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The map label for this gene is atzB [H]

Identifier: 160903171

GI number: 160903171

Start: 1901524

End: 1902891

Strand: Direct

Name: atzB [H]

Synonym: Pmob_1736

Alternate gene names: 160903171

Gene position: 1901524-1902891 (Clockwise)

Preceding gene: 160903170

Following gene: 160903172

Centisome position: 87.65

GC content: 34.94

Gene sequence:

>1368_bases
ATGTCAAGCATATTGATTAAAAAAGCTAAAGTTATAACCACTATGAACGCTAATAAGGATCAATTGAAGGATCACGATAT
TTTAATTAAAGATAAGATAATACATAAGATTTCTCCAAATATAGATGTATCAAATGAACAAATAGATGAAGTTATAGATG
GTTCCAAATATTATGTTTATCCAGGATTAATTAACACACATCATCATTTCTATCAAACCTTTACAAGAAACATTCCTCAA
GTACAAAATGTAGAATTATTTGATTGGTTAAAGTTTTTGTATCCCATTTGGTCAAAGTTGACACCAGAGGTTGTTTACTA
CAGTACTTTAGTTGCAACAGCCGAATTACTCAAAACTGGATGCACAACATCTGTTGATCACTTCTATGTTTTTCCAAAAA
ATCAACCACCAGATCTTCTTGACAACGAATTTTATGCTGCAAAAGAAATTGGGATCAGATTACATGGAAGTAGAGGAAGT
ATGTCATTGAGTGAAAAAGATGGAGGACTTCCTCCTGATTCAGTAGTTCAAACAGAAAAAGAAATATTGAAAGATTCCCA
AAGAGTTATTGAAAAATTTCACGATCCTTCTCCATTTGCCATGCATAGAGTCATTCTAGCTCCTTGTTCTCCATTTTCTG
TAACCTCTACACTTCTCAACGAATCTATTAAATTGGCAAGAGAATATAGTGTTTGTAGTCATACACATCTAGCTGAAACA
AAAGATGAAGAGAGATTTTGTATTGATACTTTTGGGAAAAGGCCATTAGAATACATGGAGAGTTTAGATTGGTTAGGTTC
TGATGTATGGTTTGCCCATGGGGTTCATTTCAACGAAGAAGAGATAGATAAGTTGGCATTAACTAAAACAGGGGTTGCTC
ATTGCCCTGTTTCGAATTCAAAACTCGCCTCTGGGGCTGCAAAGATCCCCTCTATGTTAAAAAAGGGTGTCAAAGTTAGC
CTGGCTGTCGATGGGAGTGCAAGCAACGATTCTTCTAATATGATTTTAGAAATGAAAACTGCTTTTTTGATGAGCAGATT
AATTTACGGTATCAACGCTATCACATCCGAAGATGTGCTGAATATAGCCACAAAAGGTGGAAGTGAAGTTATAAATCAGC
CGGAAATTGGAAGTTTAGAAGAAGGTAAGGCCGCAGATATGTTCTTGGTTCGTTGGGATCGATTGGGTTATACAGGAGGC
TTTTATGATCCTATTTCAATGATTATTAATACAGGTGATTCTCAAATTGTAGATATTACGATAGTCAATGGAGAAATAGT
TGTAAAAGATGGTGAACTTGTTAAAGTTGATGAAAGAAAAATCATCGAAAAGGCTAATGAACTATCTAAAAGGATGCTCG
AGGCCTAA

Upstream 100 bases:

>100_bases
TAAAAACTGCAATAGAAGGAAATCTCTGTAGATGTACTGGATATCAGCAAATAGTCGAAGCAATAGAAGCAGTCACACAA
ATGAAGGAAGGCTGATATAT

Downstream 100 bases:

>100_bases
AAATTTGGAGGTAAATGAAGATGTTGTTAATAGGTAACGCCACTGTTCTCACCTTTGACGAAGAAACTCCTATAATTAAT
AATGGTGCGGTGTTAATAGA

Product: amidohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSSILIKKAKVITTMNANKDQLKDHDILIKDKIIHKISPNIDVSNEQIDEVIDGSKYYVYPGLINTHHHFYQTFTRNIPQ
VQNVELFDWLKFLYPIWSKLTPEVVYYSTLVATAELLKTGCTTSVDHFYVFPKNQPPDLLDNEFYAAKEIGIRLHGSRGS
MSLSEKDGGLPPDSVVQTEKEILKDSQRVIEKFHDPSPFAMHRVILAPCSPFSVTSTLLNESIKLAREYSVCSHTHLAET
KDEERFCIDTFGKRPLEYMESLDWLGSDVWFAHGVHFNEEEIDKLALTKTGVAHCPVSNSKLASGAAKIPSMLKKGVKVS
LAVDGSASNDSSNMILEMKTAFLMSRLIYGINAITSEDVLNIATKGGSEVINQPEIGSLEEGKAADMFLVRWDRLGYTGG
FYDPISMIINTGDSQIVDITIVNGEIVVKDGELVKVDERKIIEKANELSKRMLEA

Sequences:

>Translated_455_residues
MSSILIKKAKVITTMNANKDQLKDHDILIKDKIIHKISPNIDVSNEQIDEVIDGSKYYVYPGLINTHHHFYQTFTRNIPQ
VQNVELFDWLKFLYPIWSKLTPEVVYYSTLVATAELLKTGCTTSVDHFYVFPKNQPPDLLDNEFYAAKEIGIRLHGSRGS
MSLSEKDGGLPPDSVVQTEKEILKDSQRVIEKFHDPSPFAMHRVILAPCSPFSVTSTLLNESIKLAREYSVCSHTHLAET
KDEERFCIDTFGKRPLEYMESLDWLGSDVWFAHGVHFNEEEIDKLALTKTGVAHCPVSNSKLASGAAKIPSMLKKGVKVS
LAVDGSASNDSSNMILEMKTAFLMSRLIYGINAITSEDVLNIATKGGSEVINQPEIGSLEEGKAADMFLVRWDRLGYTGG
FYDPISMIINTGDSQIVDITIVNGEIVVKDGELVKVDERKIIEKANELSKRMLEA
>Mature_454_residues
SSILIKKAKVITTMNANKDQLKDHDILIKDKIIHKISPNIDVSNEQIDEVIDGSKYYVYPGLINTHHHFYQTFTRNIPQV
QNVELFDWLKFLYPIWSKLTPEVVYYSTLVATAELLKTGCTTSVDHFYVFPKNQPPDLLDNEFYAAKEIGIRLHGSRGSM
SLSEKDGGLPPDSVVQTEKEILKDSQRVIEKFHDPSPFAMHRVILAPCSPFSVTSTLLNESIKLAREYSVCSHTHLAETK
DEERFCIDTFGKRPLEYMESLDWLGSDVWFAHGVHFNEEEIDKLALTKTGVAHCPVSNSKLASGAAKIPSMLKKGVKVSL
AVDGSASNDSSNMILEMKTAFLMSRLIYGINAITSEDVLNIATKGGSEVINQPEIGSLEEGKAADMFLVRWDRLGYTGGF
YDPISMIINTGDSQIVDITIVNGEIVVKDGELVKVDERKIIEKANELSKRMLEA

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=394, Percent_Identity=25.3807106598985, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789249, Length=389, Percent_Identity=26.2210796915167, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87082177, Length=403, Percent_Identity=23.3250620347395, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540282, Length=425, Percent_Identity=22.5882352941176, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319963, Length=344, Percent_Identity=24.7093023255814, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24643849, Length=357, Percent_Identity=23.249299719888, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 50908; Mature: 50777

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSILIKKAKVITTMNANKDQLKDHDILIKDKIIHKISPNIDVSNEQIDEVIDGSKYYVY
CCCCCEEHEEEEEEECCCHHHHCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEE
PGLINTHHHFYQTFTRNIPQVQNVELFDWLKFLYPIWSKLTPEVVYYSTLVATAELLKTG
CCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
CTTSVDHFYVFPKNQPPDLLDNEFYAAKEIGIRLHGSRGSMSLSEKDGGLPPDSVVQTEK
CCCCCCEEEEECCCCCCCCCCCCCCEEEEECEEEECCCCCCEECCCCCCCCCHHHHHHHH
EILKDSQRVIEKFHDPSPFAMHRVILAPCSPFSVTSTLLNESIKLAREYSVCSHTHLAET
HHHHHHHHHHHHHCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
KDEERFCIDTFGKRPLEYMESLDWLGSDVWFAHGVHFNEEEIDKLALTKTGVAHCPVSNS
CCCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEECCCCCC
KLASGAAKIPSMLKKGVKVSLAVDGSASNDSSNMILEMKTAFLMSRLIYGINAITSEDVL
HHHCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHH
NIATKGGSEVINQPEIGSLEEGKAADMFLVRWDRLGYTGGFYDPISMIINTGDSQIVDIT
HHHCCCCHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHEECCCCEEEEEE
IVNGEIVVKDGELVKVDERKIIEKANELSKRMLEA
EECCEEEEECCCEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSILIKKAKVITTMNANKDQLKDHDILIKDKIIHKISPNIDVSNEQIDEVIDGSKYYVY
CCCCEEHEEEEEEECCCHHHHCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEE
PGLINTHHHFYQTFTRNIPQVQNVELFDWLKFLYPIWSKLTPEVVYYSTLVATAELLKTG
CCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
CTTSVDHFYVFPKNQPPDLLDNEFYAAKEIGIRLHGSRGSMSLSEKDGGLPPDSVVQTEK
CCCCCCEEEEECCCCCCCCCCCCCCEEEEECEEEECCCCCCEECCCCCCCCCHHHHHHHH
EILKDSQRVIEKFHDPSPFAMHRVILAPCSPFSVTSTLLNESIKLAREYSVCSHTHLAET
HHHHHHHHHHHHHCCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
KDEERFCIDTFGKRPLEYMESLDWLGSDVWFAHGVHFNEEEIDKLALTKTGVAHCPVSNS
CCCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEECCCCCC
KLASGAAKIPSMLKKGVKVSLAVDGSASNDSSNMILEMKTAFLMSRLIYGINAITSEDVL
HHHCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHH
NIATKGGSEVINQPEIGSLEEGKAADMFLVRWDRLGYTGGFYDPISMIINTGDSQIVDIT
HHHCCCCHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHEECCCCEEEEEE
IVNGEIVVKDGELVKVDERKIIEKANELSKRMLEA
EECCEEEEECCCEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]