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The map label for this gene is blh [H]

Identifier: 161524687

GI number: 161524687

Start: 1665949

End: 1667616

Strand: Reverse

Name: blh [H]

Synonym: Bmul_1514

Alternate gene names: 161524687

Gene position: 1667616-1665949 (Counterclockwise)

Preceding gene: 161524688

Following gene: 161524686

Centisome position: 48.36

GC content: 72.3

Gene sequence:

>1668_bases
ATGACTCTTCGCACGCTGACCGACACGCTCGCCGTGTCGCCGCAGATTGCCGTGGCCGACCTGCCTGCGCTACATGCCGC
CGGCATCCGCACGATCGTCTGCAACCGTCCGGACCGCGAAAGCGCCGACCAGCCCGACCTCGCCGAGATCCGCGCGGCCG
CCGCGCCGCTCGGCATCGCGGTCCACCATCTGCCGGTCGAACCGGGCAGGATCACCGACGACCACGTCGCGCAGTTCCGC
GCGCTGCTCGCGTCGGCCGTCGGCCCGACGCTCGCCTACTGCCGCACCGGCACGCGCTCGGCGACGCTATGGGCGCTGTC
GCAGGCAGGCCGCATGCGCGCCGACGACATCGTCGCGACGGCCGCCGCGGCCGGCTACGACCTCGCGGCGCTCGCGCCGC
GGCTTGCAGCCGGGAGCGCAGACGCGACGCGCGCGCCCGACGCGCGCCACGAGATCGTGATCGTCGGCGCCGGTGCGGCA
GGCATCGCGGTCGCCTCGAGCTTGCTTGCGCGCGAGCGCACGCTCGACATCGCGATCGTCGATCCGGCCGACGTCCACTA
CTACCAGCCGGGCTGGACGATGGTCGGCGCGGGCGTTTTCGAGGCCGGCACGACTGCGCGCGCGATCGCCGACGTGCTGC
CGCGCGGCGTGCAGCGCATCCGTGCGGCGGTCGCCGCGTTCGAACCCGACGCGCATGCGGTCGTGCTCGACGACGGCCGG
CGCATCGGCTACGGCAAACTCATCGTCTGTGCGGGGCTCAAGCTCGACTGGCAGGCGATCGACGGTCTCGCCGACACGCT
CGGCCGCCACGGCGTCACGTCGAACTACCGCTACGACCTCGCGCCATACACGTGGCAGCTCGTGCAGGCATTTCGCGGCG
GCAACGCGCTGTTCACGCAGCCGCCGATGCCGATCAAGTGCGCGGGCGCGCCGCAGAAGGCGATGTATCTGTCCTGCGAT
CACTGGCAGCGCACGGGACGTCTGGGCGCCGCCCACGTCGAGTTCCTCAATGCCGGCAACGCGCTGTTCGGCGTCGCCGA
CTACGTGCCCGCGCTGATGGCGTATGTGAAACGCTACGGGATCGCGCTGTCGTTCGGCCACAACCTCGTCGCGATCGACG
GCCCCGCGCGCCGCGCGACGTTCGTGCGCACACTGCCCGACGGCGGCACCGAAACGGTCGTCCGCGCGTTCGACATGATC
CACGTCGTGCCGCCGCAGAAGGCACCCGATTTCGTGCGCACGAGCGCGCTCGCGGACGCCGCCGGCTGGGTCGACGTCGA
TCCGGCGACGCTGCGCCACCGCCGCTACGCGGACATCTTCGCGCTCGGCGACGTGACCAACACGACGAACGCGAAGACCG
CGGCGGCCGCGCGCAAGCAGGCGCCCGTCGTCGCGCACAACGTGCTCGCATCGCTCGGCCGCGCGGCCGGCGAAGCGGCC
TACGACGGCTACGGCTCGTGCCCGCTGACGGTCGAACGCGGCAAGATCGTGCTCGCCGAATTCCTGTACGGCGGCAAGGT
CGCGCCGACCTTCCCCGCCTGGCTGCTCGACGGCCGGCGCCCGTCGCGGCTCGCCTGGCTGCTGAAGGCGCGCGTGCTGC
CGCCGCTGTACTGGGACGCGATGCTGAAGGGCCGCGAATGGCTCGCGCAGCCCGCGATCGTGCGCTAA

Upstream 100 bases:

>100_bases
CGGCCATCTGCCCGAACCCGAAAACAACGGCGTGCGCTATCTGAAGATCCCACTCGACGCGATCTGAGAGCCGACCCGCC
CTTCAAACGAGAACCCCGAC

Downstream 100 bases:

>100_bases
GCGCCGCGCGTTCGACGGAATCCGATCATGCTGGTTTCTCTCCTACTCGGCGGCTGCGTCGGCGCGGTGCTCGGTCTGAC
CGGCGCCGGCGGCGGCATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MTLRTLTDTLAVSPQIAVADLPALHAAGIRTIVCNRPDRESADQPDLAEIRAAAAPLGIAVHHLPVEPGRITDDHVAQFR
ALLASAVGPTLAYCRTGTRSATLWALSQAGRMRADDIVATAAAAGYDLAALAPRLAAGSADATRAPDARHEIVIVGAGAA
GIAVASSLLARERTLDIAIVDPADVHYYQPGWTMVGAGVFEAGTTARAIADVLPRGVQRIRAAVAAFEPDAHAVVLDDGR
RIGYGKLIVCAGLKLDWQAIDGLADTLGRHGVTSNYRYDLAPYTWQLVQAFRGGNALFTQPPMPIKCAGAPQKAMYLSCD
HWQRTGRLGAAHVEFLNAGNALFGVADYVPALMAYVKRYGIALSFGHNLVAIDGPARRATFVRTLPDGGTETVVRAFDMI
HVVPPQKAPDFVRTSALADAAGWVDVDPATLRHRRYADIFALGDVTNTTNAKTAAAARKQAPVVAHNVLASLGRAAGEAA
YDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLLDGRRPSRLAWLLKARVLPPLYWDAMLKGREWLAQPAIVR

Sequences:

>Translated_555_residues
MTLRTLTDTLAVSPQIAVADLPALHAAGIRTIVCNRPDRESADQPDLAEIRAAAAPLGIAVHHLPVEPGRITDDHVAQFR
ALLASAVGPTLAYCRTGTRSATLWALSQAGRMRADDIVATAAAAGYDLAALAPRLAAGSADATRAPDARHEIVIVGAGAA
GIAVASSLLARERTLDIAIVDPADVHYYQPGWTMVGAGVFEAGTTARAIADVLPRGVQRIRAAVAAFEPDAHAVVLDDGR
RIGYGKLIVCAGLKLDWQAIDGLADTLGRHGVTSNYRYDLAPYTWQLVQAFRGGNALFTQPPMPIKCAGAPQKAMYLSCD
HWQRTGRLGAAHVEFLNAGNALFGVADYVPALMAYVKRYGIALSFGHNLVAIDGPARRATFVRTLPDGGTETVVRAFDMI
HVVPPQKAPDFVRTSALADAAGWVDVDPATLRHRRYADIFALGDVTNTTNAKTAAAARKQAPVVAHNVLASLGRAAGEAA
YDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLLDGRRPSRLAWLLKARVLPPLYWDAMLKGREWLAQPAIVR
>Mature_554_residues
TLRTLTDTLAVSPQIAVADLPALHAAGIRTIVCNRPDRESADQPDLAEIRAAAAPLGIAVHHLPVEPGRITDDHVAQFRA
LLASAVGPTLAYCRTGTRSATLWALSQAGRMRADDIVATAAAAGYDLAALAPRLAAGSADATRAPDARHEIVIVGAGAAG
IAVASSLLARERTLDIAIVDPADVHYYQPGWTMVGAGVFEAGTTARAIADVLPRGVQRIRAAVAAFEPDAHAVVLDDGRR
IGYGKLIVCAGLKLDWQAIDGLADTLGRHGVTSNYRYDLAPYTWQLVQAFRGGNALFTQPPMPIKCAGAPQKAMYLSCDH
WQRTGRLGAAHVEFLNAGNALFGVADYVPALMAYVKRYGIALSFGHNLVAIDGPARRATFVRTLPDGGTETVVRAFDMIH
VVPPQKAPDFVRTSALADAAGWVDVDPATLRHRRYADIFALGDVTNTTNAKTAAAARKQAPVVAHNVLASLGRAAGEAAY
DGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLLDGRRPSRLAWLLKARVLPPLYWDAMLKGREWLAQPAIVR

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI10864011, Length=422, Percent_Identity=37.4407582938389, Blast_Score=310, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI115534373, Length=349, Percent_Identity=35.5300859598854, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17539680, Length=432, Percent_Identity=30.787037037037, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24657386, Length=396, Percent_Identity=35.6060606060606, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI24657391, Length=396, Percent_Identity=35.6060606060606, Blast_Score=248, Evalue=6e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 59004; Mature: 58873

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRTLTDTLAVSPQIAVADLPALHAAGIRTIVCNRPDRESADQPDLAEIRAAAAPLGIA
CCCHHHHHHHHCCCCEEEECCCHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEE
VHHLPVEPGRITDDHVAQFRALLASAVGPTLAYCRTGTRSATLWALSQAGRMRADDIVAT
EEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEHHHCCCCCHHHHHHH
AAAAGYDLAALAPRLAAGSADATRAPDARHEIVIVGAGAAGIAVASSLLARERTLDIAIV
HHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHEEEEEEE
DPADVHYYQPGWTMVGAGVFEAGTTARAIADVLPRGVQRIRAAVAAFEPDAHAVVLDDGR
CCCCCEEECCCCEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
RIGYGKLIVCAGLKLDWQAIDGLADTLGRHGVTSNYRYDLAPYTWQLVQAFRGGNALFTQ
EECCCCEEEEECCEECHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHCCCCEEEEC
PPMPIKCAGAPQKAMYLSCDHWQRTGRLGAAHVEFLNAGNALFGVADYVPALMAYVKRYG
CCCCEEECCCCCCEEEEECHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
IALSFGHNLVAIDGPARRATFVRTLPDGGTETVVRAFDMIHVVPPQKAPDFVRTSALADA
EEEEECCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHC
AGWVDVDPATLRHRRYADIFALGDVTNTTNAKTAAAARKQAPVVAHNVLASLGRAAGEAA
CCCEECCHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
YDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLLDGRRPSRLAWLLKARVLPPLYWDA
CCCCCCCCEEEECCCEEEEEHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHH
MLKGREWLAQPAIVR
HHHCHHHHCCCCCCC
>Mature Secondary Structure 
TLRTLTDTLAVSPQIAVADLPALHAAGIRTIVCNRPDRESADQPDLAEIRAAAAPLGIA
CCHHHHHHHHCCCCEEEECCCHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEE
VHHLPVEPGRITDDHVAQFRALLASAVGPTLAYCRTGTRSATLWALSQAGRMRADDIVAT
EEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEHHHCCCCCHHHHHHH
AAAAGYDLAALAPRLAAGSADATRAPDARHEIVIVGAGAAGIAVASSLLARERTLDIAIV
HHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHEEEEEEE
DPADVHYYQPGWTMVGAGVFEAGTTARAIADVLPRGVQRIRAAVAAFEPDAHAVVLDDGR
CCCCCEEECCCCEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
RIGYGKLIVCAGLKLDWQAIDGLADTLGRHGVTSNYRYDLAPYTWQLVQAFRGGNALFTQ
EECCCCEEEEECCEECHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHCCCCEEEEC
PPMPIKCAGAPQKAMYLSCDHWQRTGRLGAAHVEFLNAGNALFGVADYVPALMAYVKRYG
CCCCEEECCCCCCEEEEECHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
IALSFGHNLVAIDGPARRATFVRTLPDGGTETVVRAFDMIHVVPPQKAPDFVRTSALADA
EEEEECCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHC
AGWVDVDPATLRHRRYADIFALGDVTNTTNAKTAAAARKQAPVVAHNVLASLGRAAGEAA
CCCEECCHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
YDGYGSCPLTVERGKIVLAEFLYGGKVAPTFPAWLLDGRRPSRLAWLLKARVLPPLYWDA
CCCCCCCCEEEECCCEEEEEHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHH
MLKGREWLAQPAIVR
HHHCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]