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The map label for this gene is ugd [H]

Identifier: 160877569

GI number: 160877569

Start: 5278373

End: 5279536

Strand: Direct

Name: ugd [H]

Synonym: Sbal195_4468

Alternate gene names: 160877569

Gene position: 5278373-5279536 (Clockwise)

Preceding gene: 160877565

Following gene: 160877570

Centisome position: 98.71

GC content: 43.3

Gene sequence:

>1164_bases
ATGGATATTGTTGTTGTGGGGATGGGCTATGTTGGCCTATCAAATGCAGTCTTATTGGCGCAGCAAAATCGAGTTACTGC
AATTGATTTAGTTCCTGAACGTGTCAAGCAAGTTAACGAGCGTAAATCCACTGTGGTCGATGAATTAATCGAAGATTACC
TGCAAAACAAACCGTTGAATTTAACTGCGACAACGGAAAATGTAGCCTTTCAATCGGCTGACTTTGTGATTATTGCGACT
CCAACAGACTACGATCCTCAGACTAATTATTTTAATACCCATTCGGTTGAAAGCGTCATTCGTGATGTACTCGCAGTTAA
TCCTGATACGACGATTATCATCAAATCGACTGTACCCGTCGGCTATACCACTGCATTAAGGCACAAGTTTAAGAGCGACA
ACATACTCTTTTCTCCAGAGTTTTTACGCGAAGGGAAAGCCTTGCATGACAACCTTCATCCCTCACGGATCGTCGTCGGT
GAACGCTCGGCGCGTGCCCAAGTCTTTGCAGACCTTTTAGCCAAGGCGGCAATCAAGCAAGATATTCCTATTTTGCTGAC
CGATAGCACCGAAGCCGAAGCGATTAAGTTATTTGCTAATACATTTCTCGCCATGCGGGTCGCCTACTTTAACGAACTCG
ATACCTATGCAGAGAGTCGAGGATTAAATACTCGCCAGATTATTGAGGGGGTTAGCCTCGATCCGCGTATTGGTGATTAT
TACAACAATCCTTCTTTTGGCTATGGCGGGTACTGTCTTCCGAAAGACACTAAGCAATTACTGGCTAACTACAATGATGT
CCCAAACAATTTAATCAGTGCCATTGTCGACTCAAACACCACACGAAAAGACTTTATCGCCGACGCTATTATCCGTAAGC
AGCCAAAATGTGTAGGAATTTATCGTTTGATCATGAAAGCCGATTCAGACAATTTCCGCGCCTCAGCAGTGCAAGGCGTG
ATGAAGCGCATTAAAGCGAAAGGCATTGAAGTCGTCGTGTTTGAGCCTGTACTTAAAGAAGATTACTTTTTCAAATCTCG
CGTGATGAGAGACTTAACTGAATTTAAGTCAATATGTGATGTGATCGTCTCCAACCGTATGGTTGATGAACTCAATGATG
TTGCGGATAAAGTCTATACCCGAGATCTATTTCACCATGATTAA

Upstream 100 bases:

>100_bases
CAGCACTTAATTTGGAACTGTGGATTTCATAGTATGGACATATTTATCGATAAAATAAGTGTTAGTTTATTAAGCAGAAC
GCATAACCTTAAAATAATCT

Downstream 100 bases:

>100_bases
TACACTTTAAATAAAGGTCATAAATGAAATACTTAGTCACAGGCGCTGCGGGTTTTATCGGCGCCAAAGTCAGTGAACGC
CTTTGCTTGCTTGGCCATGA

Product: UDP-glucose/GDP-mannose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MDIVVVGMGYVGLSNAVLLAQQNRVTAIDLVPERVKQVNERKSTVVDELIEDYLQNKPLNLTATTENVAFQSADFVIIAT
PTDYDPQTNYFNTHSVESVIRDVLAVNPDTTIIIKSTVPVGYTTALRHKFKSDNILFSPEFLREGKALHDNLHPSRIVVG
ERSARAQVFADLLAKAAIKQDIPILLTDSTEAEAIKLFANTFLAMRVAYFNELDTYAESRGLNTRQIIEGVSLDPRIGDY
YNNPSFGYGGYCLPKDTKQLLANYNDVPNNLISAIVDSNTTRKDFIADAIIRKQPKCVGIYRLIMKADSDNFRASAVQGV
MKRIKAKGIEVVVFEPVLKEDYFFKSRVMRDLTEFKSICDVIVSNRMVDELNDVADKVYTRDLFHHD

Sequences:

>Translated_387_residues
MDIVVVGMGYVGLSNAVLLAQQNRVTAIDLVPERVKQVNERKSTVVDELIEDYLQNKPLNLTATTENVAFQSADFVIIAT
PTDYDPQTNYFNTHSVESVIRDVLAVNPDTTIIIKSTVPVGYTTALRHKFKSDNILFSPEFLREGKALHDNLHPSRIVVG
ERSARAQVFADLLAKAAIKQDIPILLTDSTEAEAIKLFANTFLAMRVAYFNELDTYAESRGLNTRQIIEGVSLDPRIGDY
YNNPSFGYGGYCLPKDTKQLLANYNDVPNNLISAIVDSNTTRKDFIADAIIRKQPKCVGIYRLIMKADSDNFRASAVQGV
MKRIKAKGIEVVVFEPVLKEDYFFKSRVMRDLTEFKSICDVIVSNRMVDELNDVADKVYTRDLFHHD
>Mature_387_residues
MDIVVVGMGYVGLSNAVLLAQQNRVTAIDLVPERVKQVNERKSTVVDELIEDYLQNKPLNLTATTENVAFQSADFVIIAT
PTDYDPQTNYFNTHSVESVIRDVLAVNPDTTIIIKSTVPVGYTTALRHKFKSDNILFSPEFLREGKALHDNLHPSRIVVG
ERSARAQVFADLLAKAAIKQDIPILLTDSTEAEAIKLFANTFLAMRVAYFNELDTYAESRGLNTRQIIEGVSLDPRIGDY
YNNPSFGYGGYCLPKDTKQLLANYNDVPNNLISAIVDSNTTRKDFIADAIIRKQPKCVGIYRLIMKADSDNFRASAVQGV
MKRIKAKGIEVVVFEPVLKEDYFFKSRVMRDLTEFKSICDVIVSNRMVDELNDVADKVYTRDLFHHD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=367, Percent_Identity=25.6130790190736, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI296040438, Length=242, Percent_Identity=27.6859504132231, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI296040443, Length=216, Percent_Identity=27.3148148148148, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=69.5876288659794, Blast_Score=577, Evalue=1e-166,
Organism=Escherichia coli, GI48994968, Length=374, Percent_Identity=24.5989304812834, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560350, Length=403, Percent_Identity=26.5508684863524, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI17136908, Length=383, Percent_Identity=26.1096605744125, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43502; Mature: 43502

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVVVGMGYVGLSNAVLLAQQNRVTAIDLVPERVKQVNERKSTVVDELIEDYLQNKPLN
CCEEEEECCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LTATTENVAFQSADFVIIATPTDYDPQTNYFNTHSVESVIRDVLAVNPDTTIIIKSTVPV
EEEECCCCEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
GYTTALRHKFKSDNILFSPEFLREGKALHDNLHPSRIVVGERSARAQVFADLLAKAAIKQ
CHHHHHHHHHCCCCEEECHHHHHCCCHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHC
DIPILLTDSTEAEAIKLFANTFLAMRVAYFNELDTYAESRGLNTRQIIEGVSLDPRIGDY
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
YNNPSFGYGGYCLPKDTKQLLANYNDVPNNLISAIVDSNTTRKDFIADAIIRKQPKCVGI
CCCCCCCCCCEECCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHH
YRLIMKADSDNFRASAVQGVMKRIKAKGIEVVVFEPVLKEDYFFKSRVMRDLTEFKSICD
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
VIVSNRMVDELNDVADKVYTRDLFHHD
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIVVVGMGYVGLSNAVLLAQQNRVTAIDLVPERVKQVNERKSTVVDELIEDYLQNKPLN
CCEEEEECCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LTATTENVAFQSADFVIIATPTDYDPQTNYFNTHSVESVIRDVLAVNPDTTIIIKSTVPV
EEEECCCCEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
GYTTALRHKFKSDNILFSPEFLREGKALHDNLHPSRIVVGERSARAQVFADLLAKAAIKQ
CHHHHHHHHHCCCCEEECHHHHHCCCHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHC
DIPILLTDSTEAEAIKLFANTFLAMRVAYFNELDTYAESRGLNTRQIIEGVSLDPRIGDY
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCC
YNNPSFGYGGYCLPKDTKQLLANYNDVPNNLISAIVDSNTTRKDFIADAIIRKQPKCVGI
CCCCCCCCCCEECCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHH
YRLIMKADSDNFRASAVQGVMKRIKAKGIEVVVFEPVLKEDYFFKSRVMRDLTEFKSICD
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
VIVSNRMVDELNDVADKVYTRDLFHHD
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]