The gene/protein map for NC_010084 is currently unavailable.
Definition Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete sequence.
Accession NC_010084
Length 3,448,466

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The map label for this gene is polS [H]

Identifier: 161523879

GI number: 161523879

Start: 767906

End: 768682

Strand: Direct

Name: polS [H]

Synonym: Bmul_0699

Alternate gene names: 161523879

Gene position: 767906-768682 (Clockwise)

Preceding gene: 161523874

Following gene: 161523880

Centisome position: 22.27

GC content: 69.11

Gene sequence:

>777_bases
GTGAGACTGGAAGAGAAAGTCGCGATCCTGACGGGCGCCGCCAGCGGCATCGGCGAAGCGGTCGCGCAACGCTATCTGGA
CGAAGGCGCGCGCTGCGTGCTCGTCGACGTGAAACCGGCCGGCGGCTCGCTCGCCCGGCTCATCGAAGCGCATCCCGGCC
GCGCGGCGGCCGTCACCGCGGACGTCACGCGCCGCGACGACATCGAGCGCATCGTCGCGACCGCGGTCGAGCGGTTCGGC
GGCGTCGACATCCTGTTCAACAACGCGGCGCTGTTCGACATGCGCCCGCTCCTCGACGAATCGTGGGACGTGTTCGACCG
CCTGTTCGCGGTCAACGTGAAGGGCATGTTCTTCCTGATGCAGGCGGTCGCGCAGCGGATGGTCGAGCAGGGGCGCGGCG
GCAAGATCATCAACATGTCGTCGCAGGCCGGCCGTCGCGGCGAGGCGCTCGTCTCGCACTACTGCGCGACGAAGGCGGCC
GTGATCAGCTATACGCAGTCGGCCGCGCTCGCGCTCGCACCGCACCGGATCAACGTCAACGGCATTGCGCCGGGCGTCGT
CGACACGCCGATGTGGGAGCAGGTCGACGCACTGTTCGCGCGCTACGAGAACCGGCCGCTCGGCGAAAAGAAGCGGCTCG
TCGGCGAAGCGGTGCCGCTCGGCCGCATGGGCATGCCGGCCGATCTGACCGGCGCCGCGCTGTTTCTCGCCTCGGCCGAT
GCCGACTACATCACCGCCCAGACGCTGAACGTCGACGGCGGCAACTGGATGAGCTGA

Upstream 100 bases:

>100_bases
GCGTATCCGATCATTCGACCACTAACAGAGCAATTGTTCGGGTCGCGAGCGTTCGCTCACTTCGCGGCCGCCGTACAGCA
GAACGAACCGGAGACAACGC

Downstream 100 bases:

>100_bases
CATGAAGCCGCTTGCCTGCGCCGTCCGCCGGCCCGCTGCCGAACATCCGCGCAGCGCGCCGTGCGCGCGCGTCGCCGCGC
GAGGGCGCGGATGATGGCCG

Product: sorbitol dehydrogenase

Products: NA

Alternate protein names: L-iditol 2-dehydrogenase; Polyol dehydrogenase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MRLEEKVAILTGAASGIGEAVAQRYLDEGARCVLVDVKPAGGSLARLIEAHPGRAAAVTADVTRRDDIERIVATAVERFG
GVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLMQAVAQRMVEQGRGGKIINMSSQAGRRGEALVSHYCATKAA
VISYTQSAALALAPHRINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGMPADLTGAALFLASAD
ADYITAQTLNVDGGNWMS

Sequences:

>Translated_258_residues
MRLEEKVAILTGAASGIGEAVAQRYLDEGARCVLVDVKPAGGSLARLIEAHPGRAAAVTADVTRRDDIERIVATAVERFG
GVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLMQAVAQRMVEQGRGGKIINMSSQAGRRGEALVSHYCATKAA
VISYTQSAALALAPHRINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGMPADLTGAALFLASAD
ADYITAQTLNVDGGNWMS
>Mature_258_residues
MRLEEKVAILTGAASGIGEAVAQRYLDEGARCVLVDVKPAGGSLARLIEAHPGRAAAVTADVTRRDDIERIVATAVERFG
GVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLMQAVAQRMVEQGRGGKIINMSSQAGRRGEALVSHYCATKAA
VISYTQSAALALAPHRINVNGIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGMPADLTGAALFLASAD
ADYITAQTLNVDGGNWMS

Specific function: Catalyzes the oxidation of D-glucitol (sorbitol) to D- fructose, galactitol to D-tagatose and of L-iditol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=268, Percent_Identity=35.8208955223881, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=33.976833976834, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=34.6774193548387, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=34.8936170212766, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI10190704, Length=266, Percent_Identity=30.4511278195489, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=31.2977099236641, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=27.6923076923077, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=30.7392996108949, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=34.2412451361868, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=32.6732673267327, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4758504, Length=267, Percent_Identity=29.2134831460674, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI33667109, Length=249, Percent_Identity=32.1285140562249, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI40254992, Length=256, Percent_Identity=28.515625, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=31.4432989690722, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=32.6086956521739, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI83715985, Length=263, Percent_Identity=27.3764258555133, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=32.3699421965318, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=27.1794871794872, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI109715829, Length=198, Percent_Identity=32.3232323232323, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=29.7979797979798, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI4503817, Length=220, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI310128830, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI310115468, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4503301, Length=232, Percent_Identity=25, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=29.5336787564767, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=35.15625, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=34.7328244274809, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=33.8582677165354, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=33.0677290836653, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787335, Length=262, Percent_Identity=33.206106870229, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=32.1428571428571, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=35.3846153846154, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=29.5454545454545, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=30.2681992337165, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=32.046332046332, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=27.6264591439689, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=28.5140562248996, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=29.6703296703297, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=33.59375, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=32.0158102766798, Blast_Score=124, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17555706, Length=266, Percent_Identity=31.5789473684211, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17560220, Length=278, Percent_Identity=29.8561151079137, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17560332, Length=278, Percent_Identity=30.2158273381295, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=264, Percent_Identity=31.4393939393939, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=29.520295202952, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=31.203007518797, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562990, Length=275, Percent_Identity=28.7272727272727, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=29.1970802919708, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=276, Percent_Identity=28.6231884057971, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=28.8888888888889, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=28.7822878228782, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17563726, Length=276, Percent_Identity=28.2608695652174, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=31.3653136531365, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=30.1960784313725, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17531453, Length=278, Percent_Identity=27.6978417266187, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=31.2977099236641, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI193204405, Length=278, Percent_Identity=26.978417266187, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=28.3088235294118, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=29.0441176470588, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=27.4074074074074, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=28.7878787878788, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=29.9212598425197, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=276, Percent_Identity=28.9855072463768, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=271, Percent_Identity=27.3062730627306, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=28.4974093264249, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.6923076923077, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=257, Percent_Identity=28.0155642023346, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=217, Percent_Identity=31.3364055299539, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=267, Percent_Identity=26.5917602996255, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=26.8421052631579, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=173, Percent_Identity=26.0115606936416, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=193, Percent_Identity=26.9430051813472, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=29.4416243654822, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=25.2918287937743, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=261, Percent_Identity=28.735632183908, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=34.375, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=34.1085271317829, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=32.4324324324324, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=29.8449612403101, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=31.2977099236641, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=29.2307692307692, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=29.296875, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644337, Length=207, Percent_Identity=30.9178743961353, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=27.2388059701493, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281364892, Length=200, Percent_Identity=30, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640492, Length=189, Percent_Identity=26.984126984127, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI18859837, Length=201, Percent_Identity=30.3482587064677, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=27.9187817258883, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=28.9340101522843, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221510726, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=28.7878787878788, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581726, Length=199, Percent_Identity=27.1356783919598, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=27.4111675126904, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24665264, Length=201, Percent_Identity=25.8706467661692, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.14 [H]

Molecular weight: Translated: 27677; Mature: 27677

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MRLEEKVAILTGAASGIGEAVAQRYLDEGARCVLVDVKPAGGSLARLIEAHPGRAAAVTA
CCCHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEEE
DVTRRDDIERIVATAVERFGGVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLM
CCHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCHHHHCCHHHHHHHHHHHCHHHHHHHH
QAVAQRMVEQGRGGKIINMSSQAGRRGEALVSHYCATKAAVISYTQSAALALAPHRINVN
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEC
GIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGMPADLTGAALFLASAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHEEEEEECC
ADYITAQTLNVDGGNWMS
CCEEEEEEEECCCCCCCC
>Mature Secondary Structure
MRLEEKVAILTGAASGIGEAVAQRYLDEGARCVLVDVKPAGGSLARLIEAHPGRAAAVTA
CCCHHHEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEEE
DVTRRDDIERIVATAVERFGGVDILFNNAALFDMRPLLDESWDVFDRLFAVNVKGMFFLM
CCHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCHHHHCCHHHHHHHHHHHCHHHHHHHH
QAVAQRMVEQGRGGKIINMSSQAGRRGEALVSHYCATKAAVISYTQSAALALAPHRINVN
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEC
GIAPGVVDTPMWEQVDALFARYENRPLGEKKRLVGEAVPLGRMGMPADLTGAALFLASAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHEEEEEECC
ADYITAQTLNVDGGNWMS
CCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7551049 [H]