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The map label for this gene is cdd [H]

Identifier: 160903259

GI number: 160903259

Start: 2013217

End: 2013615

Strand: Direct

Name: cdd [H]

Synonym: Pmob_1828

Alternate gene names: 160903259

Gene position: 2013217-2013615 (Clockwise)

Preceding gene: 160903258

Following gene: 160903260

Centisome position: 92.79

GC content: 38.35

Gene sequence:

>399_bases
ATGAATGATAAAACTATTGTTGAAAAATTGTATGAAGAAGCTATGAAAGCAAGAGAAAATGCATATGCCCCTTATTCTAA
TTTTAAGGTTGGAGCATGTTTGTTATCAGATGATGGAGAAATATTTTCAGGTTGTAACGTAGAAAATGCTTCTTATGGGT
TATCTATATGTGCCGAAAGGAACGCAATATTTTCTGCTGTTGCCAAGGGCAAACGTGAATTCAAAGCCATGTTAGTCGTT
GCAGAAGGAGAGGCACCTGTAAAACCATGTGGGGCATGTAGGCAAGTAATGGCTGAGTTCGGAGATTTCGACGTTTATCT
AGCAAATACGAAGGGGAAAATAGAAAAAACAAGGGTAAGTGAGTTACTACCAAATGCCTTTAGCCCCAAAGATCTGTGA

Upstream 100 bases:

>100_bases
GAAATTGTTTCCGTAACTATCAATAAGATAGATAAAGTTAAAATAACTGTACATCCAAAAATGCAAACAGAAAACCAAGA
AGGGACTGGTAAAGAGAAAG

Downstream 100 bases:

>100_bases
AAGATCTAAACATCCGTTTCATAAAGTAGGCTAGTAGGAGTTGAGACTAAGTCTTCTATTTTTCCTTATGCTTGGGAAGC
GGGCGCATCTTTCAAAAATA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MNDKTIVEKLYEEAMKARENAYAPYSNFKVGACLLSDDGEIFSGCNVENASYGLSICAERNAIFSAVAKGKREFKAMLVV
AEGEAPVKPCGACRQVMAEFGDFDVYLANTKGKIEKTRVSELLPNAFSPKDL

Sequences:

>Translated_132_residues
MNDKTIVEKLYEEAMKARENAYAPYSNFKVGACLLSDDGEIFSGCNVENASYGLSICAERNAIFSAVAKGKREFKAMLVV
AEGEAPVKPCGACRQVMAEFGDFDVYLANTKGKIEKTRVSELLPNAFSPKDL
>Mature_132_residues
MNDKTIVEKLYEEAMKARENAYAPYSNFKVGACLLSDDGEIFSGCNVENASYGLSICAERNAIFSAVAKGKREFKAMLVV
AEGEAPVKPCGACRQVMAEFGDFDVYLANTKGKIEKTRVSELLPNAFSPKDL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=128, Percent_Identity=47.65625, Blast_Score=125, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17551074, Length=126, Percent_Identity=57.1428571428571, Blast_Score=147, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17540514, Length=125, Percent_Identity=51.2, Blast_Score=127, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323274, Length=131, Percent_Identity=43.5114503816794, Blast_Score=104, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24582741, Length=129, Percent_Identity=45.7364341085271, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19920920, Length=101, Percent_Identity=48.5148514851485, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24582744, Length=137, Percent_Identity=35.7664233576642, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14417; Mature: 14417

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKTIVEKLYEEAMKARENAYAPYSNFKVGACLLSDDGEIFSGCNVENASYGLSICAER
CCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEECCCCCCCCCCCCHHHHHH
NAIFSAVAKGKREFKAMLVVAEGEAPVKPCGACRQVMAEFGDFDVYLANTKGKIEKTRVS
HHHHHHHHHHHHCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ELLPNAFSPKDL
HHCCCCCCCCCC
>Mature Secondary Structure
MNDKTIVEKLYEEAMKARENAYAPYSNFKVGACLLSDDGEIFSGCNVENASYGLSICAER
CCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEECCCCCCCCCCCCHHHHHH
NAIFSAVAKGKREFKAMLVVAEGEAPVKPCGACRQVMAEFGDFDVYLANTKGKIEKTRVS
HHHHHHHHHHHHCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ELLPNAFSPKDL
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]