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The map label for this gene is blh [H]

Identifier: 161524688

GI number: 161524688

Start: 1667650

End: 1668534

Strand: Reverse

Name: blh [H]

Synonym: Bmul_1515

Alternate gene names: 161524688

Gene position: 1668534-1667650 (Counterclockwise)

Preceding gene: 161524690

Following gene: 161524687

Centisome position: 48.38

GC content: 69.27

Gene sequence:

>885_bases
GTGACGCACTCTGCCGGCCTGGCGGTCGAAGGCTTTTTCGACCCGGCGACCCACACCGTCAGCTATCTGCTGCTCGACAC
CGCGACGCGCGCCTGTGCGCTGATCGACAGCGTGCTCGATTACGACCCGAAGTCCGGCCGCACGCGCACGGACAGCGCCG
ATCGGCTGATCGCGCGCGTCGCCAAGCTCGGCGCGACCGTCCATTGGCTGCTCGAGACGCATGTGCATGCCGATCACCTG
TCGGCCGCGCCGTACCTGAAGGCGCGCGTCGGCGGGCGGATCGCGATCGGCGCGCAGGTGCGGCGCGTGCAGCACGTGTT
CGGCGACCTCTTCAATGCGGGCCTCGGCTTCGCGCGCGACGGCAGCCAGTTCGACAGGCTGCTCGACGACGGCGACACGC
TCGTACTCGGCACGCTGACGATCCGCGCGCTGCACACGCCCGGCCATACGCCCGCATGCATGACCTACTGCGTCGACGAC
GCGACGCAGCGTGCGGCATTCGTCGGCGATACGCTCTTCATGCCCGACTACGGCACCGCCCGCTGCGATTTTCCGGGCGG
CGATGCGCGCACGCTGTACCGCTCGATCGCGCGCGTGCTCGCGCTGCCGCCCGACACGCGGCTCTATCTGTGCCACGACT
ACCAGCCGGGCGGACGCGACGTGCAGTTCGTGACGACCGTCGCCGAGCAGCGCCGCGCGAACGTGCACGTGAAGGACGGC
GTGACCGAGGACGACTTCGTCGCGATGCGCACCGCGCGCGACGCGACGCTCGAGATGCCGGTGCTGATGCTGCCGTCCGT
GCAGGTCAACATGCGCGCCGGCCATCTGCCCGAACCCGAAAACAACGGCGTGCGCTATCTGAAGATCCCACTCGACGCGA
TCTGA

Upstream 100 bases:

>100_bases
AATCAAGGACCTGCTTGGACGGCGAGCGCCGCCCTGCTCGCTGGCACGGTTCTTGAGCCATGGATCGCCGTTGCTCCATC
CACCGTTCGAGGACATTCCC

Downstream 100 bases:

>100_bases
GAGCCGACCCGCCCTTCAAACGAGAACCCCGACATGACTCTTCGCACGCTGACCGACACGCTCGCCGTGTCGCCGCAGAT
TGCCGTGGCCGACCTGCCTG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTHSAGLAVEGFFDPATHTVSYLLLDTATRACALIDSVLDYDPKSGRTRTDSADRLIARVAKLGATVHWLLETHVHADHL
SAAPYLKARVGGRIAIGAQVRRVQHVFGDLFNAGLGFARDGSQFDRLLDDGDTLVLGTLTIRALHTPGHTPACMTYCVDD
ATQRAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIARVLALPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDG
VTEDDFVAMRTARDATLEMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI

Sequences:

>Translated_294_residues
MTHSAGLAVEGFFDPATHTVSYLLLDTATRACALIDSVLDYDPKSGRTRTDSADRLIARVAKLGATVHWLLETHVHADHL
SAAPYLKARVGGRIAIGAQVRRVQHVFGDLFNAGLGFARDGSQFDRLLDDGDTLVLGTLTIRALHTPGHTPACMTYCVDD
ATQRAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIARVLALPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDG
VTEDDFVAMRTARDATLEMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI
>Mature_293_residues
THSAGLAVEGFFDPATHTVSYLLLDTATRACALIDSVLDYDPKSGRTRTDSADRLIARVAKLGATVHWLLETHVHADHLS
AAPYLKARVGGRIAIGAQVRRVQHVFGDLFNAGLGFARDGSQFDRLLDDGDTLVLGTLTIRALHTPGHTPACMTYCVDDA
TQRAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIARVLALPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDGV
TEDDFVAMRTARDATLEMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=271, Percent_Identity=29.520295202952, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1787158, Length=226, Percent_Identity=28.3185840707965, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538952, Length=263, Percent_Identity=26.9961977186312, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221330176, Length=264, Percent_Identity=31.0606060606061, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32141; Mature: 32010

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSAGLAVEGFFDPATHTVSYLLLDTATRACALIDSVLDYDPKSGRTRTDSADRLIARV
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
AKLGATVHWLLETHVHADHLSAAPYLKARVGGRIAIGAQVRRVQHVFGDLFNAGLGFARD
HHHCCHHEEHHHHHHCHHHHCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCC
GSQFDRLLDDGDTLVLGTLTIRALHTPGHTPACMTYCVDDATQRAAFVGDTLFMPDYGTA
CHHHHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCE
RCDFPGGDARTLYRSIARVLALPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDG
ECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEECC
VTEDDFVAMRTARDATLEMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI
CCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
THSAGLAVEGFFDPATHTVSYLLLDTATRACALIDSVLDYDPKSGRTRTDSADRLIARV
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
AKLGATVHWLLETHVHADHLSAAPYLKARVGGRIAIGAQVRRVQHVFGDLFNAGLGFARD
HHHCCHHEEHHHHHHCHHHHCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCC
GSQFDRLLDDGDTLVLGTLTIRALHTPGHTPACMTYCVDDATQRAAFVGDTLFMPDYGTA
CHHHHHHHCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCE
RCDFPGGDARTLYRSIARVLALPPDTRLYLCHDYQPGGRDVQFVTTVAEQRRANVHVKDG
ECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEECC
VTEDDFVAMRTARDATLEMPVLMLPSVQVNMRAGHLPEPENNGVRYLKIPLDAI
CCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]