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The map label for this gene is nuoN [H]

Identifier: 161524217

GI number: 161524217

Start: 1138091

End: 1139566

Strand: Direct

Name: nuoN [H]

Synonym: Bmul_1041

Alternate gene names: 161524217

Gene position: 1138091-1139566 (Clockwise)

Preceding gene: 161524216

Following gene: 161524218

Centisome position: 33.0

GC content: 64.3

Gene sequence:

>1476_bases
ATGAACGCTCCTATGAATGTCCTGTTGCCTGACGCGCTGGTGATGGCCGCCATCATCGTCGCTTGGCTGAACGACACCTT
TACCGGTGCATCCGGCCGCCGCCTCACGTATCTGATCGCGGTGGTCTCGTCGGTGGTCGCCGGCGTCTGGTTTGCGGTGC
AGGCGCTCGATCCGCAGCATTACTACTTCTTCTCGCGGATGGTCGTCGTCGATGCGTTCGCGAGCGCGATGAAGGCGGTC
GTGTCGCTCGGTTTCGCCGTGTCGCTGATCTATTCGCGCAAGTACCTCGAAGATCGCGACATGTTCCGCGGCGACGTGTT
CCTGCTCGGCATGTTCTCGCTGCTCGGTCAGCTCGTGATGATCTCGGGCAACAACTTCCTGACGCTGTACCTCGGCCTCG
AGCTGATGTCGCTGTCGCTGTACGCGGTGATCGCACTGCGTCGCGACGGTGCGGTGTCGAGCGAAGCCGCGATGAAGTAC
TACGTGCTGGGCGCGCTCGCTTCGGGCTTCGTGCTGTACGGGATCTCGATGCTGTACGGCGCGACGGGCGGCTCGCTCGA
TCTCGCCGACGTGTACAAGGCCGTGAGCAGCGGCGGCACCGAAGACGCGGTGCTGATGTTCGGCGTGATCTTCATCGTGG
CCGGTATCGCGTTCAAGCTTGGCGCCGTGCCGTTCCACATGTGGGTGCCCGACGTCTATCAGGGCGCGCCGACCGCGATG
ACGCTGTTCGTCGGCGGCGGTCCGAAGGTCGCGGCGTTCGCCTGGGGCCTGCGTTTCCTGGTGATGGGCCTGCTGCCGCT
CGCGCAGAACTGGCAGACCGCGCTCGTGATTCTCGCCGCGCTGTCGCTGATCGTCGGCAACATCACGGGTATCGTCCAGC
GCAACATCAAGCGGATGCTCGCGTACTCGGCGATCTCGAACATGGGCTTCGTGCTGCTCGGCCTGCTCGCCGGCATCGTG
AAGGGCGACGCGGCCGCACCGGCGAACGCGTACAGCTCGGCGATGTTCTACGCGATCGTCTACCTGATCACAACGCTCGG
CTCGTTCGGCGTGGTGATGCTGCTCGCGCGCCGCGACTTCGAAGCCGAGACGATCGACGACTTCAAGGGTCTCAACAAGC
GCAGCCCGGTGTTCGCGTTCGTGATGATGGTCATGATGTTCTCGCTGGCCGGCATTCCGCCGACCGTCGGCTTCTACGCG
AAGCTCGCGGTGCTCGAGGCGACCGTCAACGCGGGCCTCACGTGGCTGGCCGTGCTGGCCGTGATCACGTCGCTGTTCGG
CGCGTTCTACTACCTGCGCATCGTCAAGCTGATCTACTTCGATGCACCGCAAGACTCGACGCCGATCGGCGGCGATTTCT
GCAAGCGCACGATCCTGGTGCTCAACGGCATCGCGGTCGTCGTGCTCGGCCTGATCCCGAGCCCGCTGCTGACGGTGTGC
CTGGACGCACTCCGTCACTCGCTGCCGACGCTGTAA

Upstream 100 bases:

