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The map label for this gene is rlmM [H]

Identifier: 160874510

GI number: 160874510

Start: 1664859

End: 1665944

Strand: Direct

Name: rlmM [H]

Synonym: Sbal195_1392

Alternate gene names: 160874510

Gene position: 1664859-1665944 (Clockwise)

Preceding gene: 160874509

Following gene: 160874512

Centisome position: 31.13

GC content: 47.88

Gene sequence:

>1086_bases
ATGAAAAACCTATTTTTATTTTGCCGCGCAGGCTTTGAAAAAGAATGCGCTGCAGAAATCCAACAGCGAGCCGGTGAGCT
CAATGTGGGTGGCTTTGTTAAGGCCAACAATAACGACGCCTATGTCGTGTACCAATGTTTTGAAGATGACGCCGCAGATA
CGTTAGTGAAACAACTGCCCTTAGATTCGCTCATTTTCGCTCGCCAGATGTTTGCTGCCAGCGACTTATTAGTCGACTTG
CCTGAAAATGACAGAATTAGCCCAATCGTGGCGGCACTCAGTGACGTCAGCAAAGCGGGCGAAGTGCGGGTTGAAACGCC
AGATACTAACGAAGCGAAAGAGCTATCGGCTTTTTGCCGTAAGTTCACTGTGCCTTTACGCCAGCATTTGAAAAAATCTG
GCAGTTTGCTCGCGCAGGAAAATCCAAAACGTCCGATTATCCACGTGTGTTTTATCGGACCCGGCCGTGCCTATGTGGGT
TATTCCTACAGCAATAACAGCTCGCCACATTTTATGGGTATTCCACGTCTGAAAATGGCGGCGGATGCTCCGAGTCGTTC
TAGCCTGAAACTCGATGAAGCCTTTGGCCAGTTCGTGCCTAAGGAAGAGCAAGAAGAGCGTATTCGCAGTGGCATGAACT
CAGTGGATTTGGGCGCTTGTCCAGGTGGCTGGACTTATCAACTGGTGCGTCGTGGCATGTTTGTCTCGGCTGTCGATAAT
GGTCCCATGGATGAAAAACTGATGGAAACGGGCCAAGTGAAACATTACCGTGAAGACGGTTTCCGTTTCGAGCCACAGCG
CAAAAATATCTATTGGCTAGTGTGCGACATGGTTGAGAAACCAGCGCGCGTTGCCGAACTGATTGAAGCTTGGGCGATTA
ACGGTTGGTTTAAGGAAGCGATTTTCAACCTTAAATTACCGATGAAGAGCCGCTATAAAGAAGTCACTGCCATTCTTGAG
ACCATGCAGACCATTCTTAAAGAAAATGGCGTGAGCGATTTTAAAGTGCAGTGTAAGCATCTTTATCACGATCGTGATGA
AGTGACAGTGCATTTATGGCTGCGTCCTAATACCGCGTGGAATTAA

Upstream 100 bases:

>100_bases
CCGCAGTAGGCAAATAGGGCATTTGTGGATTGAAATTGGTATACTGACGCCCAAATCGATAGTCAGCCAATGCTTTGGCT
TGGATTTCTCAGGGATCCCC

Downstream 100 bases:

>100_bases
TTCCTGCGATAACTCTGCAGTGATATTACCGTCGTTACTCGCGTACGTTACTTAGGTACGCTAATACGGTAATACGGTAA
TACGGTAATACGGTAATCGT

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLPLDSLIFARQMFAASDLLVDL
PENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVG
YSYSNNSSPHFMGIPRLKMAADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVTAILE
TMQTILKENGVSDFKVQCKHLYHDRDEVTVHLWLRPNTAWN

Sequences:

>Translated_361_residues
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLPLDSLIFARQMFAASDLLVDL
PENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVG
YSYSNNSSPHFMGIPRLKMAADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVTAILE
TMQTILKENGVSDFKVQCKHLYHDRDEVTVHLWLRPNTAWN
>Mature_361_residues
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLPLDSLIFARQMFAASDLLVDL
PENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVG
YSYSNNSSPHFMGIPRLKMAADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVTAILE
TMQTILKENGVSDFKVQCKHLYHDRDEVTVHLWLRPNTAWN

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=353, Percent_Identity=59.2067988668555, Blast_Score=446, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 40954; Mature: 40954

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLP
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHCC
LDSLIFARQMFAASDLLVDLPENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCR
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVGYSYSNNSSPHFMGIPRLKMA
HHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEECCCCHHEC
ADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
CCCCCCCCEEHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCC
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEA
CCCHHHHHHHCCHHHHHCCCCEECCCCCCEEEEEECHHHCHHHHHHHHHHHHCCHHHHHH
IFNLKLPMKSRYKEVTAILETMQTILKENGVSDFKVQCKHLYHDRDEVTVHLWLRPNTAW
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC
N
C
>Mature Secondary Structure
MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLP
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHCC
LDSLIFARQMFAASDLLVDLPENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCR
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
KFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVGYSYSNNSSPHFMGIPRLKMA
HHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEECCCCHHEC
ADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNSVDLGACPGGWTYQLVRRGMFVSAVDN
CCCCCCCCEEHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCC
GPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEA
CCCHHHHHHHCCHHHHHCCCCEECCCCCCEEEEEECHHHCHHHHHHHHHHHHCCHHHHHH
IFNLKLPMKSRYKEVTAILETMQTILKENGVSDFKVQCKHLYHDRDEVTVHLWLRPNTAW
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA