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The map label for this gene is rssA [H]

Identifier: 161523861

GI number: 161523861

Start: 745408

End: 746754

Strand: Direct

Name: rssA [H]

Synonym: Bmul_0681

Alternate gene names: 161523861

Gene position: 745408-746754 (Clockwise)

Preceding gene: 161523860

Following gene: 161523862

Centisome position: 21.62

GC content: 72.75

Gene sequence:

>1347_bases
GTGAGGTCGATTCGTCATCAACTGCTGATCTGGCTGCTCGCGATCGTCGTCGCGGGCGTGAGCGTCGCGGGCTGGCTGAT
CTACCGGCAGGCGCTGGCCGAGGCGAACGAACTGTTCGACTACCAGCTCCAGGAAATCGCCGCGGCGCTGCCGTCGGAGC
CGTTCTCGCAGGTGTTCGGCTCGCGCACCAACGGCGACGAAGGCATCGTGATCCAGATCTGGAATCGCAACGGCGTGCTG
ATGTACTTCTCGCATCCGCGCGCGCCGATCGCGCCGCGCGCCGAGCTTGGCTTCTCGACCGAGCGCACCGATCGCGGCGA
GTGGCGCGTGTACGGCGCAATCGTCGGCGACAACGTCGTGCAGCTCGCGCAGCCGCTGTCGGTGCGCAACCGCCTCGCGG
CGAACGTCGCGCTGCGCACGCTCTGGCCGCTGATCGTGCTGCTGCCGTTTCTCGGCGCGGCCGTCTGGATGATCGTCGGC
CGCGGGCTCGCGCCGCTCGGCCGCGTGACGCGTGCGGTCGAAACGCGCCGGCCCGAGGCGCTCGATCCGCTGCCCGACGC
GCGGCTGCCGCTCGAGGTGCAGCCGCTCGTGCGCGCGCTGAACGGGCTGCTCGCGCGGCTGTCGGGCGCGCTCGACACGC
AGAAGGCGTTCGTCGCCGATGCCGCGCACGAACTGCGCACGCCGCTCGCGGCCGTGCAGATCCAGGCGCAGCTCGTCGCC
CGCGCGAAGGACGATGCCGCGCGCCGCGAGGCGCTCGACGATCTGCAGCACGGCGTCACGCGCGCGACGCGGCTCGCCGA
GCAGCTGCTCGCGCTCGCGCGCGCCGAACCCGACGCGGGCGCGGTGCGCGAGCCGGTCGACCTGCAGACGCTGCTCGCCG
AATGCGTGGCCGCGCATGCACCGCTCGCGCAGCGGCGCAACATCGACCTCGGCTTCGAGGAAACGCGCGCGGCGACCGTC
GTCGCCGACGTCGGCGCGCTGCGCGTGATGTTCGGCAACCTGCTCGACAACGCCGTCAAGTACACGCCCGACGGCGGGCG
CATCGACGTTTCGCTGACGCGCGACGCGGCCGGCCGCGCGTGCGTGCAGATCGGCGACAGCGGCCCCGGCATTCCGGCCG
AAGAGCGCGAGCGCGTGTTCGACCGCTTCTATCGCGACAGCTCGGCGCGCGCGCGCACCGACGTGTCGGGTAGCGGGCTC
GGCCTCGCGATCGTCAAGCGTGTTGCGGCGCAGCAGGGCGCGACCGTGTCGCTCGGCGATGCGGCGGCGGGCGGCCTGCT
CGTCAGCGTCGTGTTCCGCGATGCCGAGATGCCCGCGCAGGCGCCGCAGCAGCCCGCGTCGGTGTAA

Upstream 100 bases:

>100_bases
GGTCGAGGTCTATATCCACGCACTGCGCAAGAAGCTCGGTTCGGACCTGATCCGCAACGTGCGCGGGCTCGGCTACATGG
TCGTCAAGGAAAGCTGACGC

Downstream 100 bases:

>100_bases
GGCGCGCGGCAGGCGGCTTAAGTTGCGCTTAAGGCTGATTAAGCCTCCTTTAAGTCAGCATCGTTACGCTGCGACGTAAC
AAAAGAGGAGGTCCTACGAT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRSIRHQLLIWLLAIVVAGVSVAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFGSRTNGDEGIVIQIWNRNGVL
MYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWMIVG
RGLAPLGRVTRAVETRRPEALDPLPDARLPLEVQPLVRALNGLLARLSGALDTQKAFVADAAHELRTPLAAVQIQAQLVA
RAKDDAARREALDDLQHGVTRATRLAEQLLALARAEPDAGAVREPVDLQTLLAECVAAHAPLAQRRNIDLGFEETRAATV
VADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRACVQIGDSGPGIPAEERERVFDRFYRDSSARARTDVSGSGL
GLAIVKRVAAQQGATVSLGDAAAGGLLVSVVFRDAEMPAQAPQQPASV

Sequences:

>Translated_448_residues
MRSIRHQLLIWLLAIVVAGVSVAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFGSRTNGDEGIVIQIWNRNGVL
MYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWMIVG
RGLAPLGRVTRAVETRRPEALDPLPDARLPLEVQPLVRALNGLLARLSGALDTQKAFVADAAHELRTPLAAVQIQAQLVA
RAKDDAARREALDDLQHGVTRATRLAEQLLALARAEPDAGAVREPVDLQTLLAECVAAHAPLAQRRNIDLGFEETRAATV
VADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRACVQIGDSGPGIPAEERERVFDRFYRDSSARARTDVSGSGL
GLAIVKRVAAQQGATVSLGDAAAGGLLVSVVFRDAEMPAQAPQQPASV
>Mature_448_residues
MRSIRHQLLIWLLAIVVAGVSVAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFGSRTNGDEGIVIQIWNRNGVL
MYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVVQLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWMIVG
RGLAPLGRVTRAVETRRPEALDPLPDARLPLEVQPLVRALNGLLARLSGALDTQKAFVADAAHELRTPLAAVQIQAQLVA
RAKDDAARREALDDLQHGVTRATRLAEQLLALARAEPDAGAVREPVDLQTLLAECVAAHAPLAQRRNIDLGFEETRAATV
VADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRACVQIGDSGPGIPAEERERVFDRFYRDSSARARTDVSGSGL
GLAIVKRVAAQQGATVSLGDAAAGGLLVSVVFRDAEMPAQAPQQPASV

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=450, Percent_Identity=30.6666666666667, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786783, Length=347, Percent_Identity=28.2420749279539, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790551, Length=272, Percent_Identity=31.25, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=32.6086956521739, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=31.9672131147541, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790861, Length=295, Percent_Identity=31.864406779661, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788279, Length=317, Percent_Identity=26.1829652996845, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787374, Length=292, Percent_Identity=27.0547945205479, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=27.8260869565217, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=28.6919831223629, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI48994928, Length=215, Percent_Identity=24.6511627906977, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=30.8016877637131, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082128, Length=253, Percent_Identity=28.0632411067194, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=264, Percent_Identity=26.1363636363636, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=212, Percent_Identity=26.4150943396226, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=28.8793103448276, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=25.5230125523013, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=209, Percent_Identity=28.2296650717703, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=205, Percent_Identity=26.3414634146341, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48176; Mature: 48176

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIRHQLLIWLLAIVVAGVSVAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
SRTNGDEGIVIQIWNRNGVLMYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVV
CCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEEEEECCCHHH
QLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWMIVGRGLAPLGRVTRAVETRRPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
LDPLPDARLPLEVQPLVRALNGLLARLSGALDTQKAFVADAAHELRTPLAAVQIQAQLVA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RAKDDAARREALDDLQHGVTRATRLAEQLLALARAEPDAGAVREPVDLQTLLAECVAAHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
PLAQRRNIDLGFEETRAATVVADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRA
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCE
CVQIGDSGPGIPAEERERVFDRFYRDSSARARTDVSGSGLGLAIVKRVAAQQGATVSLGD
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCC
AAAGGLLVSVVFRDAEMPAQAPQQPASV
HHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRSIRHQLLIWLLAIVVAGVSVAGWLIYRQALAEANELFDYQLQEIAAALPSEPFSQVFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
SRTNGDEGIVIQIWNRNGVLMYFSHPRAPIAPRAELGFSTERTDRGEWRVYGAIVGDNVV
CCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEEEEECCCHHH
QLAQPLSVRNRLAANVALRTLWPLIVLLPFLGAAVWMIVGRGLAPLGRVTRAVETRRPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
LDPLPDARLPLEVQPLVRALNGLLARLSGALDTQKAFVADAAHELRTPLAAVQIQAQLVA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RAKDDAARREALDDLQHGVTRATRLAEQLLALARAEPDAGAVREPVDLQTLLAECVAAHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
PLAQRRNIDLGFEETRAATVVADVGALRVMFGNLLDNAVKYTPDGGRIDVSLTRDAAGRA
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCE
CVQIGDSGPGIPAEERERVFDRFYRDSSARARTDVSGSGLGLAIVKRVAAQQGATVSLGD
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCC
AAAGGLLVSVVFRDAEMPAQAPQQPASV
HHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA