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The map label for this gene is tas [H]

Identifier: 161524822

GI number: 161524822

Start: 1825460

End: 1826512

Strand: Reverse

Name: tas [H]

Synonym: Bmul_1649

Alternate gene names: 161524822

Gene position: 1826512-1825460 (Counterclockwise)

Preceding gene: 161524823

Following gene: 161524819

Centisome position: 52.97

GC content: 66.1

Gene sequence:

>1053_bases
ATGGAATACCGCACACTCGGCGATTCGGGCATCGAGGTGAGCCTGATCGGTCTCGGCACGATGACGTGGGGCGAGCAGAA
TTCGGAGCGCGATGCGCACGAGCAGATCGATTACGCGCTCGACCATGGCGTCACGCTGATCGACGCCGCGGAGATGTATC
CGGTGCCGCCGAAGCCCGATACGCAGGGGCGCACCGAACAGTACATCGGCACGTGGCTCGCGCAGCATCGCGCGCAGCGC
GACCGGATCGTGCTCGCGACGAAGATCGCGGGGCCGGCACGGCAACCGCACAACCCGCGGCATATTCGCGGCGAGGGCAA
CCAGTTCGACCGCAAGAATCTGACCGAAGCGCTCGACGGCAGCCTGAAACGGCTGCAGACCGACTACGTCGATCTCTATC
AGCTGCATTGGCCCGATCGCAGCACGACGACGTTCGGCCGCTCCGCGTATCCGTGGATCGACGACGCGTATACGGTGCCG
ATCGAAGAAACGCTCGCGGTACTCGCCGAATTCGTGAAGGCCGGCAAGGTGCGCGCGATCGGCGTGTCGAACGAAACGCC
GTGGGGCGTCGCGCAATTCCTGCGCGCGGCCGAGAAGCTCGGGCTGCCGCGCATCGCGAGCATCCAGAATCCGTATAGCC
TGCTGAACCGCACGTTCGAGAACGGCTTGTCGGAATTCACGCATCGCGAGGGTGTCGGCCTGCTCGCCTATTCGCCGCTC
GCGTTCGGCTGGCTGTCCGGCAAGTACGAGAACGGCGCGCGTCCGGCCGGCGCACGCATCACGCTGTTCGAACGCTTCCA
GCGCTACAGCAAGCCGCAGGCCGTCGCGGCGACGTCGCGCTACGTCGCGCTCGCGAAGCGGCACGGCCTGTCGCCCGCGC
AGCTCGCGCTCGCGTTCGTGAACAGCCGTCCGTTCGTGCGCAGCAATCTGATCGGCGCGACGTCGCTCGACCAGCTGAAG
GAGAACATCGGCAGCATCGACGTGAAGCTGTCCGACGAGATTCTCGCGGAGATCGACGCGCTGCACGAGCAGCAGCCGAA
CCCGGCGCCGTAA

Upstream 100 bases:

>100_bases
CGGCTATCGAAGGCGCAATGTAAGCTGCGGCGGCGCGCGTCTGAAGCGTTCGTTTCAATGTGATAGCGTTCCTGCTTTCC
ACCGACGCGACAGGAACAGC

Downstream 100 bases:

>100_bases
ACGACGTGCGGCCCGCGCGGCGCGATGCCGGCGCGGGCCGTTTTCCATCGGCAGCGCATCGCGCTGCCGTTTCCGCTATT
GCATCCGCAGCCGCGTACGT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALDHGVTLIDAAEMYPVPPKPDTQGRTEQYIGTWLAQHRAQR
DRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDGSLKRLQTDYVDLYQLHWPDRSTTTFGRSAYPWIDDAYTVP
IEETLAVLAEFVKAGKVRAIGVSNETPWGVAQFLRAAEKLGLPRIASIQNPYSLLNRTFENGLSEFTHREGVGLLAYSPL
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVAATSRYVALAKRHGLSPAQLALAFVNSRPFVRSNLIGATSLDQLK
ENIGSIDVKLSDEILAEIDALHEQQPNPAP

Sequences:

>Translated_350_residues
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALDHGVTLIDAAEMYPVPPKPDTQGRTEQYIGTWLAQHRAQR
DRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDGSLKRLQTDYVDLYQLHWPDRSTTTFGRSAYPWIDDAYTVP
IEETLAVLAEFVKAGKVRAIGVSNETPWGVAQFLRAAEKLGLPRIASIQNPYSLLNRTFENGLSEFTHREGVGLLAYSPL
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVAATSRYVALAKRHGLSPAQLALAFVNSRPFVRSNLIGATSLDQLK
ENIGSIDVKLSDEILAEIDALHEQQPNPAP
>Mature_350_residues
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALDHGVTLIDAAEMYPVPPKPDTQGRTEQYIGTWLAQHRAQR
DRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDGSLKRLQTDYVDLYQLHWPDRSTTTFGRSAYPWIDDAYTVP
IEETLAVLAEFVKAGKVRAIGVSNETPWGVAQFLRAAEKLGLPRIASIQNPYSLLNRTFENGLSEFTHREGVGLLAYSPL
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVAATSRYVALAKRHGLSPAQLALAFVNSRPFVRSNLIGATSLDQLK
ENIGSIDVKLSDEILAEIDALHEQQPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=360, Percent_Identity=32.2222222222222, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI4504825, Length=358, Percent_Identity=32.122905027933, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI27436964, Length=360, Percent_Identity=30.8333333333333, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI27436962, Length=360, Percent_Identity=30.8333333333333, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI27436966, Length=360, Percent_Identity=30.5555555555556, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI27436971, Length=362, Percent_Identity=30.939226519337, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI41327764, Length=328, Percent_Identity=26.5243902439024, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI41152114, Length=247, Percent_Identity=28.3400809716599, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI223718702, Length=222, Percent_Identity=30.1801801801802, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=58.2857142857143, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI87081735, Length=356, Percent_Identity=29.4943820224719, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789375, Length=348, Percent_Identity=31.6091954022989, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788070, Length=343, Percent_Identity=30.3206997084548, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788081, Length=356, Percent_Identity=27.5280898876405, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=355, Percent_Identity=25.9154929577465, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=345, Percent_Identity=26.9565217391304, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=321, Percent_Identity=25.5451713395639, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=338, Percent_Identity=25.7396449704142, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=269, Percent_Identity=25.2788104089219, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324694, Length=248, Percent_Identity=29.4354838709677, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320576, Length=311, Percent_Identity=26.6881028938907, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320079, Length=235, Percent_Identity=30.6382978723404, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24646159, Length=334, Percent_Identity=27.8443113772455, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24646155, Length=343, Percent_Identity=27.9883381924198, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24644950, Length=343, Percent_Identity=24.7813411078717, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38917; Mature: 38917

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALDHGVTLIDAAEMYPVPPKPD
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEHHHHCCCCCCCC
TQGRTEQYIGTWLAQHRAQRDRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDG
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHH
SLKRLQTDYVDLYQLHWPDRSTTTFGRSAYPWIDDAYTVPIEETLAVLAEFVKAGKVRAI
HHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLRAAEKLGLPRIASIQNPYSLLNRTFENGLSEFTHREGVGLLAYSPL
ECCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVAATSRYVALAKRHGLSPAQLALAFV
HHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFVRSNLIGATSLDQLKENIGSIDVKLSDEILAEIDALHEQQPNPAP
CCCCCHHHCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEYRTLGDSGIEVSLIGLGTMTWGEQNSERDAHEQIDYALDHGVTLIDAAEMYPVPPKPD
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEHHHHCCCCCCCC
TQGRTEQYIGTWLAQHRAQRDRIVLATKIAGPARQPHNPRHIRGEGNQFDRKNLTEALDG
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCHHHHHHHHHH
SLKRLQTDYVDLYQLHWPDRSTTTFGRSAYPWIDDAYTVPIEETLAVLAEFVKAGKVRAI
HHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLRAAEKLGLPRIASIQNPYSLLNRTFENGLSEFTHREGVGLLAYSPL
ECCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCH
AFGWLSGKYENGARPAGARITLFERFQRYSKPQAVAATSRYVALAKRHGLSPAQLALAFV
HHHHHCCCCCCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFVRSNLIGATSLDQLKENIGSIDVKLSDEILAEIDALHEQQPNPAP
CCCCCHHHCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]