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The map label for this gene is ctaD [H]

Identifier: 161523637

GI number: 161523637

Start: 500455

End: 502062

Strand: Direct

Name: ctaD [H]

Synonym: Bmul_0457

Alternate gene names: 161523637

Gene position: 500455-502062 (Clockwise)

Preceding gene: 161523636

Following gene: 161523638

Centisome position: 14.51

GC content: 64.49

Gene sequence:

>1608_bases
ATGTCTAGCATCGGGCACGACGTAGCCGCGGGCCACGCGCACGACGACCACGCGCACGAAACGCCGCACGGCTGGCGGCG
CTGGCTGTTCGCCACCAACCACAAGGACATCGGTACGCTGTACCTGCTGTTCTCGTTCATCATGTTCCTGTCGGGCGGCG
TGATGGCGCTCGGCATCCGCGCCGAGCTGTTCCAGCCCGGCCTGCAGATCATGCGTCCGGAGTTCTTCAACGAACTCACG
ACGATGCACGGCCTGATCATGGTGTTCGGCGCGATCATGCCGGCGTTCGTCGGCTTCGCGAACTGGATGATTCCGCTGCA
GATCGGCGCGTCCGACATGGCGTTCGCGCGGATGAACAACTTCAGCTTCTGGCTGCTGCCGGTCGCGGCGGTGCTGCTGG
TCGGCTCGTTCTTCGCGCCGGGCGGCGCGACGGCCGCGGGCTGGACGCTCTACGCGCCGCTGTCGACGCAGATGGGCCCG
GGCATGGACTTCGCGATCTTCGCGGTGCACATCATGGGCGCGTCGTCGATCATGGGCGGCATCAACATCGTCGTGACGAT
CCTGAACATGCGCGCGCCGGGCATGACGCTGATGAAGATGCCGATGTTCGCATGGACCTGGCTGATCACCGCGTATCTGC
TGATCGCCGTGATGCCGGTTCTGGCGGGCGCGATCACGATGGTGCTGTTCGACCGTCACTTCGGCACGTCGTTCTTCAAC
GCGGCAGGCGGCGGCGACCCGGTCATGTACCAGCACATCTTCTGGTTCTTCGGCCACCCCGAGGTGTACATCATGATTCT
GCCGGCGTTCGGGATCGTGTCGCAGGTGATCCCGGCGTTCTCGCGCAAGACGCTGTTCGGCTATAGCTCGATGGTGTACG
CGACGGCCTCGATCGCGATCCTGTCGTTCATGGTCTGGGCGCACCACATGTTCGCGACCGGCATGCCGGTCACCGGCCAG
CTGTTCTTCATGTACGCGACGATGCTGATCGCGGTGCCGACCGGCGTGAAGGTGTTCAACTGGCTCGCGACGATGTGGCG
CGGTTCGATGACGTTCGAAACGCCGATGCTGTTCGCGATCGGCTTCCTGTTCGTGTTCACGTTCGGCGGCCTGACGGGCC
TGATGCTCGCGATGGCGCCGCTCGACATCCAGTATCACGGCACCTACTTCGTGGTCGCGCACTTCCACTACGTGCTGGTC
GCGGGGTCGCTGTTCGCGCTGTTCTCGGGCTGGTACTACTGGTCGCCGAAGTGGACGGGCTGGATGTACAACGAGACGCG
CGGCAAGATCCACTTCTGGGCGTCGATGATCTTCTTCAACCTGACGTTCTTCCCGATGCACTTCGTCGGTCTCGCGGGCA
TGCCGCGCCGCTATGCGGACTACCCGGCGCAGTTCACGGACTTCAACCAGGTCGCGACGATCGGCGCATTCGGCTTCGGC
CTCGCGCAGGTGTACTTCCTGTTCGCGGTCGTGCTGCCGGCCTACCGTGGCGGCGGCGAGCTGGAGAAGGCGTCGGACAA
GCCGTGGGACGGCGCGACCGGCCTCGAATGGACGGTGCCGAGCCCGGCTCCGTTCCACACGTTCGAGCAACCGCCGCACG
TCGAATAA

Upstream 100 bases:

>100_bases
ACGGGCGGGGCAGACGCGAAGGAAGCCCGGCGGGTCGAGATCGGGCCGGCGGCTTGACGTGTCGCTGAGTTTGTCGACGT
ATTCGCATTAGGAGATTCTC

Downstream 100 bases:

>100_bases
GTTTCACCGCGCGTTCCGCCGCTGCCTGCCGCGCAGGCAGGCGCGGCGGACGCCCGAACCGAAGTATCAGATGACCCGGA
ATCCACAACAAAGACGTACG

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MSSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIRAELFQPGLQIMRPEFFNELT
TMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGP
GMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFSRKTLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTGQ
LFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAIGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLV
AGSLFALFSGWYYWSPKWTGWMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
LAQVYFLFAVVLPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE

Sequences:

>Translated_535_residues
MSSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIRAELFQPGLQIMRPEFFNELT
TMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGP
GMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFSRKTLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTGQ
LFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAIGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLV
AGSLFALFSGWYYWSPKWTGWMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
LAQVYFLFAVVLPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE
>Mature_534_residues
SSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIRAELFQPGLQIMRPEFFNELTT
MHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPG
MDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFNA
AGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFSRKTLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTGQL
FFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAIGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVA
GSLFALFSGWYYWSPKWTGWMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFGL
AQVYFLFAVVLPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=515, Percent_Identity=49.126213592233, Blast_Score=461, Evalue=1e-130,
Organism=Escherichia coli, GI1786634, Length=521, Percent_Identity=41.0748560460653, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=48.0225988700565, Blast_Score=487, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=50.4643962848297, Blast_Score=329, Evalue=8e-91,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=46.9635627530364, Blast_Score=216, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59509; Mature: 59377

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIR
CCCCCCCHHCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHH
AELFQPGLQIMRPEFFNELTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNN
HHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCC
FSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIMGG
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
INIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
HHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFSRKTLFGYSSMVYATASIAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFSGWYYWSPKWTG
HHHHHHHHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHHHCCEEEECCCCCC
WMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LAQVYFLFAVVLPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSIGHDVAAGHAHDDHAHETPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALGIR
CCCCCCHHCCCCCCCCCCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHH
AELFQPGLQIMRPEFFNELTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNN
HHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCC
FSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIMGG
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
INIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
HHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFSRKTLFGYSSMVYATASIAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFSGWYYWSPKWTG
HHHHHHHHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHHHCCEEEECCCCCC
WMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LAQVYFLFAVVLPAYRGGGELEKASDKPWDGATGLEWTVPSPAPFHTFEQPPHVE
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]