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The map label for this gene is sapB [H]

Identifier: 160874754

GI number: 160874754

Start: 1978112

End: 1979143

Strand: Reverse

Name: sapB [H]

Synonym: Sbal195_1637

Alternate gene names: 160874754

Gene position: 1979143-1978112 (Counterclockwise)

Preceding gene: 160874755

Following gene: 160874753

Centisome position: 37.01

GC content: 48.06

Gene sequence:

>1032_bases
ATGTTTAAATACCTACTGCGCCGCCTCAATTTGTTCCTTGCCACCTCGTTAGTCATGGTGGGTGTCTTATTTTACGCCAC
GGGCTTATTTCCGGTAGATCGCACCCACGCACTCACCGGCATACATACACCGACGGCGAGTCAACTGGTTCAAATCGAGC
AGGACTACAAATTAGATAAAAACCAAGCGTGGCAATTTATCGCTTATCTACAACAAAGGCTTAGTGGTAATTTAGGCATT
TCAGTCACCTCACATCAAGAAGTGGCTGAAGAACTCAGCGCCGTCCTACCCGCCTCCTTCGAACTTGCTGTGATGGCGGC
CATTATCGCGATTTGCTTTGGTGTGCCCTTAGGCGTGCTTGCTTCCCAGAGCCAACATAAGCTCACCCAAAATACCATTA
TGGCGATCACGCTAACGGGCTACTCTGTGCCCGTGTTCTGGTTAGGTCTTTATCTTTCGCTCTGGTTTGGTGTCGATCTC
GGTTGGTTACCGATTTCTGGCCAAATCAATTTGTTATATGAAATCAAACCTGTCACTGGCTTTATGTTGGTAGATACCCT
GTTGTCAGAGTCTGAATACGGCATGTCGGCATTTAAAGATGCGCTGCTGCACATCATTTTGCCTGCCACGACACTGGCCG
TGTTACCTTTTACTGTGGTGGTTCGCAGCACGCGATCGGCGATGATGAATGTGATGAATCAAACCTTTATCCGCGCCGCC
GAAGCCAGAGGAATGCATACCGGGACTATTATACTGCGCCACGCCCTACCTAACGCCTTGATCCCCGTGCTGAAACATTT
AGGGTTAATGCTAGGTTCCTTTGCCAGTTATGCCATAGTGGTCGAAATGATTTTCTCTTGGCCTGGCGTGGGGTCTTGGC
TGGTGTCAGGGATTTACCAACGGGACTACACTGTCATCCAAGGTGGTATTTTGGCCGTAGCCCTATTAATTATCTTCCTA
AGTATCTTGATTGAAGTGCTGCATACAGTCTTTAATCCACTGAGCAGAAAAGACCTTTATGCCACCAGTTAA

Upstream 100 bases:

>100_bases
GTGTGGCGTTAACTCGCCATGATGTCAAAGACATGCAACTCACGCCTTTTGGGGGCATTTCCTTCGCCCAAACTAGCCAA
GCACAAGAGGAGGCGAATTA

Downstream 100 bases:

>100_bases
AATTTATCAAGAAGATCAGATTGCCTCACCGACTATGCGGGTTTGGCTTAACTTTTCGGCTAATCCTTTCGCCTTGGCAG
GTCTGTGGACGATTGCTTTC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDKNQAWQFIAYLQQRLSGNLGI
SVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVLASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDL
GWLPISGQINLLYEIKPVTGFMLVDTLLSESEYGMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
EARGMHTGTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQRDYTVIQGGILAVALLIIFL
SILIEVLHTVFNPLSRKDLYATS

Sequences:

>Translated_343_residues
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDKNQAWQFIAYLQQRLSGNLGI
SVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVLASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDL
GWLPISGQINLLYEIKPVTGFMLVDTLLSESEYGMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
EARGMHTGTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQRDYTVIQGGILAVALLIIFL
SILIEVLHTVFNPLSRKDLYATS
>Mature_343_residues
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDKNQAWQFIAYLQQRLSGNLGI
SVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVLASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDL
GWLPISGQINLLYEIKPVTGFMLVDTLLSESEYGMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
EARGMHTGTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQRDYTVIQGGILAVALLIIFL
SILIEVLHTVFNPLSRKDLYATS

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=280, Percent_Identity=41.4285714285714, Blast_Score=241, Evalue=5e-65,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=37.4631268436578, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=29.8816568047337, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1787761, Length=296, Percent_Identity=37.5, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1789888, Length=341, Percent_Identity=29.3255131964809, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1787497, Length=337, Percent_Identity=28.7833827893175, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788504, Length=316, Percent_Identity=20.5696202531646, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37777; Mature: 37777

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCH
NQAWQFIAYLQQRLSGNLGISVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVL
HHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHH
ASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDLGWLPISGQINLLYEIKPVTG
CCCHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCHHH
FMLVDTLLSESEYGMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARGMHTGTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQ
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RDYTVIQGGILAVALLIIFLSILIEVLHTVFNPLSRKDLYATS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFKYLLRRLNLFLATSLVMVGVLFYATGLFPVDRTHALTGIHTPTASQLVQIEQDYKLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCH
NQAWQFIAYLQQRLSGNLGISVTSHQEVAEELSAVLPASFELAVMAAIIAICFGVPLGVL
HHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHH
ASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDLGWLPISGQINLLYEIKPVTG
CCCHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCHHH
FMLVDTLLSESEYGMSAFKDALLHIILPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARGMHTGTIILRHALPNALIPVLKHLGLMLGSFASYAIVVEMIFSWPGVGSWLVSGIYQ
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RDYTVIQGGILAVALLIIFLSILIEVLHTVFNPLSRKDLYATS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]