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The map label for this gene is dppA [H]

Identifier: 160874755

GI number: 160874755

Start: 1979143

End: 1980720

Strand: Reverse

Name: dppA [H]

Synonym: Sbal195_1638

Alternate gene names: 160874755

Gene position: 1980720-1979143 (Counterclockwise)

Preceding gene: 160874756

Following gene: 160874754

Centisome position: 37.04

GC content: 47.85

Gene sequence:

>1578_bases
ATGAGTTGGTTGTTGGTCGCGTGTGGCCCCCAACGACTCCCTTCCGGTTTGGTGTATTGCTCCGAAGGGAACCCTGAGTC
TTTTAATCCACAATTGGTGACGTCTGGCACGACAATCGATGCCACCTCGCACCAAATTTATAGTCGCTTAGTGGATTATG
ATACCCAGTCAGGCAAGCTTGTCCCTGCCTTGGCGACAAGTTGGGCTATGTCCGATGATGGCTTAAGCTATCGCTTCACC
CTCAGGGAAAACGTGCAGTTCCAGCATTCGAAGAGGTTTACCCCAACACGGCCCTTCAATGCCGACGATGTGTTGTTCTC
CTTTAAGCGTATTATCGATACCCAGCATCCTTATCATTTTGTCTCCCGCACGGGTTATCCCTTCTTCCAAAGTATTGGCT
TTTCTGAACAAGTTAAAGGGATAGAAAAGATAAACGATCATGAAGTGGTCTTTTATTTAACCCGCAAAGACGCTTCTTTT
TTATCAAATCTGGCCACCGACTTTGCGGTGATCTTATCCGATGAATATGCGCAGCAGCAGTTAGCCTTGGGTCATCCTGA
AAACGTCGACCACTTTGCCATTGGCACAGGGCCGTTCACTTTAGTTCAGTACGCGAAAAACGAATATATTCGCTATCGCC
GTCATCCTGACTTTTGGGGCGAACCAGCAAAAATTGATATGCTGGTATTTGATATCACGCCAAAAAGTACCGTCAGACTC
GCGAAACTGATCGCGGGGGATTGCAGTGTATCTGCGCTGCCCAAAGCGGGTGAACTGCCCGTTATCAAGCAACATGAAGA
ATTGAATATTGAGTCACAACCTGGACTCAACGTAGCATTTTGGGCCTTTAATACGCAAAAGCCGCCACTGAATGATGTCC
GAGTACGCCGCGCACTGGCCTATGCGGTAGATAAACAAAATATCCTGCGGGCGGTTTATCAAAATACCGCCATTGAAGCC
ACAGGCGTTCTGCCGCCAGCATCTTGGGCCTACGACAATAACAAAGGGCTTGTGGATTACAATCCGCAAAAAGCGCGCGA
CCTATTAAAAGAAGCTGGCATTAAAAATCTCAGTATCGATATTTGGGCTATGCCAGTTGCCCGCGCCTATAACCCCAATG
CGTTAAAAACGGCTGAATTAATTCAATCGGATCTGGCCAACATAGGCGTCAAAGTGAACATCGTCAGTTACGACTGGAGC
GTGTTTAGTCAGCGGCTCAGCCGCGACGACTATGATTCAGTGTTAATTGGCTGGAATGCTGATAATAGCGATCCCGATAA
CTTCTTTACTCCATTGCTGAGCTGCGCCGCAATGCAGTCGAATAACAATCGTTCTCGCTGGTGTAACCCTGAGTTTGATG
CCATCTTAGATAACGCAAGAGAAGTGTCAGATCAGGGCGAACGTAAAGTGATTTATCAACAAGCAGAAGCCTTTTTAGCT
GAACAAGTGCCTATGCTGAGTCTGGCCCATGCCAAACGTGTGGCGTTAACTCGCCATGATGTCAAAGACATGCAACTCAC
GCCTTTTGGGGGCATTTCCTTCGCCCAAACTAGCCAAGCACAAGAGGAGGCGAATTAA

Upstream 100 bases:

>100_bases
GAGATGCACTGCTAAAATAGCCGTTCATAGTCGATAAAATAATGATTTATAAATGAGTGTGCTAATTAGACGCCTGTGCC
TAACAACTGCAGTTTCTTGC

Downstream 100 bases:

>100_bases
TGTTTAAATACCTACTGCGCCGCCTCAATTTGTTCCTTGCCACCTCGTTAGTCATGGTGGGTGTCTTATTTTACGCCACG
GGCTTATTTCCGGTAGATCG

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MSWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDTQSGKLVPALATSWAMSDDGLSYRFT
LRENVQFQHSKRFTPTRPFNADDVLFSFKRIIDTQHPYHFVSRTGYPFFQSIGFSEQVKGIEKINDHEVVFYLTRKDASF
LSNLATDFAVILSDEYAQQQLALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAKIDMLVFDITPKSTVRL
AKLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFNTQKPPLNDVRVRRALAYAVDKQNILRAVYQNTAIEA
TGVLPPASWAYDNNKGLVDYNPQKARDLLKEAGIKNLSIDIWAMPVARAYNPNALKTAELIQSDLANIGVKVNIVSYDWS
VFSQRLSRDDYDSVLIGWNADNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDNAREVSDQGERKVIYQQAEAFLA
EQVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAQTSQAQEEAN

Sequences:

>Translated_525_residues
MSWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDTQSGKLVPALATSWAMSDDGLSYRFT
LRENVQFQHSKRFTPTRPFNADDVLFSFKRIIDTQHPYHFVSRTGYPFFQSIGFSEQVKGIEKINDHEVVFYLTRKDASF
LSNLATDFAVILSDEYAQQQLALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAKIDMLVFDITPKSTVRL
AKLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFNTQKPPLNDVRVRRALAYAVDKQNILRAVYQNTAIEA
TGVLPPASWAYDNNKGLVDYNPQKARDLLKEAGIKNLSIDIWAMPVARAYNPNALKTAELIQSDLANIGVKVNIVSYDWS
VFSQRLSRDDYDSVLIGWNADNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDNAREVSDQGERKVIYQQAEAFLA
EQVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAQTSQAQEEAN
>Mature_524_residues
SWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDTQSGKLVPALATSWAMSDDGLSYRFTL
RENVQFQHSKRFTPTRPFNADDVLFSFKRIIDTQHPYHFVSRTGYPFFQSIGFSEQVKGIEKINDHEVVFYLTRKDASFL
SNLATDFAVILSDEYAQQQLALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAKIDMLVFDITPKSTVRLA
KLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFNTQKPPLNDVRVRRALAYAVDKQNILRAVYQNTAIEAT
GVLPPASWAYDNNKGLVDYNPQKARDLLKEAGIKNLSIDIWAMPVARAYNPNALKTAELIQSDLANIGVKVNIVSYDWSV
FSQRLSRDDYDSVLIGWNADNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDNAREVSDQGERKVIYQQAEAFLAE
QVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAQTSQAQEEAN

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=503, Percent_Identity=45.5268389662028, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1787551, Length=509, Percent_Identity=42.8290766208251, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI1787762, Length=491, Percent_Identity=26.2729124236253, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787052, Length=487, Percent_Identity=24.0246406570842, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1789887, Length=519, Percent_Identity=24.0847784200385, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1789397, Length=503, Percent_Identity=25.4473161033797, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787495, Length=467, Percent_Identity=24.6252676659529, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87081878, Length=494, Percent_Identity=24.2914979757085, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58992; Mature: 58861

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDTQSGKL
CCEEEEECCCCCCCCCEEEECCCCCCCCCCEEEECCCEECCHHHHHHHHHHCCCCCCCEE
VPALATSWAMSDDGLSYRFTLRENVQFQHSKRFTPTRPFNADDVLFSFKRIIDTQHPYHF
EHHHHHHHEECCCCCEEEEEEECCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
VSRTGYPFFQSIGFSEQVKGIEKINDHEVVFYLTRKDASFLSNLATDFAVILSDEYAQQQ
HHCCCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHEEEECCHHHHHH
LALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAKIDMLVFDITPKSTVRL
HHCCCCCCCCEEEECCCHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEECCCCHHHHH
AKLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFNTQKPPLNDVRVRRALA
HHHHHCCCCCCCCCCCCCCCEEECHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
YAVDKQNILRAVYQNTAIEATGVLPPASWAYDNNKGLVDYNPQKARDLLKEAGIKNLSID
HHHCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCEEE
IWAMPVARAYNPNALKTAELIQSDLANIGVKVNIVSYDWSVFSQRLSRDDYDSVLIGWNA
EEECCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHCCCCCCCEEEEECC
DNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDNAREVSDQGERKVIYQQAEAFLA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EQVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAQTSQAQEEAN
HCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHCCCHHHHCC
>Mature Secondary Structure 
SWLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDTQSGKL
CEEEEECCCCCCCCCEEEECCCCCCCCCCEEEECCCEECCHHHHHHHHHHCCCCCCCEE
VPALATSWAMSDDGLSYRFTLRENVQFQHSKRFTPTRPFNADDVLFSFKRIIDTQHPYHF
EHHHHHHHEECCCCCEEEEEEECCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
VSRTGYPFFQSIGFSEQVKGIEKINDHEVVFYLTRKDASFLSNLATDFAVILSDEYAQQQ
HHCCCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHEEEECCHHHHHH
LALGHPENVDHFAIGTGPFTLVQYAKNEYIRYRRHPDFWGEPAKIDMLVFDITPKSTVRL
HHCCCCCCCCEEEECCCHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEEECCCCHHHHH
AKLIAGDCSVSALPKAGELPVIKQHEELNIESQPGLNVAFWAFNTQKPPLNDVRVRRALA
HHHHHCCCCCCCCCCCCCCCEEECHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
YAVDKQNILRAVYQNTAIEATGVLPPASWAYDNNKGLVDYNPQKARDLLKEAGIKNLSID
HHHCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCEEE
IWAMPVARAYNPNALKTAELIQSDLANIGVKVNIVSYDWSVFSQRLSRDDYDSVLIGWNA
EEECCHHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHCCCCCCCEEEEECC
DNSDPDNFFTPLLSCAAMQSNNNRSRWCNPEFDAILDNAREVSDQGERKVIYQQAEAFLA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EQVPMLSLAHAKRVALTRHDVKDMQLTPFGGISFAQTSQAQEEAN
HCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]