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The map label for this gene is aroB [H]

Identifier: 161523476

GI number: 161523476

Start: 323454

End: 324533

Strand: Direct

Name: aroB [H]

Synonym: Bmul_0296

Alternate gene names: 161523476

Gene position: 323454-324533 (Clockwise)

Preceding gene: 161523475

Following gene: 161523477

Centisome position: 9.38

GC content: 67.96

Gene sequence:

>1080_bases
ATGATTACTGTCAACGTCGATCTGGGCGACCGCGCCTACCCGATTCACATTGGCGCCGGCCTGATCGGCCGCGCCGAGCT
GTTCGCTCCCCACATCAAAGGTTCGTCGGTGACGGTCGTCACGAACACGACGGTCGATCCGCTTTACGGCGACGCGCTGC
GCGCGGCGCTCGCGCCGCTCGGCAAGCACGTGTCGACGGTCGTGCTGCCCGACGGCGAAGCCTACAAGAACTGGGAAACG
CTGAACCTCATTTTCGACGGGCTGCTCGGCGAGCGCGCCGATCGCAAGACGACGCTCGTTGCACTCGGCGGCGGCGTGAT
CGGCGACATGACGGGCTTTGCCGCCGCCTGCTACATGCGCGGCGTGCCGTTCATCCAGGTGCCGACCACGCTGCTGTCGC
AGGTCGATTCGTCGGTCGGCGGCAAGACGGGCATCAATCATCCGCTCGGCAAGAACATGATCGGCGCGTTTTACCAGCCG
CAGGCGGTGATCGCCGACATCGGCGCGCTGACGACGCTGCCCGAGCGCGAGCTCGCGGCCGGCATCGCCGAGGTCATCAA
GACCGGCGCGATCGCCGATGCCGCATTCTTCGACTGGATCGAGGCGAACGTCGACGCGCTGAACCGGCGCGATCCCGCGG
CGCTCGCGCACGCGGTGAAGCGGTCGTGCGAGATCAAGGCGAGCGTCGTCGCGGCCGACGAGCGCGAGGGCGGCTTGCGC
GCGATCCTCAATTTCGGACATACGTTCGGCCACGCGATCGAGGCGGGCCTCGGCTACGGCGAATGGCTGCACGGCGAGGC
GGTCGGCTGCGGGATGGTGATGGCAGCCGATCTGTCGGTGCGGCTCGGGCTGCTCGACGACGCGTCGCGGCAGCGGCTCG
ACGCGGTGATCGCGGCCGCGCATCTGCCGACGCGCGGGCCGGCGCTCGGCGACGCGCGCTACATGGAACTGATGCGCGTC
GACAAGAAGGCCGAAGCCGGCGCGATCAAGTTCATCTTGCTGAAGCGCTTCGGCGATACGCTGATCACGCAGGCGCCCGA
CGAAGCGGTGTTCGCTACACTGGCGCACACGACCCGGTAA

Upstream 100 bases:

>100_bases
ACTTCGTGATCGAAACGGGCCGCCCGTCCGTGAACGGTCTCGTCAACATGGTGCTGATGCAACTCGAACTGGCGGGCGTC
GTCGCCAAGCCGCTACAAGC

Downstream 100 bases:

>100_bases
TCGCGCCCCGGACGCCCGGCGCCCCTGACATGGAGGAGACGTGAGCGAGACATCCAGCCGCCATCTGCCCGAAACCGGCC
GTGGCCCAGCCGCCGCCGTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTVVTNTTVDPLYGDALRAALAPLGKHVSTVVLPDGEAYKNWET
LNLIFDGLLGERADRKTTLVALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALTTLPERELAAGIAEVIKTGAIADAAFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGLLDDASRQRLDAVIAAAHLPTRGPALGDARYMELMRV
DKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAHTTR

Sequences:

>Translated_359_residues
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTVVTNTTVDPLYGDALRAALAPLGKHVSTVVLPDGEAYKNWET
LNLIFDGLLGERADRKTTLVALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALTTLPERELAAGIAEVIKTGAIADAAFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGLLDDASRQRLDAVIAAAHLPTRGPALGDARYMELMRV
DKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAHTTR
>Mature_359_residues
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTVVTNTTVDPLYGDALRAALAPLGKHVSTVVLPDGEAYKNWET
LNLIFDGLLGERADRKTTLVALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALTTLPERELAAGIAEVIKTGAIADAAFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGLLDDASRQRLDAVIAAAHLPTRGPALGDARYMELMRV
DKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAHTTR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=334, Percent_Identity=58.6826347305389, Blast_Score=368, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6320332, Length=371, Percent_Identity=39.0835579514825, Blast_Score=219, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 37842; Mature: 37842

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTVVTNTTVDPLYGDALRAALAPL
CEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
GKHVSTVVLPDGEAYKNWETLNLIFDGLLGERADRKTTLVALGGGVIGDMTGFAAACYMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALTTLPERELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHH
GIAEVIKTGAIADAAFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
HHHHHHHHCCHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGLLDDASRQRLDAVIAAA
HHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHHHH
HLPTRGPALGDARYMELMRVDKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAHTTR
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MITVNVDLGDRAYPIHIGAGLIGRAELFAPHIKGSSVTVVTNTTVDPLYGDALRAALAPL
CEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
GKHVSTVVLPDGEAYKNWETLNLIFDGLLGERADRKTTLVALGGGVIGDMTGFAAACYMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALTTLPERELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHH
GIAEVIKTGAIADAAFFDWIEANVDALNRRDPAALAHAVKRSCEIKASVVAADEREGGLR
HHHHHHHHCCHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRLGLLDDASRQRLDAVIAAA
HHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHHHH
HLPTRGPALGDARYMELMRVDKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAHTTR
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA