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The map label for this gene is trpS [H]

Identifier: 161524352

GI number: 161524352

Start: 1293983

End: 1295185

Strand: Direct

Name: trpS [H]

Synonym: Bmul_1177

Alternate gene names: 161524352

Gene position: 1293983-1295185 (Clockwise)

Preceding gene: 161524351

Following gene: 161524353

Centisome position: 37.52

GC content: 64.92

Gene sequence:

>1203_bases
ATGTTCCCAGATCGTATCTTCTCCGGCATGCGACCCACCGGGTCGCTGCACCTCGGCCATTACCATGGCGTGCTGAAAAA
CTGGGTGAAACTGCAGTCCGAGTACCCGTGTTTCTTCTGTGTCGTCGACTGGCATGCGCTGACGACGCACTACGAGACGC
CCGAGGTCATCGAGAAGAACGTATGGGACGTGCTGATCGACTGGCTCGCCGCCGGCATCGATCCCGCGCAGGCGACGCTG
TTCATCCAGAGCAAGGTACCGGAGCACGCGGAACTCGCGCTGCTGCTCGGCATGAGCACGCCGCTCGGCTGGCTCGAACG
CGTGCCGACCTACAAGGAGCAGATCGAGAAGCTGAAGGACAAGGATCTGTCGACCTACGGCTTCCTCGGCTACCCGGTGC
TGATGGCCGCCGACATCCTGCTGTACCGCGGCTCGCTCGTGCCGGTCGGCGAGGATCAGGTGCCGCACGTCGAGATGACG
CGCGAGATCGCACGCCGCTTCAACTACCTGTACGGCCGCGAACCGGGCTTCGAGGAGAAGGCGCTCGAGGCCGCGAAGAA
GCTCGGCGGCAAGCGCGCGAAGCTCTACCACGAGCTGCGCAACGCCTATCAACAGGAAGGCGACGACGAGGCGCTCGAAC
AGGCGCGGGCGATGCTGCAGGAATCGCAGAGCCTGTCGATGAGCGATCGCGAGCGCCTGTTCGGCTATCTGGAAGGTGCG
CGCAAGATCATCCTCGTCGAGCCGCAGGCACTGCTGACCGAAGCGTCGCGGATGCCGGGCCTCGACGGGCAGAAGATGTC
GAAGTCGTACGGCAACACGATCGGCCTGCGCGAAGACGCCGAGACGATCACGAAAAAGGTCCGCACGATGCCGACCGATC
CGGCGCGCGTGCGCCGCAGCGATCCGGGCGATCCGGACAAGTGCCCGGTGTGGCAGCTGCACCAGGTCTATACGGACGAA
GCGACGCACGAATGGGTGCAGAAGGGCTGCCGTTCGGCCGGCATCGGCTGTCTCGACTGCAAGCAGCCCGTGATCGAAGG
CATCCTGCGCGAGCAGCAGCCGATGCTCGAGCGCGCGCAGAAATACATGGACGATCCGTCGCTGCTGCGCGCGATCGTCG
CGGACGGCTGCGACAAGGCGCGCAAGCACGCGACCGAAACGATGCGCGACGTGCGCGACGCGATGGGCCTGTCGTACACC
TGA

Upstream 100 bases:

>100_bases
GCGTGCTGACGAATTTCTGGCTGCGTCCGCTCGTCAACGTCGGCGCGGACGTCCTGAACGCCATCCTGACTCCTTTGGCC
TTGCTTTTCTAACGACAATC

Downstream 100 bases:

>100_bases
TCGCATGCGTGAACCGATCCTCGCCGCCGCGGGCGGCCATGTCGCCCAGACCGAGCCGTCGCGCTGGGTCGTGCGCTGGT
CGCCGCTCGTGCGCGCGCAC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLAAGIDPAQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREPGFEEKALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRSDPGDPDKCPVWQLHQVYTDE
ATHEWVQKGCRSAGIGCLDCKQPVIEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKHATETMRDVRDAMGLSYT

Sequences:

>Translated_400_residues
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLAAGIDPAQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREPGFEEKALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRSDPGDPDKCPVWQLHQVYTDE
ATHEWVQKGCRSAGIGCLDCKQPVIEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKHATETMRDVRDAMGLSYT
>Mature_400_residues
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKNVWDVLIDWLAAGIDPAQATL
FIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKDKDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMT
REIARRFNYLYGREPGFEEKALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRSDPGDPDKCPVWQLHQVYTDE
ATHEWVQKGCRSAGIGCLDCKQPVIEGILREQQPMLERAQKYMDDPSLLRAIVADGCDKARKHATETMRDVRDAMGLSYT

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=189, Percent_Identity=41.7989417989418, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI41352700, Length=169, Percent_Identity=43.7869822485207, Blast_Score=142, Evalue=7e-34,
Organism=Escherichia coli, GI1789786, Length=167, Percent_Identity=46.7065868263473, Blast_Score=166, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71982800, Length=176, Percent_Identity=35.7954545454545, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71982793, Length=176, Percent_Identity=35.7954545454545, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320474, Length=184, Percent_Identity=36.9565217391304, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24666151, Length=172, Percent_Identity=42.4418604651163, Blast_Score=151, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 45417; Mature: 45417

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWDVLIDWLAAGIDPAQATLFIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKD
HHHHHHHHHHCCCCHHHHEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHH
KDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMTREIARRFNYLYGREPGFEEK
CCCCHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
ALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRS
CEEEEECCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHCCC
DPGDPDKCPVWQLHQVYTDEATHEWVQKGCRSAGIGCLDCKQPVIEGILREQQPMLERAQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARKHATETMRDVRDAMGLSYT
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFPDRIFSGMRPTGSLHLGHYHGVLKNWVKLQSEYPCFFCVVDWHALTTHYETPEVIEKN
CCCHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCHHHHHHH
VWDVLIDWLAAGIDPAQATLFIQSKVPEHAELALLLGMSTPLGWLERVPTYKEQIEKLKD
HHHHHHHHHHCCCCHHHHEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHH
KDLSTYGFLGYPVLMAADILLYRGSLVPVGEDQVPHVEMTREIARRFNYLYGREPGFEEK
CCCCHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
ALEAAKKLGGKRAKLYHELRNAYQQEGDDEALEQARAMLQESQSLSMSDRERLFGYLEGA
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
RKIILVEPQALLTEASRMPGLDGQKMSKSYGNTIGLREDAETITKKVRTMPTDPARVRRS
CEEEEECCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHCCC
DPGDPDKCPVWQLHQVYTDEATHEWVQKGCRSAGIGCLDCKQPVIEGILREQQPMLERAQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KYMDDPSLLRAIVADGCDKARKHATETMRDVRDAMGLSYT
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]