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The map label for this gene is umuD [H]

Identifier: 160875103

GI number: 160875103

Start: 2374422

End: 2374697

Strand: Direct

Name: umuD [H]

Synonym: Sbal195_1988

Alternate gene names: 160875103

Gene position: 2374422-2374697 (Clockwise)

Preceding gene: 160875102

Following gene: 160875104

Centisome position: 44.4

GC content: 42.39

Gene sequence:

>276_bases
ATGATTATGCATTATCTTCTTTTTATTCCTGCCTCTAAGTATGCAAGGAATAGTGGTTTTGAAAGTCTCGCAGCAGAATA
CCAGCAGTTGAGCTTAAGTCTTGATGAGCTACTTGTGCAGCATCCTAGCTCCACGTATGTGGAGATTACCGAGGGGGATT
TGATGCTGGGTGAGGGGATTTATGATGGTGATTTGCTGATTGTAGATCGGCATATTACTGCACAGCATGGAGCTGACTTT
ATTTTGTTAATTGTGAACAGCCGCCTGTTGATTTGA

Upstream 100 bases:

>100_bases
AGCTTTATTGCAAAATCACTTAACTGATAACTAAATCATTCAAAATTTGCTAACCGGGAAGTACTGCATGCAATGACGGT
GATTTTACGCAGTACTCGAT

Downstream 100 bases:

>100_bases
AAATTCTCAATTAAAAGTGCCCAGTTTGGATTGACCAGTACATAATCAGTCAAATGATTGATGTGCATACTAAAGTAAAA
GCAGCTAGGCTTTACATCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MIMHYLLFIPASKYARNSGFESLAAEYQQLSLSLDELLVQHPSSTYVEITEGDLMLGEGIYDGDLLIVDRHITAQHGADF
ILLIVNSRLLI

Sequences:

>Translated_91_residues
MIMHYLLFIPASKYARNSGFESLAAEYQQLSLSLDELLVQHPSSTYVEITEGDLMLGEGIYDGDLLIVDRHITAQHGADF
ILLIVNSRLLI
>Mature_91_residues
MIMHYLLFIPASKYARNSGFESLAAEYQQLSLSLDELLVQHPSSTYVEITEGDLMLGEGIYDGDLLIVDRHITAQHGADF
ILLIVNSRLLI

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=75, Percent_Identity=46.6666666666667, Blast_Score=69, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 10209; Mature: 10209

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMHYLLFIPASKYARNSGFESLAAEYQQLSLSLDELLVQHPSSTYVEITEGDLMLGEGI
CEEEEEEEECCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCEEECCCC
YDGDLLIVDRHITAQHGADFILLIVNSRLLI
CCCCEEEEECCCCCCCCCCEEEEEECCEECC
>Mature Secondary Structure
MIMHYLLFIPASKYARNSGFESLAAEYQQLSLSLDELLVQHPSSTYVEITEGDLMLGEGI
CEEEEEEEECCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCEEECCCC
YDGDLLIVDRHITAQHGADFILLIVNSRLLI
CCCCEEEEECCCCCCCCCCEEEEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]