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The map label for this gene is copB [H]

Identifier: 160903304

GI number: 160903304

Start: 2071315

End: 2073357

Strand: Direct

Name: copB [H]

Synonym: Pmob_1874

Alternate gene names: 160903304

Gene position: 2071315-2073357 (Clockwise)

Preceding gene: 160903303

Following gene: 160903314

Centisome position: 95.47

GC content: 42.29

Gene sequence:

>2043_bases
ATGAAACACAGAAACCGTCAAACGAAACATAATATGAATGCCGAGCACACAAATCATACCGATGGTGGTGGGCATGCCTC
ACATCACGCACACATGGTGGCTGATTTCAGGAAGAGGTTCTGGGTATCATTAATTGTGACTATCCCCGTTCTTCTACTTT
CTCCACTTATCCAATCTTTTTTCGGCTATTCCATAGATTTTGCGGGTTCGATGTTTTTTCTTTTTGGCCTTTCTTCATTT
GTCTATTTCTACGGTGGCTGGCCGTTTTTAGAGGGACTGTTTCAGGAGTTAAAAAAGAAACAACCCGGTATGATGACGCT
CATTGCGCTGGCTATATCTGTCGCCTATTTTTACAGTAGTGCGGTTGTCTTTGGAGTTGAAGGAAAAGTATTCTTTTGGG
AATTAGTTACCCTTATAGATATTATGCTCCTTGGACACTGGATAGAGATGAAATCTATTATGGGAGCGTCACAGGCTTTG
GAGGAACTGGCGAAACTTATGCCGTCAGAAGCCCATCGTCTAAAAGAAAGTGGAGATATAGAAGAGGTCAAGATTGAAGA
TTTGCAATCACAGGATAAAGTGCTTATCAAACCGGGTGAAAAAATTCCGGTTGACGGAATAGTTCTCGAAGGCGAATCGG
ATGTTGATGAATCTGCTATAACTGGTGAATCAAAGCCGGTAAGCAAAAAAAAGGATGATAAGGTTATCGGTGGCGCAGTC
AACGGAGAAGGTTCTCTCACTGTCCAAGTAACCAAGACCGGCAAAGATTCTTATCTTTCCCAAGTGATAGAGTTAGTAAG
GATTGCCAGTGAAAGTAAATCTAGGGCGCAAGGATTAGCGGATAAGGCGGCTTTCTGGTTGACAATAATTGCTATTACGG
CAGGTGCAGCAACCCTTATAACCTGGCTTGTATTAGGTAAAGAATTTGTATTTGCTTTGGAACGTATGGTTACTGTCATG
GTTATTACTTGCCCGCACGCCTTAGGCCTGGCTATACCACTTGTTATCGCTGTAATTACATCTATTTCGGCTAAGAACGG
CCTTCTGATTAGGAATAGAACTTCTTTTGAAGGTGCTCGTAATATTGATGTTGTCGTTTTTGATAAAACAGGTACATTAA
CCAAAGGGGAATTCGGGGTATCGGACATTGTTACGTTTGGCGGCTGGAAGGAAGACGAGCTTTTACGTGATGTCGCTGCC
ATTGAAACAAATTCCGAACACACGATTGCCAAAGGAATCGTGAAAAAAGCAAAAGAAAAGAAGCTGGATTTACCTAAGGT
AGAAAATTTCTCAAGTCTGCCAGGGAAAGGCGCTAAAGCGCGTATTCAGGGCAAACAAATTTTTGTTGGAAATAAAGGGA
TTTTTGAAATTGCCGAAGTATCTTCAACGGACGATGCGCAAAAACAGGCTAACGAGTTTGCTTCTCAGGGAAAGACACTG
GTCTTTGTTGCTTCAGAAAACAAGATTCAGGGGATCATCGCTCTCTCAGATATCATCAGAGATGAATCAAAAGAAGCGAT
TAAGAGACTCAAAAAGCAAGATATAAGTGTTTCGATGATTACTGGCGATAATCAGGCAACCGCTAAATTTGTAGCCGATC
AATTAGGCTTGGACAGTTTTTTTGCCGAAGTTTTGCCCGATAAAAAATCCGAGAAAATAAAAAAACTTCAAAGCGAAGGT
AGAAAAGTTGCGATGGTGGGTGATGGTGTCAATGATGCGCCTGCTCTGGCTCAGGCTGACGTGGGAATAGCCATAGGGGC
AGGTACGGATGTAGCTGTTGAAACAGCCGATGTGGTATTGATCGAGAATGATCCCAGAAATGTATTGGATATCATCCGGC
TCTCGGCAATTAATCATCGCAAAACTGTCCAAAATCTTGCTTGGGCTACAGGCTATAACGTGTTTGCCATACCTCTAGCG
GCCGGGGTCTTGTATAGTTATGGAATTATTCTCGCTCCAGCTATGGGGGCTATTATCATGTCCCTTAGTACAGTAATTGT
CGCGATTAATTCTAGACTGATAAAATTTCAAAAGGAATACTAA

Upstream 100 bases:

>100_bases
AGGTTAGAAAGAATGGATTGACACATTATTTCTGTAGTAAACTCTGTAAGGATGAATTTATTAAAACAGGCTACTAGTCT
GAAAAGGAGGTTAATAATCT

Downstream 100 bases:

>100_bases
CATGAAAGCACATGTTGATCGAGATGGGTGATGGGAAAGCCCAATTGCACACAAACCTGTCCTGAAGTGTTTCAACTGGA
AGAAGGAAAATCAAAAGTCA

Product: heavy metal translocating P-type ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MKHRNRQTKHNMNAEHTNHTDGGGHASHHAHMVADFRKRFWVSLIVTIPVLLLSPLIQSFFGYSIDFAGSMFFLFGLSSF
VYFYGGWPFLEGLFQELKKKQPGMMTLIALAISVAYFYSSAVVFGVEGKVFFWELVTLIDIMLLGHWIEMKSIMGASQAL
EELAKLMPSEAHRLKESGDIEEVKIEDLQSQDKVLIKPGEKIPVDGIVLEGESDVDESAITGESKPVSKKKDDKVIGGAV
NGEGSLTVQVTKTGKDSYLSQVIELVRIASESKSRAQGLADKAAFWLTIIAITAGAATLITWLVLGKEFVFALERMVTVM
VITCPHALGLAIPLVIAVITSISAKNGLLIRNRTSFEGARNIDVVVFDKTGTLTKGEFGVSDIVTFGGWKEDELLRDVAA
IETNSEHTIAKGIVKKAKEKKLDLPKVENFSSLPGKGAKARIQGKQIFVGNKGIFEIAEVSSTDDAQKQANEFASQGKTL
VFVASENKIQGIIALSDIIRDESKEAIKRLKKQDISVSMITGDNQATAKFVADQLGLDSFFAEVLPDKKSEKIKKLQSEG
RKVAMVGDGVNDAPALAQADVGIAIGAGTDVAVETADVVLIENDPRNVLDIIRLSAINHRKTVQNLAWATGYNVFAIPLA
AGVLYSYGIILAPAMGAIIMSLSTVIVAINSRLIKFQKEY

Sequences:

>Translated_680_residues
MKHRNRQTKHNMNAEHTNHTDGGGHASHHAHMVADFRKRFWVSLIVTIPVLLLSPLIQSFFGYSIDFAGSMFFLFGLSSF
VYFYGGWPFLEGLFQELKKKQPGMMTLIALAISVAYFYSSAVVFGVEGKVFFWELVTLIDIMLLGHWIEMKSIMGASQAL
EELAKLMPSEAHRLKESGDIEEVKIEDLQSQDKVLIKPGEKIPVDGIVLEGESDVDESAITGESKPVSKKKDDKVIGGAV
NGEGSLTVQVTKTGKDSYLSQVIELVRIASESKSRAQGLADKAAFWLTIIAITAGAATLITWLVLGKEFVFALERMVTVM
VITCPHALGLAIPLVIAVITSISAKNGLLIRNRTSFEGARNIDVVVFDKTGTLTKGEFGVSDIVTFGGWKEDELLRDVAA
IETNSEHTIAKGIVKKAKEKKLDLPKVENFSSLPGKGAKARIQGKQIFVGNKGIFEIAEVSSTDDAQKQANEFASQGKTL
VFVASENKIQGIIALSDIIRDESKEAIKRLKKQDISVSMITGDNQATAKFVADQLGLDSFFAEVLPDKKSEKIKKLQSEG
RKVAMVGDGVNDAPALAQADVGIAIGAGTDVAVETADVVLIENDPRNVLDIIRLSAINHRKTVQNLAWATGYNVFAIPLA
AGVLYSYGIILAPAMGAIIMSLSTVIVAINSRLIKFQKEY
>Mature_680_residues
MKHRNRQTKHNMNAEHTNHTDGGGHASHHAHMVADFRKRFWVSLIVTIPVLLLSPLIQSFFGYSIDFAGSMFFLFGLSSF
VYFYGGWPFLEGLFQELKKKQPGMMTLIALAISVAYFYSSAVVFGVEGKVFFWELVTLIDIMLLGHWIEMKSIMGASQAL
EELAKLMPSEAHRLKESGDIEEVKIEDLQSQDKVLIKPGEKIPVDGIVLEGESDVDESAITGESKPVSKKKDDKVIGGAV
NGEGSLTVQVTKTGKDSYLSQVIELVRIASESKSRAQGLADKAAFWLTIIAITAGAATLITWLVLGKEFVFALERMVTVM
VITCPHALGLAIPLVIAVITSISAKNGLLIRNRTSFEGARNIDVVVFDKTGTLTKGEFGVSDIVTFGGWKEDELLRDVAA
IETNSEHTIAKGIVKKAKEKKLDLPKVENFSSLPGKGAKARIQGKQIFVGNKGIFEIAEVSSTDDAQKQANEFASQGKTL
VFVASENKIQGIIALSDIIRDESKEAIKRLKKQDISVSMITGDNQATAKFVADQLGLDSFFAEVLPDKKSEKIKKLQSEG
RKVAMVGDGVNDAPALAQADVGIAIGAGTDVAVETADVVLIENDPRNVLDIIRLSAINHRKTVQNLAWATGYNVFAIPLA
AGVLYSYGIILAPAMGAIIMSLSTVIVAINSRLIKFQKEY

Specific function: Probably involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=733, Percent_Identity=34.5156889495225, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI115529486, Length=753, Percent_Identity=34.9269588313413, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI55743073, Length=589, Percent_Identity=35.4838709677419, Blast_Score=309, Evalue=7e-84,
Organism=Homo sapiens, GI48762687, Length=584, Percent_Identity=25.513698630137, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI48762689, Length=584, Percent_Identity=25.513698630137, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI48762691, Length=584, Percent_Identity=25.513698630137, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI48762685, Length=584, Percent_Identity=25.513698630137, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI118498343, Length=142, Percent_Identity=38.0281690140845, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI51944966, Length=255, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1786691, Length=655, Percent_Identity=36.030534351145, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1789879, Length=573, Percent_Identity=31.5881326352531, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI1786914, Length=469, Percent_Identity=31.3432835820896, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI2367363, Length=559, Percent_Identity=23.7924865831843, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17556548, Length=724, Percent_Identity=32.7348066298343, Blast_Score=295, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI71997262, Length=560, Percent_Identity=25, Blast_Score=122, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71997275, Length=560, Percent_Identity=25.3571428571429, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71997269, Length=560, Percent_Identity=25.3571428571429, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI193210130, Length=156, Percent_Identity=34.6153846153846, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554158, Length=156, Percent_Identity=34.6153846153846, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988506, Length=156, Percent_Identity=34.6153846153846, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17557770, Length=184, Percent_Identity=32.0652173913043, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI32566766, Length=184, Percent_Identity=32.0652173913043, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17557486, Length=184, Percent_Identity=32.0652173913043, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17559224, Length=230, Percent_Identity=25.6521739130435, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17531459, Length=122, Percent_Identity=34.4262295081967, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320475, Length=698, Percent_Identity=32.2349570200573, Blast_Score=316, Evalue=8e-87,
Organism=Saccharomyces cerevisiae, GI6319772, Length=676, Percent_Identity=29.8816568047337, Blast_Score=246, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6321430, Length=527, Percent_Identity=24.8576850094877, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6325221, Length=528, Percent_Identity=25, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6321271, Length=590, Percent_Identity=25.2542372881356, Blast_Score=123, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6321432, Length=172, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221329854, Length=473, Percent_Identity=31.9238900634249, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24668708, Length=169, Percent_Identity=33.7278106508876, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24668704, Length=169, Percent_Identity=33.7278106508876, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281366617, Length=169, Percent_Identity=33.7278106508876, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24668696, Length=169, Percent_Identity=33.7278106508876, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI161085803, Length=169, Percent_Identity=33.7278106508876, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281366676, Length=239, Percent_Identity=23.8493723849372, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.4 [H]

Molecular weight: Translated: 73946; Mature: 73946

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHRNRQTKHNMNAEHTNHTDGGGHASHHAHMVADFRKRFWVSLIVTIPVLLLSPLIQSF
CCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGYSIDFAGSMFFLFGLSSFVYFYGGWPFLEGLFQELKKKQPGMMTLIALAISVAYFYSS
HCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
AVVFGVEGKVFFWELVTLIDIMLLGHWIEMKSIMGASQALEELAKLMPSEAHRLKESGDI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
EEVKIEDLQSQDKVLIKPGEKIPVDGIVLEGESDVDESAITGESKPVSKKKDDKVIGGAV
CEEEHHHCCCCCCEEECCCCCCCCCCEEECCCCCCCHHHCCCCCCCCCCCCCCCEECEEE
NGEGSLTVQVTKTGKDSYLSQVIELVRIASESKSRAQGLADKAAFWLTIIAITAGAATLI
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHHHHCCHHHHH
TWLVLGKEFVFALERMVTVMVITCPHALGLAIPLVIAVITSISAKNGLLIRNRTSFEGAR
HHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
NIDVVVFDKTGTLTKGEFGVSDIVTFGGWKEDELLRDVAAIETNSEHTIAKGIVKKAKEK
CCEEEEECCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KLDLPKVENFSSLPGKGAKARIQGKQIFVGNKGIFEIAEVSSTDDAQKQANEFASQGKTL
CCCCCCCCCCCCCCCCCCCEEECCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCEE
VFVASENKIQGIIALSDIIRDESKEAIKRLKKQDISVSMITGDNQATAKFVADQLGLDSF
EEEECCCCCEEHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCHHHH
FAEVLPDKKSEKIKKLQSEGRKVAMVGDGVNDAPALAQADVGIAIGAGTDVAVETADVVL
HHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCCEEEECCCCEEEEEEEEEE
IENDPRNVLDIIRLSAINHRKTVQNLAWATGYNVFAIPLAAGVLYSYGIILAPAMGAIIM
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
SLSTVIVAINSRLIKFQKEY
HHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MKHRNRQTKHNMNAEHTNHTDGGGHASHHAHMVADFRKRFWVSLIVTIPVLLLSPLIQSF
CCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGYSIDFAGSMFFLFGLSSFVYFYGGWPFLEGLFQELKKKQPGMMTLIALAISVAYFYSS
HCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
AVVFGVEGKVFFWELVTLIDIMLLGHWIEMKSIMGASQALEELAKLMPSEAHRLKESGDI
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
EEVKIEDLQSQDKVLIKPGEKIPVDGIVLEGESDVDESAITGESKPVSKKKDDKVIGGAV
CEEEHHHCCCCCCEEECCCCCCCCCCEEECCCCCCCHHHCCCCCCCCCCCCCCCEECEEE
NGEGSLTVQVTKTGKDSYLSQVIELVRIASESKSRAQGLADKAAFWLTIIAITAGAATLI
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHHHHCCHHHHH
TWLVLGKEFVFALERMVTVMVITCPHALGLAIPLVIAVITSISAKNGLLIRNRTSFEGAR
HHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
NIDVVVFDKTGTLTKGEFGVSDIVTFGGWKEDELLRDVAAIETNSEHTIAKGIVKKAKEK
CCEEEEECCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KLDLPKVENFSSLPGKGAKARIQGKQIFVGNKGIFEIAEVSSTDDAQKQANEFASQGKTL
CCCCCCCCCCCCCCCCCCCEEECCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCEE
VFVASENKIQGIIALSDIIRDESKEAIKRLKKQDISVSMITGDNQATAKFVADQLGLDSF
EEEECCCCCEEHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCHHHH
FAEVLPDKKSEKIKKLQSEGRKVAMVGDGVNDAPALAQADVGIAIGAGTDVAVETADVVL
HHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCCEEEECCCCEEEEEEEEEE
IENDPRNVLDIIRLSAINHRKTVQNLAWATGYNVFAIPLAAGVLYSYGIILAPAMGAIIM
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
SLSTVIVAINSRLIKFQKEY
HHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]