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The map label for this gene is cobK [H]

Identifier: 161524738

GI number: 161524738

Start: 1715378

End: 1716109

Strand: Reverse

Name: cobK [H]

Synonym: Bmul_1565

Alternate gene names: 161524738

Gene position: 1716109-1715378 (Counterclockwise)

Preceding gene: 161524739

Following gene: 161524737

Centisome position: 49.76

GC content: 74.59

Gene sequence:

>732_bases
ATGAGCGCGCGCATCCTGCTGCTCGGCGGCACCGGCGACGCACTGACGATCGCGCGCGCGCTCGGCCCACAGCACGTCTA
CAGCCTCGCGGGGCTCGGCAAGGTGCCGGACGATCTGCGCTGCGCGGTACGCGTCGGCGGCTTCGGCGGCGCGGCGGCGC
TTGGCGCGTATCTGCGCGCCGAGCGGATCGGCCTCGTGATCGACGCGACACATCCGTATGCCGCGCGGATCAGCGCGAAC
GCGGCCGCCGCCGCGCGCGACGCCGGCGTGCCGCTGTGGGCACTGCGCCGCGCGCCGTGGACGCCGCAAGCCGGCGACGA
TTGGCGCATGGTCGACGACTGGGCCGGCATCGAGGCCGCGATCGCGCCGTTCCGCCGGCCGCTGTTCACGCTCGGTCGCG
AACCGCTCGCGCATCTCGACGCGATCCCGCCGCACCAGTTCTGGCTCGTGCGCTGCCTCGATGCGCATCCGGGCAACGCG
CGCGCACAGGTCGTCGCCGCACGCGGGCCATTCACGCTCGACGGCGAACGCGCGCTGTTCGCGCTCGCGGGGATCGACGT
CGTCGTCAGCAAGAACAGCGGCGGCAGCGCGACCGAAGCGAAGCTCGAGGTCGCGCGCGAGCGCAGGCTGCCGGTCGTGA
TGCTGCGCCGGCCGACCCTGCCCGATGCCGATCGCACGTTCGAGTCGGCCGCCGCGCTGCTCGCAGCGCTCGATCCGGCC
GCGCGCGCGTGA

Upstream 100 bases:

>100_bases
GTGCGCATGCGCTGCGCGTCGCGCGCGACATCGTGCCCGCGTCGGTCGCCGTCGAGATGTTCGCGATCGACCGGCAGGGC
CGTTTCGTCGGGAGCGCACG

Downstream 100 bases:

>100_bases
GACGCGGCGCATCGCCCCATCCACTGACGGAGTTTTTTCGATGACGGTGTATTTCATCGGCGCGGGTCCCGGCGACCCGG
AGCTGATCACGGTGAAGGGC

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSARILLLGGTGDALTIARALGPQHVYSLAGLGKVPDDLRCAVRVGGFGGAAALGAYLRAERIGLVIDATHPYAARISAN
AAAAARDAGVPLWALRRAPWTPQAGDDWRMVDDWAGIEAAIAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNA
RAQVVAARGPFTLDGERALFALAGIDVVVSKNSGGSATEAKLEVARERRLPVVMLRRPTLPDADRTFESAAALLAALDPA
ARA

Sequences:

>Translated_243_residues
MSARILLLGGTGDALTIARALGPQHVYSLAGLGKVPDDLRCAVRVGGFGGAAALGAYLRAERIGLVIDATHPYAARISAN
AAAAARDAGVPLWALRRAPWTPQAGDDWRMVDDWAGIEAAIAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNA
RAQVVAARGPFTLDGERALFALAGIDVVVSKNSGGSATEAKLEVARERRLPVVMLRRPTLPDADRTFESAAALLAALDPA
ARA
>Mature_242_residues
SARILLLGGTGDALTIARALGPQHVYSLAGLGKVPDDLRCAVRVGGFGGAAALGAYLRAERIGLVIDATHPYAARISANA
AAAARDAGVPLWALRRAPWTPQAGDDWRMVDDWAGIEAAIAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNAR
AQVVAARGPFTLDGERALFALAGIDVVVSKNSGGSATEAKLEVARERRLPVVMLRRPTLPDADRTFESAAALLAALDPAA
RA

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 25639; Mature: 25508

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARILLLGGTGDALTIARALGPQHVYSLAGLGKVPDDLRCAVRVGGFGGAAALGAYLRA
CCCEEEEEECCCCHHHHHHHHCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
ERIGLVIDATHPYAARISANAAAAARDAGVPLWALRRAPWTPQAGDDWRMVDDWAGIEAA
HHEEEEEECCCCCEEEECCCHHHHHHCCCCCEEECCCCCCCCCCCCCCEEEHHHCCHHHH
IAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNARAQVVAARGPFTLDGERALF
HHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCEEECCCCEEE
ALAGIDVVVSKNSGGSATEAKLEVARERRLPVVMLRRPTLPDADRTFESAAALLAALDPA
EEECEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHH
ARA
HCC
>Mature Secondary Structure 
SARILLLGGTGDALTIARALGPQHVYSLAGLGKVPDDLRCAVRVGGFGGAAALGAYLRA
CCEEEEEECCCCHHHHHHHHCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
ERIGLVIDATHPYAARISANAAAAARDAGVPLWALRRAPWTPQAGDDWRMVDDWAGIEAA
HHEEEEEECCCCCEEEECCCHHHHHHCCCCCEEECCCCCCCCCCCCCCEEEHHHCCHHHH
IAPFRRPLFTLGREPLAHLDAIPPHQFWLVRCLDAHPGNARAQVVAARGPFTLDGERALF
HHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCEEECCCCEEE
ALAGIDVVVSKNSGGSATEAKLEVARERRLPVVMLRRPTLPDADRTFESAAALLAALDPA
EEECEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHH
ARA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]