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The map label for this gene is appB [H]

Identifier: 160903014

GI number: 160903014

Start: 1717513

End: 1718550

Strand: Direct

Name: appB [H]

Synonym: Pmob_1576

Alternate gene names: 160903014

Gene position: 1717513-1718550 (Clockwise)

Preceding gene: 160903013

Following gene: 160903015

Centisome position: 79.16

GC content: 35.84

Gene sequence:

>1038_bases
TTGACAACATACATCATCAGAAGGTTGTTATTACTACCTTTGATTATGTTAGGTGTTACTTTGATAGTTTTTTCTATGCA
ACAATTACTAGGACCTTTGAAACTTTTATCTACCTATGTTGATCCAAATACTTATGCAAAATTATCCGATCAAGATAAAA
TCGTTTTAATGGAGCAGTACGGTTTAACAGATCCTTGGCCAGTTAGATACGGCAAATGGATAGGGAATTTGTTCAAGGGT
GATCTTGGTTGGTCTGTAGTGGGGAAAGAACCTGTTTTAGATGCTTTATTACACAGGTTCCCCTATACGGTAGAATTAGC
ACTATACGCTATTTTTCCTATAATAGGGATTGGTATATGGTTGGGGGTTACCGCTGCAGTTCATCATAACTCATTTATAG
ATCAGGCTATTAGAATATTTGCTTTAATAGGTTGGTCTTTGCCAGATTTTGTTTGGGCAATACTGGTCTTATTGATATTT
TATATAGGTTTGGGATGGTTTCCACCAGGTAATCTGAGCTTATGGGCAGACGAAGTTGTAAAAAGTGCTACCTTTAATAA
TTATACTAATCTTTTGACTATAGATGCATTACTCAACGGAAGAATCGATATATTTTGGGATGCTTTAAGGCATATTTTAG
GACCCATTATTGCCATTTCTTGGTTATGGTGGGCTAATCTATTGAGAATTACCCGATCTTCGATGTTGGAAGTTCTTAGA
AGAGATTATATAAGAACTGCAAGATCAAAAGGTTTACCAGAAAGAGTAGTCATAAACAAACATGCCCGAAGAAATGCTCT
AATTCCAGTTGTAACAACCGCAGGTCAAATGGTTATTGGTTTATTGGCAGGCGTTGTTATAGTAGAGATGGTTTTTGTTA
GAACAGGTTTGGGATCATTTGCGGCAACAGCGGCTCAGACTCTAGATTATGCTTCTATAATGGGTGTTTTATTATTTACT
TCTTTCATACTTATTGTTGGAAATCTTATAATCGATATATCGTATGCATTTATTGATCCAAGAATCAGGTTAGGGTGA

Upstream 100 bases:

>100_bases
AAGAAAGTTTTTTGTAGTAAAATTTGAAGAGAGGGGTTTTCCCCTCTCTTTTTAAGTGATTACTTATTAAGTATAATTCA
CAGAGCGGAGGTGTCTACTT

Downstream 100 bases:

>100_bases
GGTGAAAATTGTGAATGAAGAAACAAAAAGGGCTTTAAAGCGTTTTTTTACTAATCCTTCCGCCATTATTGGCTTTTCTA
TATTAGTTTTTTTCATAATT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTTYIIRRLLLLPLIMLGVTLIVFSMQQLLGPLKLLSTYVDPNTYAKLSDQDKIVLMEQYGLTDPWPVRYGKWIGNLFKG
DLGWSVVGKEPVLDALLHRFPYTVELALYAIFPIIGIGIWLGVTAAVHHNSFIDQAIRIFALIGWSLPDFVWAILVLLIF
YIGLGWFPPGNLSLWADEVVKSATFNNYTNLLTIDALLNGRIDIFWDALRHILGPIIAISWLWWANLLRITRSSMLEVLR
RDYIRTARSKGLPERVVINKHARRNALIPVVTTAGQMVIGLLAGVVIVEMVFVRTGLGSFAATAAQTLDYASIMGVLLFT
SFILIVGNLIIDISYAFIDPRIRLG

Sequences:

>Translated_345_residues
MTTYIIRRLLLLPLIMLGVTLIVFSMQQLLGPLKLLSTYVDPNTYAKLSDQDKIVLMEQYGLTDPWPVRYGKWIGNLFKG
DLGWSVVGKEPVLDALLHRFPYTVELALYAIFPIIGIGIWLGVTAAVHHNSFIDQAIRIFALIGWSLPDFVWAILVLLIF
YIGLGWFPPGNLSLWADEVVKSATFNNYTNLLTIDALLNGRIDIFWDALRHILGPIIAISWLWWANLLRITRSSMLEVLR
RDYIRTARSKGLPERVVINKHARRNALIPVVTTAGQMVIGLLAGVVIVEMVFVRTGLGSFAATAAQTLDYASIMGVLLFT
SFILIVGNLIIDISYAFIDPRIRLG
>Mature_344_residues
TTYIIRRLLLLPLIMLGVTLIVFSMQQLLGPLKLLSTYVDPNTYAKLSDQDKIVLMEQYGLTDPWPVRYGKWIGNLFKGD
LGWSVVGKEPVLDALLHRFPYTVELALYAIFPIIGIGIWLGVTAAVHHNSFIDQAIRIFALIGWSLPDFVWAILVLLIFY
IGLGWFPPGNLSLWADEVVKSATFNNYTNLLTIDALLNGRIDIFWDALRHILGPIIAISWLWWANLLRITRSSMLEVLRR
DYIRTARSKGLPERVVINKHARRNALIPVVTTAGQMVIGLLAGVVIVEMVFVRTGLGSFAATAAQTLDYASIMGVLLFTS
FILIVGNLIIDISYAFIDPRIRLG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=347, Percent_Identity=34.5821325648415, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787761, Length=342, Percent_Identity=36.2573099415205, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787497, Length=345, Percent_Identity=30.7246376811594, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787053, Length=345, Percent_Identity=31.8840579710145, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789888, Length=349, Percent_Identity=30.3724928366762, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=31.8681318681319, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1788504, Length=304, Percent_Identity=29.2763157894737, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38723; Mature: 38591

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYIIRRLLLLPLIMLGVTLIVFSMQQLLGPLKLLSTYVDPNTYAKLSDQDKIVLMEQY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCC
GLTDPWPVRYGKWIGNLFKGDLGWSVVGKEPVLDALLHRFPYTVELALYAIFPIIGIGIW
CCCCCCCHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LGVTAAVHHNSFIDQAIRIFALIGWSLPDFVWAILVLLIFYIGLGWFPPGNLSLWADEVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
KSATFNNYTNLLTIDALLNGRIDIFWDALRHILGPIIAISWLWWANLLRITRSSMLEVLR
HHHHCCCCHHHEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDYIRTARSKGLPERVVINKHARRNALIPVVTTAGQMVIGLLAGVVIVEMVFVRTGLGSF
HHHHHHHHHCCCCHHHHHCCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AATAAQTLDYASIMGVLLFTSFILIVGNLIIDISYAFIDPRIRLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTYIIRRLLLLPLIMLGVTLIVFSMQQLLGPLKLLSTYVDPNTYAKLSDQDKIVLMEQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCC
GLTDPWPVRYGKWIGNLFKGDLGWSVVGKEPVLDALLHRFPYTVELALYAIFPIIGIGIW
CCCCCCCHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LGVTAAVHHNSFIDQAIRIFALIGWSLPDFVWAILVLLIFYIGLGWFPPGNLSLWADEVV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
KSATFNNYTNLLTIDALLNGRIDIFWDALRHILGPIIAISWLWWANLLRITRSSMLEVLR
HHHHCCCCHHHEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDYIRTARSKGLPERVVINKHARRNALIPVVTTAGQMVIGLLAGVVIVEMVFVRTGLGSF
HHHHHHHHHCCCCHHHHHCCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AATAAQTLDYASIMGVLLFTSFILIVGNLIIDISYAFIDPRIRLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]