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The map label for this gene is lysN [H]

Identifier: 161524104

GI number: 161524104

Start: 1016061

End: 1017242

Strand: Reverse

Name: lysN [H]

Synonym: Bmul_0928

Alternate gene names: 161524104

Gene position: 1017242-1016061 (Counterclockwise)

Preceding gene: 161524105

Following gene: 161524103

Centisome position: 29.5

GC content: 69.63

Gene sequence:

>1182_bases
ATGAATCCGAGCGACCTGCACCCGCCGCACTGGCAGCTTTCCGAACGCGCCCGCAAGCTGACGAGCTCGGCGATCCGCGA
GATCCTGAAGGTCACGGAACGCCCCGAGGTCATCTCGTTCGCCGGCGGCCTGCCCGCCCCCGCGACGTTCCCGGCCGAGC
GCATGCGCGCGGCCGCCGACCGCGTGCTGCGCGACGCGCCGGCCGCGGCGCTGCAGTACAGCGCGACCGAAGGCTATCTG
CCGCTGCGCGAGTGGATCGCCGAGCGCTATCGCGTGCGCGTGTCGCAGGTGCTGGTCACGACCGGCTCGCAGCAGGCGCT
CGACCTGCTCGGCAAGGCGCTCGTCGATCCGGGCAGCCCGATCCTCGTCGAAACGCCGACCTACCTCGGCGCGCTGCAGT
CGTTCTCGCTGTACGAGCCGCGCTACGTGCAGTTGCCGACCGACGAACAGGGCCTGCTGCCCGACGGCCTGACGCCCGCG
CTCACGCAGGGCGCGCGCCTGCTGTACGCGCAGCCGAACTTCCAGAATCCGACGGGCCGCCGCCTGCCGGTCGAGCGCCG
CCGCGCGCTGGCCGCATTCGCGCAGACGAGCCCGTTCCCGGTGCTCGAAGACGATCCGTACGGCGCACTGAACTATCAGG
GCGAGCCGCTGCCGACGATGCTGTCGATGGCGCCCGACCACATCGTGCACCTCGGCACGTTCTCGAAGGTGCTCGCGCCG
GGCCTGCGGATCGGCTACATCATTGCGCCCGAGGAACTGCACTTCAAGCTCGTGCAGGCAAAGCAGGCCACCGACCTGCA
CACGCCGACGCTCACGCAGCGCATCGCACATGAGGTGATCAAGGACGGCTTCCTCGACGAGCACATCCCGACGATCCGCC
AGCTGTACGGCGCGCAGTGCGAAGCGATGCTCGGCGCGCTCGCGCGTCACATGCCGGAAGGCGTCACGTGGAACCGCCCG
GAAGGCGGGATGTTCATCTGGGTGAACCTGCCGAAGCAGATCGACAGCATGGCGCTGCTCGCGACGGCGGTCGAGCATCA
CGTCGCCTTCGTGCCGGGCGCGCCTTTCTTCGCGAACGACGCGCAGCAGAACACGCTGCGCCTGTCGTTCGTGACGGTGC
CGCCCGAGAAGATCGAGGAAGGCGTCGCGCGGCTCGGCAAGCTGATCCGCGAGCGCCTCTGA

Upstream 100 bases:

>100_bases
CGACGGCACGCACGCGCTCGCGCATGCCGACCCGGCTGCGTCGACGCGATCGGCCCGATCGACCTTTCTTGACTGACCAC
GATATCCGAACGAGGAGACT

Downstream 100 bases:

>100_bases
TCCGCCCTTTTTCCTGTCAAGACTCACTACGAGGAACGAACGCATGGCTAACGTCTACGACAAACTGAAATCGCTGGGCA
TCGAACTGCCGAGCGCCGGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYRVRVSQVLVTTGSQQALDLLGKALVDPGSPILVETPTYLGALQSFSLYEPRYVQLPTDEQGLLPDGLTPA
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQCEAMLGALARHMPEGVTWNRP
EGGMFIWVNLPKQIDSMALLATAVEHHVAFVPGAPFFANDAQQNTLRLSFVTVPPEKIEEGVARLGKLIRERL

Sequences:

>Translated_393_residues
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYRVRVSQVLVTTGSQQALDLLGKALVDPGSPILVETPTYLGALQSFSLYEPRYVQLPTDEQGLLPDGLTPA
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQCEAMLGALARHMPEGVTWNRP
EGGMFIWVNLPKQIDSMALLATAVEHHVAFVPGAPFFANDAQQNTLRLSFVTVPPEKIEEGVARLGKLIRERL
>Mature_393_residues
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAADRVLRDAPAAALQYSATEGYL
PLREWIAERYRVRVSQVLVTTGSQQALDLLGKALVDPGSPILVETPTYLGALQSFSLYEPRYVQLPTDEQGLLPDGLTPA
LTQGARLLYAQPNFQNPTGRRLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQCEAMLGALARHMPEGVTWNRP
EGGMFIWVNLPKQIDSMALLATAVEHHVAFVPGAPFFANDAQQNTLRLSFVTVPPEKIEEGVARLGKLIRERL

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=411, Percent_Identity=29.1970802919708, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI33469970, Length=411, Percent_Identity=29.1970802919708, Blast_Score=180, Evalue=2e-45,
Organism=Escherichia coli, GI1787710, Length=381, Percent_Identity=28.6089238845144, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1790797, Length=338, Percent_Identity=28.4023668639053, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788722, Length=358, Percent_Identity=24.3016759776536, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321236, Length=487, Percent_Identity=23.6139630390144, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6321929, Length=491, Percent_Identity=23.0142566191446, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321000, Length=257, Percent_Identity=27.6264591439689, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21356535, Length=392, Percent_Identity=26.2755102040816, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43453; Mature: 43453

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDAPAAALQYSATEGYLPLREWIAERYRVRVSQVLVTTGSQQALDLLGKALVDPGSP
HHHHHCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCCCCC
ILVETPTYLGALQSFSLYEPRYVQLPTDEQGLLPDGLTPALTQGARLLYAQPNFQNPTGR
EEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCC
RLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EAMLGALARHMPEGVTWNRPEGGMFIWVNLPKQIDSMALLATAVEHHVAFVPGAPFFAND
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEECCCCCCCCCC
AQQNTLRLSFVTVPPEKIEEGVARLGKLIRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPSDLHPPHWQLSERARKLTSSAIREILKVTERPEVISFAGGLPAPATFPAERMRAAAD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHH
RVLRDAPAAALQYSATEGYLPLREWIAERYRVRVSQVLVTTGSQQALDLLGKALVDPGSP
HHHHHCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHCCCCCC
ILVETPTYLGALQSFSLYEPRYVQLPTDEQGLLPDGLTPALTQGARLLYAQPNFQNPTGR
EEEECCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCEEEEECCCCCCCCCC
RLPVERRRALAAFAQTSPFPVLEDDPYGALNYQGEPLPTMLSMAPDHIVHLGTFSKVLAP
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHEEEHHHHHHHHCC
GLRIGYIIAPEELHFKLVQAKQATDLHTPTLTQRIAHEVIKDGFLDEHIPTIRQLYGAQC
CCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EAMLGALARHMPEGVTWNRPEGGMFIWVNLPKQIDSMALLATAVEHHVAFVPGAPFFAND
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHEEECCCCCCCCCC
AQQNTLRLSFVTVPPEKIEEGVARLGKLIRERL
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA