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The map label for this gene is ttuB [H]

Identifier: 161524051

GI number: 161524051

Start: 956503

End: 957807

Strand: Reverse

Name: ttuB [H]

Synonym: Bmul_0872

Alternate gene names: 161524051

Gene position: 957807-956503 (Counterclockwise)

Preceding gene: 161524052

Following gene: 161524047

Centisome position: 27.77

GC content: 66.82

Gene sequence:

>1305_bases
ATGGCAACATCGACGCAGTCGCTGCCGGGCTCGTCCGGCGCATTCGAGGAAGCAACCTACCGGAAGGTATCGTGGCGGCT
CACGCCGCTGCTGCTGCTCTGCTACGTGGTCGCGTATCTCGACCGCGTCAACGTCGGCTTCGCGAAGCTGCAAATGGCGA
GCGACCTGAATCTCAGCGATACCGTGTACGGGCTCGGCGCGGGCATCTTCTTCTTCGGCTACTTCCTGTTCGAGGTGCCG
AGCAACATCATCCTGCACAAGGTCGGCGCGCGCGTCTGGATCGCGCGGATCATGGCGACGTGGGGCGTGATCTCGATCCT
CACGATGTTCGTGACGACGCCCGCGATGTTCTACGTGATGCGCTTTCTGCTCGGCGTCGCGGAAGCGGGCTTCTTTCCCG
GCGTGATCCTGTACCTGACCTACTGGTATCCCGCGCACCGGCGCGGCCGCATGACGACGTTCTTCATGACGGCCGTCGCG
CTGTCCGGTGTGATCGGCGGCCCGATCTCGGGCTTCATCCTGAAGGCGTTCGACGGCGTCAGCGGCTGGCACGGCTGGCA
GTGGCTGTTCCTGCTCGAAGGCATTCCGTCGGTGCTCGCCGGCGTGCTCGTGTTCTTCGCGCTCGACGACCGGATCGCGA
AAGCGACGTGGCTCACCGACGAGGAAAAGGCGCTGCTCGCGCGCAACGTCGATGCCGAGGAAGCGACGAAGGAAGACCTG
CCGCTCGGCGCGGTGATGGCGAGCCCGCGCGTATGGCTGATGGCGCTGATCTACTTCTCGTTCGTGATGGGGCTGTACGG
CGTCGGCTTCTGGCTGCCGACCATCATCAAGGCGACCGGCGTGACCGACACGCTCGCGATCGGCCTGCTGTCGGCGGTGC
CGTACGCGGCCGCGGTCGTCGCGATGATCCTGATCGCGCGCAGCGCGGACAAGCATCGCGAACGGCGCTGGCACCTCGCG
ATTCCGGCCGCGCTCGGCGCGGTCGGCCTCGTGCTGTCGGTCGTGTGGGCACACGAGACGGCACTCGCGATGCTCGGCCT
CACGCTCGCGACGATCGGCATCCTGACGACGCTCCCGCTGTTCTGGAGCCTGCCGACCGCGTTCCTCGGCGGCGCGGCCG
CCGCTGCCGGCATCGCGATGATCAACTCGATCGGCAACCTCGCGGGCTTCCTGAGCCCCTATCTGATGGGCTGGCTCAAG
CAGGCGACCGGCGCGAACGACGCCGGCATGTACATGCTCGCCGGCTTCCTCGTGCTCGGCGGCCTGCTCGCGCTGTCGGT
GCCGAAGCGGCTCGTCGACAAATGA

Upstream 100 bases:

>100_bases
CCCGGCGCGCGCGCGCCGGCATCGCTGCACCGCAATGCCAAGCACAACAACCGGCGCCGCACCCGCGCGCTGCCGGCTCA
CGACAAGGACAGGAGACAAC

Downstream 100 bases:

>100_bases
TGCCGGCGTACCGCGGCCGCGACTAAGCAGCCGCCCGCGCGCGACACCGAAGAAAAATGCCCCGAAGGCCGTCAGGCGTT
CGGGGCATCGTTTTTTGCTG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MATSTQSLPGSSGAFEEATYRKVSWRLTPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSDTVYGLGAGIFFFGYFLFEVP
SNIILHKVGARVWIARIMATWGVISILTMFVTTPAMFYVMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVA
LSGVIGGPISGFILKAFDGVSGWHGWQWLFLLEGIPSVLAGVLVFFALDDRIAKATWLTDEEKALLARNVDAEEATKEDL
PLGAVMASPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTLAIGLLSAVPYAAAVVAMILIARSADKHRERRWHLA
IPAALGAVGLVLSVVWAHETALAMLGLTLATIGILTTLPLFWSLPTAFLGGAAAAAGIAMINSIGNLAGFLSPYLMGWLK
QATGANDAGMYMLAGFLVLGGLLALSVPKRLVDK

Sequences:

>Translated_434_residues
MATSTQSLPGSSGAFEEATYRKVSWRLTPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSDTVYGLGAGIFFFGYFLFEVP
SNIILHKVGARVWIARIMATWGVISILTMFVTTPAMFYVMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVA
LSGVIGGPISGFILKAFDGVSGWHGWQWLFLLEGIPSVLAGVLVFFALDDRIAKATWLTDEEKALLARNVDAEEATKEDL
PLGAVMASPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTLAIGLLSAVPYAAAVVAMILIARSADKHRERRWHLA
IPAALGAVGLVLSVVWAHETALAMLGLTLATIGILTTLPLFWSLPTAFLGGAAAAAGIAMINSIGNLAGFLSPYLMGWLK
QATGANDAGMYMLAGFLVLGGLLALSVPKRLVDK
>Mature_433_residues
ATSTQSLPGSSGAFEEATYRKVSWRLTPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSDTVYGLGAGIFFFGYFLFEVPS
NIILHKVGARVWIARIMATWGVISILTMFVTTPAMFYVMRFLLGVAEAGFFPGVILYLTYWYPAHRRGRMTTFFMTAVAL
SGVIGGPISGFILKAFDGVSGWHGWQWLFLLEGIPSVLAGVLVFFALDDRIAKATWLTDEEKALLARNVDAEEATKEDLP
LGAVMASPRVWLMALIYFSFVMGLYGVGFWLPTIIKATGVTDTLAIGLLSAVPYAAAVVAMILIARSADKHRERRWHLAI
PAALGAVGLVLSVVWAHETALAMLGLTLATIGILTTLPLFWSLPTAFLGGAAAAAGIAMINSIGNLAGFLSPYLMGWLKQ
ATGANDAGMYMLAGFLVLGGLLALSVPKRLVDK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=259, Percent_Identity=23.5521235521236, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI87082071, Length=413, Percent_Identity=37.5302663438257, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI2367379, Length=427, Percent_Identity=23.6533957845433, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789152, Length=441, Percent_Identity=22.2222222222222, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082320, Length=405, Percent_Identity=21.7283950617284, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789515, Length=428, Percent_Identity=21.9626168224299, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=339, Percent_Identity=26.2536873156342, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6322025, Length=312, Percent_Identity=25.6410256410256, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=318, Percent_Identity=23.8993710691824, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324410, Length=162, Percent_Identity=26.5432098765432, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=213, Percent_Identity=23.4741784037559, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=225, Percent_Identity=23.5555555555556, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321502, Length=352, Percent_Identity=22.4431818181818, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323032, Length=215, Percent_Identity=26.5116279069767, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584153, Length=355, Percent_Identity=23.0985915492958, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24653727, Length=405, Percent_Identity=20.9876543209877, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655271, Length=440, Percent_Identity=24.3181818181818, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130135, Length=440, Percent_Identity=24.3181818181818, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46842; Mature: 46711

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCC
>Mature Secondary Structure 
ATSTQSLPGSSGAFEEATYRKVSWRLTPLLLLCYVVAYLDRVNVGFAKLQMASDLNLSD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCH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HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]