Click here to switch to the map view.

The map label for this gene is nuoC [H]

Identifier: 161524206

GI number: 161524206

Start: 1125583

End: 1126185

Strand: Direct

Name: nuoC [H]

Synonym: Bmul_1030

Alternate gene names: 161524206

Gene position: 1125583-1126185 (Clockwise)

Preceding gene: 161524205

Following gene: 161524207

Centisome position: 32.64

GC content: 64.01

Gene sequence:

>603_bases
ATGGCAAGCAAAATCGAGACCCTCAAGGCCAACCTCGAAGCCGCGCTCGGCGCGCGCGTGGTGAGCCTTACCGAAGCGAT
CGGTGAACTGACGCTCGTCGTGAAGGCGAGCGATTACCTCGACGTCGCGACGACGCTGCGCGACGATCCGAAGCTGCGCT
TCGAGCAACTGATCGACCTGTGCGGCGTCGACTACCAGACCTACGGCGACGGCGCCTACGACGGCCCGCGCTTCGCGGCC
GTCACGCACCTGCTGTCGGTCACGAACAACTGGCGTCTGCGTCTGCGCGTGTTCGCACCCGACGACGATCTGCCGATCGT
TCCGTCGCTCGTCGACATCTGGAATTCCGCGAACTGGTACGAGCGCGAGGCGTTCGACCTGTACGGCATCGTGTTCGAAG
GCCACCCCGACCTGCGCCGCATCCTCACCGACTACGGCTTCATCGGCCACCCGTTCCGCAAGGACTTCCCGGTGTCGGGC
TACGTCGAAATGCGTTACGACCCGGAAGAGAAGCGCGTCGTGTACCAGCCGGTGACGATCGAGCCGCGCGAAATCACGCC
GCGCGTGATCCGCGAGGATCGCTATGGCGGTCTGAAACATTAA

Upstream 100 bases:

>100_bases
CCGACGGCCGAGGCGCTGGTCTACGGCGTGATCCAGCTTCAGGCGAAGATCCGCCGCACCAACACCATCGCCCGTCAATA
AGCCCCGAGCGTCCCCCAAT

Downstream 100 bases:

>100_bases
GGGGGCGTCATGGCAGAAATCAAGAACTACACGCTCAACTTCGGCCCGCAGCACCCGGCAGCGCACGGCGTGCTGCGCCT
CGTGCTCGAGCTCGACGGCG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLDVATTLRDDPKLRFEQLIDLCGVDYQTYGDGAYDGPRFAA
VTHLLSVTNNWRLRLRVFAPDDDLPIVPSLVDIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH

Sequences:

>Translated_200_residues
MASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLDVATTLRDDPKLRFEQLIDLCGVDYQTYGDGAYDGPRFAA
VTHLLSVTNNWRLRLRVFAPDDDLPIVPSLVDIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH
>Mature_199_residues
ASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLDVATTLRDDPKLRFEQLIDLCGVDYQTYGDGAYDGPRFAAV
THLLSVTNNWRLRLRVFAPDDDLPIVPSLVDIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGY
VEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=155, Percent_Identity=47.741935483871, Blast_Score=144, Evalue=6e-35,
Organism=Escherichia coli, GI145693162, Length=156, Percent_Identity=35.2564102564103, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=149, Percent_Identity=44.2953020134228, Blast_Score=130, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI32563621, Length=149, Percent_Identity=44.2953020134228, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24656494, Length=160, Percent_Identity=45, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22879; Mature: 22748

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLDVATTLRDDPKLRFEQLIDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHCCCCCHHHHHHHHH
CGVDYQTYGDGAYDGPRFAAVTHLLSVTNNWRLRLRVFAPDDDLPIVPSLVDIWNSANWY
HCCCCEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCCC
EREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTI
CCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCEE
EPREITPRVIREDRYGGLKH
CCHHCCHHHHHCCCCCCCCC
>Mature Secondary Structure 
ASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLDVATTLRDDPKLRFEQLIDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHCCCCCHHHHHHHHH
CGVDYQTYGDGAYDGPRFAAVTHLLSVTNNWRLRLRVFAPDDDLPIVPSLVDIWNSANWY
HCCCCEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHCCCCCC
EREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTI
CCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCEE
EPREITPRVIREDRYGGLKH
CCHHCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA