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The map label for this gene is nuoD [H]

Identifier: 161524207

GI number: 161524207

Start: 1126195

End: 1127448

Strand: Direct

Name: nuoD [H]

Synonym: Bmul_1031

Alternate gene names: 161524207

Gene position: 1126195-1127448 (Clockwise)

Preceding gene: 161524206

Following gene: 161524208

Centisome position: 32.66

GC content: 62.44

Gene sequence:

>1254_bases
ATGGCAGAAATCAAGAACTACACGCTCAACTTCGGCCCGCAGCACCCGGCAGCGCACGGCGTGCTGCGCCTCGTGCTCGA
GCTCGACGGCGAAGTCATCCAGCGCGCCGATCCGCATATCGGCCTGCTGCACCGCGCGACCGAAAAGCTCGCGGAAAACA
AGACCTTCATCCAGTCCGTGCCGTACATGGACCGTCTCGACTACGTGTCGATGATGGTCAACGAGCACGGCTACGTGCTC
GCGATCGAGAAGCTGCTCGGCATCGCGGTGCCGGAGCGCGCGCAGTACATCCGCGTGCTGTTCGACGAAATCACGCGCGT
GCTGAACCACCTGATGTGGATCGGCGCGCACGCACTCGACGTCGGCGCGATGGCGGTGTTCCTGTACGCCTTCCGCGAGC
GCGAAGACCTGATGGACGTGTACGAAGCGGTGTCCGGTGCACGGATGCACGCGGCGTACTATCGTCCGGGCGGCGTCTAT
CGCGACCTGCCGGACGCGATGCCGCAATACAAGGCGTCGAAGATCCGCAACGAGAAGGCGCTCGCGAAGATGAACGAAGC
GCGCAGCGGCTCGGTGCTCGATTTCATCGACGACTTCTTCACGCGCTTCCCGAAGTGCATCGACGAGTACGAAACGCTGC
TGACCGACAACCGGATCTGGAAACAGCGTCTGGTCGGCATCGGCGTCGTGAGTCCGGAGCGTGCGCTGCAGATGGGGCTC
ACCGGCCCGATGCTGCGCGGCTCGGGCATCGCGTGGGATCTGCGCAAGAAGCAGCCGTACGAAGTGTACGACCGCATGGA
TTTCGACGTGCCGGTCGGCGTGAACGGCGATTGCTACGACCGCTATCTGGTGCGCGTCGAGGAAATGCGTCAGTCGGTCC
GCATCGCGAAACAGTGTATTGAGTGGCTCCGCAAGAATCCGGGCCCCGTGATGACGGACAATCACAAGGTTGCGCCGCCG
TCGCGCGTCGGCATGAAGACCAACATGGAAGACTTGATTCACCACTTCAAGCTCTTCACCGAAGGTTTCCATGTGCCGGA
AGGCGAAGCGTACGCGGCGGTCGAGCATCCGAAGGGCGAGTTCGGCATCTATCTCGTGTCCGACGGTGCCAACAAGCCGT
ATCGTCTCAAGATTCGCGCACCGGGCTTCGCGCACCTGGCGTCGCTCGACGAAATGGCGCGCGGTCACATGATCGCCGAC
GCCGTCACCATCATCGGTACGCAGGACATCGTGTTCGGCGAAATCGATCGCTAA

Upstream 100 bases:

>100_bases
GCGCGTCGTGTACCAGCCGGTGACGATCGAGCCGCGCGAAATCACGCCGCGCGTGATCCGCGAGGATCGCTATGGCGGTC
TGAAACATTAAGGGGGCGTC

Downstream 100 bases:

>100_bases
TGGTTGCGCCGCCTGCGCGAGCGGGCGGCGAGCAGTAAGTCACACGCGATGCGCGCTGAACCGGCGCGGCTTCGCAAGCT
GTCAACAGTGAGCGCCAGGT

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMVNEHGYVL
AIEKLLGIAVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPDAMPQYKASKIRNEKALAKMNEARSGSVLDFIDDFFTRFPKCIDEYETLLTDNRIWKQRLVGIGVVSPERALQMGL
TGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSVRIAKQCIEWLRKNPGPVMTDNHKVAPP
SRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIAD
AVTIIGTQDIVFGEIDR

Sequences:

>Translated_417_residues
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMVNEHGYVL
AIEKLLGIAVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPDAMPQYKASKIRNEKALAKMNEARSGSVLDFIDDFFTRFPKCIDEYETLLTDNRIWKQRLVGIGVVSPERALQMGL
TGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSVRIAKQCIEWLRKNPGPVMTDNHKVAPP
SRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIAD
AVTIIGTQDIVFGEIDR
>Mature_416_residues
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMVNEHGYVLA
IEKLLGIAVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYR
DLPDAMPQYKASKIRNEKALAKMNEARSGSVLDFIDDFFTRFPKCIDEYETLLTDNRIWKQRLVGIGVVSPERALQMGLT
GPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSVRIAKQCIEWLRKNPGPVMTDNHKVAPPS
RVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIADA
VTIIGTQDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=414, Percent_Identity=61.5942028985507, Blast_Score=520, Evalue=1e-147,
Organism=Homo sapiens, GI260898743, Length=408, Percent_Identity=60.7843137254902, Blast_Score=503, Evalue=1e-142,
Organism=Escherichia coli, GI145693162, Length=410, Percent_Identity=38.2926829268293, Blast_Score=301, Evalue=6e-83,
Organism=Escherichia coli, GI1789076, Length=422, Percent_Identity=27.9620853080569, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788832, Length=408, Percent_Identity=27.6960784313726, Blast_Score=114, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17555284, Length=415, Percent_Identity=59.5180722891566, Blast_Score=492, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17568379, Length=415, Percent_Identity=58.3132530120482, Blast_Score=488, Evalue=1e-138,
Organism=Drosophila melanogaster, GI24638644, Length=415, Percent_Identity=60.7228915662651, Blast_Score=525, Evalue=1e-149,
Organism=Drosophila melanogaster, GI221459469, Length=412, Percent_Identity=55.5825242718447, Blast_Score=469, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 47413; Mature: 47282

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSV
CCCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHC
PYMDRLDYVSMMVNEHGYVLAIEKLLGIAVPERAQYIRVLFDEITRVLNHLMWIGAHALD
CCHHHHHHHHHHHCCCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDAMPQYKASKIRNEKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LAKMNEARSGSVLDFIDDFFTRFPKCIDEYETLLTDNRIWKQRLVGIGVVSPERALQMGL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCC
TGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSVRIAKQCI
CCCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKNPGPVMTDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIADAVTIIGTQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure 
AEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSV
CCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHC
PYMDRLDYVSMMVNEHGYVLAIEKLLGIAVPERAQYIRVLFDEITRVLNHLMWIGAHALD
CCHHHHHHHHHHHCCCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDAMPQYKASKIRNEKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LAKMNEARSGSVLDFIDDFFTRFPKCIDEYETLLTDNRIWKQRLVGIGVVSPERALQMGL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCC
TGPMLRGSGIAWDLRKKQPYEVYDRMDFDVPVGVNGDCYDRYLVRVEEMRQSVRIAKQCI
CCCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKNPGPVMTDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGEAYAAVEHPKGE
HHHHCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLVSDGANKPYRLKIRAPGFAHLASLDEMARGHMIADAVTIIGTQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA