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The map label for this gene is rsmB [H]

Identifier: 161523966

GI number: 161523966

Start: 864522

End: 865787

Strand: Direct

Name: rsmB [H]

Synonym: Bmul_0786

Alternate gene names: 161523966

Gene position: 864522-865787 (Clockwise)

Preceding gene: 161523965

Following gene: 161523967

Centisome position: 25.07

GC content: 69.51

Gene sequence:

>1266_bases
ATGAAGCTGCACGGATTCCTGATCGGCCAGACCGAGACGCTGCTGGCCGAAGTGCTGAAATTTGCCGGTCCCGCCGACGC
GACGACGAGCCGCTTTTTCCGCGCGCATCCGAAGCTCGGCCATGCGGAGCGCGGCGTGATCGCCGAAGCGGTGTTCGCGG
TACTGCGCCGCAAGATGGAGTTCGCGCATCTGGCCGAGAGCGGCACGGGCAGCCCCGCGCGACGCCTGACGCTGCTCGGC
CTGATGCAGACGATGGGCCGCAACGCGCTGAAGCCGTTCGTGTCGCCCGCCGAGGCGGCGTGGCTCGAGCATGTATCGAA
GATCGATCCGGCGAGCCTGCCGGTGCGCATCCGCACGAACCTGCCGGACTGGATCCAGCAGGCGCTGTCGACGCGCTTCG
ATGCCGAGGAGCTTGCGCAGCTCGCCGCCGCGCTGAACTATCCGGCGCCGCTCGATCTGCGCGCGAACGTGCTGAAGGCC
ACGCGCGAGCAGGTGATCGACGCGCTGCGCGCGAACGGCATCGACGCGGGCGAGACGCCGTTCGCACCGCACGGCGTGCG
CGTGGTCGGCAAGCCGGCGCTCACGCGCCTGAAGCTCTTCGAGGAAGGGCAGATCGAGGTGCAGGACGAGGGCAGCCAGC
TGCTGTGCTCGCTCGTCGCGCCGCGTCGCGGCGAGATGGTCGTCGACTTCTGCGCGGGCGCGGGCGGCAAGACGCTCGCG
CTCGGCGCGATGATGCGCTCGACCGGTCGGCTGTATGCGTTCGACGTGTCGGAGAAGCGTCTCGCGAAGCTCAAGCCGCG
CCTCGCGCGCAGCGGGCTGTCGAACGTGAATCCGGTGCTGATCGACAGCGAGCATGACGCGAAGATCAAGCGGCTCGCCG
GCAAGATCGACCGCGTGCTCGTCGACGCGCCGTGCAGCGGTCTCGGCACGCTGCGCCGCAATCCCGACCTGAAGTGGCGT
CAGACGCGCACGTCGGTCGACGAACTCACGCCGAAGCAGGCGTCGATCCTCGCGAGCGCGGCGCGCCTCGTGAAGAAGGG
CGGCCGCCTCGTCTACGCGACCTGCAGCGTGCTCAACGCCGAGAACGAGCGCGTCGTCGAGCAGTTCCTCGCCGATCATC
CGGACTTCGTGCTCGTGCCGGCGCAGAAGGTGCTCGCCGATCAGCGCATCGCGCTCGAGACGGGCGATTACCTCTCGCTG
TGGCCGCACCGCCACGCGACCGACGGCTTCTTCGCGGCCGTGCTCGAGCGGCGCGCGGCGCAGTAA

Upstream 100 bases:

>100_bases
AAGGGCGCCTGCGCCTCGAAGGCGACCGTGCGATCGTCGCGCCCGAAGAGGCGCGCTGGATTTTCGCGGATCAACCGCAA
ACCGAAACGAGCGAGGGTGT

Downstream 100 bases:

>100_bases
CGGAGCAGGGCACGGACGATGGAGAACCGACTGCTGTCGCACCGGCTCGCGTCGGTGATCCGCGACTTCAACGAGCCGGT
CATGATCTGGCAGGCCGCGA

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKMEFAHLAESGTGSPARRLTLLG
LMQTMGRNALKPFVSPAEAAWLEHVSKIDPASLPVRIRTNLPDWIQQALSTRFDAEELAQLAAALNYPAPLDLRANVLKA
TREQVIDALRANGIDAGETPFAPHGVRVVGKPALTRLKLFEEGQIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QTRTSVDELTPKQASILASAARLVKKGGRLVYATCSVLNAENERVVEQFLADHPDFVLVPAQKVLADQRIALETGDYLSL
WPHRHATDGFFAAVLERRAAQ

Sequences:

>Translated_421_residues
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKMEFAHLAESGTGSPARRLTLLG
LMQTMGRNALKPFVSPAEAAWLEHVSKIDPASLPVRIRTNLPDWIQQALSTRFDAEELAQLAAALNYPAPLDLRANVLKA
TREQVIDALRANGIDAGETPFAPHGVRVVGKPALTRLKLFEEGQIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QTRTSVDELTPKQASILASAARLVKKGGRLVYATCSVLNAENERVVEQFLADHPDFVLVPAQKVLADQRIALETGDYLSL
WPHRHATDGFFAAVLERRAAQ
>Mature_421_residues
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKMEFAHLAESGTGSPARRLTLLG
LMQTMGRNALKPFVSPAEAAWLEHVSKIDPASLPVRIRTNLPDWIQQALSTRFDAEELAQLAAALNYPAPLDLRANVLKA
TREQVIDALRANGIDAGETPFAPHGVRVVGKPALTRLKLFEEGQIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QTRTSVDELTPKQASILASAARLVKKGGRLVYATCSVLNAENERVVEQFLADHPDFVLVPAQKVLADQRIALETGDYLSL
WPHRHATDGFFAAVLERRAAQ

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=320, Percent_Identity=29.6875, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI76150623, Length=320, Percent_Identity=29.6875, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI23199998, Length=295, Percent_Identity=30.1694915254237, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI270288818, Length=295, Percent_Identity=30.1694915254237, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI270288816, Length=295, Percent_Identity=30.1694915254237, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI8922322, Length=295, Percent_Identity=30.1694915254237, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI32698918, Length=186, Percent_Identity=30.6451612903226, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI301336155, Length=355, Percent_Identity=25.6338028169014, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI39995082, Length=300, Percent_Identity=26, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI40316918, Length=189, Percent_Identity=31.7460317460317, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI11545785, Length=167, Percent_Identity=32.9341317365269, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367212, Length=259, Percent_Identity=31.6602316602317, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87081985, Length=203, Percent_Identity=32.0197044334975, Blast_Score=99, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17536757, Length=295, Percent_Identity=29.4915254237288, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115534021, Length=228, Percent_Identity=32.0175438596491, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71998419, Length=228, Percent_Identity=32.0175438596491, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=314, Percent_Identity=28.6624203821656, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=319, Percent_Identity=26.3322884012539, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6319447, Length=268, Percent_Identity=29.1044776119403, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI22024126, Length=300, Percent_Identity=27.6666666666667, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21356579, Length=328, Percent_Identity=27.1341463414634, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21355201, Length=281, Percent_Identity=26.6903914590747, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668781, Length=192, Percent_Identity=30.7291666666667, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356513, Length=192, Percent_Identity=30.7291666666667, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920494, Length=150, Percent_Identity=34, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 45971; Mature: 45971

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKME
CCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FAHLAESGTGSPARRLTLLGLMQTMGRNALKPFVSPAEAAWLEHVSKIDPASLPVRIRTN
HHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECC
LPDWIQQALSTRFDAEELAQLAAALNYPAPLDLRANVLKATREQVIDALRANGIDAGETP
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FAPHGVRVVGKPALTRLKLFEEGQIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
CCCCCEEEECCHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVL
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHEE
VDAPCSGLGTLRRNPDLKWRQTRTSVDELTPKQASILASAARLVKKGGRLVYATCSVLNA
EECCCCCCHHHCCCCCCCHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHCC
ENERVVEQFLADHPDFVLVPAQKVLADQRIALETGDYLSLWPHRHATDGFFAAVLERRAA
CHHHHHHHHHHCCCCEEEECCHHHHHCCHHEEECCCEEEECCCCCCCHHHHHHHHHHHCC
Q
C
>Mature Secondary Structure
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKME
CCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FAHLAESGTGSPARRLTLLGLMQTMGRNALKPFVSPAEAAWLEHVSKIDPASLPVRIRTN
HHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECC
LPDWIQQALSTRFDAEELAQLAAALNYPAPLDLRANVLKATREQVIDALRANGIDAGETP
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FAPHGVRVVGKPALTRLKLFEEGQIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
CCCCCEEEECCHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVL
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHEE
VDAPCSGLGTLRRNPDLKWRQTRTSVDELTPKQASILASAARLVKKGGRLVYATCSVLNA
EECCCCCCHHHCCCCCCCHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHCC
ENERVVEQFLADHPDFVLVPAQKVLADQRIALETGDYLSLWPHRHATDGFFAAVLERRAA
CHHHHHHHHHHCCCCEEEECCHHHHHCCHHEEECCCEEEECCCCCCCHHHHHHHHHHHCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]