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The map label for this gene is pheC [H]

Identifier: 161523291

GI number: 161523291

Start: 116239

End: 117015

Strand: Reverse

Name: pheC [H]

Synonym: Bmul_0111

Alternate gene names: 161523291

Gene position: 117015-116239 (Counterclockwise)

Preceding gene: 161523296

Following gene: 161523290

Centisome position: 3.39

GC content: 64.61

Gene sequence:

>777_bases
ATGAAGACACTCGCCACGATCGCCGCGGCCGCGATGCTGTGCTGCGCCGGCGCCGCGCAGGCGGAAGGCGCCGGCGCTTC
CCGACTCGACGACGTGCTCGCGCGCGGCACGCTGCGCGTCTGCACGACCGGCGACTACAAGCCGTATTCGTACTACCGCA
CGGACGGCCGCTTCGAGGGCATCGACATCGACATGGCCGAATCGCTCGCGAAATCGCTCGGCGTGAAGCCCGACTACGTG
AAGACGAGCTGGTCGAACCTGACCGCCGACTTCGTCGCGAAGTGCGACATCGCGGTCGGCGGCGTATCGACGACGCTCGA
ACGGCAGAAGCGCGCGTTCTTCACGCAGCCGTACGTCGTCGACGGGAAGACGCCGATCGTGCGCTGCGGCGACGTCGACA
AATATCAGACGGTCGCGCAAATCGACCGCCCCGAAACGCGCGTGATCGTGAACCCCGGCGGCACGAACGAGCGTTTCGCG
AAGCAGTATTTCACGCACGCGAACCTGACGGTCTATCCCGACAACGTGACGATCTTCAAGCAGATCCTCGCGGGCAAGGC
CGACGTGATGGTAACGGACGCGTCCGAGACGCTGCTGCAGCAAAAGCTGAATCCGGGCCTCTGCTCGGTGCACCCGGACA
AGCCGTTCCAGTTCGGCGAGAAGGCGTACATGGTGCCGCGCGGCGACGTCGTGTTCCAGCAGTACGTCGATCAGTGGCTG
CACCTCGCGCTGTCGACGGGCGAATACCAGGCGATCTCCGATAAATGGCTCAAGTAA

Upstream 100 bases:

>100_bases
CGCTCCGACTGCGCGTGCCCGTGCGATGGCGGCCATATGACGCGCGCGATGGCTCCGTTATGATCGGACGCTCATATCGA
ACCGAACCAGGAGGAGACAG

Downstream 100 bases:

>100_bases
CGGCATGATCGACGGCGATGCGCGCGCTTCGGCTCACGCGCTTCGCTTCGCGCGTCGGCCGCCGCGCGCGCGTTTGCATT
CACCTCGCCGATCGCCCGCG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKTLATIAAAAMLCCAGAAQAEGAGASRLDDVLARGTLRVCTTGDYKPYSYYRTDGRFEGIDIDMAESLAKSLGVKPDYV
KTSWSNLTADFVAKCDIAVGGVSTTLERQKRAFFTQPYVVDGKTPIVRCGDVDKYQTVAQIDRPETRVIVNPGGTNERFA
KQYFTHANLTVYPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVVFQQYVDQWL
HLALSTGEYQAISDKWLK

Sequences:

>Translated_258_residues
MKTLATIAAAAMLCCAGAAQAEGAGASRLDDVLARGTLRVCTTGDYKPYSYYRTDGRFEGIDIDMAESLAKSLGVKPDYV
KTSWSNLTADFVAKCDIAVGGVSTTLERQKRAFFTQPYVVDGKTPIVRCGDVDKYQTVAQIDRPETRVIVNPGGTNERFA
KQYFTHANLTVYPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVVFQQYVDQWL
HLALSTGEYQAISDKWLK
>Mature_258_residues
MKTLATIAAAAMLCCAGAAQAEGAGASRLDDVLARGTLRVCTTGDYKPYSYYRTDGRFEGIDIDMAESLAKSLGVKPDYV
KTSWSNLTADFVAKCDIAVGGVSTTLERQKRAFFTQPYVVDGKTPIVRCGDVDKYQTVAQIDRPETRVIVNPGGTNERFA
KQYFTHANLTVYPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVVFQQYVDQWL
HLALSTGEYQAISDKWLK

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=255, Percent_Identity=27.0588235294118, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787088, Length=231, Percent_Identity=25.1082251082251, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 28403; Mature: 28403

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLATIAAAAMLCCAGAAQAEGAGASRLDDVLARGTLRVCTTGDYKPYSYYRTDGRFEG
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCEEEECCCEECC
IDIDMAESLAKSLGVKPDYVKTSWSNLTADFVAKCDIAVGGVSTTLERQKRAFFTQPYVV
CCCHHHHHHHHHHCCCCCCEECCHHHCCHHHHHCCCEEECCHHHHHHHHHHHHCCCCEEE
DGKTPIVRCGDVDKYQTVAQIDRPETRVIVNPGGTNERFAKQYFTHANLTVYPDNVTIFK
CCCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEECCCHHHHH
QILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVVFQQYVDQWL
HHHCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
HLALSTGEYQAISDKWLK
HHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MKTLATIAAAAMLCCAGAAQAEGAGASRLDDVLARGTLRVCTTGDYKPYSYYRTDGRFEG
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCEEEECCCEECC
IDIDMAESLAKSLGVKPDYVKTSWSNLTADFVAKCDIAVGGVSTTLERQKRAFFTQPYVV
CCCHHHHHHHHHHCCCCCCEECCHHHCCHHHHHCCCEEECCHHHHHHHHHHHHCCCCEEE
DGKTPIVRCGDVDKYQTVAQIDRPETRVIVNPGGTNERFAKQYFTHANLTVYPDNVTIFK
CCCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEECCCHHHHH
QILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVVFQQYVDQWL
HHHCCCCCEEEECHHHHHHHHHCCCCCEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
HLALSTGEYQAISDKWLK
HHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]