>100_bases
CACCGACGTGATGCACGTTTCCGTGGAAAACCTCCTCTCCCATGTCGCGCAGTCGAAGCTGCCGCTGGCCCAGTAATCGC
GAGCGGAGGAAATCAAGATC

Downstream 100 bases:

>100_bases
TGTCGGCCGCGGGCTGGTTTATCGTGCTGTTGGCGCTCGCGGGCGCCAACCTGCCGTTTCTGAACCAGCGCCTGTTCGCC
GTCGTGCCGATCGGCGCGGC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MNAPMNVLLPDALVMAAIIVAWLNDTFTGASGRRLTYLIAVVSSVVAGVWFAVQALDPQHYYFFSRMVVVDAFASAMKAV
VSLGFAVSLIYSRKYLEDRDMFRGDVFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYAVIALRRDGAVSSEAAMKY
YVLGALASGFVLYGISMLYGATGGSLDLADVYKAVSSGGTEDAVLMFGVIFIVAGIAFKLGAVPFHMWVPDVYQGAPTAM
TLFVGGGPKVAAFAWGLRFLVMGLLPLAQNWQTALVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGIV
KGDAAAPANAYSSAMFYAIVYLITTLGSFGVVMLLARRDFEAETIDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYA
KLAVLEATVNAGLTWLAVLAVITSLFGAFYYLRIVKLIYFDAPQDSTPIGGDFCKRTILVLNGIAVVVLGLIPSPLLTVC
LDALRHSLPTL

Sequences:

>Translated_491_residues
MNAPMNVLLPDALVMAAIIVAWLNDTFTGASGRRLTYLIAVVSSVVAGVWFAVQALDPQHYYFFSRMVVVDAFASAMKAV
VSLGFAVSLIYSRKYLEDRDMFRGDVFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYAVIALRRDGAVSSEAAMKY
YVLGALASGFVLYGISMLYGATGGSLDLADVYKAVSSGGTEDAVLMFGVIFIVAGIAFKLGAVPFHMWVPDVYQGAPTAM
TLFVGGGPKVAAFAWGLRFLVMGLLPLAQNWQTALVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGIV
KGDAAAPANAYSSAMFYAIVYLITTLGSFGVVMLLARRDFEAETIDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYA
KLAVLEATVNAGLTWLAVLAVITSLFGAFYYLRIVKLIYFDAPQDSTPIGGDFCKRTILVLNGIAVVVLGLIPSPLLTVC
LDALRHSLPTL
>Mature_491_residues
MNAPMNVLLPDALVMAAIIVAWLNDTFTGASGRRLTYLIAVVSSVVAGVWFAVQALDPQHYYFFSRMVVVDAFASAMKAV
VSLGFAVSLIYSRKYLEDRDMFRGDVFLLGMFSLLGQLVMISGNNFLTLYLGLELMSLSLYAVIALRRDGAVSSEAAMKY
YVLGALASGFVLYGISMLYGATGGSLDLADVYKAVSSGGTEDAVLMFGVIFIVAGIAFKLGAVPFHMWVPDVYQGAPTAM
TLFVGGGPKVAAFAWGLRFLVMGLLPLAQNWQTALVILAALSLIVGNITGIVQRNIKRMLAYSAISNMGFVLLGLLAGIV
KGDAAAPANAYSSAMFYAIVYLITTLGSFGVVMLLARRDFEAETIDDFKGLNKRSPVFAFVMMVMMFSLAGIPPTVGFYA
KLAVLEATVNAGLTWLAVLAVITSLFGAFYYLRIVKLIYFDAPQDSTPIGGDFCKRTILVLNGIAVVVLGLIPSPLLTVC
LDALRHSLPTL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=328, Percent_Identity=25.3048780487805, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI145693160, Length=469, Percent_Identity=33.4754797441365, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1788614, Length=413, Percent_Identity=24.2130750605327, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788827, Length=331, Percent_Identity=27.4924471299094, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788831, Length=306, Percent_Identity=25.1633986928105, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI2367154, Length=148, Percent_Identity=27.7027027027027, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788613, Length=445, Percent_Identity=25.6179775280899, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52629; Mature: 52629

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA