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The map label for this gene is purP [H]

Identifier: 160876649

GI number: 160876649

Start: 4165238

End: 4166527

Strand: Reverse

Name: purP [H]

Synonym: Sbal195_3543

Alternate gene names: 160876649

Gene position: 4166527-4165238 (Counterclockwise)

Preceding gene: 160876650

Following gene: 160876648

Centisome position: 77.92

GC content: 49.15

Gene sequence:

>1290_bases
ATGTTAGAAAAACTGTTCAAACTGAAACAAAATCAAACGAGCCTCAAGCAGGAAGCTGTCGCTGGTTTGACAACATTTAT
GACCATGGCCTACATCATTTTTGTGAATCCAATGATGTTAGCCGATGCGGGCATGGACCATGGGGCTGTATTCGTAGCGA
CTTGTTTGGCTGCGGCTGTCGGCTGTTTAGTCATGGGCTTGATGGCAAATTATCCTATCGCGCTTGCACCTGGCATGGGG
CTGAACGCCTTTTTTACCTACACAGTTGTGGGTGAGATGGGTTACAGCTGGGAGACAGCACTTGGCGCGGTATTCCTGTC
GGGTATTTGCTTTTTAATCTTATCTTTAGTGCGCATTCGAGAGTGGATTGTGAATAGCATTCCAATGTCGCTGCGTATTG
GTATTGCTGCTGGTATTGGTCTGTTCCTTGCGCTGATCGGCCTTAAGAGTGCCGGTATTGTGGTGGCAAGCCCCGCAACC
TTAGTGACCTTAGGCGATATCACTGCATTTCCGGCTGTCATGGCTGTGTTAGGTTTTTTCCTGATCATTGCTATGGTGCA
ACGTGGAATGAAGTCGGCGGTTATCCTAAGTATCTTGATTATCACAGGGCTGGGATTAGTGTTTGGCGATGTGCAGTATC
ACGGCATTGTGTCTATGCCGCCGTCGATCATGCCAACCTTTTTGAAGATGGATTTATCCCAAGTCTTTGAAGTCAGCATG
TTATCTGTGGTGTTTGCCTTCTTATTCGTCGATCTTTTCGATACCTCTGGCACTTTAGTTGCGGTTGCGCAGCGCGGTGG
TTTCCTCGATGAGAAGGGCCGTTTACCGCGCTTGAACCGTGCCTTAACCGCCGACAGTTTAGCGACTATTGCGGGCGCGG
CTTTTGGTACATCGACGACAACAAGTTATATCGAAAGTACGGCGGGTGTGAGCGCGGGTGGTCGTACTGGTTTGACGGCA
GTTGTCGTGGGATTACTCTTTATTGCTGCGTTATTCCTGTCGCCATTGGCGGGCATGATCCCAGCGTATGCGACGGCGGG
TACACTGTTTTATGTGGCGATTCTGATGATGTCAGGACTCGTGCATGTCGAATGGGAAGATTTGACTGAAGCCGCACCGG
TAGTCGTTGTGTGTATTTTAATGCCGCTGACGTTTTCCATCGCGACAGGCATCGCCTTTGGGATGATCTCTTACGCCGCA
ATCAAATTACTCACAGGTCGTTTTAGCGATCTCAATGTGGGCATTGTCGTCTTGGCTGCGCTGTTTGTAGCTAAGTTTAT
CTATGGCTAA

Upstream 100 bases:

>100_bases
CCAGCCTAAACTCCCTATAATCGGCTGCAAATGTCATCACGCTACATAGTGTTTACATCTAACTACCCTACATACTTAAA
ATAAAAAGGAACCTTGTTCC

Downstream 100 bases:

>100_bases
TCCTATCGATTCGTGACTCGTGCAGTGCGAGCTCACAACGTAGATTGTCTACAATAGACAATATTTTTTGAGGGTCATCT
CATCGATGGCCCTTTTTCAT

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLEKLFKLKQNQTSLKQEAVAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAVGCLVMGLMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIREWIVNSIPMSLRIGIAAGIGLFLALIGLKSAGIVVASPAT
LVTLGDITAFPAVMAVLGFFLIIAMVQRGMKSAVILSILIITGLGLVFGDVQYHGIVSMPPSIMPTFLKMDLSQVFEVSM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAAFGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFIAALFLSPLAGMIPAYATAGTLFYVAILMMSGLVHVEWEDLTEAAPVVVVCILMPLTFSIATGIAFGMISYAA
IKLLTGRFSDLNVGIVVLAALFVAKFIYG

Sequences:

>Translated_429_residues
MLEKLFKLKQNQTSLKQEAVAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAVGCLVMGLMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIREWIVNSIPMSLRIGIAAGIGLFLALIGLKSAGIVVASPAT
LVTLGDITAFPAVMAVLGFFLIIAMVQRGMKSAVILSILIITGLGLVFGDVQYHGIVSMPPSIMPTFLKMDLSQVFEVSM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAAFGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFIAALFLSPLAGMIPAYATAGTLFYVAILMMSGLVHVEWEDLTEAAPVVVVCILMPLTFSIATGIAFGMISYAA
IKLLTGRFSDLNVGIVVLAALFVAKFIYG
>Mature_429_residues
MLEKLFKLKQNQTSLKQEAVAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAVGCLVMGLMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIREWIVNSIPMSLRIGIAAGIGLFLALIGLKSAGIVVASPAT
LVTLGDITAFPAVMAVLGFFLIIAMVQRGMKSAVILSILIITGLGLVFGDVQYHGIVSMPPSIMPTFLKMDLSQVFEVSM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAAFGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFIAALFLSPLAGMIPAYATAGTLFYVAILMMSGLVHVEWEDLTEAAPVVVVCILMPLTFSIATGIAFGMISYAA
IKLLTGRFSDLNVGIVVLAALFVAKFIYG

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=428, Percent_Identity=51.1682242990654, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI87082309, Length=426, Percent_Identity=49.5305164319249, Blast_Score=450, Evalue=1e-128,
Organism=Escherichia coli, GI1790499, Length=435, Percent_Identity=38.1609195402299, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI48994909, Length=435, Percent_Identity=38.3908045977011, Blast_Score=266, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45067; Mature: 45067

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCC
>Mature Secondary Structure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HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]