Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 160876655

GI number: 160876655

Start: 4172116

End: 4173762

Strand: Direct

Name: hlyB [H]

Synonym: Sbal195_3549

Alternate gene names: 160876655

Gene position: 4172116-4173762 (Clockwise)

Preceding gene: 160876654

Following gene: 160876657

Centisome position: 78.02

GC content: 48.57

Gene sequence:

>1647_bases
ATGGAATGGTATAAAGATCTTTCCGTTAACCAGAAACTGACTTACCCGAGTCTGCTACTCGCTGGCGTAGTCATCTTCGC
CTCTTCAACTGGCATCTTAGGGCTTAAAGCATTAAATAACAGCGCAAATACGCTCGCACTCGAATACTTACCGAGCCAAT
CTGAACTGCTGCAAGCTGATAAAGAGCTTTACCAAGCGCAAGTCGCCGAACGTAGCCTGATGTTCGTTAACGTGGGCACG
GACTCCTATAATAGCCTTCTAAAACAGCACACTAATAGTATATCCCTAGTCAAAGAACACCTTAATCAGTTTGCTGATGT
GACCACTAGTCCCCTCGCAAAAGAAAAACTCAATGAATTAAATCGCAGTTTCGAGGTATGGCGAACCACTACCTCTGAAA
TCAGCAATCAGCGCACCCAAAATGGCCGTAACGGTCGCACGACCGCCATTGATCTGAGCTTTGGCCAAGCAGCGACGCAA
TTCGAGCAGCTGCATCAAAATATTAATCAGCTGATCGATGACTTAAACAGCAATACGGCAGCAGCTGTCACCCAAGTGGA
TGATGACGCCTATCGTGGACAGCAGATGCAGTTAATTGCTTTAACGATTAGTATCCTGATCTGCATTCTATTCATCGTTG
CCTTGCCTAAACTCATCAGTAAGCCGCTCGCAGTTTTGCTCGCGAAAATCCACGACATTACCGATGGTGATGGCGATTTG
ACCGAGCGAATCCAGCTAACCTCTAAGGACGAACTGGGCGATCTTGCCAATGCCTTCAATCACTTCCTCGATAATTTACA
CGGCATTATCTCGCAGTTTAAACAATCTACTTCGGAGCTGAATGTCGCCGCCGAAGGGCTAGCCAAAACCAGTGCCACGG
CAAAACATACCTTGATGGATCAACAGGCGGCCACCCATAGAATCGCCGATGCCAGTGATCACATTGCTGCCTCAGTGCAA
GAAGTGTCTGTCAGTGCCAGTCATGCCGCCGATGCCGCGAAACAAGCCGATGTCTTTACCGCCGATGGCCAAGAGAGAGT
GAAAAAAACCATCAATGTAATTCGTGAACTCGCAGGAGATGTAGGCTCAGCCGAAATGCAGATCAACAAACTCGAACAAG
AAGGCCAACATATCGGCCGCGTGCTTGAGGTGATCCAATCTATTGCCGAGCAGACGAATCTATTAGCCCTTAACGCAGCG
ATTGAAGCGGCGCGAGCGGGCGAACAAGGACGCGGCTTTGCTGTGGTTGCCGATGAAGTGCGCTCCCTCGCCTCTAAGAC
CCACCAATCCACCGAAGAAATTAAATTGATGATCGCCAATGTGCAAAATGGCACCCAAAGCGCTGTGGCGGCAATTAATA
TCGGTAATGAAAAGGCCATTTCAAGCGTCGAAGCCGCCAGTAATGCCGGTGAAGCCCTAGCGCATATTGCAGAAATGGTG
AGTCAGATCAGCGAAATGAATAATCAAATAGCCCTCGCTGCCAAAGCGCAAACCACTATGGCCAATGAGAGTCATCAAAA
TATTCAACACATTGCCGAACAGTCGGAGGACAGTTTACGCAACACTGATGAAATCTACGCCGCAAGCGTACAACTCTCGT
CAATGGCGGGTAACCTCACGGCGCTAGTCAGTCGTTTTAAACTGTAA

Upstream 100 bases:

>100_bases
TCTAATTGCCAGAGAACGCCAGTGATGGGCCGCATCCGCTTTTATTCAGTGGTTATCGCGGCCCTCACCTTTCAATGCAT
CAATCAAGGAGGGCGTGACT

Downstream 100 bases:

>100_bases
TTTGTTGAGAGTGAAAGTTTTTATATAAGTTACCTTTTGTAAATCAGTGATGTTTGAAAAGTCCCCTATACCGAATAAGG
GAGCATAAACCTGTCGCAGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MEWYKDLSVNQKLTYPSLLLAGVVIFASSTGILGLKALNNSANTLALEYLPSQSELLQADKELYQAQVAERSLMFVNVGT
DSYNSLLKQHTNSISLVKEHLNQFADVTTSPLAKEKLNELNRSFEVWRTTTSEISNQRTQNGRNGRTTAIDLSFGQAATQ
FEQLHQNINQLIDDLNSNTAAAVTQVDDDAYRGQQMQLIALTISILICILFIVALPKLISKPLAVLLAKIHDITDGDGDL
TERIQLTSKDELGDLANAFNHFLDNLHGIISQFKQSTSELNVAAEGLAKTSATAKHTLMDQQAATHRIADASDHIAASVQ
EVSVSASHAADAAKQADVFTADGQERVKKTINVIRELAGDVGSAEMQINKLEQEGQHIGRVLEVIQSIAEQTNLLALNAA
IEAARAGEQGRGFAVVADEVRSLASKTHQSTEEIKLMIANVQNGTQSAVAAINIGNEKAISSVEAASNAGEALAHIAEMV
SQISEMNNQIALAAKAQTTMANESHQNIQHIAEQSEDSLRNTDEIYAASVQLSSMAGNLTALVSRFKL

Sequences:

>Translated_548_residues
MEWYKDLSVNQKLTYPSLLLAGVVIFASSTGILGLKALNNSANTLALEYLPSQSELLQADKELYQAQVAERSLMFVNVGT
DSYNSLLKQHTNSISLVKEHLNQFADVTTSPLAKEKLNELNRSFEVWRTTTSEISNQRTQNGRNGRTTAIDLSFGQAATQ
FEQLHQNINQLIDDLNSNTAAAVTQVDDDAYRGQQMQLIALTISILICILFIVALPKLISKPLAVLLAKIHDITDGDGDL
TERIQLTSKDELGDLANAFNHFLDNLHGIISQFKQSTSELNVAAEGLAKTSATAKHTLMDQQAATHRIADASDHIAASVQ
EVSVSASHAADAAKQADVFTADGQERVKKTINVIRELAGDVGSAEMQINKLEQEGQHIGRVLEVIQSIAEQTNLLALNAA
IEAARAGEQGRGFAVVADEVRSLASKTHQSTEEIKLMIANVQNGTQSAVAAINIGNEKAISSVEAASNAGEALAHIAEMV
SQISEMNNQIALAAKAQTTMANESHQNIQHIAEQSEDSLRNTDEIYAASVQLSSMAGNLTALVSRFKL
>Mature_548_residues
MEWYKDLSVNQKLTYPSLLLAGVVIFASSTGILGLKALNNSANTLALEYLPSQSELLQADKELYQAQVAERSLMFVNVGT
DSYNSLLKQHTNSISLVKEHLNQFADVTTSPLAKEKLNELNRSFEVWRTTTSEISNQRTQNGRNGRTTAIDLSFGQAATQ
FEQLHQNINQLIDDLNSNTAAAVTQVDDDAYRGQQMQLIALTISILICILFIVALPKLISKPLAVLLAKIHDITDGDGDL
TERIQLTSKDELGDLANAFNHFLDNLHGIISQFKQSTSELNVAAEGLAKTSATAKHTLMDQQAATHRIADASDHIAASVQ
EVSVSASHAADAAKQADVFTADGQERVKKTINVIRELAGDVGSAEMQINKLEQEGQHIGRVLEVIQSIAEQTNLLALNAA
IEAARAGEQGRGFAVVADEVRSLASKTHQSTEEIKLMIANVQNGTQSAVAAINIGNEKAISSVEAASNAGEALAHIAEMV
SQISEMNNQIALAAKAQTTMANESHQNIQHIAEQSEDSLRNTDEIYAASVQLSSMAGNLTALVSRFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=356, Percent_Identity=27.5280898876405, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI2367378, Length=314, Percent_Identity=28.9808917197452, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1788194, Length=530, Percent_Identity=25.4716981132075, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788195, Length=359, Percent_Identity=29.2479108635098, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1789453, Length=261, Percent_Identity=30.6513409961686, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59176; Mature: 59176

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWYKDLSVNQKLTYPSLLLAGVVIFASSTGILGLKALNNSANTLALEYLPSQSELLQAD
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEEEECCCHHHHHHHH
KELYQAQVAERSLMFVNVGTDSYNSLLKQHTNSISLVKEHLNQFADVTTSPLAKEKLNEL
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NRSFEVWRTTTSEISNQRTQNGRNGRTTAIDLSFGQAATQFEQLHQNINQLIDDLNSNTA
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCC
AAVTQVDDDAYRGQQMQLIALTISILICILFIVALPKLISKPLAVLLAKIHDITDGDGDL
EEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
TERIQLTSKDELGDLANAFNHFLDNLHGIISQFKQSTSELNVAAEGLAKTSATAKHTLMD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQAATHRIADASDHIAASVQEVSVSASHAADAAKQADVFTADGQERVKKTINVIRELAGD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCC
VGSAEMQINKLEQEGQHIGRVLEVIQSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEEHHHH
RSLASKTHQSTEEIKLMIANVQNGTQSAVAAINIGNEKAISSVEAASNAGEALAHIAEMV
HHHHHHHHCCHHHHHHHHEECCCCCCHHEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHH
SQISEMNNQIALAAKAQTTMANESHQNIQHIAEQSEDSLRNTDEIYAASVQLSSMAGNLT
HHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHEEHHHHHHHHH
ALVSRFKL
HHHHHHCC
>Mature Secondary Structure
MEWYKDLSVNQKLTYPSLLLAGVVIFASSTGILGLKALNNSANTLALEYLPSQSELLQAD
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHCCCCCEEEEEECCCHHHHHHHH
KELYQAQVAERSLMFVNVGTDSYNSLLKQHTNSISLVKEHLNQFADVTTSPLAKEKLNEL
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NRSFEVWRTTTSEISNQRTQNGRNGRTTAIDLSFGQAATQFEQLHQNINQLIDDLNSNTA
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCC
AAVTQVDDDAYRGQQMQLIALTISILICILFIVALPKLISKPLAVLLAKIHDITDGDGDL
EEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
TERIQLTSKDELGDLANAFNHFLDNLHGIISQFKQSTSELNVAAEGLAKTSATAKHTLMD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQAATHRIADASDHIAASVQEVSVSASHAADAAKQADVFTADGQERVKKTINVIRELAGD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCC
VGSAEMQINKLEQEGQHIGRVLEVIQSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEEHHHH
RSLASKTHQSTEEIKLMIANVQNGTQSAVAAINIGNEKAISSVEAASNAGEALAHIAEMV
HHHHHHHHCCHHHHHHHHEECCCCCCHHEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHH
SQISEMNNQIALAAKAQTTMANESHQNIQHIAEQSEDSLRNTDEIYAASVQLSSMAGNLT
HHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHEEHHHHHHHHH
ALVSRFKL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]