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The map label for this gene is hrcA [H]

Identifier: 160903254

GI number: 160903254

Start: 2007920

End: 2008927

Strand: Direct

Name: hrcA [H]

Synonym: Pmob_1823

Alternate gene names: 160903254

Gene position: 2007920-2008927 (Clockwise)

Preceding gene: 160903244

Following gene: 160903255

Centisome position: 92.55

GC content: 31.35

Gene sequence:

>1008_bases
ATGGCTAAGGTGCTACACGATAGACAAAAAGAAATTCTAAAAACCATTGTTGAATTATACCTAAAAAACGATAAACCAGT
TAGCTCAGACGAAGTTTTGGAAAACTCAAATATAAAAGCCAGTAGCGCCACTATCAGAAACGATATGCAAAAACTTCAAA
AATTAGGATACATTTATCAACAACACTCAAGCGGTGGAAGAATTCCTACAGATTCCGCTTTGAAGATCTATTTTCAAATG
ATAAAAGACGCCTACAACCAAGAGGATACACATATTGATATTCCAAAAAAGTACAAATTTTATGATTTAAATCTTATGTT
TCAAAGCTTGAGTGAACTAATATCCAATACTTTGGAAGGTTTGGTGATTTTTGAATATCCTAATCCAAAGTATGTATATA
TAACAAGGGTGACTGTTACTCCCTTAATGGAGACAAATAACGTCATTACTATTTTAACAAATTTAGGCTTAGCTGTATCC
AGGACGGTTGAAATATATGGTTTGCCACCTTCAAAGGAATTGGAAAATATTTTGAATAACGGTCTTGTTGGCAAGTCTTT
TCATTCACTTTTCATGTTTCTTTCAGCTCCAAAATTTGAAACAGAAGATCTAAGGGTGACTAATTTTATTGAGATTTTAG
GGCATCTAACATCTGAGTTCAACAGAAAAAAATATATTATAAGTGGTTTGGAAAAAATCATCTCTCAATCTATCCCAGAC
TTGGAAGCTATAGAAGCGTTGGCTTCTATGGTTGAAAATGATACAATCAAAGAAGGAATATTTAAACTTTTAGATTTCAC
TGATGATATAGAAATATTGTTTGGCGAAGATTTAAACTCTAAAGCTCTAAAAAAAATGGTATTTTTCTACACTACTTACA
AATTAAATGCCGATCCCCTTGGTAGGGTGCTGTTTATAACTCAAAAATACTGTAATTATGAAAAAAATTACTATTTTTTG
AGAGAGTATATTTCGAGACTCTCAGAGATTATATCAAAAAATTTATGA

Upstream 100 bases:

>100_bases
CCTAAATGTTAGTTGTTACAATGTGGTAAATTAATATATTTGACAATGTATATAAGACCTGGTATCATATTATTAGCACT
TAATATGCGGGAGTGATAAA

Downstream 100 bases:

>100_bases
AATTAGTATATAATTTTGTTTATAGACTTAGTTTGTTGTAGTATACAAACGATGTTTTTAAATGATTTTGACTTTGAATT
CGGGGTTTTTAAGGGGCTTG

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAKVLHDRQKEILKTIVELYLKNDKPVSSDEVLENSNIKASSATIRNDMQKLQKLGYIYQQHSSGGRIPTDSALKIYFQM
IKDAYNQEDTHIDIPKKYKFYDLNLMFQSLSELISNTLEGLVIFEYPNPKYVYITRVTVTPLMETNNVITILTNLGLAVS
RTVEIYGLPPSKELENILNNGLVGKSFHSLFMFLSAPKFETEDLRVTNFIEILGHLTSEFNRKKYIISGLEKIISQSIPD
LEAIEALASMVENDTIKEGIFKLLDFTDDIEILFGEDLNSKALKKMVFFYTTYKLNADPLGRVLFITQKYCNYEKNYYFL
REYISRLSEIISKNL

Sequences:

>Translated_335_residues
MAKVLHDRQKEILKTIVELYLKNDKPVSSDEVLENSNIKASSATIRNDMQKLQKLGYIYQQHSSGGRIPTDSALKIYFQM
IKDAYNQEDTHIDIPKKYKFYDLNLMFQSLSELISNTLEGLVIFEYPNPKYVYITRVTVTPLMETNNVITILTNLGLAVS
RTVEIYGLPPSKELENILNNGLVGKSFHSLFMFLSAPKFETEDLRVTNFIEILGHLTSEFNRKKYIISGLEKIISQSIPD
LEAIEALASMVENDTIKEGIFKLLDFTDDIEILFGEDLNSKALKKMVFFYTTYKLNADPLGRVLFITQKYCNYEKNYYFL
REYISRLSEIISKNL
>Mature_334_residues
AKVLHDRQKEILKTIVELYLKNDKPVSSDEVLENSNIKASSATIRNDMQKLQKLGYIYQQHSSGGRIPTDSALKIYFQMI
KDAYNQEDTHIDIPKKYKFYDLNLMFQSLSELISNTLEGLVIFEYPNPKYVYITRVTVTPLMETNNVITILTNLGLAVSR
TVEIYGLPPSKELENILNNGLVGKSFHSLFMFLSAPKFETEDLRVTNFIEILGHLTSEFNRKKYIISGLEKIISQSIPDL
EAIEALASMVENDTIKEGIFKLLDFTDDIEILFGEDLNSKALKKMVFFYTTYKLNADPLGRVLFITQKYCNYEKNYYFLR
EYISRLSEIISKNL

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR023120
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38665; Mature: 38534

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLHDRQKEILKTIVELYLKNDKPVSSDEVLENSNIKASSATIRNDMQKLQKLGYIYQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
QHSSGGRIPTDSALKIYFQMIKDAYNQEDTHIDIPKKYKFYDLNLMFQSLSELISNTLEG
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHCC
LVIFEYPNPKYVYITRVTVTPLMETNNVITILTNLGLAVSRTVEIYGLPPSKELENILNN
EEEEECCCCCEEEEEEEEEEEEECCCCEEEEEECCCEEEECEEEEEECCCCHHHHHHHHC
GLVGKSFHSLFMFLSAPKFETEDLRVTNFIEILGHLTSEFNRKKYIISGLEKIISQSIPD
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCC
LEAIEALASMVENDTIKEGIFKLLDFTDDIEILFGEDLNSKALKKMVFFYTTYKLNADPL
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHEEEEECCCCC
GRVLFITQKYCNYEKNYYFLREYISRLSEIISKNL
CCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKVLHDRQKEILKTIVELYLKNDKPVSSDEVLENSNIKASSATIRNDMQKLQKLGYIYQ
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
QHSSGGRIPTDSALKIYFQMIKDAYNQEDTHIDIPKKYKFYDLNLMFQSLSELISNTLEG
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHCC
LVIFEYPNPKYVYITRVTVTPLMETNNVITILTNLGLAVSRTVEIYGLPPSKELENILNN
EEEEECCCCCEEEEEEEEEEEEECCCCEEEEEECCCEEEECEEEEEECCCCHHHHHHHHC
GLVGKSFHSLFMFLSAPKFETEDLRVTNFIEILGHLTSEFNRKKYIISGLEKIISQSIPD
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCC
LEAIEALASMVENDTIKEGIFKLLDFTDDIEILFGEDLNSKALKKMVFFYTTYKLNADPL
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHEEEEECCCCC
GRVLFITQKYCNYEKNYYFLREYISRLSEIISKNL
CCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA