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The map label for this gene is acoR [H]

Identifier: 161524604

GI number: 161524604

Start: 1573760

End: 1575676

Strand: Reverse

Name: acoR [H]

Synonym: Bmul_1431

Alternate gene names: 161524604

Gene position: 1575676-1573760 (Counterclockwise)

Preceding gene: 161524611

Following gene: 161524601

Centisome position: 45.69

GC content: 71.36

Gene sequence:

>1917_bases
ATGCCTTACGTCGTTCCCCAGGCCCAGCATGCGGACCGCGTGCTCGGTGCGCTCGCCGGCCGTTTGCCGCCGCCGGCCGA
TTCGACGCGCCTCGTCTCGTCATGGCAGCGCTCGCTCGAGCGCTACCGGCTCGACCCCGCGTCGTCGATCGGCCCGCGCG
TGCTGACCGCGGCCGAGCTGCGCGAGGTGCGCGACAAGGAAGAAGCCTTTCTGCGCGCATCGGGCCAGTGCCTGACGCGG
CTGCACGAGATGATCCGCGTCGCCGATTACTGCGTGATGCTGACCGACGCGCACGGCGTGACGATCGACTATCGGATCGA
TCGCGAGCGCCGCAACGACTTTCGCCATGCGGGGCTGCACATCGGCTCGTGCTGGTCGGAGAGCGAGGAAGGCACGTGCG
GCGTCGCGAGCGTGCTGACCGATCTCGCGCCGATCACCGTGCACAAGACCGACCATTTCCGCGCCGCGTTCACGACGCTC
ACCTGCAGCGCGGCGCCGATCTTTTCGCCGGCCGGCGAGCTGATCGGCGTGCTCGACGCGTCGGCCGTGCAGTCGCCCGA
CAATCGCGACAGCCAGCGTCTCGTCTATCAGCTCGTGCGACAGAGCGCGGCGCTGATCGAGGACGGCTACTTCGTGCACA
GCACGGCGCAGCACTGGATCCTGTTCGGGCATCCTAATCGTCACTACGTCGAGGCGCAGCCCGAATGGCTGATCGCGTTC
GACGAATGCGGCAACATCGTCGCCGCCAACCGGCGCGCGCGCGACGCGCTGCCGGAGCTGCGCGAGCCGCGCCACATCGA
CGAGATTTTCGACGTGACCGACATGCCGCTGCGCGACGCCGCGCGGCTCGACGCGATCGTCGCGCTGCGCCTGCGCGCGA
CCGGTGCGACACTGCATGCGCGGCTGCGCGCGCCGTTGCGCCGCGCGGGACGCGACGCCGGCAGCGCATCGCGCCGGCCG
GGCGCGACCGAGCGCCACGTCGGCGCGCTGACGCCGTTCCTGCACAGCAGCGACGCGCGCGTCGCGCAGCAGGCCGAACT
CGCGCTGCGCGTCGCGAGCAAGCGCCTGCCGATTCTCGTGCTCGGCGAAACCGGCGCGGGCAAGGAAGTGTTCGCCCGGG
CGATCCACGATGCCGGCGCGCGGCGCACGCGGCCGTTCGTCGCCGTCAATTGCGGCGCGCTGCCCGAAGCGCTGATCGAG
AGCGAACTGTTCGGCTACGCGGCCGGCGCGTTCACGGGCGCACGCAAGCACGGCGCGCGCGGCAAGATCGCGCAGGCCGA
CGGCGGCACGCTGTTTCTCGACGAAATCGGCGACATGCCGCTCGCGCTGCAAACGCGCCTGCTGCGCGTGCTTGCCGACG
GCGAAGTCGTGCCGCTCGGCAGCGACACGCCGGTGCGCGTCGATCTCGACGTGATCTGCGCGACGCACCGCGATCTCGCG
CAGATGGTCGCGGCCGGCACGTTCCGCGAGGATCTCTATTACCGGCTCAGCGGCGCGACGTTCGAGCTGCCGCCGTTGCG
CGAACGCGCCGACGTGCGCGACCTGATCGCAGCCGTGTTCGCCGAGGAAGCGCAGGCGACCGGCCACGTGCTGACGCTCG
ACACGACGCTCGCCGAGCAGCTCGCCGCCTATCCGTGGCCCGGCAACGTGCGTCAGTTGCGCAACGTGATGCGCTATGCC
TGCGCGGTATGCGACGGCGCACGCGTGACGCGGCGCGATCTGCCGGCCGACGTCGCCGCGCAGCTCGGTGCGGATACCGG
CAGCGTGCTGCCCGACGACGAACGCAGCCGCATCGTCGCGGCGCTGACCGCGCACCGCTGGCGGCCCGATGCGGCTGCGC
AGGCGCTCGGCATGTCGCGCGCGACGCTGTACCGGCGCATCGCGAAATACCGGATCGTCGCGCCGCACCGCGTGTGA

Upstream 100 bases:

>100_bases
ACGTCTCACGCGTCTCGCGTGCTGCGGCGCAATGTGATCCGCCGAAACGGATGTGCTACAAGAGCATCGAATTCCCCGTC
GTACGGAACCGGAGCCGACC

Downstream 100 bases:

>100_bases
CGCGCGCGCCGATCCGCGCGCGCATGCCGTGTCGCGCGCGTCACGTGTGTCACGCGGTTTCGGCGGGCGCCGCGGGCGCG
TCGTCGCGGGCCGCGGCCGC

Product: Fis family GAF modulated sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MPYVVPQAQHADRVLGALAGRLPPPADSTRLVSSWQRSLERYRLDPASSIGPRVLTAAELREVRDKEEAFLRASGQCLTR
LHEMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLHIGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTL
TCSAAPIFSPAGELIGVLDASAVQSPDNRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
DECGNIVAANRRARDALPELREPRHIDEIFDVTDMPLRDAARLDAIVALRLRATGATLHARLRAPLRRAGRDAGSASRRP
GATERHVGALTPFLHSSDARVAQQAELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRTRPFVAVNCGALPEALIE
SELFGYAAGAFTGARKHGARGKIAQADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDLA
QMVAAGTFREDLYYRLSGATFELPPLRERADVRDLIAAVFAEEAQATGHVLTLDTTLAEQLAAYPWPGNVRQLRNVMRYA
CAVCDGARVTRRDLPADVAAQLGADTGSVLPDDERSRIVAALTAHRWRPDAAAQALGMSRATLYRRIAKYRIVAPHRV

Sequences:

>Translated_638_residues
MPYVVPQAQHADRVLGALAGRLPPPADSTRLVSSWQRSLERYRLDPASSIGPRVLTAAELREVRDKEEAFLRASGQCLTR
LHEMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLHIGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTL
TCSAAPIFSPAGELIGVLDASAVQSPDNRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
DECGNIVAANRRARDALPELREPRHIDEIFDVTDMPLRDAARLDAIVALRLRATGATLHARLRAPLRRAGRDAGSASRRP
GATERHVGALTPFLHSSDARVAQQAELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRTRPFVAVNCGALPEALIE
SELFGYAAGAFTGARKHGARGKIAQADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDLA
QMVAAGTFREDLYYRLSGATFELPPLRERADVRDLIAAVFAEEAQATGHVLTLDTTLAEQLAAYPWPGNVRQLRNVMRYA
CAVCDGARVTRRDLPADVAAQLGADTGSVLPDDERSRIVAALTAHRWRPDAAAQALGMSRATLYRRIAKYRIVAPHRV
>Mature_637_residues
PYVVPQAQHADRVLGALAGRLPPPADSTRLVSSWQRSLERYRLDPASSIGPRVLTAAELREVRDKEEAFLRASGQCLTRL
HEMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLHIGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTLT
CSAAPIFSPAGELIGVLDASAVQSPDNRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAFD
ECGNIVAANRRARDALPELREPRHIDEIFDVTDMPLRDAARLDAIVALRLRATGATLHARLRAPLRRAGRDAGSASRRPG
ATERHVGALTPFLHSSDARVAQQAELALRVASKRLPILVLGETGAGKEVFARAIHDAGARRTRPFVAVNCGALPEALIES
ELFGYAAGAFTGARKHGARGKIAQADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDLAQ
MVAAGTFREDLYYRLSGATFELPPLRERADVRDLIAAVFAEEAQATGHVLTLDTTLAEQLAAYPWPGNVRQLRNVMRYAC
AVCDGARVTRRDLPADVAAQLGADTGSVLPDDERSRIVAALTAHRWRPDAAAQALGMSRATLYRRIAKYRIVAPHRV

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=317, Percent_Identity=42.5867507886435, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI87082117, Length=302, Percent_Identity=43.046357615894, Blast_Score=208, Evalue=9e-55,
Organism=Escherichia coli, GI1790299, Length=313, Percent_Identity=41.2140575079872, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI1788905, Length=234, Percent_Identity=47.4358974358974, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1790437, Length=291, Percent_Identity=41.9243986254296, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1788550, Length=298, Percent_Identity=39.261744966443, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1789087, Length=303, Percent_Identity=42.2442244224422, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786524, Length=290, Percent_Identity=43.7931034482759, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI87082152, Length=247, Percent_Identity=46.1538461538462, Blast_Score=187, Evalue=3e-48,
Organism=Escherichia coli, GI1787583, Length=351, Percent_Identity=35.8974358974359, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI87081872, Length=298, Percent_Identity=37.248322147651, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI87081858, Length=554, Percent_Identity=22.5631768953069, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=39.917695473251, Blast_Score=134, Evalue=2e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69845; Mature: 69714

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYVVPQAQHADRVLGALAGRLPPPADSTRLVSSWQRSLERYRLDPASSIGPRVLTAAEL
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
REVRDKEEAFLRASGQCLTRLHEMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHHHHHHHHCCE
IGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTLTCSAAPIFSPAGELIGVLDA
EECCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHEEEECCCCCCCCHHHHHHHHHH
SAVQSPDNRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCEEECCCCEEEEE
DECGNIVAANRRARDALPELREPRHIDEIFDVTDMPLRDAARLDAIVALRLRATGATLHA
HHCCCEEECCCHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHEEEEECCCHHHHH
RLRAPLRRAGRDAGSASRRPGATERHVGALTPFLHSSDARVAQQAELALRVASKRLPILV
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEE
LGETGAGKEVFARAIHDAGARRTRPFVAVNCGALPEALIESELFGYAAGAFTGARKHGAR
EECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GKIAQADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDLA
CCEEECCCCEEEHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEHHEEECCHHHHH
QMVAAGTFREDLYYRLSGATFELPPLRERADVRDLIAAVFAEEAQATGHVLTLDTTLAEQ
HHHHHCCHHHHHHEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
LAAYPWPGNVRQLRNVMRYACAVCDGARVTRRDLPADVAAQLGADTGSVLPDDERSRIVA
HHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHH
ALTAHRWRPDAAAQALGMSRATLYRRIAKYRIVAPHRV
HHHHHCCCCCHHHHHHCCHHHHHHHHHHHHEECCCCCC
>Mature Secondary Structure 
PYVVPQAQHADRVLGALAGRLPPPADSTRLVSSWQRSLERYRLDPASSIGPRVLTAAEL
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
REVRDKEEAFLRASGQCLTRLHEMIRVADYCVMLTDAHGVTIDYRIDRERRNDFRHAGLH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEECHHHHHHHHHHCCE
IGSCWSESEEGTCGVASVLTDLAPITVHKTDHFRAAFTTLTCSAAPIFSPAGELIGVLDA
EECCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHEEEECCCCCCCCHHHHHHHHHH
SAVQSPDNRDSQRLVYQLVRQSAALIEDGYFVHSTAQHWILFGHPNRHYVEAQPEWLIAF
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCEEECCCCEEEEE
DECGNIVAANRRARDALPELREPRHIDEIFDVTDMPLRDAARLDAIVALRLRATGATLHA
HHCCCEEECCCHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHEEEEECCCHHHHH
RLRAPLRRAGRDAGSASRRPGATERHVGALTPFLHSSDARVAQQAELALRVASKRLPILV
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEE
LGETGAGKEVFARAIHDAGARRTRPFVAVNCGALPEALIESELFGYAAGAFTGARKHGAR
EECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GKIAQADGGTLFLDEIGDMPLALQTRLLRVLADGEVVPLGSDTPVRVDLDVICATHRDLA
CCEEECCCCEEEHHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEHHEEECCHHHHH
QMVAAGTFREDLYYRLSGATFELPPLRERADVRDLIAAVFAEEAQATGHVLTLDTTLAEQ
HHHHHCCHHHHHHEEECCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
LAAYPWPGNVRQLRNVMRYACAVCDGARVTRRDLPADVAAQLGADTGSVLPDDERSRIVA
HHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHH
ALTAHRWRPDAAAQALGMSRATLYRRIAKYRIVAPHRV
HHHHHCCCCCHHHHHHCCHHHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]