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The map label for this gene is putA [H]

Identifier: 161523294

GI number: 161523294

Start: 121323

End: 125255

Strand: Direct

Name: putA [H]

Synonym: Bmul_0114

Alternate gene names: 161523294

Gene position: 121323-125255 (Clockwise)

Preceding gene: 161523293

Following gene: 161523295

Centisome position: 3.52

GC content: 69.54

Gene sequence:

>3933_bases
ATGGCAAGCACGACCCTCGGCGTCAAAGTCGACGACCTTCTCCGCTCACGTCTGAAAGATGCGGCCACGCGTCTCGAACG
CACGCCTCACTGGCTCATCAAGCAGGCGATCTTCGCGTATCTGGAGCGGATCGAGCACGGCCAGCTGCCGCCCGAGCTGT
CGGGCCACAGCGGCGTCGCGGATCTTGCCGACGGGCACGCGACGGACGGCGAGGACGACAACTCGCCGCACCCGTTCCTC
GAGTTCGCGCAGAACGTGCAGCCGCAGTCGGTGCTGCGCGCGGCGATCACGGCCGCGTATCGCCGGCCCGAGCCGGAGTG
CGTGCCGTTCCTGATCGGCCAGGCGCGCCTGCCCGCGAATCTGCAGGCCGACGTGCAGTCGCTCGCGACCCGGCTCGTCG
AGGCGCTGCGCGAGAAGAGCTCCGGCGGCGGCGTCGAAGGGCTGATCCACGAGTTCTCGTTGTCGAGCCAGGAAGGCGTC
GCGCTGATGTGCCTCGCCGAAGCGCTTCTGCGCATCCCCGATCGCGCGACGCGCGACGCGCTGATCCGCGACAAGATCAG
CAAGGGCGACTGGCGCTCGCACGTCGGGCACGCGCCGTCGCTGTTCGTGAACGCGGCGACGTGGGGCCTGATGATCACCG
GCAAGCTCGTGACGACGAACAGCGAAGCGGGGCTGTCGTCCGCGCTCACGCGCCTGATCGGCCGCGGCGGCGAGCCGCTG
ATCCGCAAGGGCGTCGACATGGCGATGCGCCTGATGGGCGAGCAGTTCGTCACCGGCGAGACGATTTCCGAAGCGCTCGC
GAACAGCCGCAAGTACGAAGCGCGCGGCTTCCGCTACTCGTACGACATGCTCGGCGAAGCGGCGACGACCGAAGAGGATG
CGCAGCGCTACTACGCGTCGTACGAGCAGGCGATCCACGCGATCGGCAAGGCGGCCGGCGGCCGCGGCATCTACGAAGGG
CCGGGCATCTCGATCAAGCTGTCCGCGCTGCATCCGCGCTATTCGCGTTCGCAGCAGGAACGCACGATGACCGAGCTGCT
GCCGCGCGTGCGCGCACTGGCGCTGCTCGCGCGCCGCTACGACATCGGCCTGAACATCGACGCGGAAGAGGCCGATCGTC
TCGAACTGTCGCTCGACCTGCTCGAGGCGCTGTGCTTCGATCCCGATCTCGCGGGCTGGAACGGAATCGGTTTCGTCGTG
CAGGGCTACCAGAAGCGCTGCCCGTTCGTGATCGACTATCTGATCGACCTCGCGCGCCGCAGCCGTCATCGTCTGATGAT
CCGCCTCGTGAAGGGCGCGTACTGGGATACCGAAATCAAGCGTGCTCAGGTCGACGGCCTCGAGGGCTATCCCGTCTATA
CGCGCAAGATCTACACGGACGTGTCGTATCTCGCGTGTGCGAAGAAGCTGCTCGCGGCGCCCGATGCCGTGTATCCGCAG
TTCGCGACGCACAACGCGTACACGCTCGCCGCGATCTATCACCTGGCCGGCCAGAACTACTACCCGGGCCAGTACGAATT
CCAGTGCCTGCACGGCATGGGCGAGCCGCTGTACGAGGAAGTCACGGGCCGCGACAAGCTGAACCGCCCGTGCCGCGTGT
ACGCGCCGGTCGGCACGCACGAGACGCTGCTCGCCTACCTCGTGCGCCGTCTGCTCGAGAACGGCGCGAACACGTCGTTC
GTGAACCGCATCGCCGACAAATCGGTCTCGGTGAAGGAACTGGTCGCCGATCCGGTCGACGAGGCATCGAAGGTCGTGCC
GCTCGGCGCGCCGCATCCGAAGATTCCGCTGCCGCGCAACCTGTACGGCGACGAGCGTCCCAACTCGATGGGCCTCGACC
TGTCGAACGAGCATCGTCTCGCGTCGCTGTCGTCCGCGCTGCTCGCAAGCGCGCATCATCCGTGGCGCGCAGCGCCGATG
CTTGCCGACGACGCGCTCGCCGACGCGCCGGCGCGCGACGTACGCAATCCGGCCGACCAGCGCGACATCGTCGGCACGGT
CAGCGAAGCGACGGCCGAGCACGTGAGCGCGGCGCTCGCGCATGCGGTCACGGCCGCGCCGATCTGGCAGGCGACGCCGG
TCGATGCGCGCGCCGACTGCCTCGTGCGCGCGGCCGATCTGCTCGAAGCGCAGATGCACACGCTGATGGGCCTGATCGTG
CGCGAAGCCGGCAAGTCGCTGCCGAACGCGATCGCGGAAATCCGCGAAGCGGTCGACTTCCTGCGCTACTACGCGGCGCA
GATCCGCGGCGAATTCTCGAACGATACGCATCGTCCGCTCGGCCCGGTCGTCTGCATCAGCCCGTGGAACTTCCCGCTCG
CGATCTTCATGGGCCAGGTCGCCGCCGCGCTCGCGGCCGGCAACACGGTGCTCGCGAAGCCCGCGGAGCAGACGCCGCTG
ATCGCCGCGCAGGCCGTGCGGCTGCTGCGCGAGGCCGGCGTGCCGGCCGGCGCGGTGCAGCTGCTGCCGGGCGACGGCGA
GACGGTCGGCGCCGCGCTCGTTGCCGATCCGCGCACGCGCGCGGTGATGTTCACGGGTTCGACCGAGGTCGCGCGCCTGA
TCAACAAGACGCTGTCCACGCGCCTCGATCCGGACGGCAAGCCGATTCCGCTGATCGCCGAAACGGGCGGCCAGAACGCG
ATGATCGTCGACTCGTCGGCGCTCGCGGAACAGGTCATCGCGGACGTGATGCAGTCGTCGTTCGACTCGGCCGGTCAACG
CTGTTCGGCGCTGCGCGTTCTGTGTCTGCAGGACGACGTCGCCGACCGCACGCTGACGATGCTCAAGGGCGCGATGCAGG
AACTGTCGCTCGGCAACCCGGACCGTCTGTCGACCGACGTCGGCCCGGTGATCGACGCGGACGCGAAGCGCACGATCGAC
GCGCATATCGCGACGATGAAGGACAAGGGCCATGCGGTCACGCAGCTCGCGATGCCGGAAGCATGCGCGCACGGCACGTT
CGTGCCGCCGACGCTGATCGAGATCGGCAGCATCGACGAACTGAAGCGCGAAGTGTTCGGCCCCGTGCTGCACGTCGTGC
GCTATCGCCGCAGCCAGCTCGACAAGCTGCTCGAGCAGATCCGCGCGACGGGCTACGGCCTCACGCTCGGCATCCATACG
CGGATCGACGAGACGATCGCGCACGTGATCTCGCGCGCGCACGTCGGCAACATCTACGTGAACCGCAACGTGATCGGCGC
GGTGGTCGGCGTGCAGCCGTTCGGCGGCGAAGGGCTGTCCGGTACGGGGCCGAAGGCCGGCGGCGCGCTGTATCTGCAGC
GTCTGCTCGCGACGCGTCCGTCGGGCCTGCCGCGTTCGCTCGCGCAGTCGCTCGTCGCGGACGGCGCGGCCGAAGGCGGC
GAGCGTGCGCACCCGGCGGCGGCGCTCACGGCGCTGCGCGACTGGCTGATCGAGCAACGCGAGCCGGCGCTGGCCGCGCG
CTGCGACGGCTACCTCGCGCAGGTGCCGGCCGGCGCGACCGCCGTGCTGACGGGGCCGACGGGCGAGCGAAACACGTATA
CACTCGGCCCGCGCGGCACGGTGCTGTGCGTCGCGGCGACGCCGTCCGGCGCACGTGCGCAGCTCGCGGCGGTGCTCGCG
ACCGGCAACCGCGCGCTGTTCTCGGGCGCGGCCGGCGAGGCGCTGGTCGCCGCGCTGCCCGCCTCGCTGAAGGCGCATGC
GACGGTGCGCAAGCAGGCCGACGCGGCGTTCGACGCGGTGCTGTTCGAAGGCGACAGCGACGAACTGCTGACGCTCGTGA
AGGAAGTCGCGCAGCGGCCGGGCCCGATCGTGTCGGTGCAGGGCGTGTCCGCGGGCGCGTTCGAGCACGGCGACGCGGAG
GACTACGCGCTCGAGCGGCTGCTGACCGAGCGCTCGGTCAGCGTGAATACGGCCGCGGCGGGCGGCAATGCGAATTTGAT
GACGATCGGCTGA

Upstream 100 bases:

>100_bases
CCGTCTTGAAATTCGGTTGCACCTTTTTATTGCGTGCCGTAGGATTTCGCGCATCCTCTCACACCACATTGCCGGCTTTG
CGCCGGCGCATGAACCCACC

Downstream 100 bases:

>100_bases
CCATCCTTGCCGCTCGGCTCAAACAATGGAAGCGGCAAGGCGATCCCGAAGCCGCTCCACTTACCCTGGTACCTAGGAGA
TGCTATGCAACACACGATGA

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1310; Mature: 1309

Protein sequence:

>1310_residues
MASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVADLADGHATDGEDDNSPHPFL
EFAQNVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPANLQADVQSLATRLVEALREKSSGGGVEGLIHEFSLSSQEGV
ALMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEG
PGISIKLSALHPRYSRSQQERTMTELLPRVRALALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVV
QGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQ
FATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSF
VNRIADKSVSVKELVADPVDEASKVVPLGAPHPKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPM
LADDALADAPARDVRNPADQRDIVGTVSEATAEHVSAALAHAVTAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
REAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPL
IAAQAVRLLREAGVPAGAVQLLPGDGETVGAALVADPRTRAVMFTGSTEVARLINKTLSTRLDPDGKPIPLIAETGGQNA
MIVDSSALAEQVIADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMQELSLGNPDRLSTDVGPVIDADAKRTID
AHIATMKDKGHAVTQLAMPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHT
RIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRSLAQSLVADGAAEGG
ERAHPAAALTALRDWLIEQREPALAARCDGYLAQVPAGATAVLTGPTGERNTYTLGPRGTVLCVAATPSGARAQLAAVLA
TGNRALFSGAAGEALVAALPASLKAHATVRKQADAAFDAVLFEGDSDELLTLVKEVAQRPGPIVSVQGVSAGAFEHGDAE
DYALERLLTERSVSVNTAAAGGNANLMTIG

Sequences:

>Translated_1310_residues
MASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVADLADGHATDGEDDNSPHPFL
EFAQNVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPANLQADVQSLATRLVEALREKSSGGGVEGLIHEFSLSSQEGV
ALMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEG
PGISIKLSALHPRYSRSQQERTMTELLPRVRALALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVV
QGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQ
FATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSF
VNRIADKSVSVKELVADPVDEASKVVPLGAPHPKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPM
LADDALADAPARDVRNPADQRDIVGTVSEATAEHVSAALAHAVTAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
REAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPL
IAAQAVRLLREAGVPAGAVQLLPGDGETVGAALVADPRTRAVMFTGSTEVARLINKTLSTRLDPDGKPIPLIAETGGQNA
MIVDSSALAEQVIADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMQELSLGNPDRLSTDVGPVIDADAKRTID
AHIATMKDKGHAVTQLAMPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHT
RIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRSLAQSLVADGAAEGG
ERAHPAAALTALRDWLIEQREPALAARCDGYLAQVPAGATAVLTGPTGERNTYTLGPRGTVLCVAATPSGARAQLAAVLA
TGNRALFSGAAGEALVAALPASLKAHATVRKQADAAFDAVLFEGDSDELLTLVKEVAQRPGPIVSVQGVSAGAFEHGDAE
DYALERLLTERSVSVNTAAAGGNANLMTIG
>Mature_1309_residues
ASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVADLADGHATDGEDDNSPHPFLE
FAQNVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPANLQADVQSLATRLVEALREKSSGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPLI
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHPRYSRSQQERTMTELLPRVRALALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVVQ
GYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
ATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADKSVSVKELVADPVDEASKVVPLGAPHPKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPML
ADDALADAPARDVRNPADQRDIVGTVSEATAEHVSAALAHAVTAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIVR
EAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRLLREAGVPAGAVQLLPGDGETVGAALVADPRTRAVMFTGSTEVARLINKTLSTRLDPDGKPIPLIAETGGQNAM
IVDSSALAEQVIADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMQELSLGNPDRLSTDVGPVIDADAKRTIDA
HIATMKDKGHAVTQLAMPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHTR
IDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRSLAQSLVADGAAEGGE
RAHPAAALTALRDWLIEQREPALAARCDGYLAQVPAGATAVLTGPTGERNTYTLGPRGTVLCVAATPSGARAQLAAVLAT
GNRALFSGAAGEALVAALPASLKAHATVRKQADAAFDAVLFEGDSDELLTLVKEVAQRPGPIVSVQGVSAGAFEHGDAED
YALERLLTERSVSVNTAAAGGNANLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=453, Percent_Identity=32.0088300220751, Blast_Score=186, Evalue=2e-46,
Organism=Homo sapiens, GI153266822, Length=449, Percent_Identity=30.0668151447661, Blast_Score=177, Evalue=6e-44,
Organism=Homo sapiens, GI25777732, Length=447, Percent_Identity=30.8724832214765, Blast_Score=171, Evalue=4e-42,
Organism=Homo sapiens, GI25777736, Length=466, Percent_Identity=30.4721030042918, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI25777734, Length=466, Percent_Identity=30.4721030042918, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI238859541, Length=466, Percent_Identity=30.4721030042918, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI25777730, Length=444, Percent_Identity=30.4054054054054, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI25777724, Length=452, Percent_Identity=28.9823008849558, Blast_Score=166, Evalue=2e-40,
Organism=Homo sapiens, GI21614513, Length=426, Percent_Identity=29.3427230046948, Blast_Score=160, Evalue=1e-38,
Organism=Homo sapiens, GI25777728, Length=406, Percent_Identity=29.8029556650246, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI238814322, Length=423, Percent_Identity=27.4231678486998, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI12007648, Length=444, Percent_Identity=28.3783783783784, Blast_Score=150, Evalue=9e-36,
Organism=Homo sapiens, GI4507229, Length=496, Percent_Identity=28.6290322580645, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI25777721, Length=509, Percent_Identity=27.7013752455796, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI115387104, Length=449, Percent_Identity=26.5033407572383, Blast_Score=138, Evalue=3e-32,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=27.7647058823529, Blast_Score=137, Evalue=1e-31,
Organism=Homo sapiens, GI310128093, Length=461, Percent_Identity=26.2472885032538, Blast_Score=131, Evalue=5e-30,
Organism=Homo sapiens, GI188035924, Length=463, Percent_Identity=25.7019438444924, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI310128103, Length=463, Percent_Identity=25.7019438444924, Blast_Score=130, Evalue=7e-30,
Organism=Homo sapiens, GI25952152, Length=438, Percent_Identity=28.0821917808219, Blast_Score=127, Evalue=7e-29,
Organism=Homo sapiens, GI25777726, Length=452, Percent_Identity=25.2212389380531, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI310128091, Length=396, Percent_Identity=26.2626262626263, Blast_Score=114, Evalue=6e-25,
Organism=Homo sapiens, GI310128087, Length=457, Percent_Identity=24.0700218818381, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI71773324, Length=385, Percent_Identity=24.9350649350649, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI4502043, Length=329, Percent_Identity=24.6200607902736, Blast_Score=94, Evalue=9e-19,
Organism=Homo sapiens, GI238814371, Length=329, Percent_Identity=24.6200607902736, Blast_Score=94, Evalue=9e-19,
Organism=Homo sapiens, GI206597441, Length=459, Percent_Identity=24.1830065359477, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI206597439, Length=459, Percent_Identity=24.1830065359477, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI22907049, Length=459, Percent_Identity=24.1830065359477, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI310128089, Length=336, Percent_Identity=25, Blast_Score=85, Evalue=6e-16,
Organism=Homo sapiens, GI73695881, Length=353, Percent_Identity=22.9461756373938, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI73695879, Length=353, Percent_Identity=22.9461756373938, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI310128101, Length=223, Percent_Identity=27.3542600896861, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI310128095, Length=322, Percent_Identity=25.4658385093168, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI310128099, Length=222, Percent_Identity=27.4774774774775, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI301500698, Length=432, Percent_Identity=23.8425925925926, Blast_Score=77, Evalue=2e-13,
Organism=Homo sapiens, GI4557303, Length=334, Percent_Identity=22.4550898203593, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI73466520, Length=334, Percent_Identity=22.4550898203593, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI310128097, Length=269, Percent_Identity=24.907063197026, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1787250, Length=1333, Percent_Identity=66.6166541635409, Blast_Score=1722, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=462, Percent_Identity=30.7359307359307, Blast_Score=182, Evalue=1e-46,
Organism=Escherichia coli, GI1787715, Length=447, Percent_Identity=32.4384787472036, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1787684, Length=460, Percent_Identity=29.5652173913043, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI1788042, Length=448, Percent_Identity=30.5803571428571, Blast_Score=157, Evalue=5e-39,
Organism=Escherichia coli, GI1787558, Length=411, Percent_Identity=31.1435523114355, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI87081896, Length=413, Percent_Identity=29.7820823244552, Blast_Score=146, Evalue=7e-36,
Organism=Escherichia coli, GI1786504, Length=475, Percent_Identity=28.4210526315789, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI87082295, Length=449, Percent_Identity=28.5077951002227, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI87081926, Length=442, Percent_Identity=26.0180995475113, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1787653, Length=261, Percent_Identity=24.5210727969349, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=461, Percent_Identity=32.3210412147505, Blast_Score=191, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI25144435, Length=454, Percent_Identity=32.15859030837, Blast_Score=174, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32564736, Length=410, Percent_Identity=32.9268292682927, Blast_Score=166, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=493, Percent_Identity=29.4117647058824, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=375, Percent_Identity=33.0666666666667, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI115534176, Length=461, Percent_Identity=28.8503253796095, Blast_Score=156, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI25143874, Length=511, Percent_Identity=26.2230919765166, Blast_Score=150, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI32564151, Length=412, Percent_Identity=30.3398058252427, Blast_Score=150, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI25143876, Length=512, Percent_Identity=26.3671875, Blast_Score=149, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI133930964, Length=437, Percent_Identity=28.1464530892449, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=453, Percent_Identity=26.7108167770419, Blast_Score=134, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17534119, Length=454, Percent_Identity=27.0925110132159, Blast_Score=131, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71995606, Length=443, Percent_Identity=26.410835214447, Blast_Score=126, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71995613, Length=400, Percent_Identity=26, Blast_Score=121, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=30.1324503311258, Blast_Score=117, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI25146391, Length=326, Percent_Identity=25.7668711656442, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=326, Percent_Identity=25.7668711656442, Blast_Score=96, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=326, Percent_Identity=25.7668711656442, Blast_Score=96, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=330, Percent_Identity=25.4545454545455, Blast_Score=91, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320917, Length=458, Percent_Identity=32.5327510917031, Blast_Score=193, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6325196, Length=464, Percent_Identity=31.4655172413793, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6321826, Length=478, Percent_Identity=30.1255230125523, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324950, Length=450, Percent_Identity=28.2222222222222, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6323821, Length=470, Percent_Identity=30.6382978723404, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323822, Length=474, Percent_Identity=29.535864978903, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6319478, Length=465, Percent_Identity=27.741935483871, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321828, Length=374, Percent_Identity=26.4705882352941, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323757, Length=326, Percent_Identity=26.3803680981595, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129399, Length=446, Percent_Identity=30.4932735426009, Blast_Score=169, Evalue=9e-42,
Organism=Drosophila melanogaster, GI281362580, Length=471, Percent_Identity=28.6624203821656, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI62472918, Length=471, Percent_Identity=28.6624203821656, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI62472926, Length=471, Percent_Identity=28.6624203821656, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI62472936, Length=471, Percent_Identity=28.6624203821656, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21356737, Length=471, Percent_Identity=28.6624203821656, Blast_Score=169, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24668425, Length=481, Percent_Identity=26.4033264033264, Blast_Score=163, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24668417, Length=481, Percent_Identity=26.4033264033264, Blast_Score=163, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24668413, Length=481, Percent_Identity=26.4033264033264, Blast_Score=163, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24650465, Length=448, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24585660, Length=474, Percent_Identity=26.5822784810127, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28574525, Length=493, Percent_Identity=26.7748478701826, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24666674, Length=452, Percent_Identity=28.7610619469027, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571806, Length=459, Percent_Identity=25.2723311546841, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571802, Length=459, Percent_Identity=25.2723311546841, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571800, Length=459, Percent_Identity=25.2723311546841, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571798, Length=459, Percent_Identity=25.2723311546841, Blast_Score=137, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28571796, Length=459, Percent_Identity=25.2723311546841, Blast_Score=137, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28571794, Length=459, Percent_Identity=25.2723311546841, Blast_Score=137, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24638878, Length=428, Percent_Identity=26.8691588785047, Blast_Score=116, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24638876, Length=428, Percent_Identity=26.8691588785047, Blast_Score=116, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281360299, Length=335, Percent_Identity=27.7611940298507, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281360297, Length=335, Percent_Identity=27.7611940298507, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281360295, Length=335, Percent_Identity=27.7611940298507, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24586250, Length=335, Percent_Identity=27.7611940298507, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281360301, Length=331, Percent_Identity=27.190332326284, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281360303, Length=331, Percent_Identity=25.9818731117825, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45552499, Length=335, Percent_Identity=25.9701492537313, Blast_Score=93, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 140458; Mature: 140326

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
DLADGHATDGEDDNSPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPAN
HHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCC
LQADVQSLATRLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
HHHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHH
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYAS
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHH
YEQAIHAIGKAAGGRGIYEGPGISIKLSALHPRYSRSQQERTMTELLPRVRALALLARRY
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVVQGYQKRCPFVIDYLIDLARR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEECHHHCCCHHHHHHHHHHHH
SRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQ
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTH
HHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRIADKSVSVKELVADPVDEASKVVPLGAPHPKIPLPRN
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCHHHHHCEEECCCCCCCCCCCCC
LYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLADDALADAPARDVRNPADQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHCCCCCH
RDIVGTVSEATAEHVSAALAHAVTAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
AAALAAGNTVLAKPAEQTPLIAAQAVRLLREAGVPAGAVQLLPGDGETVGAALVADPRTR
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCC
AVMFTGSTEVARLINKTLSTRLDPDGKPIPLIAETGGQNAMIVDSSALAEQVIADVMQSS
EEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
FDSAGQRCSALRVLCLQDDVADRTLTMLKGAMQELSLGNPDRLSTDVGPVIDADAKRTID
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
AHIATMKDKGHAVTQLAMPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQL
HHHHHHCCCCCHHHHHHCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DKLLEQIRATGYGLTLGIHTRIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLS
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCC
GTGPKAGGALYLQRLLATRPSGLPRSLAQSLVADGAAEGGERAHPAAALTALRDWLIEQR
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
EPALAARCDGYLAQVPAGATAVLTGPTGERNTYTLGPRGTVLCVAATPSGARAQLAAVLA
CCHHHHHHCCHHHCCCCCCEEEEECCCCCCCCEEECCCCCEEEEEECCCCCHHHHHHHHC
TGNRALFSGAAGEALVAALPASLKAHATVRKQADAAFDAVLFEGDSDELLTLVKEVAQRP
CCCHHEECCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCC
GPIVSVQGVSAGAFEHGDAEDYALERLLTERSVSVNTAAAGGNANLMTIG
CCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC
>Mature Secondary Structure 
ASTTLGVKVDDLLRSRLKDAATRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVA
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
DLADGHATDGEDDNSPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLIGQARLPAN
HHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCC
LQADVQSLATRLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
HHHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHH
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYAS
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHH
YEQAIHAIGKAAGGRGIYEGPGISIKLSALHPRYSRSQQERTMTELLPRVRALALLARRY
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGLNIDAEEADRLELSLDLLEALCFDPDLAGWNGIGFVVQGYQKRCPFVIDYLIDLARR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEECHHHCCCHHHHHHHHHHHH
SRHRLMIRLVKGAYWDTEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQ
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTH
HHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRIADKSVSVKELVADPVDEASKVVPLGAPHPKIPLPRN
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCHHHHHCEEECCCCCCCCCCCCC
LYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLADDALADAPARDVRNPADQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHCCCCCH
RDIVGTVSEATAEHVSAALAHAVTAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
AAALAAGNTVLAKPAEQTPLIAAQAVRLLREAGVPAGAVQLLPGDGETVGAALVADPRTR
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCC
AVMFTGSTEVARLINKTLSTRLDPDGKPIPLIAETGGQNAMIVDSSALAEQVIADVMQSS
EEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
FDSAGQRCSALRVLCLQDDVADRTLTMLKGAMQELSLGNPDRLSTDVGPVIDADAKRTID
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
AHIATMKDKGHAVTQLAMPEACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQL
HHHHHHCCCCCHHHHHHCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DKLLEQIRATGYGLTLGIHTRIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLS
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCC
GTGPKAGGALYLQRLLATRPSGLPRSLAQSLVADGAAEGGERAHPAAALTALRDWLIEQR
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
EPALAARCDGYLAQVPAGATAVLTGPTGERNTYTLGPRGTVLCVAATPSGARAQLAAVLA
CCHHHHHHCCHHHCCCCCCEEEEECCCCCCCCEEECCCCCEEEEEECCCCCHHHHHHHHC
TGNRALFSGAAGEALVAALPASLKAHATVRKQADAAFDAVLFEGDSDELLTLVKEVAQRP
CCCHHEECCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCC
GPIVSVQGVSAGAFEHGDAEDYALERLLTERSVSVNTAAAGGNANLMTIG
CCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]