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The map label for this gene is yciR [C]

Identifier: 161524101

GI number: 161524101

Start: 1012128

End: 1014464

Strand: Reverse

Name: yciR [C]

Synonym: Bmul_0925

Alternate gene names: 161524101

Gene position: 1014464-1012128 (Counterclockwise)

Preceding gene: 161524102

Following gene: 161524100

Centisome position: 29.42

GC content: 66.5

Gene sequence:

>2337_bases
ATGAGCTTCGCCCGGTCATCCCACCCGCCGCCGCCGCGGCTGCGCACGCCGCGCAAGTCGAGGCGCCGGGCGCTATTCGC
GATCCCGCTGCTCGGGATGCTCGCGCTGGCGCTGCTGTGGGCCGTGATCATCGCGCGGCTGTCGGTCGAGAAGGACAGCG
CGTACAAGGAGGCGGCCGCGTCGGCGGCGATCCTGTCGTCCGCGCTCGAACAGCACACGGTCAAGGCGATCCACCAGGTC
GACCAGATCACGCGCTTCGTCAAGTTCGAGTTCGAGAAGTCGCCCGCGCACTTCAATCTCGCGAGCGCGGTCGAGAAAGG
CGTCGTGCCGAGCGACACGCTGATCCAGGTCTCGCTCGTCAACGCGAAGGGCATGCTGTTCGCGAACACGGCCGAAACGC
GCCCGCAAGCGATCAACCTGTCCGATCGCGAGCACTTCCAGGTCCATCTCGCGCACAACGACGACCGCCTCTACATCAGC
AAGCCCGTGCTCGGCCGCGTATCGGGCCACTGGACGCTGCAGATGACGCGGCGGCTGAACAATCCGGACGGCAGTTTCGC
GGGCATCGTCGTCGTGTCGGAAGACCCGAGCTACTTCACGAACGACTTCTACAACAACGCGGCGATCGGCAAGGAAGGCG
TGATCGCGGTCGTCTCCGACACGGGCGCCGTGCTCGCGCGCCGCACCGGTTCGGTCAGCAATGCGCCCGGCGCGTTCTCG
GCATCGGGCGTCTATCCGATCGCCGAGCGCGTGACGGGGACGATCGCCGATCCGATCGACGGCGTCACGCGCATCGTGTC
GTACCGTCACCTCGACGGCTATCCGCTCGCGGTGATGGTCGGGCTGTCGCAGGCCGAGGAGTTCGCGGACTACTACCACA
CGCGCAACGTCTATCTGCTGATGACGAGCTTCATCACGCTCGCGATGCTCGCCTTCTTCGGTGTCGCGACGGGCCTGATC
GGCAAGCTGCTCGGCCGCGAGCGCGAGATGACGCAGCTCGCCGAATACGACCTGCTGACCGGCCTCGCGAACCGCTACGC
GACGCTGCGCGGGCTGCGCAACGACGTGTCGATGCCGTCGAGCCTGTCGCGGCTCGGGCTGCTGTTCATCGATCTCGACA
ACTTCAAGACCGTCAACGACACACTCGGCCACAACGCCGGCGACATCGTGCTGCAGATGACGGCATCGCGCCTGTCGGAT
GCCGTCGGCGACGAAGGCACGCTCGCGCGCATCGGCGGCGACGAGTTCGTCGTCGTGATGAAGGGCGACGACGTCGAACG
GCGCGCGGTACGGCTTGCCGAGGCGATCATCCGGATGTTCGCCGAGCCGTTCGACGTGCGCGGCAGCTCGTTCGTGCTGC
ACGCGAGCATCGGCATCGCGCTGCACACGGTCGCGAACGAAAGCGAGATCGACCTGCTGAAGAAGGCCGACCTCGCAATG
TACAGCGCGAAGGACGCCGGCAAGAACTGCTATCAGTTCTATGCGCCGCATCTGTCGCATCGCGCCGATCATCTGATGCG
CTGGGAGCAGCAGCTGCGCGTCGCGCTCGCCGAGGGGCAGCTGTTCCTCGCGTACCAGCCGAAGATCGATCTCGCGCACC
GCACGATCACGGGCTTCGAGGCGCTCGCGCGCTGGGATCATCCGGAGCACGGGATCATCTCCGCGAACGAGTTCATTTCG
ATTGCCGAATCCACCGGGCTCATCGTGCCGATCGGCGATTTCGTGATCCGCACCGCATGCCGGCAGATTGCGCGCTGGCG
CGAGGAAGGCCACGACACGCTGACGCTCGCCGTCAACATCTCGCCCGTGCAGTTCTGGCGCGGCGACCTGATCGAGACGA
TCTCGGGCGCGCTGCGCGAAACCGGCATCGACGCGAACCGCCTCGAGATCGAGATCACCGAGACCGCGATGATGGAATAT
CCGGAGCTCGTGTCCGAGAAGATCGTCGCGCTGAAGAAGCTCGGCATCCGGATCGCGCTCGACGACTTCGGCACCGGCTA
TTCGTCGCTGTCGTACCTTCACCGCTTCTCGGTCGACACGCTGAAGGTCGACCGCTCGTTCGTGCAGGCGATTCCGCACG
ATCGCAGCGTGTGCGTAATGGTCGCGTCGATCGTGCATCTCGCGCGTTCGCTCGGGCTGACCGTCGTCGTCGAGGGCACC
GAGACCGACGAGCAGATCGCGTGGCTGTCCGCGCTCGGCGAGATCGAGGCACAGGGCTTCCTGTTCTCGCGGCCGGTGCC
GGCCGACGCGATCCCCGCGCTGATCGCGCGCTTCGGCGTGCGCGGCGACCATCCGAACGTCGTACCGCACCGCGCGGCCG
GCGGCACGAGTGCCTGA

Upstream 100 bases:

>100_bases
CCCGGTATTCGCGCGCCGCGAACGGGCGGACGCCGCTGCGATCCCACCAGCCGGCCATCCCCCGACGATGGCGTACGCGA
GAGCAGGACGCCGCCCTTCG

Downstream 100 bases:

>100_bases
ACGCATAAGCCGCCGCGCCCTTCCCGCCCGTGCGCCGGCACGCCGACCGATGCGGCCGCATCGATTGGTTCAATTTCCGC
GCCAATTGCGTCATTCGTTT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 778; Mature: 777

Protein sequence:

>778_residues
MSFARSSHPPPPRLRTPRKSRRRALFAIPLLGMLALALLWAVIIARLSVEKDSAYKEAAASAAILSSALEQHTVKAIHQV
DQITRFVKFEFEKSPAHFNLASAVEKGVVPSDTLIQVSLVNAKGMLFANTAETRPQAINLSDREHFQVHLAHNDDRLYIS
KPVLGRVSGHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARRTGSVSNAPGAFS
ASGVYPIAERVTGTIADPIDGVTRIVSYRHLDGYPLAVMVGLSQAEEFADYYHTRNVYLLMTSFITLAMLAFFGVATGLI
GKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPSSLSRLGLLFIDLDNFKTVNDTLGHNAGDIVLQMTASRLSD
AVGDEGTLARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFAEPFDVRGSSFVLHASIGIALHTVANESEIDLLKKADLAM
YSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPKIDLAHRTITGFEALARWDHPEHGIISANEFIS
IAESTGLIVPIGDFVIRTACRQIARWREEGHDTLTLAVNISPVQFWRGDLIETISGALRETGIDANRLEIEITETAMMEY
PELVSEKIVALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPHDRSVCVMVASIVHLARSLGLTVVVEGT
ETDEQIAWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGDHPNVVPHRAAGGTSA

Sequences:

>Translated_778_residues
MSFARSSHPPPPRLRTPRKSRRRALFAIPLLGMLALALLWAVIIARLSVEKDSAYKEAAASAAILSSALEQHTVKAIHQV
DQITRFVKFEFEKSPAHFNLASAVEKGVVPSDTLIQVSLVNAKGMLFANTAETRPQAINLSDREHFQVHLAHNDDRLYIS
KPVLGRVSGHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARRTGSVSNAPGAFS
ASGVYPIAERVTGTIADPIDGVTRIVSYRHLDGYPLAVMVGLSQAEEFADYYHTRNVYLLMTSFITLAMLAFFGVATGLI
GKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPSSLSRLGLLFIDLDNFKTVNDTLGHNAGDIVLQMTASRLSD
AVGDEGTLARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFAEPFDVRGSSFVLHASIGIALHTVANESEIDLLKKADLAM
YSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPKIDLAHRTITGFEALARWDHPEHGIISANEFIS
IAESTGLIVPIGDFVIRTACRQIARWREEGHDTLTLAVNISPVQFWRGDLIETISGALRETGIDANRLEIEITETAMMEY
PELVSEKIVALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPHDRSVCVMVASIVHLARSLGLTVVVEGT
ETDEQIAWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGDHPNVVPHRAAGGTSA
>Mature_777_residues
SFARSSHPPPPRLRTPRKSRRRALFAIPLLGMLALALLWAVIIARLSVEKDSAYKEAAASAAILSSALEQHTVKAIHQVD
QITRFVKFEFEKSPAHFNLASAVEKGVVPSDTLIQVSLVNAKGMLFANTAETRPQAINLSDREHFQVHLAHNDDRLYISK
PVLGRVSGHWTLQMTRRLNNPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARRTGSVSNAPGAFSA
SGVYPIAERVTGTIADPIDGVTRIVSYRHLDGYPLAVMVGLSQAEEFADYYHTRNVYLLMTSFITLAMLAFFGVATGLIG
KLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPSSLSRLGLLFIDLDNFKTVNDTLGHNAGDIVLQMTASRLSDA
VGDEGTLARIGGDEFVVVMKGDDVERRAVRLAEAIIRMFAEPFDVRGSSFVLHASIGIALHTVANESEIDLLKKADLAMY
SAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPKIDLAHRTITGFEALARWDHPEHGIISANEFISI
AESTGLIVPIGDFVIRTACRQIARWREEGHDTLTLAVNISPVQFWRGDLIETISGALRETGIDANRLEIEITETAMMEYP
ELVSEKIVALKKLGIRIALDDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPHDRSVCVMVASIVHLARSLGLTVVVEGTE
TDEQIAWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGDHPNVVPHRAAGGTSA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=431, Percent_Identity=36.4269141531323, Blast_Score=261, Evalue=9e-71,
Organism=Escherichia coli, GI87081921, Length=429, Percent_Identity=34.032634032634, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI226510982, Length=387, Percent_Identity=29.7157622739018, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1787055, Length=429, Percent_Identity=27.7389277389277, Blast_Score=157, Evalue=4e-39,
Organism=Escherichia coli, GI1790496, Length=253, Percent_Identity=32.8063241106719, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1788502, Length=246, Percent_Identity=35.7723577235772, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=34.7280334728033, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=31.6666666666667, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786507, Length=238, Percent_Identity=33.6134453781513, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI87081980, Length=252, Percent_Identity=32.1428571428571, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1788849, Length=239, Percent_Identity=31.7991631799163, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=36.5853658536585, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082096, Length=237, Percent_Identity=30.8016877637131, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788381, Length=200, Percent_Identity=34.5, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786584, Length=198, Percent_Identity=31.3131313131313, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=31.2883435582822, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI87081977, Length=200, Percent_Identity=31, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=33.1325301204819, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87082007, Length=195, Percent_Identity=27.6923076923077, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081881, Length=170, Percent_Identity=34.1176470588235, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787816, Length=168, Percent_Identity=29.7619047619048, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787262, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787410, Length=235, Percent_Identity=22.5531914893617, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 85264; Mature: 85132

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFARSSHPPPPRLRTPRKSRRRALFAIPLLGMLALALLWAVIIARLSVEKDSAYKEAAA
CCCCCCCCCCCCCCCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SAAILSSALEQHTVKAIHQVDQITRFVKFEFEKSPAHFNLASAVEKGVVPSDTLIQVSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHCCCCCCCEEEEEEE
NAKGMLFANTAETRPQAINLSDREHFQVHLAHNDDRLYISKPVLGRVSGHWTLQMTRRLN
CCCCEEEECCCCCCCCEECCCCCCEEEEEEEECCCEEEEECCCEECCCCCEEEEEEECCC
NPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARRTGSVSNAPGAFS
CCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCEEEEEECCCCEEHCCCCCCCCCCCCCC
ASGVYPIAERVTGTIADPIDGVTRIVSYRHLDGYPLAVMVGLSQAEEFADYYHTRNVYLL
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCHHHH
MTSFITLAMLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLSRLGLLFIDLDNFKTVNDTLGHNAGDIVLQMTASRLSDAVGDEGTLARIGGDEFVVVM
HHHHCEEEEEECCCCCCHHHHHCCCCCCEEEEEEHHHHHHHCCCCCCEEEECCCEEEEEE
KGDDVERRAVRLAEAIIRMFAEPFDVRGSSFVLHASIGIALHTVANESEIDLLKKADLAM
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHH
YSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPKIDLAHRTITGFE
EECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHH
ALARWDHPEHGIISANEFISIAESTGLIVPIGDFVIRTACRQIARWREEGHDTLTLAVNI
HHHHCCCCCCCEEEHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
SPVQFWRGDLIETISGALRETGIDANRLEIEITETAMMEYPELVSEKIVALKKLGIRIAL
CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEE
DDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPHDRSVCVMVASIVHLARSLGLTVVVEGT
ECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECC
ETDEQIAWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGDHPNVVPHRAAGGTSA
CCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFARSSHPPPPRLRTPRKSRRRALFAIPLLGMLALALLWAVIIARLSVEKDSAYKEAAA
CCCCCCCCCCCCCCCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
SAAILSSALEQHTVKAIHQVDQITRFVKFEFEKSPAHFNLASAVEKGVVPSDTLIQVSLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHCCCCCCCEEEEEEE
NAKGMLFANTAETRPQAINLSDREHFQVHLAHNDDRLYISKPVLGRVSGHWTLQMTRRLN
CCCCEEEECCCCCCCCEECCCCCCEEEEEEEECCCEEEEECCCEECCCCCEEEEEEECCC
NPDGSFAGIVVVSEDPSYFTNDFYNNAAIGKEGVIAVVSDTGAVLARRTGSVSNAPGAFS
CCCCCEEEEEEEECCCCHHHHHCCCCCCCCCCCEEEEEECCCCEEHCCCCCCCCCCCCCC
ASGVYPIAERVTGTIADPIDGVTRIVSYRHLDGYPLAVMVGLSQAEEFADYYHTRNVYLL
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCHHHH
MTSFITLAMLAFFGVATGLIGKLLGREREMTQLAEYDLLTGLANRYATLRGLRNDVSMPS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLSRLGLLFIDLDNFKTVNDTLGHNAGDIVLQMTASRLSDAVGDEGTLARIGGDEFVVVM
HHHHCEEEEEECCCCCCHHHHHCCCCCCEEEEEEHHHHHHHCCCCCCEEEECCCEEEEEE
KGDDVERRAVRLAEAIIRMFAEPFDVRGSSFVLHASIGIALHTVANESEIDLLKKADLAM
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHH
YSAKDAGKNCYQFYAPHLSHRADHLMRWEQQLRVALAEGQLFLAYQPKIDLAHRTITGFE
EECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHH
ALARWDHPEHGIISANEFISIAESTGLIVPIGDFVIRTACRQIARWREEGHDTLTLAVNI
HHHHCCCCCCCEEEHHHHHEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
SPVQFWRGDLIETISGALRETGIDANRLEIEITETAMMEYPELVSEKIVALKKLGIRIAL
CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEE
DDFGTGYSSLSYLHRFSVDTLKVDRSFVQAIPHDRSVCVMVASIVHLARSLGLTVVVEGT
ECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECC
ETDEQIAWLSALGEIEAQGFLFSRPVPADAIPALIARFGVRGDHPNVVPHRAAGGTSA
CCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]