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The map label for this gene is tadA [H]

Identifier: 160876335

GI number: 160876335

Start: 3797755

End: 3798192

Strand: Direct

Name: tadA [H]

Synonym: Sbal195_3229

Alternate gene names: 160876335

Gene position: 3797755-3798192 (Clockwise)

Preceding gene: 160876334

Following gene: 160876336

Centisome position: 71.02

GC content: 51.6

Gene sequence:

>438_bases
ATGGATGAATTTTTAGCGGCAGCCATTGAAGAAGCCAAACAGGGACTGGTCGAGGGCGGCATCCCTATTGGTTCGGTATT
AGTGATCGATGGCAAAATCGTCGGGCGCGGCCACAATAAACGGGTACAAAAAGGCAGTTCAGTACTGCATGCCGAAATGG
ATTGCCTCGAAAATGCCGGCCGATTTAGCGCCGCCGAGTACCAAAGAGCAACCTTGTATTCCACCCTATCGCCCTGTGAT
ATGTGCAGCGGCGCGGTATTACTTTATGGCATACCTAAAGTCATCGTCGGTGAAAACACCACTTTTCAAGGGCCAGAAGC
CTATGTCAAATCCCGCGGCGTCGATGTCACTGTGGTCGATAACGCCGAGTGCAAACAACTGATGCACGACTTTATCGCCA
GCCATCCCACACTCTGGAACGAAGATATCGGCGAGTAG

Upstream 100 bases:

>100_bases
GGGACTTATTGAAGCAACAAATCAAAACCATTTAGATTGTCTCCCAAACGAGTGCTATGCTGAGTTTAATATTCAGGGTT
CATATTTTAAGGATATCAAG

Downstream 100 bases:

>100_bases
TGGATCTTCACTCTTCTCAGTCACTTTCTATATTTCACTTGCTATCTTTTTTGTATTTCACTTTTTGTATTGGCTGTATT
TCATTGGGGGCTAGCGCCTG

Product: cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDEFLAAAIEEAKQGLVEGGIPIGSVLVIDGKIVGRGHNKRVQKGSSVLHAEMDCLENAGRFSAAEYQRATLYSTLSPCD
MCSGAVLLYGIPKVIVGENTTFQGPEAYVKSRGVDVTVVDNAECKQLMHDFIASHPTLWNEDIGE

Sequences:

>Translated_145_residues
MDEFLAAAIEEAKQGLVEGGIPIGSVLVIDGKIVGRGHNKRVQKGSSVLHAEMDCLENAGRFSAAEYQRATLYSTLSPCD
MCSGAVLLYGIPKVIVGENTTFQGPEAYVKSRGVDVTVVDNAECKQLMHDFIASHPTLWNEDIGE
>Mature_145_residues
MDEFLAAAIEEAKQGLVEGGIPIGSVLVIDGKIVGRGHNKRVQKGSSVLHAEMDCLENAGRFSAAEYQRATLYSTLSPCD
MCSGAVLLYGIPKVIVGENTTFQGPEAYVKSRGVDVTVVDNAECKQLMHDFIASHPTLWNEDIGE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=111, Percent_Identity=30.6306306306306, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17541138, Length=143, Percent_Identity=34.2657342657343, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=37.1134020618557, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325319, Length=141, Percent_Identity=53.1914893617021, Blast_Score=160, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15598; Mature: 15598

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEFLAAAIEEAKQGLVEGGIPIGSVLVIDGKIVGRGHNKRVQKGSSVLHAEMDCLENAG
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCHHHCCCHHHHHHHHHHHCCC
RFSAAEYQRATLYSTLSPCDMCSGAVLLYGIPKVIVGENTTFQGPEAYVKSRGVDVTVVD
CCCHHHHHHHHHHHHCCCHHHHCCCEEEECCCEEEECCCCCCCCHHHHHHHCCCEEEEEC
NAECKQLMHDFIASHPTLWNEDIGE
CHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDEFLAAAIEEAKQGLVEGGIPIGSVLVIDGKIVGRGHNKRVQKGSSVLHAEMDCLENAG
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCHHHCCCHHHHHHHHHHHCCC
RFSAAEYQRATLYSTLSPCDMCSGAVLLYGIPKVIVGENTTFQGPEAYVKSRGVDVTVVD
CCCHHHHHHHHHHHHCCCHHHHCCCEEEECCCEEEECCCCCCCCHHHHHHHCCCEEEEEC
NAECKQLMHDFIASHPTLWNEDIGE
CHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]