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The map label for this gene is argD [H]

Identifier: 161508449

GI number: 161508449

Start: 215622

End: 216833

Strand: Reverse

Name: argD [H]

Synonym: USA300HOU_0198

Alternate gene names: 161508449

Gene position: 216833-215622 (Counterclockwise)

Preceding gene: 161508450

Following gene: 161508448

Centisome position: 7.55

GC content: 37.79

Gene sequence:

>1212_bases
ATGTATAAATATAAAGGAGGGAGACCGATGAATTCAATCATTGAATTAACTGATTATTATAGCTCTAATAATTATGCACC
ACTTAAGCTTGTCATTTCTAAAGGTAAAGGTGTCAAAGTTTGGGATACTGATGGCAAACAATATATAGATTGCATTTCGG
GTTTTTCAGTTGCAAACCAAGGCCATTGTCATCCAACAATTGTTAAAGCGATGACAGAACAAGCTTCAAAGTTGTCTATC
ATTTCACGTGTCCTTTATAGTGACAATCTCGGGAAATGGGAAGAAAAAATTTGTCATCTTGCTAAGAAAGACAAAGTACT
CCCCCTTAACTCTGGTACTGAAGCTGTTGAAGCAGCCATTAAAATTGCTAGAAAATGGGGCTCTGAAGTTAAAGGCATTA
CTGACGGACAAGTTGAAATCATCGCTATGAATAACAATTTTCACGGTCGTACACTTGGCTCATTATCACTATCTAACCAC
GACGCATATAAAGCAGGATTTCACCCCCTACTTCAAGGCACTACAACAGTAGATTTTGGAGACATTGAACAATTAACACA
AGCTATTTCACCGAATACAGCAGCAATTATTTTGGAACCAATTCAAGGTGAAGGTGGCGTTAATATACCACCGAAAGGAT
ATATTCAAGCTGTGCGTCAACTATGTGATAAACATCAAATATTATTGATTGCAGATGAAATTCAAGTTGGTCTTGGTAGA
ACTGGGAAATGGTTTGCTATGGAATGGGAGCAAGTCGTTCCAGACATTTATATTTTAGGTAAGGCATTGGGTGGCGGCTT
ATACCCTGTATCTGCTGTACTTGCAAATAATGATGTCATGCGTGTTCTAACACCAGGTACACATGGTTCAACATTTGGTG
GTAACCCTTTAGCCATTGCAATATCGACGGCAGCGCTTGATGTACTTAAAGATGAACAACTGGTTGAACGATCAGAACGC
TTAGGTTCATTTTTATTAAAAGCGTTGCTACAACTTAAACATCCTAGTATTAAAGAAATTAGAGGTCGTGGTTTATTTAT
AGGCATAGAGCTTAACACAGATGCTGCACCTTTTGTGGATCAACTGATTCAACGTGGAATCTTATGCAAAGACACGCATC
GTACTATCATTCGATTGTCTCCACCTCTAGTCATTGATAAAGAGGAAATCCATCAAATTGTTGCAGCTTTTCAAGACGTT
TTTAAAAATTAA

Upstream 100 bases:

>100_bases
AAATCACATTAATACAAACACAACCTTATCTTTATATTATTAAATTTACATTTGACACTTATATTGAACAACTGTAATAT
ATTAATATTAATTCTTTAAA

Downstream 100 bases:

>100_bases
CAATTAATCATTTATATATGACATAGGAGGGATTCATGATGATTAAAGTAGGTATCGTTGGCGGTAGCGGTTATGGCGCA
ATTGAATTAATTCGATTGTT

Product: ornithine aminotransferase

Products: NA

Alternate protein names: OAT 1; Ornithine--oxo-acid aminotransferase 1 [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MYKYKGGRPMNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQGHCHPTIVKAMTEQASKLSI
ISRVLYSDNLGKWEEKICHLAKKDKVLPLNSGTEAVEAAIKIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNH
DAYKAGFHPLLQGTTTVDFGDIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILLIADEIQVGLGR
TGKWFAMEWEQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIAISTAALDVLKDEQLVERSER
LGSFLLKALLQLKHPSIKEIRGRGLFIGIELNTDAAPFVDQLIQRGILCKDTHRTIIRLSPPLVIDKEEIHQIVAAFQDV
FKN

Sequences:

>Translated_403_residues
MYKYKGGRPMNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQGHCHPTIVKAMTEQASKLSI
ISRVLYSDNLGKWEEKICHLAKKDKVLPLNSGTEAVEAAIKIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNH
DAYKAGFHPLLQGTTTVDFGDIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILLIADEIQVGLGR
TGKWFAMEWEQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIAISTAALDVLKDEQLVERSER
LGSFLLKALLQLKHPSIKEIRGRGLFIGIELNTDAAPFVDQLIQRGILCKDTHRTIIRLSPPLVIDKEEIHQIVAAFQDV
FKN
>Mature_403_residues
MYKYKGGRPMNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQGHCHPTIVKAMTEQASKLSI
ISRVLYSDNLGKWEEKICHLAKKDKVLPLNSGTEAVEAAIKIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNH
DAYKAGFHPLLQGTTTVDFGDIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILLIADEIQVGLGR
TGKWFAMEWEQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIAISTAALDVLKDEQLVERSER
LGSFLLKALLQLKHPSIKEIRGRGLFIGIELNTDAAPFVDQLIQRGILCKDTHRTIIRLSPPLVIDKEEIHQIVAAFQDV
FKN

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=389, Percent_Identity=45.7583547557841, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI284507298, Length=289, Percent_Identity=46.7128027681661, Blast_Score=271, Evalue=1e-72,
Organism=Homo sapiens, GI24119277, Length=419, Percent_Identity=31.0262529832936, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI37574042, Length=406, Percent_Identity=30.5418719211823, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI13994255, Length=453, Percent_Identity=28.476821192053, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI226442709, Length=372, Percent_Identity=30.1075268817204, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI226442705, Length=411, Percent_Identity=29.1970802919708, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=23.4192037470726, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=23.4192037470726, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=23.4192037470726, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI145693181, Length=372, Percent_Identity=39.5161290322581, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1789759, Length=381, Percent_Identity=36.2204724409449, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1788044, Length=379, Percent_Identity=37.7308707124011, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=35.1898734177215, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1789016, Length=407, Percent_Identity=32.4324324324324, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1786991, Length=409, Percent_Identity=29.3398533007335, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1786349, Length=321, Percent_Identity=31.7757009345794, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=393, Percent_Identity=44.7837150127226, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI25144274, Length=395, Percent_Identity=36.7088607594937, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI32564660, Length=421, Percent_Identity=30.166270783848, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI71981843, Length=181, Percent_Identity=40.8839779005525, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=29.1375291375291, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17541228, Length=413, Percent_Identity=27.1186440677966, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6323470, Length=399, Percent_Identity=43.859649122807, Blast_Score=330, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6324432, Length=403, Percent_Identity=33.4987593052109, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=436, Percent_Identity=27.2935779816514, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=375, Percent_Identity=26.6666666666667, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=47.8835978835979, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI161085790, Length=433, Percent_Identity=27.9445727482679, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28574759, Length=416, Percent_Identity=28.6057692307692, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI21356575, Length=428, Percent_Identity=29.4392523364486, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=26.2295081967213, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=26.2295081967213, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=26.2295081967213, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 44131; Mature: 44131

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKYKGGRPMNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQ
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCC
GHCHPTIVKAMTEQASKLSIISRVLYSDNLGKWEEKICHLAKKDKVLPLNSGTEAVEAAI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHH
KIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKAGFHPLLQGTTTVDFG
HHHHHHCHHCCCCCCCCEEEEEECCCCCCCEECEEECCCCCCHHHCCHHHHCCCCEECCC
DIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILLIADEIQVGLGR
CHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCC
TGKWFAMEWEQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIA
CCCEEEEEHHHHCCHHEEEHHHHCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEE
ISTAALDVLKDEQLVERSERLGSFLLKALLQLKHPSIKEIRGRGLFIGIELNTDAAPFVD
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCHHHH
QLIQRGILCKDTHRTIIRLSPPLVIDKEEIHQIVAAFQDVFKN
HHHHCCCEEECCCCEEEEECCCEEECHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYKYKGGRPMNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCISGFSVANQ
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHCCCCCCC
GHCHPTIVKAMTEQASKLSIISRVLYSDNLGKWEEKICHLAKKDKVLPLNSGTEAVEAAI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCHHHHHHHH
KIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKAGFHPLLQGTTTVDFG
HHHHHHCHHCCCCCCCCEEEEEECCCCCCCEECEEECCCCCCHHHCCHHHHCCCCEECCC
DIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQILLIADEIQVGLGR
CHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCC
TGKWFAMEWEQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTPGTHGSTFGGNPLAIA
CCCEEEEEHHHHCCHHEEEHHHHCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEE
ISTAALDVLKDEQLVERSERLGSFLLKALLQLKHPSIKEIRGRGLFIGIELNTDAAPFVD
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCCCHHHH
QLIQRGILCKDTHRTIIRLSPPLVIDKEEIHQIVAAFQDVFKN
HHHHCCCEEECCCCEEEEECCCEEECHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA