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The map label for this gene is htpG [H]

Identifier: 161524108

GI number: 161524108

Start: 1020877

End: 1022775

Strand: Direct

Name: htpG [H]

Synonym: Bmul_0932

Alternate gene names: 161524108

Gene position: 1020877-1022775 (Clockwise)

Preceding gene: 161524107

Following gene: 161524109

Centisome position: 29.6

GC content: 63.77

Gene sequence:

>1899_bases
ATGGCACACGAAACGATGAGCTTTCAGGCAGAGGTCAAGCAGCTCCTCCACCTGATGATTCATTCGCTCTACAGCAACAA
GGAAATCTTCCTGCGCGAACTGGTGTCGAACGCGTCCGACGCGGCCGACAAGCTGCGTTTCGAGGCGCTCGCGGACAACG
CGCTCTACGAGGACGATCCGAACCTGCGCATCCGCATCGGCTACGACAAGGCCGCGCGCACGATCACGATCGACGACAAC
GGGATCGGGATGAGCCGCGACGAGGCGATCGCGAACCTCGGCACGATCGCGCGCTCGGGCACGAAGGAATTCTTCTCGAA
GCTGTCGGGCGACCAGCAGAAGGATGCGGCGCTGATCGGCCAGTTCGGCGTGGGCTTCTACTCGGGCTTCATCGTCGCGG
ACAAGATCACCGTCGAGACGCGCCGCGCGGGCCTGCCGGCGACCGAAGGCGTGCGCTGGGAAAGCGCGGGCGAGGGCGAT
TTCACGATCGACGCGATCGAGCGCGCGCAGCGCGGCACCACGATCACGCTGCATCTGCGCGAAGGCGAGGACGAACTGCT
GTCGTCGTACCGGCTGAAGTCGATCATCCAGAAGTATTCCGACCACATCGCGCTGCCGATCCTGATGAAGAAGGAAGAAT
GGGATCAGGAAAAGGGCGAGATGGTCGTCAAGGACGACGACGAGACCGTCAACCAGGCGAGCGCGCTGTGGACGCGGCCG
AAGAGCGACATCACCGACGAGCAGTACAAGCAGTTCTATCAGCACATCGCGCACGATCACCAGGATCCGCTCACGTGGAC
GCACAACCGCGTCGAAGGTCGCAGCGAATACACGCAGCTGCTGTACGTGCCGTCGCAGGCGCCGTTCGACCTGTGGAACC
GCGATTATCGCGGCGGCCTGAAGCTGTACGTGAAGCGCGTGTTCATCATGGACGACGCCGAGCAGCTGCTGCCGCAATAC
CTGCGCTTCGTGAAGGGTGTCGTCGATTCGGCCGATCTGCCGCTGAACGTATCGCGTGAAATCCTGCAGGAAAGCCGCGA
CGTCAAGGCGATCCGCGAAGGCGTGACCAAGCGCGCGCTGTCGATGCTCGAAGAGCTCGCGAATGCGGAAGACGATGCCG
GCAAGGAGAAGTACAAGACGTTCTGGCGCGCGTTCGGCCAGGTGCTGAAGGAAGGCGTCGGCGAGGATCACGCGAACCGC
GAGCGCATCGCCAAGCTGCTGCGCTTCGCGTCGACGCACGGCGACACCGATGCGCAGGACGTGTCGCTCGCCGACTACGT
CGCGCGCATGAAGCCCGAGCAGACGAAGATCTACTACGTGACGGCCGACACGTGGCAGGCCGCGAAGAACAGCCCGCATC
TCGAGGTGTTCCGCAAGAAGGGCGTCGAGGTGCTGCTGCTGACCGATCGCGTCGACGAATGGATGCTGTCGTTCCTGCAC
GAGTTCGACGGCAAGCCGCTCGCGAGCGTCGCGCGCGGCGATCTCGATCTCGGCGCGCTGAACGACGAGGAGAAGAAGGC
GCAGGAAGAGGCCGGCGAAGCGATCAAGCCGGTCGTCGAGAAGATGAAGGAAGCGCTCGGCGACAAGGTGAAGGACGTGC
GCGTCACGTTCCGTCTGACCGATTCGCCGTCGTGCCTCGTCGCGGACGACAACGACATGAGCGGCTACCTGCAGCGGATG
CTGAAGGCGGCCGGCCAGAAGGCGCCGTCGTTCCAGCCGATTCTCGAGATCAACCCCGAGCATGCGCTCGTCAAGCAGCT
GAAGGCCGACAGCGCCGATTTCGGCGACTGGTGCCATCTGCTGTTCGATCAGGCGCTGCTTGCCGAAGGCGGGATGCTCG
ACGATCCGGCGAGCTTCGTGAAGCGGACCAACGCGCTGCTGCTGTCGCGCGCCGCGTGA

Upstream 100 bases:

>100_bases
CCGCTTGCGCCAGGCGGTTGTCCCTAGACGGGCCGGCCGGCATCGCGCGCCGGACGCCTGCGCCACACCACTCAAGTTCA
AGTAAGAGGAAACAGCATCC

Downstream 100 bases:

>100_bases
GTGCGCGGATGCGATTCGACGCCGCGCTTGCGGGCTGGCGCGACACGCCGCGGCCCGGCTGCACGCCGGACCAGCGCGAC
TGGCTCACGCGCGGCGGTTC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MAHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALADNALYEDDPNLRIRIGYDKAARTITIDDN
GIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPATEGVRWESAGEGD
FTIDAIERAQRGTTITLHLREGEDELLSSYRLKSIIQKYSDHIALPILMKKEEWDQEKGEMVVKDDDETVNQASALWTRP
KSDITDEQYKQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLYVPSQAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQY
LRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWRAFGQVLKEGVGEDHANR
ERIAKLLRFASTHGDTDAQDVSLADYVARMKPEQTKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
EFDGKPLASVARGDLDLGALNDEEKKAQEEAGEAIKPVVEKMKEALGDKVKDVRVTFRLTDSPSCLVADDNDMSGYLQRM
LKAAGQKAPSFQPILEINPEHALVKQLKADSADFGDWCHLLFDQALLAEGGMLDDPASFVKRTNALLLSRAA

Sequences:

>Translated_632_residues
MAHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALADNALYEDDPNLRIRIGYDKAARTITIDDN
GIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPATEGVRWESAGEGD
FTIDAIERAQRGTTITLHLREGEDELLSSYRLKSIIQKYSDHIALPILMKKEEWDQEKGEMVVKDDDETVNQASALWTRP
KSDITDEQYKQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLYVPSQAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQY
LRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWRAFGQVLKEGVGEDHANR
ERIAKLLRFASTHGDTDAQDVSLADYVARMKPEQTKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
EFDGKPLASVARGDLDLGALNDEEKKAQEEAGEAIKPVVEKMKEALGDKVKDVRVTFRLTDSPSCLVADDNDMSGYLQRM
LKAAGQKAPSFQPILEINPEHALVKQLKADSADFGDWCHLLFDQALLAEGGMLDDPASFVKRTNALLLSRAA
>Mature_631_residues
AHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALADNALYEDDPNLRIRIGYDKAARTITIDDNG
IGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPATEGVRWESAGEGDF
TIDAIERAQRGTTITLHLREGEDELLSSYRLKSIIQKYSDHIALPILMKKEEWDQEKGEMVVKDDDETVNQASALWTRPK
SDITDEQYKQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLYVPSQAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQYL
RFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWRAFGQVLKEGVGEDHANRE
RIAKLLRFASTHGDTDAQDVSLADYVARMKPEQTKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLHE
FDGKPLASVARGDLDLGALNDEEKKAQEEAGEAIKPVVEKMKEALGDKVKDVRVTFRLTDSPSCLVADDNDMSGYLQRML
KAAGQKAPSFQPILEINPEHALVKQLKADSADFGDWCHLLFDQALLAEGGMLDDPASFVKRTNALLLSRAA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=686, Percent_Identity=39.5043731778426, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI4507677, Length=688, Percent_Identity=37.6453488372093, Blast_Score=427, Evalue=1e-119,
Organism=Homo sapiens, GI155722983, Length=637, Percent_Identity=35.4788069073783, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI154146191, Length=411, Percent_Identity=40.8759124087591, Blast_Score=289, Evalue=7e-78,
Organism=Homo sapiens, GI153792590, Length=416, Percent_Identity=40.3846153846154, Blast_Score=286, Evalue=6e-77,
Organism=Escherichia coli, GI1786679, Length=630, Percent_Identity=62.0634920634921, Blast_Score=804, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=677, Percent_Identity=38.5524372230428, Blast_Score=454, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17542208, Length=678, Percent_Identity=38.2005899705015, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115535205, Length=645, Percent_Identity=33.0232558139535, Blast_Score=317, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI115535167, Length=432, Percent_Identity=35.6481481481481, Blast_Score=253, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6323840, Length=682, Percent_Identity=39.5894428152493, Blast_Score=464, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6325016, Length=414, Percent_Identity=40.0966183574879, Blast_Score=302, Evalue=1e-82,
Organism=Drosophila melanogaster, GI17647529, Length=686, Percent_Identity=39.6501457725948, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21357739, Length=677, Percent_Identity=37.5184638109306, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24586016, Length=652, Percent_Identity=35.2760736196319, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71287; Mature: 71156

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALADNALYEDDP
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
NLRIRIGYDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIG
CEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
QFGVGFYSGFIVADKITVETRRAGLPATEGVRWESAGEGDFTIDAIERAQRGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCEEEEEEE
EGEDELLSSYRLKSIIQKYSDHIALPILMKKEEWDQEKGEMVVKDDDETVNQASALWTRP
CCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHCHHHCCEEEECCCHHHHHHHHHHCCC
KSDITDEQYKQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLYVPSQAPFDLWNRDYRGGL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPQYLRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEELANAEDDAGKEKYKTFWRAFGQVLKEGVGEDHANRERIAKLLRFASTHGDTDAQD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHH
VSLADYVARMKPEQTKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
HHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHH
EFDGKPLASVARGDLDLGALNDEEKKAQEEAGEAIKPVVEKMKEALGDKVKDVRVTFRLT
HCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
DSPSCLVADDNDMSGYLQRMLKAAGQKAPSFQPILEINPEHALVKQLKADSADFGDWCHL
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHHHH
LFDQALLAEGGMLDDPASFVKRTNALLLSRAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALADNALYEDDP
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
NLRIRIGYDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIG
CEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
QFGVGFYSGFIVADKITVETRRAGLPATEGVRWESAGEGDFTIDAIERAQRGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCEEEEEEE
EGEDELLSSYRLKSIIQKYSDHIALPILMKKEEWDQEKGEMVVKDDDETVNQASALWTRP
CCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHCHHHCCEEEECCCHHHHHHHHHHCCC
KSDITDEQYKQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLYVPSQAPFDLWNRDYRGGL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPQYLRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEELANAEDDAGKEKYKTFWRAFGQVLKEGVGEDHANRERIAKLLRFASTHGDTDAQD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHH
VSLADYVARMKPEQTKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
HHHHHHHHHCCCCCCEEEEEECCCHHHHCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHH
EFDGKPLASVARGDLDLGALNDEEKKAQEEAGEAIKPVVEKMKEALGDKVKDVRVTFRLT
HCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
DSPSCLVADDNDMSGYLQRMLKAAGQKAPSFQPILEINPEHALVKQLKADSADFGDWCHL
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHHHH
LFDQALLAEGGMLDDPASFVKRTNALLLSRAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA