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The map label for this gene is argC [H]

Identifier: 161508448

GI number: 161508448

Start: 214552

End: 215586

Strand: Reverse

Name: argC [H]

Synonym: USA300HOU_0197

Alternate gene names: 161508448

Gene position: 215586-214552 (Counterclockwise)

Preceding gene: 161508449

Following gene: 161508447

Centisome position: 7.5

GC content: 35.46

Gene sequence:

>1035_bases
ATGATGATTAAAGTAGGTATCGTTGGCGGTAGCGGTTATGGCGCAATTGAATTAATTCGATTGTTACAAACACATCCTCA
TGTAACGATTGCACACATCTACTCACATTCAAAAGTAGATGAACCGTTGAAATTAACATTTCCACATTTACAACATATTA
TGCAACATTTCGAAGCACTTACAGTGGACAATAATGACTGTGATGTAATTTTCTTTGCGACACCAGCACCCGTAAGTAAA
ACATGTATCCCTCCCTTAGTAGAAAAAGGTATTCATGTTATCGATTTATCTGGCGCATTTAGAATTAAGAATCGTGAAAT
ATATGAAGCATATTACAAAGAAACTGCTGCAGCACAAGATGATTTGAATCATGCTATTTACAGCATTTCAGAATGGCAAT
CGTTTGATAACAATGGAACGAAGCTCATTTCTAATCCTGGCTGTTTCCCTACAGCAACATTATTAGCATTACATCCACTT
ATTAGCGAAAAAATAGTAGATTTGTCATCTATTATTATTGATGCTAAGACCGGCGTGTCAGGTGCTGGTCGTTCATTATC
ACAACGTGTTCATTTTTCAGAAATGAATGAAAATCTAAGCGCTTATGCAATCGGAAACCATAAACACAAACCGGAAATCG
AGCAATATTTATCTATCATTGCGGGTCAAGATGTATCAGTCATATTTACACCACATCTCGTACCAATGACACGAGGTATT
TTATCAACAATATATGTCAAATTATCATCTGAATATACGACTGAATCATTACATAAATTAATGACCTCTTATTATGCTAA
TCAGCCATTTGTCAGAATTAGAGATATTGGGACTTTTCCAACCACAAAAGAAGTACTCGGTAGTAACTACTGCGATATCG
GCATCTATGTAGATGAAACAACGCAAACAGCAATTTTAGTATCAGTGATTGATAACCTTGTCAAAGGCGCAAGTGGGCAA
GCCATTCAAAATTTAAATATATTATATGATTTTGAAGTGACGACTGGCCTAAATCAATCACCAGTTTATCCATAA

Upstream 100 bases:

>100_bases
TAGTCATTGATAAAGAGGAAATCCATCAAATTGTTGCAGCTTTTCAAGACGTTTTTAAAAATTAACAATTAATCATTTAT
ATATGACATAGGAGGGATTC

Downstream 100 bases:

>100_bases
GGGGTGTTAGAATGAAACATCAAGAAACGACATCACAACAATATAACTTTTCAATTATTAAACATGGCGATATCAGTACA
CCTCAAGGCTTCACGGCTGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MMIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEALTVDNNDCDVIFFATPAPVSK
TCIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQDDLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPL
ISEKIVDLSSIIIDAKTGVSGAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGI
LSTIYVKLSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDETTQTAILVSVIDNLVKGASGQ
AIQNLNILYDFEVTTGLNQSPVYP

Sequences:

>Translated_344_residues
MMIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEALTVDNNDCDVIFFATPAPVSK
TCIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQDDLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPL
ISEKIVDLSSIIIDAKTGVSGAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGI
LSTIYVKLSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDETTQTAILVSVIDNLVKGASGQ
AIQNLNILYDFEVTTGLNQSPVYP
>Mature_344_residues
MMIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEALTVDNNDCDVIFFATPAPVSK
TCIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQDDLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPL
ISEKIVDLSSIIIDAKTGVSGAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGI
LSTIYVKLSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDETTQTAILVSVIDNLVKGASGQ
AIQNLNILYDFEVTTGLNQSPVYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=344, Percent_Identity=38.0813953488372, Blast_Score=205, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6320913, Length=353, Percent_Identity=24.929178470255, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 38022; Mature: 38022

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS01224 ARGC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEAL
CEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECHHHHHHHHHHHEE
TVDNNDCDVIFFATPAPVSKTCIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQD
EECCCCCCEEEEECCCCCCCCCCCHHHHCCCEEEEECCEEEECCHHHHHHHHHHHHHHHH
DLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLISEKIVDLSSIIIDAKTGVS
HHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
GAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGI
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHH
LSTIYVKLSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDET
HHHHEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCEEEEEEEECC
TQTAILVSVIDNLVKGASGQAIQNLNILYDFEVTTGLNQSPVYP
CCHHHHHHHHHHHHCCCCCCEEECCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MMIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEAL
CEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECHHHHHHHHHHHEE
TVDNNDCDVIFFATPAPVSKTCIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQD
EECCCCCCEEEEECCCCCCCCCCCHHHHCCCEEEEECCEEEECCHHHHHHHHHHHHHHHH
DLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLISEKIVDLSSIIIDAKTGVS
HHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
GAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGI
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHH
LSTIYVKLSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDET
HHHHEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCEEEEEEEECC
TQTAILVSVIDNLVKGASGQAIQNLNILYDFEVTTGLNQSPVYP
CCHHHHHHHHHHHHCCCCCCEEECCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA