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The map label for this gene is cirA [H]

Identifier: 160875643

GI number: 160875643

Start: 2991127

End: 2993169

Strand: Direct

Name: cirA [H]

Synonym: Sbal195_2531

Alternate gene names: 160875643

Gene position: 2991127-2993169 (Clockwise)

Preceding gene: 160875641

Following gene: 160875645

Centisome position: 55.94

GC content: 49.78

Gene sequence:

>2043_bases
ATGCACTATTTAAGAATAATTATCATTCGCCGAAATTATCCAAGGAAGAATGATATGTCCCGCTTTATCCGCCGTACTCG
CAAAACAAGTCATACATCCGGTGCAACTCTGTCTCCTAAACTGAGCCTGCTATCGCGCGCCATTGGCTTAAGCCTGTTGT
TACCCGCTGCATGGGCAACTGCCGCAGCTCCCCAAGATGCCACGCCAGAAATGGAACGTATGGTGATCACAGCTACGCAA
ACTCAGCATTCTGAACTGTCGGCGCCCGCTTCTGTGTCTGTGATAAATCGCAGTGAACTCGAAGCGCTAGTCATAGACGA
TCTGGCCAGTGCAGTGCGTTATTTACAGGGCGTGAATATCAGTGAAGGCACGCCCTATGGTCGCAATGAAATTAGTCTGC
GCGGACTGGATTCTGACTACACGCTGATCTTAATCAACGGTCGCCGAGTCAACTCCCGCGAAGCACTAACCTCCGGTTAT
GGCAACGATTTTGACTTATCATCCATTCCCATGTCTGCCATTGAACGTATCGAAGTCGTGCGCGGGCCTATGTCATCCCT
GTATGGCTCCGAAGCTTTAGGTGGCGTGGTTAACGTGATTTTGCGCCAACCCACTGACGACTGGCAGACCAGTGTCGGCG
TACAATACGATACGCCCACCAGCGGCAAAGGCGGCAACAGCACTAAGTACAACTTCTACACCAGCGGCGCGCTGATCAAA
GATAAATTACTGGCAAACTTAATCGTCGACAGCAATCAACGCGATGCATGGCGTTCAGACTTAAAACCCACCATTGATGC
GCTAGAAGACAGAGATGAAATCAGCGCCCTCGCTAACCTGCAATGGTTGATTGATAGCCAGCAAGATCTGCAATTTGATT
TAAGTTACGCCAACGACGAACGCGAATCGGATTGGAATAACTACGGCACAATTCTCACCAATAACCAACGAGCCGAGCGG
ATAAGCTCAGGTCTAACCCACAATGGCCACTGGAACTGGGGCGATACTCGCCTGCGCTATTACTATGAAAATGTTGAGGT
AACTGACGACTCGGCGCTGATCGCCGAGATTGGGCATATCACCCAAACCAACCACAATCTCGACGGCCAAACCACAGTAC
TACTTGGGGATCACATGTTAACCAGCGGCGCGGAATACCGTTGGACTCAGCTTGAAAACAGCCGCAATATTTTGGGTGAT
GGCACCTTAGACGACAGCCAGTCGGCCTTGTATCTGCAAGATGAATTTAGCTTAGGCGAACTCAATATCACCTTAGGGGG
GCGCGTCGATCACCACGATGTGTACGGCACCGAATTTAGCCCACGCGTGTATTTGGTGTATAACTTAAGCTCTGAATGGG
TGATCAAAGGTGGCGGTGGCAAGGCATTTAAAGCGCCAAATATGTCGCAATCCCAAGCCGATTATATTATCCCCGCTTGT
CGCGGCGCCTGCACCGTTGCGGGGAATCCCGATCTACAGCCCGAAACCTCAGTGAACTACGAGTTATCGACCCAATATCA
AACCACGGATTTTGGTGGCTCAATCACCTACTTCCACAACGATGTGGAAAATAAAATCATCACAGAAACCTGGGATAGAA
CGCCCGGCGCAGTGTTGACTTATCAAAACGTGAACGAAGCCAAGATCACAGGTTGGGAACTGCAGGCTTGGTACGATGTA
ACCGACACGGTCAGCTTTAGCGGTAATTACAGTAAAACCGATGCCGAAGATAAGCAAAATGGCGCGCCTTTTACCCTAAC
GCCGGATGACAGCTACAACCTGAAACTGCAATGGCAGGCATTGGATGGCTTATCCACCTTTATCGCCTACCACTATACTG
GCGATCAGTATTTGCGCACCAATGTAAAATCGACGGGTTATGGTTCACTCGACCTAGGCGCGAATTACCAAATTAATCCT
ATGTTCAGAGTCAAACTCGGCGTCACTAACCTAACGGATGCTGAGCGCGACCAAGTGGCTACCGATCTTGATTACATTCA
AAAGAGCCGCAGTATTTATGCGGGCGTGACGGCAAGTTTCTAA

Upstream 100 bases:

>100_bases
GGTGAAAGCTGCGATCCACAACTGACATACCCACCATCATACTGTTATTAAACAGTAAAATTTACATGGCATTTACACAA
AAGCGGGATCTGCACTCTTG

Downstream 100 bases:

>100_bases
TTAGCAATCTGCCACACACATGGATTTCTTTAGCTGAAAACGGGCTTGCGAAACTATCGCCAGCCCGTTTTTTATGAATT
CGTTGAATACTTTCGAACTT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MHYLRIIIIRRNYPRKNDMSRFIRRTRKTSHTSGATLSPKLSLLSRAIGLSLLLPAAWATAAAPQDATPEMERMVITATQ
TQHSELSAPASVSVINRSELEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSGY
GNDFDLSSIPMSAIERIEVVRGPMSSLYGSEALGGVVNVILRQPTDDWQTSVGVQYDTPTSGKGGNSTKYNFYTSGALIK
DKLLANLIVDSNQRDAWRSDLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDERESDWNNYGTILTNNQRAER
ISSGLTHNGHWNWGDTRLRYYYENVEVTDDSALIAEIGHITQTNHNLDGQTTVLLGDHMLTSGAEYRWTQLENSRNILGD
GTLDDSQSALYLQDEFSLGELNITLGGRVDHHDVYGTEFSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPAC
RGACTVAGNPDLQPETSVNYELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDV
TDTVSFSGNYSKTDAEDKQNGAPFTLTPDDSYNLKLQWQALDGLSTFIAYHYTGDQYLRTNVKSTGYGSLDLGANYQINP
MFRVKLGVTNLTDAERDQVATDLDYIQKSRSIYAGVTASF

Sequences:

>Translated_680_residues
MHYLRIIIIRRNYPRKNDMSRFIRRTRKTSHTSGATLSPKLSLLSRAIGLSLLLPAAWATAAAPQDATPEMERMVITATQ
TQHSELSAPASVSVINRSELEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSGY
GNDFDLSSIPMSAIERIEVVRGPMSSLYGSEALGGVVNVILRQPTDDWQTSVGVQYDTPTSGKGGNSTKYNFYTSGALIK
DKLLANLIVDSNQRDAWRSDLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDERESDWNNYGTILTNNQRAER
ISSGLTHNGHWNWGDTRLRYYYENVEVTDDSALIAEIGHITQTNHNLDGQTTVLLGDHMLTSGAEYRWTQLENSRNILGD
GTLDDSQSALYLQDEFSLGELNITLGGRVDHHDVYGTEFSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPAC
RGACTVAGNPDLQPETSVNYELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDV
TDTVSFSGNYSKTDAEDKQNGAPFTLTPDDSYNLKLQWQALDGLSTFIAYHYTGDQYLRTNVKSTGYGSLDLGANYQINP
MFRVKLGVTNLTDAERDQVATDLDYIQKSRSIYAGVTASF
>Mature_680_residues
MHYLRIIIIRRNYPRKNDMSRFIRRTRKTSHTSGATLSPKLSLLSRAIGLSLLLPAAWATAAAPQDATPEMERMVITATQ
TQHSELSAPASVSVINRSELEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSGY
GNDFDLSSIPMSAIERIEVVRGPMSSLYGSEALGGVVNVILRQPTDDWQTSVGVQYDTPTSGKGGNSTKYNFYTSGALIK
DKLLANLIVDSNQRDAWRSDLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDERESDWNNYGTILTNNQRAER
ISSGLTHNGHWNWGDTRLRYYYENVEVTDDSALIAEIGHITQTNHNLDGQTTVLLGDHMLTSGAEYRWTQLENSRNILGD
GTLDDSQSALYLQDEFSLGELNITLGGRVDHHDVYGTEFSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPAC
RGACTVAGNPDLQPETSVNYELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDV
TDTVSFSGNYSKTDAEDKQNGAPFTLTPDDSYNLKLQWQALDGLSTFIAYHYTGDQYLRTNVKSTGYGSLDLGANYQINP
MFRVKLGVTNLTDAERDQVATDLDYIQKSRSIYAGVTASF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=678, Percent_Identity=34.8082595870207, Blast_Score=326, Evalue=3e-90,
Organism=Escherichia coli, GI1786798, Length=690, Percent_Identity=26.8115942028986, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1790405, Length=643, Percent_Identity=23.3281493001555, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75678; Mature: 75678

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYLRIIIIRRNYPRKNDMSRFIRRTRKTSHTSGATLSPKLSLLSRAIGLSLLLPAAWAT
CCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAAPQDATPEMERMVITATQTQHSELSAPASVSVINRSELEALVIDDLASAVRYLQGVNI
CCCCCCCCCCHHEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCC
SEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSGYGNDFDLSSIPMSAIERIEVV
CCCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHH
RGPMSSLYGSEALGGVVNVILRQPTDDWQTSVGVQYDTPTSGKGGNSTKYNFYTSGALIK
HCCHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCEEECCCCCCCCCCCCEEEEEECCCHHH
DKLLANLIVDSNQRDAWRSDLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDE
HHHHHHHHCCCCCCHHHHHCCCHHHHHHCCHHHHHHHHCEEEEECCCCCCEEEEEECCCC
RESDWNNYGTILTNNQRAERISSGLTHNGHWNWGDTRLRYYYENVEVTDDSALIAEIGHI
CCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCCEEEEEEECEEECCCCHHHHHHCCC
TQTNHNLDGQTTVLLGDHMLTSGAEYRWTQLENSRNILGDGTLDDSQSALYLQDEFSLGE
CCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEECCCCCCCCCCEEEEEECCCEEE
LNITLGGRVDHHDVYGTEFSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPAC
EEEEECCEECCCCCCCCCCCCEEEEEEECCCCEEEECCCCCEEECCCCCCCCCCEEEECC
RGACTVAGNPDLQPETSVNYELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLT
CCEEEECCCCCCCCCCCCCEEEECEEEECCCCCEEEEEECCCCCCEEEHHCCCCCCEEEE
YQNVNEAKITGWELQAWYDVTDTVSFSGNYSKTDAEDKQNGAPFTLTPDDSYNLKLQWQA
ECCCCCCEEEEEEEEEEEEECEEEEECCCCCCCCCCHHCCCCCEEECCCCCCEEEEEEEE
LDGLSTFIAYHYTGDQYLRTNVKSTGYGSLDLGANYQINPMFRVKLGVTNLTDAERDQVA
CCCCEEEEEEEECCCHHEEECCCCCCCCCEECCCCEEECEEEEEEECCCCCCCCHHHHHH
TDLDYIQKSRSIYAGVTASF
HHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure
MHYLRIIIIRRNYPRKNDMSRFIRRTRKTSHTSGATLSPKLSLLSRAIGLSLLLPAAWAT
CCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAAPQDATPEMERMVITATQTQHSELSAPASVSVINRSELEALVIDDLASAVRYLQGVNI
CCCCCCCCCCHHEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCC
SEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSGYGNDFDLSSIPMSAIERIEVV
CCCCCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHH
RGPMSSLYGSEALGGVVNVILRQPTDDWQTSVGVQYDTPTSGKGGNSTKYNFYTSGALIK
HCCHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCEEECCCCCCCCCCCCEEEEEECCCHHH
DKLLANLIVDSNQRDAWRSDLKPTIDALEDRDEISALANLQWLIDSQQDLQFDLSYANDE
HHHHHHHHCCCCCCHHHHHCCCHHHHHHCCHHHHHHHHCEEEEECCCCCCEEEEEECCCC
RESDWNNYGTILTNNQRAERISSGLTHNGHWNWGDTRLRYYYENVEVTDDSALIAEIGHI
CCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCCEEEEEEECEEECCCCHHHHHHCCC
TQTNHNLDGQTTVLLGDHMLTSGAEYRWTQLENSRNILGDGTLDDSQSALYLQDEFSLGE
CCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEECCCCCCCCCCEEEEEECCCEEE
LNITLGGRVDHHDVYGTEFSPRVYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIIPAC
EEEEECCEECCCCCCCCCCCCEEEEEEECCCCEEEECCCCCEEECCCCCCCCCCEEEECC
RGACTVAGNPDLQPETSVNYELSTQYQTTDFGGSITYFHNDVENKIITETWDRTPGAVLT
CCEEEECCCCCCCCCCCCCEEEECEEEECCCCCEEEEEECCCCCCEEEHHCCCCCCEEEE
YQNVNEAKITGWELQAWYDVTDTVSFSGNYSKTDAEDKQNGAPFTLTPDDSYNLKLQWQA
ECCCCCCEEEEEEEEEEEEECEEEEECCCCCCCCCCHHCCCCCEEECCCCCCEEEEEEEE
LDGLSTFIAYHYTGDQYLRTNVKSTGYGSLDLGANYQINPMFRVKLGVTNLTDAERDQVA
CCCCEEEEEEEECCCHHEEECCCCCCCCCEECCCCEEECEEEEEEECCCCCCCCHHHHHH
TDLDYIQKSRSIYAGVTASF
HHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]