Percent_Identity=29, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI219521928, Length=500, Percent_Identity=29, Blast_Score=159, Evalue=9e-39,
Organism=Escherichia coli, GI87082383, Length=756, Percent_Identity=48.1481481481481, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=698, Percent_Identity=27.2206303724928, Blast_Score=200, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI212645896, Length=416, Percent_Identity=30.7692307692308, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17553506, Length=531, Percent_Identity=28.6252354048964, Blast_Score=164, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324552, Length=654, Percent_Identity=25.9938837920489, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24649634, Length=468, Percent_Identity=29.2735042735043, Blast_Score=186, Evalue=7e-47,
Organism=Drosophila melanogaster, GI19922976, Length=434, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24654597, Length=434, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24654592, Length=434, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 90990; Mature: 90859

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCCHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRIGHDILITQNVKKAKVGQVV
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHCCCCEE
VVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSAAALDEAAALPDKV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCC
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGFRLIVAIADVSHYVQPG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEEECHHHHCCCC
SGLDADALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLACDIVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCCHHHEEEEEEEEEEECCCEEEEE
FYPAVIHSAARLTYTEVAAVLANTKGPEAARRAELLPHLQNLYGVYKALFAARQKRGAID
EEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNAQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRHKHPGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
PTPEKLENLRAFLRGMGLTLGGGETPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYDAYAHFTSPIRRYPDLLTHRAIYAILSGKKYVPKAPEGFELNTALSPR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHH
ARAMQQADDEARNRSRNNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHCHHHHEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKAPRPVVASAPGAERGGPRVRALPQAEESTPHHKKAA
EEEEEECCCCCEEEEEEEECCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCHHHHC
SAPSAAVKEARAARAAAKKKGGTAAKAPAKKVRARKKH
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SKYPYPIPSREEILGVLRTSDAPLAANDIAEALSIKRQEREGFFRRVAAMERDGQIRLD
CCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
KRGHYQLTHPSNFVAGRVQGHRDGYGFVIRDDGQDDLFLPNGEMQKVMHNDRVLARIVGY
CCCCEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEECCCCHHHHHHHCCHHHHHHHCC
DRRGRPEGHVVEVTERANKRVIGRLLNENGALIVAPEDKRIGHDILITQNVKKAKVGQVV
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHCCCCEE
VVELTDFPSRHSQPLGRVVEVLGDIDDPGMEIEIAVRKYGVPHEFSAAALDEAAALPDKV
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCC
RPADLRFRVDLRDVPLVTIDGEDARDFDDAVYCEPTKVGRGDGFRLIVAIADVSHYVQPG
CCCCEEEEEEECCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEEEECHHHHCCCC
SGLDADALERSTSVYFPRRVIPMLPEKLSNGLCSLNPQVDRCVLACDIVITARGEIKAYQ
CCCCHHHHHCCCCCCCCHHHHHHCHHHHCCCCCCCCCCHHHEEEEEEEEEEECCCEEEEE
FYPAVIHSAARLTYTEVAAVLANTKGPEAARRAELLPHLQNLYGVYKALFAARQKRGAID
EEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDTTETYIVCNAQGKIEQIVPRQRNDAHKLIEECMLAANVCAADFLKRHKHPGLYRVHAG
CCCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
PTPEKLENLRAFLRGMGLTLGGGETPHASDYAALMAQIRDRPDAQMLQPMLLRSMQQAVY
CCHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
SPDNIGHFGLAYDAYAHFTSPIRRYPDLLTHRAIYAILSGKKYVPKAPEGFELNTALSPR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCHH
ARAMQQADDEARNRSRNNTAIWEELGLHCSANERRADEASRDVEAWLKCYFMRDKLGEEY
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
GGMVNGVTSFGIFVQLDTLFIEGLVHVTELGSDYFQYDEIKNELRGERTGIRYRLSDRVR
CCHHHCHHHHEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCEE
VQVSRVDLDARKIDFRLVRDTPVKAPRPVVASAPGAERGGPRVRALPQAEESTPHHKKAA
EEEEEECCCCCEEEEEEEECCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCHHHHC
SAPSAAVKEARAARAAAKKKGGTAAKAPAKKVRARKKH
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]