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The map label for this gene is pilE [H]

Identifier: 160876492

GI number: 160876492

Start: 4008123

End: 4009439

Strand: Direct

Name: pilE [H]

Synonym: Sbal195_3386

Alternate gene names: 160876492

Gene position: 4008123-4009439 (Clockwise)

Preceding gene: 160876491

Following gene: 160876493

Centisome position: 74.96

GC content: 45.33

Gene sequence:

>1317_bases
ATGAACGCTCAAATATTACGAAAAAACAATAATCGAGGCTTCAACTTGTTAGAGATAATGGTTGTTGTAGCGATTATTGG
AATACTCGCGGTTGTGGCGGTTCCTTTGTATAAAGATTACATAATACGTGCGCAGGTTACAGAAGCTTTTGTTTTTGCCG
ATGCGGAAAGAATTAAAGTCATTGAAAAACGTATTGAAAGCACCAACGTTGATATTGCAACATTCTCTGAACCAAAAGTA
CATATGACTTCTTTGATGTGGGTGCCTGTAATAAATAACCAACCAGTCGAAAATTCGGTTATCGGATATATTCTTCCCAC
TATGGATTTAAAAGGTCTTGGGGTGAGAGATACGTTTGCGCTTGAGTATTTTTACAATGGCTCTTGGCGTTGCGTTAATG
CTGCCAATGCGATTGGTCGCGATGCAGTGTCTACCAATAAAGCGCTTGATGACAAGTACCTCCCAAGTAGCTGTCGTACC
GGAGCCGGCTTGTTGGCGGCACATCCTAAGGCTCCTGCGGGCTGCCCCCCTGGGACTCAAAAAGCACAAGTGAAAGATGC
TAGCGGGAAACAGCAGCAAGTCTGCCAGCGACCTAAGCCTCAGGTACAACCGCAGGCACAACCTCAGGCACAACCGCAGG
CTCAACCTCAGGCACAACCTCAGGCACAACCTCAGGCACAACCTCAGGTGAAACCTCAGGCTGTGGTTAAGCCCCCCTCC
TGTCCTATAGGCCAAGACTGTAGCCATAAGGATCCTAAATGTTCAGTAGCGGGACAAGAACACATAGATCAAACCTCGGT
TCCTGTACGTGATGCATACAACCCGTTTCCAGCGGTTGGGGCGGGGATTTACACCACTAAGAGCCAAGCTGTGCCGACGG
GTTGTGTAGCTAAGTGTAAACCCGGTTTTGTTTTTAATCCCAATGAACCTTCAAAGTGCTCAATAGCCCCCTCAACAAAT
AATCATACTTGTCGAGGCCCCAAATTTATTTGTGAGCGAAGCCATGTCACTACAGGGGCCGCGTGTACAGTTGACGCGCC
TTATGCTGCCAATTTTATTGAAAATTTAAAAGATGGTTCTCGTTACGTGACAAGAGGCTGTGTTACACAGCAAGAGGCAT
TTGCAGCTGACAAGTACAATAAAGGCAATGACAATTGTAAAAATTATAATGTTGTAGTGCTACAAGACGCTCACTTTAAA
TGTACATTCGCTTGCTATGGTGATGCTTGTAATCTTGAATCTGTTCCAGATCATCCAGCAACATGGGCCGATGGTAAATC
GTCAACGGATTTACCTGATCAGTTTAATACTCCTTAA

Upstream 100 bases:

>100_bases
AAATTCCATGCTCATGCGATGGAATACGATGAAAATATGACCCCTCCGACTGAAATTGTTAATAAGCTACAAAGCATACT
GACTAAAGGAACACTCTAAT

Downstream 100 bases:

>100_bases
AGGCAGGTTTTAGTATGGCTGATAAAAAGGATAAACAATCATTTAACAATGGGACTCATCAGCCTAGCTTGAATGACATT
TTGAAAACGAGTAGCGACAC

Product: hypothetical protein

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNAQILRKNNNRGFNLLEIMVVVAIIGILAVVAVPLYKDYIIRAQVTEAFVFADAERIKVIEKRIESTNVDIATFSEPKV
HMTSLMWVPVINNQPVENSVIGYILPTMDLKGLGVRDTFALEYFYNGSWRCVNAANAIGRDAVSTNKALDDKYLPSSCRT
GAGLLAAHPKAPAGCPPGTQKAQVKDASGKQQQVCQRPKPQVQPQAQPQAQPQAQPQAQPQAQPQAQPQVKPQAVVKPPS
CPIGQDCSHKDPKCSVAGQEHIDQTSVPVRDAYNPFPAVGAGIYTTKSQAVPTGCVAKCKPGFVFNPNEPSKCSIAPSTN
NHTCRGPKFICERSHVTTGAACTVDAPYAANFIENLKDGSRYVTRGCVTQQEAFAADKYNKGNDNCKNYNVVVLQDAHFK
CTFACYGDACNLESVPDHPATWADGKSSTDLPDQFNTP

Sequences:

>Translated_438_residues
MNAQILRKNNNRGFNLLEIMVVVAIIGILAVVAVPLYKDYIIRAQVTEAFVFADAERIKVIEKRIESTNVDIATFSEPKV
HMTSLMWVPVINNQPVENSVIGYILPTMDLKGLGVRDTFALEYFYNGSWRCVNAANAIGRDAVSTNKALDDKYLPSSCRT
GAGLLAAHPKAPAGCPPGTQKAQVKDASGKQQQVCQRPKPQVQPQAQPQAQPQAQPQAQPQAQPQAQPQVKPQAVVKPPS
CPIGQDCSHKDPKCSVAGQEHIDQTSVPVRDAYNPFPAVGAGIYTTKSQAVPTGCVAKCKPGFVFNPNEPSKCSIAPSTN
NHTCRGPKFICERSHVTTGAACTVDAPYAANFIENLKDGSRYVTRGCVTQQEAFAADKYNKGNDNCKNYNVVVLQDAHFK
CTFACYGDACNLESVPDHPATWADGKSSTDLPDQFNTP
>Mature_438_residues
MNAQILRKNNNRGFNLLEIMVVVAIIGILAVVAVPLYKDYIIRAQVTEAFVFADAERIKVIEKRIESTNVDIATFSEPKV
HMTSLMWVPVINNQPVENSVIGYILPTMDLKGLGVRDTFALEYFYNGSWRCVNAANAIGRDAVSTNKALDDKYLPSSCRT
GAGLLAAHPKAPAGCPPGTQKAQVKDASGKQQQVCQRPKPQVQPQAQPQAQPQAQPQAQPQAQPQAQPQVKPQAVVKPPS
CPIGQDCSHKDPKCSVAGQEHIDQTSVPVRDAYNPFPAVGAGIYTTKSQAVPTGCVAKCKPGFVFNPNEPSKCSIAPSTN
NHTCRGPKFICERSHVTTGAACTVDAPYAANFIENLKDGSRYVTRGCVTQQEAFAADKYNKGNDNCKNYNVVVLQDAHFK
CTFACYGDACNLESVPDHPATWADGKSSTDLPDQFNTP

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 47432; Mature: 47432

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAQILRKNNNRGFNLLEIMVVVAIIGILAVVAVPLYKDYIIRAQVTEAFVFADAERIKV
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHCCHHHHHH
IEKRIESTNVDIATFSEPKVHMTSLMWVPVINNQPVENSVIGYILPTMDLKGLGVRDTFA
HHHHHHHCCCEEEECCCCCEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEE
LEYFYNGSWRCVNAANAIGRDAVSTNKALDDKYLPSSCRTGAGLLAAHPKAPAGCPPGTQ
EEEEECCCEEEEECHHHHCCCHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCC
KAQVKDASGKQQQVCQRPKPQVQPQAQPQAQPQAQPQAQPQAQPQAQPQVKPQAVVKPPS
CCEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
CPIGQDCSHKDPKCSVAGQEHIDQTSVPVRDAYNPFPAVGAGIYTTKSQAVPTGCVAKCK
CCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCCHHHCC
PGFVFNPNEPSKCSIAPSTNNHTCRGPKFICERSHVTTGAACTVDAPYAANFIENLKDGS
CCEEECCCCCCCEEECCCCCCCCCCCCHHHEECCCCCCCCEEEECCCHHHHHHHHHCCCC
RYVTRGCVTQQEAFAADKYNKGNDNCKNYNVVVLQDAHFKCTFACYGDACNLESVPDHPA
HHHHHHHCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCCCCCC
TWADGKSSTDLPDQFNTP
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNAQILRKNNNRGFNLLEIMVVVAIIGILAVVAVPLYKDYIIRAQVTEAFVFADAERIKV
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHCCHHHHHH
IEKRIESTNVDIATFSEPKVHMTSLMWVPVINNQPVENSVIGYILPTMDLKGLGVRDTFA
HHHHHHHCCCEEEECCCCCEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEE
LEYFYNGSWRCVNAANAIGRDAVSTNKALDDKYLPSSCRTGAGLLAAHPKAPAGCPPGTQ
EEEEECCCEEEEECHHHHCCCHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCC
KAQVKDASGKQQQVCQRPKPQVQPQAQPQAQPQAQPQAQPQAQPQAQPQVKPQAVVKPPS
CCEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
CPIGQDCSHKDPKCSVAGQEHIDQTSVPVRDAYNPFPAVGAGIYTTKSQAVPTGCVAKCK
CCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCCHHHCC
PGFVFNPNEPSKCSIAPSTNNHTCRGPKFICERSHVTTGAACTVDAPYAANFIENLKDGS
CCEEECCCCCCCEEECCCCCCCCCCCCHHHEECCCCCCCCEEEECCCHHHHHHHHHCCCC
RYVTRGCVTQQEAFAADKYNKGNDNCKNYNVVVLQDAHFKCTFACYGDACNLESVPDHPA
HHHHHHHCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCCCCCC
TWADGKSSTDLPDQFNTP
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3141743; 10710307; 8645220; 8993351; 9515697 [H]