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The map label for this gene is trxB [H]

Identifier: 160902043

GI number: 160902043

Start: 617836

End: 618858

Strand: Direct

Name: trxB [H]

Synonym: Pmob_0567

Alternate gene names: 160902043

Gene position: 617836-618858 (Clockwise)

Preceding gene: 160902042

Following gene: 160902044

Centisome position: 28.48

GC content: 35.97

Gene sequence:

>1023_bases
ATGTTTTTTAACGTTGAAGGGGCTAACAAAAAATCCGAAATAAAACAACAATATGACGTTGTAATAATCGGTGGCGGTCC
TGCCGGGATTTCAGCTGCTATATATGCCTTACAAGGCGGAGCTTCTACCCTGGTAATTGAAAAAGCAATTGAAGGCGGAC
AAATGAATTTAACAGATATTATAGAAAATTACCCAGGGTTTAAAACGATAAAGGGTGAAGAGCTATCTTCTTTGATGAAA
GAGCACGCAGAGCAGTTCGGAGCCGACTTCTATGATGGGAAAGTTATAGAATTGATAGACAGCCTTACGGCAGATAAGGA
TGAAGATTTCCACAAAATGGTTGTTATGGAAAATGGAAAAACAATCAAATCAAAGGCAATAATAATAGCAAGCGGATCTT
ACCCTCGAAAATTAGGGGTTAAAGGTGAAGAGGAATTTTCTTCCAGAGGTGTTTCTTACTGTGCATCGTGCGATGGTCAT
TTTTTTAAGAATAAAAAAATTGCTGTCGTGGGAGGAGGAAATACAGCCGTAGAGGAAGCGGTTTATTTATCGAACATAGC
TAAAGAAGTTTATATAATTCACAGAAGAGAAAAACTTAGAGCTGATAAACTTTATCAAGATAGAGCCTTTTCTCGTAATA
ACATAAAGTTTAAATGGAATTCGGTCATTGAAGAAATTAAAGGCAAAGATAAGGTCGAAAGTTTGGTCATTAAAAATCTA
AAAAACGATGAAGTTTATGAAGAACCTTTCGATGGAGTTTTTGTTTTCGTTGGATTAGTGCCAGAAACAAGCTTTTTAAA
TAAAGATCTTTTCGATTTTGACGAATATGGTTTCTTAATTACAGACGAGAATATGGAAACAAAAGTTAAGGGTATTTATG
CAGTAGGAGATGTAAGAAAAAAGGAGCTCAGACAAATTGTAACTGCGGTGTCCGATGGAGCTATAGCTGCTTCACATGCA
ATTCGCGAGTACGTTAATGAAGACCAAATATCATCAACTCAATCGATAAATTTGACAAAATGA

Upstream 100 bases:

>100_bases
TGGGTAAAAAAAGGTGAGTTTGTGGGAGCCTACCCTGAAAATAGTTTTGTGGAAGAAGTTTTAAAAGCAGTTGAATAAAG
TAGTTGAAGGAGGTTCTCAG

Downstream 100 bases:

>100_bases
AGATATAATTGTATAATATGTTTAGTACCTTTAACTCAGTTTAGGGTGTAACCCCTTTTCTTGGTTAAAGGAATATTCTG
CAGGAGGTTATAGAAAAGAT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MFFNVEGANKKSEIKQQYDVVIIGGGPAGISAAIYALQGGASTLVIEKAIEGGQMNLTDIIENYPGFKTIKGEELSSLMK
EHAEQFGADFYDGKVIELIDSLTADKDEDFHKMVVMENGKTIKSKAIIIASGSYPRKLGVKGEEEFSSRGVSYCASCDGH
FFKNKKIAVVGGGNTAVEEAVYLSNIAKEVYIIHRREKLRADKLYQDRAFSRNNIKFKWNSVIEEIKGKDKVESLVIKNL
KNDEVYEEPFDGVFVFVGLVPETSFLNKDLFDFDEYGFLITDENMETKVKGIYAVGDVRKKELRQIVTAVSDGAIAASHA
IREYVNEDQISSTQSINLTK

Sequences:

>Translated_340_residues
MFFNVEGANKKSEIKQQYDVVIIGGGPAGISAAIYALQGGASTLVIEKAIEGGQMNLTDIIENYPGFKTIKGEELSSLMK
EHAEQFGADFYDGKVIELIDSLTADKDEDFHKMVVMENGKTIKSKAIIIASGSYPRKLGVKGEEEFSSRGVSYCASCDGH
FFKNKKIAVVGGGNTAVEEAVYLSNIAKEVYIIHRREKLRADKLYQDRAFSRNNIKFKWNSVIEEIKGKDKVESLVIKNL
KNDEVYEEPFDGVFVFVGLVPETSFLNKDLFDFDEYGFLITDENMETKVKGIYAVGDVRKKELRQIVTAVSDGAIAASHA
IREYVNEDQISSTQSINLTK
>Mature_340_residues
MFFNVEGANKKSEIKQQYDVVIIGGGPAGISAAIYALQGGASTLVIEKAIEGGQMNLTDIIENYPGFKTIKGEELSSLMK
EHAEQFGADFYDGKVIELIDSLTADKDEDFHKMVVMENGKTIKSKAIIIASGSYPRKLGVKGEEEFSSRGVSYCASCDGH
FFKNKKIAVVGGGNTAVEEAVYLSNIAKEVYIIHRREKLRADKLYQDRAFSRNNIKFKWNSVIEEIKGKDKVESLVIKNL
KNDEVYEEPFDGVFVFVGLVPETSFLNKDLFDFDEYGFLITDENMETKVKGIYAVGDVRKKELRQIVTAVSDGAIAASHA
IREYVNEDQISSTQSINLTK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=327, Percent_Identity=24.1590214067278, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI226437568, Length=327, Percent_Identity=24.1590214067278, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI21389617, Length=327, Percent_Identity=24.1590214067278, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1787114, Length=316, Percent_Identity=36.0759493670886, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI87081763, Length=307, Percent_Identity=33.2247557003257, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6320560, Length=312, Percent_Identity=34.2948717948718, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=34.0694006309148, Blast_Score=163, Evalue=4e-41,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 37782; Mature: 37782

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFNVEGANKKSEIKQQYDVVIIGGGPAGISAAIYALQGGASTLVIEKAIEGGQMNLTDI
CEEECCCCCCHHHHHHHCCEEEECCCCCCHHHHHEEECCCCCEEEEEECCCCCCCCHHHH
IENYPGFKTIKGEELSSLMKEHAEQFGADFYDGKVIELIDSLTADKDEDFHKMVVMENGK
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCC
TIKSKAIIIASGSYPRKLGVKGEEEFSSRGVSYCASCDGHFFKNKKIAVVGGGNTAVEEA
EEEEEEEEEECCCCCCCCCCCCCHHHHHCCCHHHHCCCCCEECCCEEEEEECCCHHHHHH
VYLSNIAKEVYIIHRREKLRADKLYQDRAFSRNNIKFKWNSVIEEIKGKDKVESLVIKNL
HHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHCC
KNDEVYEEPFDGVFVFVGLVPETSFLNKDLFDFDEYGFLITDENMETKVKGIYAVGDVRK
CCCCHHHCCCCCEEEEEEECCCHHHHCCCCCCHHHCCEEEECCCCCCHHEEEEEECHHHH
KELRQIVTAVSDGAIAASHAIREYVNEDQISSTQSINLTK
HHHHHHHHHHCCCCHHHHHHHHHHHCHHHCCCCCCEECCC
>Mature Secondary Structure
MFFNVEGANKKSEIKQQYDVVIIGGGPAGISAAIYALQGGASTLVIEKAIEGGQMNLTDI
CEEECCCCCCHHHHHHHCCEEEECCCCCCHHHHHEEECCCCCEEEEEECCCCCCCCHHHH
IENYPGFKTIKGEELSSLMKEHAEQFGADFYDGKVIELIDSLTADKDEDFHKMVVMENGK
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCC
TIKSKAIIIASGSYPRKLGVKGEEEFSSRGVSYCASCDGHFFKNKKIAVVGGGNTAVEEA
EEEEEEEEEECCCCCCCCCCCCCHHHHHCCCHHHHCCCCCEECCCEEEEEECCCHHHHHH
VYLSNIAKEVYIIHRREKLRADKLYQDRAFSRNNIKFKWNSVIEEIKGKDKVESLVIKNL
HHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHCC
KNDEVYEEPFDGVFVFVGLVPETSFLNKDLFDFDEYGFLITDENMETKVKGIYAVGDVRK
CCCCHHHCCCCCEEEEEEECCCHHHHCCCCCCHHHCCEEEECCCCCCHHEEEEEECHHHH
KELRQIVTAVSDGAIAASHAIREYVNEDQISSTQSINLTK
HHHHHHHHHHCCCCHHHHHHHHHHHCHHHCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]