Click here to switch to the map view.

The map label for this gene is ctaC [H]

Identifier: 161523636

GI number: 161523636

Start: 498813

End: 500411

Strand: Direct

Name: ctaC [H]

Synonym: Bmul_0456

Alternate gene names: 161523636

Gene position: 498813-500411 (Clockwise)

Preceding gene: 161523635

Following gene: 161523637

Centisome position: 14.46

GC content: 64.73

Gene sequence:

>1599_bases
ATGGAAATTTTGGGTAAGGATGCTATGAAAACAATCAAGCGAGCCCTCACGGGCGTGCTGGCATGCAGCGGATTGCTCTT
TGCCGGTGCCGCTCTGGCGGTCGGTGACAGCCCGGGCGGCCCCCGCGTCAACGAGATCAACCTGCAGCCGCCCGTCACGA
AGATCGCCGAGGAGCTCTACGATCTCCACACGATGATGCTGATCCTCTGTACGGTGATCTTCGTCGGCGTGTTCGGCGTG
ATGTTCTATTCGATCTTCGCGCACCGCAAATCCAAGGGCCACAAGGCCGCCAATTTCCATGAAAGCACGACCGTCGAAAT
CATCTGGACGATCGTGCCGTTCATCATCGTCGTGCTGATGGCGCTGCCGGCCACGAAGGCCGTCGTCGCGATGAAGGACA
CGACCAACGCCGACCTGACGATCAAGGTCACCGGTTATCAGTGGAAGTGGGGTTACGACTACGTGAAGGGCCCGGGCGAG
GGCATCAGCTTCCTGTCGACGCTCACGACCCCGCGCGACGAAGTGATGGGCAAGAAGCCGATCACCGAAACCTATCTGCA
GGAAGTCGACAACCCGCTCGTCGTGCCGGTCAACAAGAAGATCCGCATCATCACGACCGCGAACGACGTCGTGCACTCGT
GGTACGTGCCCGCGTTCGGCGTGAAGCAGGATGCGATTCCGGGCTTCGTGCGCGACACCTGGTTCAAGGCCGACAAGGTC
GGCACGTTCCGCGGCTTCTGTACCGAACTGTGCGGCAAGGAGCACGCGTACATGCCGGTCGTCGTCGAAGTGCTGTCGGA
CGACGACTACGCGAAGTGGGTCAGCGCGCAGAAGGCGAAGCTCGCCGGCGCGGCAGTCGATCCGAACAAGGTCTATACGA
TGGCCGAACTCGTCTCGCACGGCGAGGAAGTCTACAAGGCGAACTGCGCGGCATGCCACCAGGTGAACGGCAAGGGCCTC
GGCGCCTTCCCGGCGATGGACGGCAGCCCGATCGTGAACGGCCCGATCGCCGGCCACCTCGAGCGCGTGCTGCACGGCAA
GGGCGCGATGCCGTCGTGGGCATCGCTGTCGGATCTCGACATCGCGTCGGTCATCACGTACGAGCGCAATTCGTGGGGTA
ACCACAAGAACGATCTGCTGCAGCCGAAGCAAGTGGCCGACGCGCGCAACGGCAAGATGCCGGAAGACACCGCGGGTGGC
GCAGCGACCGCATCGGCACCGGCCGAAGCGGCTTCGGCGCCGGCGCAGGCCGCGTCGGGCGCAGCGCAACAGCCGGCGGC
ATCGGCTGCGCTGTCGACGATCTACTTCGAGACGGGCAAGAGCGCGCTGCCGGCCGACGCGAAAGCGGCGATCGCCGCAG
CGGCCGACTATGCGAACGCGCATCCGGACGCGAAGCTCGCGCTGTCGGGCTTCACCGACAAGACGGGCTCGGCCGACGCG
AACGCCGAACTGGCCAAGCATCGGGCACAGGCCGTGCGCGACGCGCTGAAGGCGGCGGGCGTGGCGGAAGACCGCATCAT
TCTCAAAAAGCCGGAAACGATCACGGGCGGGGCAGACGCGAAGGAAGCCCGGCGGGTCGAGATCGGGCCGGCGGCTTGA

Upstream 100 bases:

>100_bases
GCAGTTCGCCGACGAACTGCGCGTAGCGCTCCGGCGCTGCGGCTGATGAAGCGCTCGTCGGGAGGCAACCGCAGGCGGCT
TGCGACGGGGGAGGGTTTGA

Downstream 100 bases:

>100_bases
CGTGTCGCTGAGTTTGTCGACGTATTCGCATTAGGAGATTCTCATGTCTAGCATCGGGCACGACGTAGCCGCGGGCCACG
CGCACGACGACCACGCGCAC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLMALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGE
GISFLSTLTTPRDEVMGKKPITETYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAGAAVDPNKVYTMAELVSHGEEVYKANCAACHQVNGKGL
GAFPAMDGSPIVNGPIAGHLERVLHGKGAMPSWASLSDLDIASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDTAGG
AATASAPAEAASAPAQAASGAAQQPAASAALSTIYFETGKSALPADAKAAIAAAADYANAHPDAKLALSGFTDKTGSADA
NAELAKHRAQAVRDALKAAGVAEDRIILKKPETITGGADAKEARRVEIGPAA

Sequences:

>Translated_532_residues
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLMALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGE
GISFLSTLTTPRDEVMGKKPITETYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAGAAVDPNKVYTMAELVSHGEEVYKANCAACHQVNGKGL
GAFPAMDGSPIVNGPIAGHLERVLHGKGAMPSWASLSDLDIASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDTAGG
AATASAPAEAASAPAQAASGAAQQPAASAALSTIYFETGKSALPADAKAAIAAAADYANAHPDAKLALSGFTDKTGSADA
NAELAKHRAQAVRDALKAAGVAEDRIILKKPETITGGADAKEARRVEIGPAA
>Mature_532_residues
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLMALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGE
GISFLSTLTTPRDEVMGKKPITETYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAGAAVDPNKVYTMAELVSHGEEVYKANCAACHQVNGKGL
GAFPAMDGSPIVNGPIAGHLERVLHGKGAMPSWASLSDLDIASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDTAGG
AATASAPAEAASAPAQAASGAAQQPAASAALSTIYFETGKSALPADAKAAIAAAADYANAHPDAKLALSGFTDKTGSADA
NAELAKHRAQAVRDALKAAGVAEDRIILKKPETITGGADAKEARRVEIGPAA

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=221, Percent_Identity=34.841628959276, Blast_Score=136, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6226540, Length=233, Percent_Identity=31.3304721030043, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 56328; Mature: 56328

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTKIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCCEEECCCCCHHHHHHHHH
DLHTMMLILCTVIFVGVFGVMFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGEGISFLSTLTTPRDEVMGKKP
HCCCCCEEEEEECCCCCCEEEEEECEEEECCCCCCCCCCCHHHHHHHHCCCHHHHCCCCC
ITETYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
CHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAGAAVDPNKVYTMAELVSH
CHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GEEVYKANCAACHQVNGKGLGAFPAMDGSPIVNGPIAGHLERVLHGKGAMPSWASLSDLD
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
IASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDTAGGAATASAPAEAASAPAQAASG
HHHHEEECCCCCCCCCHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCC
AAQQPAASAALSTIYFETGKSALPADAKAAIAAAADYANAHPDAKLALSGFTDKTGSADA
CCCCCHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
NAELAKHRAQAVRDALKAAGVAEDRIILKKPETITGGADAKEARRVEIGPAA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINLQPPVTKIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCCEEECCCCCHHHHHHHHH
DLHTMMLILCTVIFVGVFGVMFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFIIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGEGISFLSTLTTPRDEVMGKKP
HCCCCCEEEEEECCCCCCEEEEEECEEEECCCCCCCCCCCHHHHHHHHCCCHHHHCCCCC
ITETYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
CHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVSAQKAKLAGAAVDPNKVYTMAELVSH
CHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHC
GEEVYKANCAACHQVNGKGLGAFPAMDGSPIVNGPIAGHLERVLHGKGAMPSWASLSDLD
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
IASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDTAGGAATASAPAEAASAPAQAASG
HHHHEEECCCCCCCCCHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCC
AAQQPAASAALSTIYFETGKSALPADAKAAIAAAADYANAHPDAKLALSGFTDKTGSADA
CCCCCHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
NAELAKHRAQAVRDALKAAGVAEDRIILKKPETITGGADAKEARRVEIGPAA
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1648008 [H]