Click here to switch to the map view.

The map label for this gene is gpsA

Identifier: 160902832

GI number: 160902832

Start: 1492956

End: 1493960

Strand: Direct

Name: gpsA

Synonym: Pmob_1386

Alternate gene names: 160902832

Gene position: 1492956-1493960 (Clockwise)

Preceding gene: 160902831

Following gene: 160902833

Centisome position: 68.81

GC content: 35.22

Gene sequence:

>1005_bases
ATGCCTCATATAACGGTTTTGGGTGCGGGTAGTTGGGGAACCGCTATATCGAAGCATTTAGTCGATAATGATCAAAAAGT
AACAATTTGGGATAGGAACAAAAAACTCCTACAAGAAATAAAAGAAGGACGCAATTCCCGATATTTGCCTACCCTAAAAC
TTCCATCAAATGATATTAATGTTGAAGGGGATATAAATGAAAGCTTAACTAATGCACAAATTGTTATTTTAGCCGTCCCT
GTTCAACATATATCAGAGGTATTAAGCAAAATTCACAAGAGCTCTCTTACAAATAAAGAGGTTATTTTTGTCAATCTATC
AAAAGGTATAGAAATTAACAACCGAAAAATACCAAGTAAAATTTTTGAGGAATACCTATCAGGATTTAATTATTGTACTC
TTAGCGGTCCAAGTCATGCGGAAGAAGTAGCAGAAAATGTACCTACATCAGTTGTAATTGGTGGTATAGATGATCAGGTC
AACAAATATATACAGGAAATTTTTAGCAGTGAAACTTTTAGGGTGTATACTAACAATGATTTGATAGGAGTAGAAATCAG
TGGTGCTATAAAAAATATATATGCAATAGGTGCGGGTATAATAGATGGATTTGGGAAATGGGATAACACAAAAGCTGCCC
TAATTACCCGATCTTTGGTTGAAATTATTAGGTATGGAACGTATTATGGAGGAAAGAAAGAAACGTTCATGGGGTTAGCG
GGAATTGGAGATCTTGTTGTAACATGCACTAGCTCACATAGCAGGAATCGGTACGTTGGAGAAATGCTTTCAAAAGGTAT
GAGTCTAAAAACAATATTGGAACAGATGGTTATGGTAGCGGAAGGCGTTTACACGGCTAAAGCTGTGTATAACGACGCAA
AGGAAAAAGAAATTGAAATGCCCATAGCTTCGAAAATATATCAAGTATTATATGAAGGTGTAGATCCTAAAACGGCTATT
TACGAATTAATGACGAGGGATTTGAAATCTGAATTTTTTAATTGA

Upstream 100 bases:

>100_bases
GAGAAGGATGGTTAGTAAAACTAGACGATATAGCAAAAGCTTACAGAACCCCTTCTGTTAAAGAAGCTGTGAATACAATC
GCCAAGGAGCTGGAAAATTA

Downstream 100 bases:

>100_bases
AAGATATTATGGTATAATTAAATATGAAAGTTAAATTTTAAGTTTAAGGAGGCATTCGAATGCAAGTTTCTTTGGATCAG
CTTTTACAAGCATTAATGAT

Product: glycerol-3-phosphate dehydrogenase (NAD(P)(+))

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MPHITVLGAGSWGTAISKHLVDNDQKVTIWDRNKKLLQEIKEGRNSRYLPTLKLPSNDINVEGDINESLTNAQIVILAVP
VQHISEVLSKIHKSSLTNKEVIFVNLSKGIEINNRKIPSKIFEEYLSGFNYCTLSGPSHAEEVAENVPTSVVIGGIDDQV
NKYIQEIFSSETFRVYTNNDLIGVEISGAIKNIYAIGAGIIDGFGKWDNTKAALITRSLVEIIRYGTYYGGKKETFMGLA
GIGDLVVTCTSSHSRNRYVGEMLSKGMSLKTILEQMVMVAEGVYTAKAVYNDAKEKEIEMPIASKIYQVLYEGVDPKTAI
YELMTRDLKSEFFN

Sequences:

>Translated_334_residues
MPHITVLGAGSWGTAISKHLVDNDQKVTIWDRNKKLLQEIKEGRNSRYLPTLKLPSNDINVEGDINESLTNAQIVILAVP
VQHISEVLSKIHKSSLTNKEVIFVNLSKGIEINNRKIPSKIFEEYLSGFNYCTLSGPSHAEEVAENVPTSVVIGGIDDQV
NKYIQEIFSSETFRVYTNNDLIGVEISGAIKNIYAIGAGIIDGFGKWDNTKAALITRSLVEIIRYGTYYGGKKETFMGLA
GIGDLVVTCTSSHSRNRYVGEMLSKGMSLKTILEQMVMVAEGVYTAKAVYNDAKEKEIEMPIASKIYQVLYEGVDPKTAI
YELMTRDLKSEFFN
>Mature_333_residues
PHITVLGAGSWGTAISKHLVDNDQKVTIWDRNKKLLQEIKEGRNSRYLPTLKLPSNDINVEGDINESLTNAQIVILAVPV
QHISEVLSKIHKSSLTNKEVIFVNLSKGIEINNRKIPSKIFEEYLSGFNYCTLSGPSHAEEVAENVPTSVVIGGIDDQVN
KYIQEIFSSETFRVYTNNDLIGVEISGAIKNIYAIGAGIIDGFGKWDNTKAALITRSLVEIIRYGTYYGGKKETFMGLAG
IGDLVVTCTSSHSRNRYVGEMLSKGMSLKTILEQMVMVAEGVYTAKAVYNDAKEKEIEMPIASKIYQVLYEGVDPKTAIY
ELMTRDLKSEFFN

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=333, Percent_Identity=31.8318318318318, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI24307999, Length=332, Percent_Identity=28.9156626506024, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=36.5558912386707, Blast_Score=223, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI32564399, Length=310, Percent_Identity=31.2903225806452, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17507425, Length=336, Percent_Identity=28.8690476190476, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32564403, Length=317, Percent_Identity=30.2839116719243, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193210136, Length=317, Percent_Identity=30.2839116719243, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193210134, Length=307, Percent_Identity=28.9902280130293, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324513, Length=345, Percent_Identity=26.9565217391304, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320181, Length=342, Percent_Identity=28.6549707602339, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136204, Length=345, Percent_Identity=32.463768115942, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136200, Length=345, Percent_Identity=32.463768115942, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136202, Length=345, Percent_Identity=32.463768115942, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI22026922, Length=344, Percent_Identity=28.4883720930233, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI45551945, Length=265, Percent_Identity=30.5660377358491, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281362270, Length=265, Percent_Identity=30.5660377358491, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648969, Length=219, Percent_Identity=30.1369863013699, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_PETMO (A9BHX5)

Other databases:

- EMBL:   CP000879
- RefSeq:   YP_001568413.1
- ProteinModelPortal:   A9BHX5
- SMR:   A9BHX5
- GeneID:   5757989
- GenomeReviews:   CP000879_GR
- KEGG:   pmo:Pmob_1386
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   CLSK2541148
- BioCyc:   PMOB403833:PMOB_1386-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 37101; Mature: 36970

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 191-191 BINDING 108-108 BINDING 108-108 BINDING 140-140 BINDING 255-255 BINDING 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHITVLGAGSWGTAISKHLVDNDQKVTIWDRNKKLLQEIKEGRNSRYLPTLKLPSNDIN
CCEEEEEECCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCCCCEEEECCCCCCC
VEGDINESLTNAQIVILAVPVQHISEVLSKIHKSSLTNKEVIFVNLSKGIEINNRKIPSK
CCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCHH
IFEEYLSGFNYCTLSGPSHAEEVAENVPTSVVIGGIDDQVNKYIQEIFSSETFRVYTNND
HHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCC
LIGVEISGAIKNIYAIGAGIIDGFGKWDNTKAALITRSLVEIIRYGTYYGGKKETFMGLA
EEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHEECC
GIGDLVVTCTSSHSRNRYVGEMLSKGMSLKTILEQMVMVAEGVYTAKAVYNDAKEKEIEM
CCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCC
PIASKIYQVLYEGVDPKTAIYELMTRDLKSEFFN
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PHITVLGAGSWGTAISKHLVDNDQKVTIWDRNKKLLQEIKEGRNSRYLPTLKLPSNDIN
CEEEEEECCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCCCCEEEECCCCCCC
VEGDINESLTNAQIVILAVPVQHISEVLSKIHKSSLTNKEVIFVNLSKGIEINNRKIPSK
CCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCHH
IFEEYLSGFNYCTLSGPSHAEEVAENVPTSVVIGGIDDQVNKYIQEIFSSETFRVYTNND
HHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCC
LIGVEISGAIKNIYAIGAGIIDGFGKWDNTKAALITRSLVEIIRYGTYYGGKKETFMGLA
EEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHEECC
GIGDLVVTCTSSHSRNRYVGEMLSKGMSLKTILEQMVMVAEGVYTAKAVYNDAKEKEIEM
CCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHCCHHHHHCCC
PIASKIYQVLYEGVDPKTAIYELMTRDLKSEFFN
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA