Click here to switch to the map view.

The map label for this gene is iscR [H]

Identifier: 161524318

GI number: 161524318

Start: 1260884

End: 1261423

Strand: Direct

Name: iscR [H]

Synonym: Bmul_1143

Alternate gene names: 161524318

Gene position: 1260884-1261423 (Clockwise)

Preceding gene: 161524317

Following gene: 161524319

Centisome position: 36.56

GC content: 66.85

Gene sequence:

>540_bases
ATGAGACTCACCACCAAAGGCCGTTTCGCCGTCACGGCGATGATCGACTTGGCACTGCGCCAGGAGCAGGGCCCGGTGAC
GCTTGCAGGCATCAGCCAGCGCCAGCGGATTTCGCTCTCGTATCTCGAACAGCTGTTCGGCAAGCTGCGCAGGCATGAAA
TCGTCGAATCCGTGCGCGGCCCGGGCGGCGGCTACAACCTCGCGCGCCGCGCGCAGGACGTGACCGTTGCCGACATCATC
ATCGCGGTCGACGAACCGCTCGACGCGACGCAATGCGGCGGCAAGGGCACGTGCGACGGCTCGAAGCAGCCGGACGGCCA
CTGCATGACGCACGAGCTGTGGTCGACGCTGAACCAGAAAATGGTCGAATACCTCGATTCCGTGTCGCTGCAGGATCTCG
TCGATCAGCAGCGCGCACGCGAAGGCGCGCCCGCAGTGCTGCGCGACCGGCGCGCGCCGGAGCCCGTCGCCGCGCCGGCC
GAGCCGGTGCGCACGATGCCGCTCGGTCCCAATTCGGTGTTCAACATCGCGAGTTCGTGA

Upstream 100 bases:

>100_bases
GCGATCTGCGAATACCCTGCCGAAGACATGGATACTTGACTAAAATCGTCAAATATTTATACTTGACCAAAATCGTCAAG
ATTGCAGTCCCCTAGACACC

Downstream 100 bases:

>100_bases
GCGCGAACCGCGCCACACCCTATAACGCATATCGTCCCTGCACAGAATCCCGGAGCGACAGATGACTCAACAGACCCTCC
ACCTGCCCATCTACATGGAT

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAQDVTVADII
IAVDEPLDATQCGGKGTCDGSKQPDGHCMTHELWSTLNQKMVEYLDSVSLQDLVDQQRAREGAPAVLRDRRAPEPVAAPA
EPVRTMPLGPNSVFNIASS

Sequences:

>Translated_179_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAQDVTVADII
IAVDEPLDATQCGGKGTCDGSKQPDGHCMTHELWSTLNQKMVEYLDSVSLQDLVDQQRAREGAPAVLRDRRAPEPVAAPA
EPVRTMPLGPNSVFNIASS
>Mature_179_residues
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRGPGGGYNLARRAQDVTVADII
IAVDEPLDATQCGGKGTCDGSKQPDGHCMTHELWSTLNQKMVEYLDSVSLQDLVDQQRAREGAPAVLRDRRAPEPVAAPA
EPVRTMPLGPNSVFNIASS

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=137, Percent_Identity=51.8248175182482, Blast_Score=140, Evalue=6e-35,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 19522; Mature: 19522

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYNLARRAQDVTVADIIIAVDEPLDATQCGGKGTCDGSKQPDGHCMTHELWSTLNQK
CCCCCHHHHHHCCCEEHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MVEYLDSVSLQDLVDQQRAREGAPAVLRDRRAPEPVAAPAEPVRTMPLGPNSVFNIASS
HHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCEECCCCCCHHHCCCCC
>Mature Secondary Structure
MRLTTKGRFAVTAMIDLALRQEQGPVTLAGISQRQRISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYNLARRAQDVTVADIIIAVDEPLDATQCGGKGTCDGSKQPDGHCMTHELWSTLNQK
CCCCCHHHHHHCCCEEHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MVEYLDSVSLQDLVDQQRAREGAPAVLRDRRAPEPVAAPAEPVRTMPLGPNSVFNIASS
HHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCEECCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]