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The map label for this gene is ydhC [H]

Identifier: 160875423

GI number: 160875423

Start: 2731353

End: 2732624

Strand: Reverse

Name: ydhC [H]

Synonym: Sbal195_2311

Alternate gene names: 160875423

Gene position: 2732624-2731353 (Counterclockwise)

Preceding gene: 160875430

Following gene: 160875420

Centisome position: 51.1

GC content: 46.54

Gene sequence:

>1272_bases
ATGAAAACGTCTAGTAACACCTTTGTAAACATAAAGTTCTTTATGTTTCTATTCTATTTAGCCATGTTGAGCATGCTCGG
CTTTATTGCCACTGACATGTATTTGCCTGCTTTCAAAGCAATTGAAGGCTCACTTAACAGTACCCCATCACAGGTGGCGA
TGTCGCTGACCTGTTTCCTGGCGGGTCTTGCCTTAGGTCAGCTACTTTATGGCCCCTTAGTCAATAAAATCGGCAAACGT
TGGGCACTGATTTTTGGCCTAGTGCTATTTGCCGTTGCCAGCGTGTTTATTGCCAACAGTGATTCTATCCTAATGCTCAA
TACCGCGCGCTTCTTCCAAGCGATTGGCGCCTGTAGTGCAGGGGTTATTTGGCAAGCGATTGTGGTTGAGCAATATGATG
CCGATAAAGCACAGGGTATTTTCAGTAACATTATGCCACTGGTCGCATTATCGCCTGCATTAGCGCCGATCCTTGGCGCT
TACATTCTGAACGAATTAGGCTGGCGTGCAATCTTTATCTCTTTGTGTGTTATCGCTTTTCTACTGATATTGATGACATT
GTACTTTGTGCCAGGCAAGCGTCAGCATACACACAGTGAACATGCTGCGGTATCTTATGGGCAAATTTTGAAAAACACCC
GCTATTTAGGCAACGTCGTGATCTTCGGCGCCTGTTCCGGTGCTTTCTTTGCTTATCTAACCGTATGGCCGATTGTGATG
GAAATGCACGGTTATCTGCCAACTGAAATCGGCCTTAGCTTTATCCCGCAAACCATCATGTTTATTGTCGGTGGTTATGC
GAGTAAGTTACTGATAAAACGCATTGGCGGGCATCAAACACTGAATATCTTGTTGTCGATTTTCGCAGCCTGCGTTATTT
CGATCATCATGTTCACGCTGATTTTCCCAGCAAGCACGATTTTCCCACTGCTTATTTCGTTCTCGATTTTGGCCGCAGCT
AATGGCGCCATTTACCCGATAGTCGTGAACAGCGCGCTACAGCAGTTTAGTCAGAATGCCGCTAAGGCCGCAGGATTACA
GAACTTTTTGCAGATCAGCATTGCCTTCGGTGCATCTAGCTTAGTTGCTATGTGGGCAAGCCTAGGTGAAGTAGCGATCG
GTTGGGGCATCCTATGTTGCGCTATCTTAGTTGTGGTCGGCTATGTGCTGAAGAGCCAACAAGGGTGGGACGATTTTGCC
AAACATTTCACTAAGCCAGATCCCGCACGTGTTGGCATAGTGGCCGATGTGAAGCAAAATCCAGCGGATTGA

Upstream 100 bases:

>100_bases
CAATGAAAATAATTGATAGCACAAGTCAAAAATAAACGTTTCCAATAAATTTAACAAGTCATTAGACTGCACGCTTTAGT
CAATCCGACCCGATTATTTT

Downstream 100 bases:

>100_bases
GTGTAATAGCAACAATCGGCGCATAATTGAGAGTTAGTGCTTTACAGTCAACACACTTACTTATATTATGCGCCTCGTTC
GGAGGGGTGGCAGAGTGGTT

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFLAGLALGQLLYGPLVNKIGKR
WALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSAGVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGA
YILNELGWRAIFISLCVIAFLLILMTLYFVPGKRQHTHSEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTLIFPASTIFPLLISFSILAAA
NGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASSLVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWDDFA
KHFTKPDPARVGIVADVKQNPAD

Sequences:

>Translated_423_residues
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFLAGLALGQLLYGPLVNKIGKR
WALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSAGVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGA
YILNELGWRAIFISLCVIAFLLILMTLYFVPGKRQHTHSEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTLIFPASTIFPLLISFSILAAA
NGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASSLVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWDDFA
KHFTKPDPARVGIVADVKQNPAD
>Mature_423_residues
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFLAGLALGQLLYGPLVNKIGKR
WALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSAGVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGA
YILNELGWRAIFISLCVIAFLLILMTLYFVPGKRQHTHSEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTLIFPASTIFPLLISFSILAAA
NGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASSLVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWDDFA
KHFTKPDPARVGIVADVKQNPAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=381, Percent_Identity=43.0446194225722, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI1788509, Length=269, Percent_Identity=28.2527881040892, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1790146, Length=240, Percent_Identity=25, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787065, Length=289, Percent_Identity=24.9134948096886, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790794, Length=227, Percent_Identity=22.9074889867841, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082312, Length=363, Percent_Identity=22.038567493113, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45739; Mature: 45739

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFL
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AGLALGQLLYGPLVNKIGKRWALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCHH
GVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGAYILNELGWRAIFISLCVIAF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLILMTLYFVPGKRQHTHSEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHCCEEEEECCHHHHHHHHHHHHHHH
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IFPASTIFPLLISFSILAAANGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASS
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
LVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWDDFAKHFTKPDPARVGIVADVKQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEEEECCCC
PAD
CCC
>Mature Secondary Structure
MKTSSNTFVNIKFFMFLFYLAMLSMLGFIATDMYLPAFKAIEGSLNSTPSQVAMSLTCFL
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AGLALGQLLYGPLVNKIGKRWALIFGLVLFAVASVFIANSDSILMLNTARFFQAIGACSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCHH
GVIWQAIVVEQYDADKAQGIFSNIMPLVALSPALAPILGAYILNELGWRAIFISLCVIAF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLILMTLYFVPGKRQHTHSEHAAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHCCEEEEECCHHHHHHHHHHHHHHH
EMHGYLPTEIGLSFIPQTIMFIVGGYASKLLIKRIGGHQTLNILLSIFAACVISIIMFTL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IFPASTIFPLLISFSILAAANGAIYPIVVNSALQQFSQNAAKAAGLQNFLQISIAFGASS
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
LVAMWASLGEVAIGWGILCCAILVVVGYVLKSQQGWDDFAKHFTKPDPARVGIVADVKQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEEEECCCC
PAD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]