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The map label for this gene is mlrA [H]

Identifier: 160876318

GI number: 160876318

Start: 3780941

End: 3781948

Strand: Reverse

Name: mlrA [H]

Synonym: Sbal195_3212

Alternate gene names: 160876318

Gene position: 3781948-3780941 (Counterclockwise)

Preceding gene: 160876319

Following gene: 160876317

Centisome position: 70.73

GC content: 48.31

Gene sequence:

>1008_bases
ATGACCAACGATGAGCCCAATGATGGAGTATTACTCCCCATTGGTGAAGTGTCGGCCTTAACCGGCGTGAATGCCGTGAC
CTTAAGGGCATGGCAGCGCCGTTTTGGTTTAGTGATCCCTGCGCGCACGCCCAAGGGACACAGATTATATACGAGTGAAA
ATATTCAAGAAATCCATGAGATTAATGCATGGTTAGCTAAAGGTGTTGCGATCAGTAAGGTTAAACCTTTGCTGATGAGT
GCCGCCAAATTATCAAGTGAAATGATTGAATCCCAAGTTGTCGATCTGTGGGGTGAGCAAATTACTGCGCTGAATGCAGC
ATTGTTCGACTTCAATCAGCATAAATTGCAGCAGATATTAGACGATGCATTTGGCTTATATCCGTTTCAATTAGTGAAAG
AAAAGTTACTGCAACCTTGGCTTAATCAACTCGAAGACTTAGTGGATGAGCGGCTCGATGCCGAGTTAATTCTCGCTTGG
TTAAAAAGCGAATTACTCAGCCGAGTGGGTGGGCGTTATGCATTTACCGGACAGGCCATTGCGGCGCGAATGGCTGTGGT
GCAGTTATCCCGCGGCGCGGCCACGCCGCCTAATTCTGCCCGTACTAAAAGCTTGTTTTCTCTGCTCCTATCGCTCGAGT
TAGCGTCGCTTCGAGTATCGGTAATCGACCTTGGCGAGCAGGCTATAGACACTTTGCCACTGCTGCAGGGCAGGCTTAAC
GTCGATGCACTTTTGCTTATGCCTGATCCAAATCATTCGGGGTCTGAGCAGACTGAAATGCTCACTGTATTGGCACAAAT
GAGTTTCCCCTGTCGATTTGTTGGCCCCTTTGCGCCGACCTTGACTTCCTTATCGGCTTTCTGGGCGCCTTCGATGACAG
ACTTGATTGGACAAATACCGTCTCGCTCCGTGGGTAAGGTCAACAGAAGTCACAAAGGCAAAGGGAAAAGTATTGGCGTG
AGTCAAAGCGAGCAGGGCAATAGTGGAGAAAACAATGACATCAGTTAA

Upstream 100 bases:

>100_bases
GCTGCGCTATGCCTACTAGCATTGGCTTTGTTGTACTGAGTGGTTTTTAGCTTTGAATTTAGTGAGTTATTACTGATATA
TGAAACAAGATACCCAGTCC

Downstream 100 bases:

>100_bases
CGATTCAATGCCAGTAGATTCAATGCGAATAGAAGTGCAGGGCAATAATGCACTGATGTGGTTTCGCCAAGATTTACGCC
TTGCCGATAATCAGGCGCTA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: MerR-like regulator A [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSENIQEIHEINAWLAKGVAISKVKPLLMS
AAKLSSEMIESQVVDLWGEQITALNAALFDFNQHKLQQILDDAFGLYPFQLVKEKLLQPWLNQLEDLVDERLDAELILAW
LKSELLSRVGGRYAFTGQAIAARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIDTLPLLQGRLN
VDALLLMPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLTSLSAFWAPSMTDLIGQIPSRSVGKVNRSHKGKGKSIGV
SQSEQGNSGENNDIS

Sequences:

>Translated_335_residues
MTNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSENIQEIHEINAWLAKGVAISKVKPLLMS
AAKLSSEMIESQVVDLWGEQITALNAALFDFNQHKLQQILDDAFGLYPFQLVKEKLLQPWLNQLEDLVDERLDAELILAW
LKSELLSRVGGRYAFTGQAIAARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIDTLPLLQGRLN
VDALLLMPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLTSLSAFWAPSMTDLIGQIPSRSVGKVNRSHKGKGKSIGV
SQSEQGNSGENNDIS
>Mature_334_residues
TNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSENIQEIHEINAWLAKGVAISKVKPLLMSA
AKLSSEMIESQVVDLWGEQITALNAALFDFNQHKLQQILDDAFGLYPFQLVKEKLLQPWLNQLEDLVDERLDAELILAWL
KSELLSRVGGRYAFTGQAIAARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIDTLPLLQGRLNV
DALLLMPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLTSLSAFWAPSMTDLIGQIPSRSVGKVNRSHKGKGKSIGVS
QSEQGNSGENNDIS

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF) [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788448, Length=129, Percent_Identity=41.0852713178295, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787409, Length=70, Percent_Identity=51.4285714285714, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 36576; Mature: 36444

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSENIQEIHE
CCCCCCCCCEEEECCCHHHHHCCHHHHHHHHHHHHCEEEECCCCCCCEEECHHHHHHHHH
INAWLAKGVAISKVKPLLMSAAKLSSEMIESQVVDLWGEQITALNAALFDFNQHKLQQIL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DDAFGLYPFQLVKEKLLQPWLNQLEDLVDERLDAELILAWLKSELLSRVGGRYAFTGQAI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHH
AARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIDTLPLLQGRLN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCC
VDALLLMPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLTSLSAFWAPSMTDLIGQIP
CCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHCCCHHHHHHCCC
SRSVGKVNRSHKGKGKSIGVSQSEQGNSGENNDIS
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSENIQEIHE
CCCCCCCCEEEECCCHHHHHCCHHHHHHHHHHHHCEEEECCCCCCCEEECHHHHHHHHH
INAWLAKGVAISKVKPLLMSAAKLSSEMIESQVVDLWGEQITALNAALFDFNQHKLQQIL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DDAFGLYPFQLVKEKLLQPWLNQLEDLVDERLDAELILAWLKSELLSRVGGRYAFTGQAI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHH
AARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIDTLPLLQGRLN
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCC
VDALLLMPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLTSLSAFWAPSMTDLIGQIP
CCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHCCCHHHHHHCCC
SRSVGKVNRSHKGKGKSIGVSQSEQGNSGENNDIS
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 9278503 [H]