Click here to switch to the map view.

The map label for this gene is dppA [H]

Identifier: 160903013

GI number: 160903013

Start: 1715536

End: 1717389

Strand: Direct

Name: dppA [H]

Synonym: Pmob_1575

Alternate gene names: 160903013

Gene position: 1715536-1717389 (Clockwise)

Preceding gene: 160903012

Following gene: 160903014

Centisome position: 79.07

GC content: 39.21

Gene sequence:

>1854_bases
ATGAAAAAAGTTTTTATTGTTCTTATGGTTACTTTGATGGGTGTTTTCGCTTTCTCACAGGTTAAAAACCCTGATATGAT
CTTCGATGCAACACTAAGTGAGCCAGATACTTTAGACCCTCACCATGCTTATGACACTTCTAGTGGTGAAGTTATTTTCA
ACGTATATGACAACTTGATAGCATACGATGGAGAAAGTTTGTCCAAGTTTGTTCCTATGCTCGCGACAGTTGTCCCTACA
GTTGAAAATGGTTATTTGAGAGATGGTGGAACAACATATGTCTTCCCAATAAGAGAAGGTGTTAAATTCCAGAACGGTAA
CGATTTAACCCCTGAAGATGTCGAATACACCTTCGAAAGAGCGCTGTTATACAACCCTGCTGGAGGACCAGTATGGATGT
ACTTAGACCCTATGTTTGGTGTTTTCAGCATTAGAACACTAGTAGAAGACTATGTAGGTGCTTCATGGGATACCATATTT
GATGATGATATGAATCCAACAACTCCAGAATACGAAGAAGCTTTAGTTAATTTCTATTATGATGTAATAGATCCTGCAGT
AGAAGTTCAAGGTAACGAAGTTCATGTTCATTTGGCAAGACCTTTTGCCCCATTTTTGAATGTACTTGCTTCAGGAAGTG
GTTGGGGTGCGATATTAGACAAAGAATACTCTATAGAAATAGGTGTATGGGATGGAAATGCAGAAGGTTGGTGGAAGTAT
CACGGATGGACGAAAGAACAGTCTCCTTATTTTGATCATGCTATGGGAACTGGTCCGTATAAGTTAGTAGAATGGGATCA
CGCTCAACAAAGGATAACGCTCGAAAGATTCGACGATTACTGGAGAGGTCCCGCACCAATAAGAAGAGTAATTATTCAAG
GTATAGACGAATGGTCAACAAGAAGAGCTATGCTTGAAACAGGCGATGCAGACATAGCTTATGTTCCTGCTCAGTATTTA
GATGTTGTGCTTTCTATGGATGGTCTGACCGTTATTCCTGGTACGCCTGAGGTTTCAATTACTTCTTTAGGCTTCAATTG
GCAAGTTGATCCTGAGTCCCCATACATTGGCTCTGGTCAATTGGATGGAAACGGTATTCCACCAGATTTCTTTGAAGATC
ATAATGTTAGATTAGGTTTCGCGTATGCCTTTGATTATGATGGTATGATAAATGAAGTCTTGAACGGTTTGGGTGAAAAA
GTTCCTACCGCTTTGCCAACCGGATTCTTAGGGTATAGTGAAGATCTCCCGACATACGAATTGGATCTGCAAAAGGCTGA
AAATTACTTTAAACGTGCTTACAAAGGTAGATTATGGCAAACAGGTTTCAAAATGACTATTCTTTACAATACAGGGAACG
ATTCAAGGAGAGTATCTGCTGAAATATTGAGAGATAATTTAGCAAAGATAAATCCTAGATTCCAAGTTGAAGTTAGAGGA
GTTCAATGGCCAACTTACTTAGATGAAAGAGAAAATATGATGCTTCCTGTTTACATCATTGGTTGGGTTGCTGATTTTCC
TGATCCACATAACTTTATTTTCACCTATTACCACAGTGAAGGTGATTACGGAGGGTACTACGGCGATAACTTTGCGGAAT
TTGCAAGCTTGCCAAGACCAGAATTTGGTGGAAAATCATTGAACAAAATGATAGAAGACGCAGCCCTTGAATCTGATCCT
GCTGTAAGAGAGCAAATGTATATAGATATTCAAGAATTTGTCTTTGATTATGCTCTTGTTTTGCCTCTTTATCAGCCACA
AGGGTTGAGAGTCCATCGTTCTTGGCTAAAAGGATGGATAAATAATCCAATTTGGCCCGGCGATTATTACTATAACTACA
CTAAAGTAGAGTAA

Upstream 100 bases:

>100_bases
GTTTATTAAATTGAAATGTGATAAAATATATTAGAAGATTATTCAGGAAAGTATTGTTGGTATGTACAAACGCTAATAAA
TCTGCAAAGGAGGTAGAGGT

Downstream 100 bases:

>100_bases
TAATTCTGCTAAGATAATGTAAAAAGAAAGTTTTTTGTAGTAAAATTTGAAGAGAGGGGTTTTCCCCTCTCTTTTTAAGT
GATTACTTATTAAGTATAAT

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MKKVFIVLMVTLMGVFAFSQVKNPDMIFDATLSEPDTLDPHHAYDTSSGEVIFNVYDNLIAYDGESLSKFVPMLATVVPT
VENGYLRDGGTTYVFPIREGVKFQNGNDLTPEDVEYTFERALLYNPAGGPVWMYLDPMFGVFSIRTLVEDYVGASWDTIF
DDDMNPTTPEYEEALVNFYYDVIDPAVEVQGNEVHVHLARPFAPFLNVLASGSGWGAILDKEYSIEIGVWDGNAEGWWKY
HGWTKEQSPYFDHAMGTGPYKLVEWDHAQQRITLERFDDYWRGPAPIRRVIIQGIDEWSTRRAMLETGDADIAYVPAQYL
DVVLSMDGLTVIPGTPEVSITSLGFNWQVDPESPYIGSGQLDGNGIPPDFFEDHNVRLGFAYAFDYDGMINEVLNGLGEK
VPTALPTGFLGYSEDLPTYELDLQKAENYFKRAYKGRLWQTGFKMTILYNTGNDSRRVSAEILRDNLAKINPRFQVEVRG
VQWPTYLDERENMMLPVYIIGWVADFPDPHNFIFTYYHSEGDYGGYYGDNFAEFASLPRPEFGGKSLNKMIEDAALESDP
AVREQMYIDIQEFVFDYALVLPLYQPQGLRVHRSWLKGWINNPIWPGDYYYNYTKVE

Sequences:

>Translated_617_residues
MKKVFIVLMVTLMGVFAFSQVKNPDMIFDATLSEPDTLDPHHAYDTSSGEVIFNVYDNLIAYDGESLSKFVPMLATVVPT
VENGYLRDGGTTYVFPIREGVKFQNGNDLTPEDVEYTFERALLYNPAGGPVWMYLDPMFGVFSIRTLVEDYVGASWDTIF
DDDMNPTTPEYEEALVNFYYDVIDPAVEVQGNEVHVHLARPFAPFLNVLASGSGWGAILDKEYSIEIGVWDGNAEGWWKY
HGWTKEQSPYFDHAMGTGPYKLVEWDHAQQRITLERFDDYWRGPAPIRRVIIQGIDEWSTRRAMLETGDADIAYVPAQYL
DVVLSMDGLTVIPGTPEVSITSLGFNWQVDPESPYIGSGQLDGNGIPPDFFEDHNVRLGFAYAFDYDGMINEVLNGLGEK
VPTALPTGFLGYSEDLPTYELDLQKAENYFKRAYKGRLWQTGFKMTILYNTGNDSRRVSAEILRDNLAKINPRFQVEVRG
VQWPTYLDERENMMLPVYIIGWVADFPDPHNFIFTYYHSEGDYGGYYGDNFAEFASLPRPEFGGKSLNKMIEDAALESDP
AVREQMYIDIQEFVFDYALVLPLYQPQGLRVHRSWLKGWINNPIWPGDYYYNYTKVE
>Mature_617_residues
MKKVFIVLMVTLMGVFAFSQVKNPDMIFDATLSEPDTLDPHHAYDTSSGEVIFNVYDNLIAYDGESLSKFVPMLATVVPT
VENGYLRDGGTTYVFPIREGVKFQNGNDLTPEDVEYTFERALLYNPAGGPVWMYLDPMFGVFSIRTLVEDYVGASWDTIF
DDDMNPTTPEYEEALVNFYYDVIDPAVEVQGNEVHVHLARPFAPFLNVLASGSGWGAILDKEYSIEIGVWDGNAEGWWKY
HGWTKEQSPYFDHAMGTGPYKLVEWDHAQQRITLERFDDYWRGPAPIRRVIIQGIDEWSTRRAMLETGDADIAYVPAQYL
DVVLSMDGLTVIPGTPEVSITSLGFNWQVDPESPYIGSGQLDGNGIPPDFFEDHNVRLGFAYAFDYDGMINEVLNGLGEK
VPTALPTGFLGYSEDLPTYELDLQKAENYFKRAYKGRLWQTGFKMTILYNTGNDSRRVSAEILRDNLAKINPRFQVEVRG
VQWPTYLDERENMMLPVYIIGWVADFPDPHNFIFTYYHSEGDYGGYYGDNFAEFASLPRPEFGGKSLNKMIEDAALESDP
AVREQMYIDIQEFVFDYALVLPLYQPQGLRVHRSWLKGWINNPIWPGDYYYNYTKVE

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=628, Percent_Identity=21.3375796178344, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1787762, Length=604, Percent_Identity=23.0132450331126, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081878, Length=587, Percent_Identity=21.1243611584327, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787551, Length=591, Percent_Identity=22.165820642978, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 70465; Mature: 70465

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVFIVLMVTLMGVFAFSQVKNPDMIFDATLSEPDTLDPHHAYDTSSGEVIFNVYDNLI
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHH
AYDGESLSKFVPMLATVVPTVENGYLRDGGTTYVFPIREGVKFQNGNDLTPEDVEYTFER
CCCCCHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEECCCCCCCCHHHHHHEEE
ALLYNPAGGPVWMYLDPMFGVFSIRTLVEDYVGASWDTIFDDDMNPTTPEYEEALVNFYY
EEEECCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHH
DVIDPAVEVQGNEVHVHLARPFAPFLNVLASGSGWGAILDKEYSIEIGVWDGNAEGWWKY
HHCCCCEEECCCEEEEEECCCHHHHHHHHHCCCCCEEEECCCEEEEEEEEECCCCCEEEE
HGWTKEQSPYFDHAMGTGPYKLVEWDHAQQRITLERFDDYWRGPAPIRRVIIQGIDEWST
CCCCCCCCCCHHHHCCCCCEEEEECCCHHHHEEHHHHHHHCCCCHHHHHHHHHCCCHHHH
RRAMLETGDADIAYVPAQYLDVVLSMDGLTVIPGTPEVSITSLGFNWQVDPESPYIGSGQ
HHHHHHCCCCCEEEECHHHHHHHHCCCCEEEECCCCCEEEEEECEEEEECCCCCCCCCCC
LDGNGIPPDFFEDHNVRLGFAYAFDYDGMINEVLNGLGEKVPTALPTGFLGYSEDLPTYE
CCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
LDLQKAENYFKRAYKGRLWQTGFKMTILYNTGNDSRRVSAEILRDNLAKINPRFQVEVRG
EHHHHHHHHHHHHHCCCEEECCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEEC
VQWPTYLDERENMMLPVYIIGWVADFPDPHNFIFTYYHSEGDYGGYYGDNFAEFASLPRP
EECCCCCCCCCCEEEEEEEEEEHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCC
EFGGKSLNKMIEDAALESDPAVREQMYIDIQEFVFDYALVLPLYQPQGLRVHRSWLKGWI
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
NNPIWPGDYYYNYTKVE
CCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKKVFIVLMVTLMGVFAFSQVKNPDMIFDATLSEPDTLDPHHAYDTSSGEVIFNVYDNLI
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHH
AYDGESLSKFVPMLATVVPTVENGYLRDGGTTYVFPIREGVKFQNGNDLTPEDVEYTFER
CCCCCHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEECCCCCCCCHHHHHHEEE
ALLYNPAGGPVWMYLDPMFGVFSIRTLVEDYVGASWDTIFDDDMNPTTPEYEEALVNFYY
EEEECCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHH
DVIDPAVEVQGNEVHVHLARPFAPFLNVLASGSGWGAILDKEYSIEIGVWDGNAEGWWKY
HHCCCCEEECCCEEEEEECCCHHHHHHHHHCCCCCEEEECCCEEEEEEEEECCCCCEEEE
HGWTKEQSPYFDHAMGTGPYKLVEWDHAQQRITLERFDDYWRGPAPIRRVIIQGIDEWST
CCCCCCCCCCHHHHCCCCCEEEEECCCHHHHEEHHHHHHHCCCCHHHHHHHHHCCCHHHH
RRAMLETGDADIAYVPAQYLDVVLSMDGLTVIPGTPEVSITSLGFNWQVDPESPYIGSGQ
HHHHHHCCCCCEEEECHHHHHHHHCCCCEEEECCCCCEEEEEECEEEEECCCCCCCCCCC
LDGNGIPPDFFEDHNVRLGFAYAFDYDGMINEVLNGLGEKVPTALPTGFLGYSEDLPTYE
CCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
LDLQKAENYFKRAYKGRLWQTGFKMTILYNTGNDSRRVSAEILRDNLAKINPRFQVEVRG
EHHHHHHHHHHHHHCCCEEECCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEEC
VQWPTYLDERENMMLPVYIIGWVADFPDPHNFIFTYYHSEGDYGGYYGDNFAEFASLPRP
EECCCCCCCCCCEEEEEEEEEEHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCC
EFGGKSLNKMIEDAALESDPAVREQMYIDIQEFVFDYALVLPLYQPQGLRVHRSWLKGWI
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
NNPIWPGDYYYNYTKVE
CCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]