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The map label for this gene is xapR [H]

Identifier: 160876334

GI number: 160876334

Start: 3796772

End: 3797689

Strand: Direct

Name: xapR [H]

Synonym: Sbal195_3228

Alternate gene names: 160876334

Gene position: 3796772-3797689 (Clockwise)

Preceding gene: 160876332

Following gene: 160876335

Centisome position: 71.0

GC content: 47.17

Gene sequence:

>918_bases
ATGAGCAAGATAAACGCACCAGAACTCGTCACCTTGAAGATGCTGCGGTATTTTCATCGGGTTGCGGAAGTGAAAAACTT
TACCGCTGCTGCCGAGCAACTGCATCTATCGAAATCTCCGCTGAGCGCACAAATCAAAGAGTTGGAATCGCTCCTTGGTG
TTGAGCTGTTCACTCGCAGCACTCGGCAAGTAGAGCTCACACCCTATGGCCAATTGTTAAGAGAAAAGTGCGAGCAAATA
TTCGAGCTGGTGAATACCTCATTGGAGCAAGTGGCTCAGCTTGGACGACTCGATAGAAACCATATTCGGATTGGCATCAT
GAGCTCGCTGTTTTGGATGGGATTTGGGGACATACTGAAAAGCTTTCGCAAGCAATGCCCTGAAAATAAGCTGATCTTTC
AAGAGTTATCACCTGAAACTCAAAAAGTCGCCTTAGCGCATCAAGAAATCGATTTTGGCCTAGTGCGCTACGCCGACACC
TTAAATCTGCCGCACCTCATCGCCGAAACCATCACCAGCGAACCTATGGTGTTAGCGCTGGCAAATAAACATCCCTTAGC
CAGACGTAAAAGCATCGACTTGAGTGAACTCAAAGATGAGCCCTTTACCTTACTCAGCCGTGCCAACTCCGCCTCTAGCG
ATTTGATTATCGCCAACTGTCAGGCCGAAGGATTTATACCACAGCTGATACAGGAAATGGTCGAGCCCAATAGCTTGATG
GCGATCATCGCTGGCGATAACAGGGTATCCATAGTGCCGCAAAGTTATGCATCACAGCCTTGGCCTAGGGTAAAGTTTAT
TAAATTAAAACAAACAATCACCGCCGATATCTGCCTGATTTATCGGCCAGAAATGGCTTCGCTGCCGATTCTCGATAGCC
TGAGGGACTTATTGAAGCAACAAATCAAAACCATTTAG

Upstream 100 bases:

>100_bases
ACGCCCTCAGTATAAGCGGGTTTAGGGTTGCAAATAATCGCGATTAATCGCACTATTGTGCTGATAAAAAGGATAATAAC
TAAAAAGCAGTGAGCCTGAG

Downstream 100 bases:

>100_bases
ATTGTCTCCCAAACGAGTGCTATGCTGAGTTTAATATTCAGGGTTCATATTTTAAGGATATCAAGATGGATGAATTTTTA
GCGGCAGCCATTGAAGAAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Xanthosine operon regulatory protein [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRSTRQVELTPYGQLLREKCEQI
FELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILKSFRKQCPENKLIFQELSPETQKVALAHQEIDFGLVRYADT
LNLPHLIAETITSEPMVLALANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIANCQAEGFIPQLIQEMVEPNSLM
AIIAGDNRVSIVPQSYASQPWPRVKFIKLKQTITADICLIYRPEMASLPILDSLRDLLKQQIKTI

Sequences:

>Translated_305_residues
MSKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRSTRQVELTPYGQLLREKCEQI
FELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILKSFRKQCPENKLIFQELSPETQKVALAHQEIDFGLVRYADT
LNLPHLIAETITSEPMVLALANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIANCQAEGFIPQLIQEMVEPNSLM
AIIAGDNRVSIVPQSYASQPWPRVKFIKLKQTITADICLIYRPEMASLPILDSLRDLLKQQIKTI
>Mature_304_residues
SKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRSTRQVELTPYGQLLREKCEQIF
ELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILKSFRKQCPENKLIFQELSPETQKVALAHQEIDFGLVRYADTL
NLPHLIAETITSEPMVLALANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIANCQAEGFIPQLIQEMVEPNSLMA
IIAGDNRVSIVPQSYASQPWPRVKFIKLKQTITADICLIYRPEMASLPILDSLRDLLKQQIKTI

Specific function: Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=270, Percent_Identity=32.5925925925926, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI157672245, Length=250, Percent_Identity=32.4, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=31.2, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788887, Length=226, Percent_Identity=30.5309734513274, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=27.5720164609054, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=23.5714285714286, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081904, Length=195, Percent_Identity=26.1538461538462, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790262, Length=192, Percent_Identity=28.125, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI145693105, Length=211, Percent_Identity=23.696682464455, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34549; Mature: 34418

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
TRQVELTPYGQLLREKCEQIFELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILK
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
SFRKQCPENKLIFQELSPETQKVALAHQEIDFGLVRYADTLNLPHLIAETITSEPMVLAL
HHHHHCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEE
ANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIANCQAEGFIPQLIQEMVEPNSLM
CCCCCCHHHCCCCHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEE
AIIAGDNRVSIVPQSYASQPWPRVKFIKLKQTITADICLIYRPEMASLPILDSLRDLLKQ
EEEECCCEEEECCHHHCCCCCCCEEEEEHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHH
QIKTI
HHHCC
>Mature Secondary Structure 
SKINAPELVTLKMLRYFHRVAEVKNFTAAAEQLHLSKSPLSAQIKELESLLGVELFTRS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
TRQVELTPYGQLLREKCEQIFELVNTSLEQVAQLGRLDRNHIRIGIMSSLFWMGFGDILK
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
SFRKQCPENKLIFQELSPETQKVALAHQEIDFGLVRYADTLNLPHLIAETITSEPMVLAL
HHHHHCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEE
ANKHPLARRKSIDLSELKDEPFTLLSRANSASSDLIIANCQAEGFIPQLIQEMVEPNSLM
CCCCCCHHHCCCCHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEE
AIIAGDNRVSIVPQSYASQPWPRVKFIKLKQTITADICLIYRPEMASLPILDSLRDLLKQ
EEEECCCEEEECCHHHCCCCCCCEEEEEHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHH
QIKTI
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2201776; 9205837; 9278503; 7559336 [H]